Search clinical trials for: MDS, Fatigue, RBC transfusion

Total 1696 results

Sakarya University

Not yet recruiting

"ADE Fibrinogen/RBC" Ratio on Mortality and Outcome in Massive Transfusion Patients (ADEFES)

Massive Transfusion
Associazione Qol-one

Recruiting

Efficacy and Safety of Luspatercept for the Treatment of Anemia Due to MDS With del5q, Refractory/Resistant/Intolerant to Prior Treatments, RBC-TD (Phoenix)

Myelodysplastic Syndromes | Anemia | Transfusion-dependent Anemia | Del(5Q)

Italy
Bristol-Myers Squibb

Recruiting

A Study to Determine the Efficacy and Safety of Luspatercept in Adult and Adolescent Participants With Alpha (α)-Thalassemia

Anemia

Thailand, China, Canada, Turkey, Greece, Taiwan, Italy, Hong Kong
McMaster University
CBS

Recruiting

Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes? (UD)

Myelodysplastic Syndrome

Canada
University Hospital, Basel, Switzerland

Recruiting

Perioperative Management in Gynaecological Carcinoma Surgery

Gynaecological Carcinoma

Switzerland
Phoenicia BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

The BENeFiTS Trial in Beta Thalassemia Intermedia (PB04-001)

Sickle Cell Disease | Beta Thalassemia Intermedia

United States, Canada
RenJi Hospital

Not yet recruiting

Effects of Packed Red Blood Cell Storage Duration on Pediatric Living Donor Liver Transplantation

Transfusion Related Complication
Children's Hospital of Philadelphia
National Heart, Lung, and Blood Institute (NHLBI); New York Blood Center

Recruiting

RH Genotype Matched RBC Transfusions (RBC)

Sickle Cells Disease

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); Columbia University

Recruiting

The Impact of Oxidative Stress on Erythrocyte Biology (RBC Survival)

Sickle Cell Disease Without Crisis

United States
Daping Hospital and the Research Institute of Surgery...

Recruiting

Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates

Acute Respiratory Distress Syndrome (ARDS) | Red Blood Cells(RBC)

China
Cerus Corporation

Recruiting

INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS)

Anemia

United States, Puerto Rico
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

RBC Irradiation, Anemia and Gut Injury (RBC-mNIRS)

Anemia | Necrotizing Enterocolitis

United States
National Institutes of Health Clinical Center (CC)

Completed

Molecular Immunohematology in Ethiopian Sub-Populations

Immunohematology

Ethiopia
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

SAHaRA: A Randomized Controlled Trial

Subarachnoid Hemorrhage, Aneurysmal

United States, Canada, Australia
Westat
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients (RBC-IMPACT)

Sickle Cell Disease | Thalassemia | Pediatric Cancer

United States, Brazil
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); Canadian Critical Care Trials... and other collaborators

Completed

HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN: The HEMOTION Trial (HEMOTION)

Traumatic Brain Injury | Transfusion

Canada, United Kingdom, Brazil, France
Clinica Universidad de Navarra, Universidad de...
Hospital Clinic of Barcelona; Hospital Son Espases; Hospital del Mar; Hospital... and other collaborators

Active, not recruiting

Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR) (TScoreBTR)

Surgery | Brain Tumor Adult | Transfusion

Spain
Terumo BCTbio
United States Department of Defense; U.S. Army Medical Research and Development... and other collaborators

Terminated

Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE) (PRAISE)

Transfusion Dependent Thalassemia

United States, Israel, Italy, Turkey
Celgene

Completed

The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States, Australia, Canada, Czechia, France, Germany, Italy, Korea, Republic of, Mexico, Poland, Sweden, United Kingdom, Belgium, Brazil, Denmark, Finland, Greece, Israel, Netherlands, Norway, Portugal, Spain, Turkey
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Active, not recruiting

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve (COMMANDS)

Myelodysplastic Syndromes

United States, Australia, Austria, Belgium, Canada, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Netherlands, Poland, Portugal, Russian Federation, Spain, Sweden, Switzerland, Taiwan, Turke... and more
Cristina Martinez

Completed

Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage

Hemorrhagic Shock

Spain
University of Minnesota

Active, not recruiting

Clinical Impact of Red Cell Storage Age

RBC Transfusions

United States
Celgene

Completed

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

Primary Myelofibrosis | Anemia

United States, France, Italy, United Kingdom
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Transfusion of Biotinylated Red Blood Cells (b-RBCs)

