Search clinical trials for: MAP Kinase Signaling Pathway
Total 12610 results
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Assiut UniversityCompleted
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Xie KangjieRecruitingDiabetes | Postoperative DeliriumChina
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Tianjin Medical University Cancer Institute and...RecruitingNon-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle DeregulationChina
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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Memorial Sloan Kettering Cancer CenterRecruitingSolid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene MutationUnited States
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D3 Bio (Wuxi) Co., LtdRecruitingAdvanced Solid Tumors With MAPK Pathway MutationsAustralia, China, United States
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Jazz PharmaceuticalsRecruitingSolid Tumor | Metastatic Cancer | Advanced CancerUnited States
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M.D. Anderson Cancer CenterNovartis; Puma Biotechnology, Inc.; Celcuity IncRecruiting
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Pancreatic Ductal AdenocarcinomaUnited States
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Second Affiliated Hospital of Guangzhou Medical...RecruitingHepatocellular Carcinoma | Solid Tumor, AdultChina
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MapKure, LLCRecruitingSolid Tumor | B-Raf Mutation-Related TumorsUnited States, Australia
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St. Jude Children's Research HospitalNovartis PharmaceuticalsActive, not recruitingGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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National Cancer Institute (NCI)Active, not recruitingUterine Cervical Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Carcinoma, Neuroendocrine | Extrapulmonary Small Cell Cancer | Carcinoma, Non-Small -Cell LungUnited States
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JS InnoPharm, LLCSuspended
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St. Justine's HospitalCHU de Quebec-Universite Laval; Montreal Children's Hospital of the MUHCActive, not recruitingLow-grade Glioma | Plexiform Neurofibroma | Central Nervous System GliomaCanada
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Erasca, Inc.CompletedAdvanced Non-squamous Non-small-cell Lung CancerUnited States
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Basilea PharmaceuticaArQule, Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary...CompletedSolid TumorUnited States, Italy
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Academisch Medisch Centrum - Universiteit van Amsterdam...CompletedMetastatic Pancreatic Cancer | Locally Advanced Pancreatic CancerNetherlands
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Novartis PharmaceuticalsCompletedMetastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
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ArQule, Inc. (a wholly owned subsidiary of Merck...TerminatedOvarian Cancer | Endometrial Cancer | Solid TumorsUnited States
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Bristlecone Health, Inc.University of MinnesotaCompletedMetabolic Syndrome | Mild Cognitive ImpairmentUnited States
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The Netherlands Cancer InstituteMerck Sharp & Dohme LLCUnknownMetastatic MelanomaNetherlands
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Yonsei UniversityCompletedPatients With Elective Aortic Valve ReplacementKorea, Republic of
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Shanghai Changzheng HospitalCompleted
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Ziauddin UniversityNot yet recruitingOral Submucous FibrosisPakistan
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingNoonan Syndrome | Costello Syndrome | RASopathy | Cardio-Facio-Cutaneous SyndromeItaly
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationAustralia
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University of Alabama at BirminghamNot yet recruitingCardiovascular Diseases | Obesity | Insulin Sensitivity/Resistance | Metabolic Disease | Energy Expenditure | MetabolismUnited States
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Suzhou Genhouse Bio Co., Ltd.Shanghai East Hospital; Shandong Tumor HospitalRecruitingAdvanced Solid Tumors With MAPK Signal Pathway MutantChina
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Imperial College LondonBarking, Havering and Redbridge University Hospitals NHS Trust; Imperial College... and other collaboratorsRecruitingQuality of Life | Oesophageal Cancer | Bacterial OvergrowthUnited Kingdom
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Ikena OncologyRecruitingColorectal Cancer | Pancreatic Cancer | Thyroid Carcinoma | Solid Tumor, Adult | Malignant Melanoma | Non-Small Cell Lung Carcinoma | BRAF Gene Mutation | Gliomas, Malignant | Ras (Kras or Nras) Gene Mutation | CRAF Gene MutationUnited States
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Immuneering CorporationRecruitingPancreas Adenocarcinoma | Non-small Cell Lung Cancer | Advanced Solid Tumor (Phase 1) | Malignant Melanoma (Cutaneous)United States
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Pamela MunsterNational Cancer Institute (NCI)RecruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene MutationUnited States
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Fondazione IRCCS Ca' Granda, Ospedale Maggiore...University of Trieste; IRCCS Fondazione Stella Maris; CNR Institute of Neuroscience...Recruiting
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Murdoch Childrens Research InstituteRoyal Children's Hospital; Peter MacCallum Cancer Centre, AustraliaNot yet recruitingArteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditionsAustralia
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RenJi HospitalThe First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaboratorsRecruitingMetastatic Renal Cell CarcinomaChina
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Black Diamond Therapeutics, Inc.RecruitingMelanoma | Colorectal Cancer | NSCLC | Solid Tumor | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Non-small Cell Lung Cancer | Histiocytosis | Melanoma (Skin) | Recurrent Melanoma | Thyroid Carcinoma | Thyroid Cancer | Brain Metastases | Recurrent Histiocytic and Dendritic... and other conditionsUnited States
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Novartis PharmaceuticalsRecruitingNon-Small-Cell Lung CarcinomaKorea, Republic of
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Centre Hospitalier Universitaire de LiegeSanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaboratorsRecruitingCongenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditionsBelgium
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Cedars-Sinai Medical CenterNational Institute on Aging (NIA)RecruitingObesity | Healthy LifestyleUnited States
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SWOG Cancer Research NetworkNational Cancer Institute (NCI)RecruitingStage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell CarcinomaUnited States
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Shaw Cancer CenterSteadman Philippon Research InstituteRecruitingRadiation Induced FibrosisUnited States
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University of California, San DiegoRecruiting
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Immuneering CorporationRecruitingPancreatic Adenocarcinoma | Advanced Solid Tumor | Non-small Cell Lung Cancer (NSCLC) | Malignant Melanoma (Cutaneous)United States
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Mirati Therapeutics Inc.RecruitingSolid Tumor | Non Small Cell Lung Cancer | Advanced Solid Tumor | Colo-rectal CancerUnited States, Puerto Rico
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Qilu Pharmaceutical Co., Ltd.RecruitingAdvanced Solid Tumors Harboring MAPK Pathway AlterationsChina
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Navire Pharma Inc., a BridgeBio companyAmgenRecruitingNon Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Metastatic NSCLCSpain, Australia, France, Denmark, Greece, Italy, Netherlands
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Navire Pharma Inc., a BridgeBio companyBristol-Myers SquibbRecruitingSolid Tumor | Non Small Cell Lung CancerUnited States
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Beijing Tongren HospitalPeking University People's Hospital; Beijing Shijitan Hospital, Capital Medical...Recruiting