Anemia

United States
Daping Hospital and the Research Institute of Surgery...
Children's Hospital of Chongqing Medical University

Withdrawn

Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis

Anemia | Necrotizing Enterocolitis | Red Blood Cell (RBC) Transfusion

China
University Hospitals Cleveland Medical Center

Terminated

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

Hypoxia

United States
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Blood Services

Active, not recruiting

An Innovative Trial Assessing Donor Sex on Recipient Mortality (iTADS)

Red Blood Cell Transfusion

Canada
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Leiden University Medical Center

Completed

R-FACT Study:Risk Factors for Alloimmunization After Red Blood Cell Transfusions (R-FACT)

Hemolysis

Netherlands
Università degli Studi di Ferrara

Completed

Impact of the Preparation Method of Red Cell Concentrates on Transfusion Indices in Thalassemic Patients

Thalassemia Major

Italy
John A Widness
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Red Blood Cell (RBC) Survival Following Transfusion in Infants

Neonatal Anemia

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Deferasirox in Patients With Chronic Anemia and Transfusional Hemosiderosis

Transfusional Hemosiderosis | Chronic Anemia

Japan, Turkey, Spain, Poland, Singapore
Angel Augusto Perez Calatayud
Grupo Mexicano para el Estudio de la Medicina Intensiva

Completed

Patient Blood Management for Massive Obstetric Hemorrhage

Post Partum Hemorrhage | Transfusion Related Complication | Fibrinogenolysis; Hemorrhage | Fibrinogen; Deficiency, Acquired | Massive Hemorrhage

Mexico
The Cleveland Clinic

Completed

Red Cell Storage Duration and Outcomes in Cardiac Surgery

Cardiac Surgery | Blood Transfusion

United States
Fundación Universitaria de Ciencias de la Salud
Hospital de San Jose

Completed

Is Red Blood Cell Transfusion a Risk Factor for Vascular Pedicle Thrombosis? The Study Case of a Latin American Cohort (RBCT)

Vascular Thrombosis
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Age of Blood in Children in Pediatric Intensive Care Units (ABC-PICU)

Anemia

United States, Canada, France, Israel, Italy
John A Widness
National Heart, Lung, and Blood Institute (NHLBI); Janssen Scientific Affairs... and other collaborators

Completed

Optimized Erythropoietin (EPO) Treatment (OETNA)

Neonatal Anemia

United States
Mayo Clinic
Duke University; Blood Systems Research Institute

Completed

Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications

Blood Transfusion Complications

United States
Hospital General de Niños Pedro de Elizalde

Completed

Erythropoietin in Hemolytic Uremic Syndrome

Anemia | Hemolytic-Uremic Syndrome

Argentina
Duke University
Zimmer Biomet

Terminated

Rejuvenated RBC and VO2 Max in Healthy Subjects

Erythrocyte Transfusion

United States
University of Texas Southwestern Medical Center
AMAG Pharmaceuticals, Inc.

Terminated

Active Preoperative Anemia Management in Patients Undergoing Cardiac Surgery (APART)

Cardiovascular Disease | Anemia

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

TACO Crossover TRIAL

Transfusion-associated Circulatory Overload | Blood Transfusion Reaction

Netherlands
Brigham and Women's Hospital

Terminated

Trial of Feedback on Blood Use (TOFU)

Compliance With Restrictive RBC Transfusion Guideline

United States
University of California, San Francisco

Terminated

Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Myeloid Malignancy | Metabolic Disease | Bone Marrow Failure Syndrome | Transfusion-dependent Red Blood Cell (RBC) Defect | Congenital Immunodeficiency | Severe Immune Dysregulation

United States
Oregon Health and Science University
United States Air Force; Armed Services Blood Program

Completed

Frozen Red Blood Cell Transfusions in Trauma Patients

Anemia | Trauma | Blood Loss

United States
New York Blood Center
Westchester Medical Center

Withdrawn

POOLED Red Blood Cells Prepared From Pooling 5 Leukoreduced, Irradiated RBC Units (Pooled RBCs)

Anemia | Transfusion Reaction

United States
Weill Medical College of Cornell University
Celgene

Terminated

Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes

Myelodysplastic Syndrome

United States
Celgene

Completed

Study of Pomalidomide in Persons With Myeloproliferative-Neoplasm-Associated Myelofibrosis and RBC-Transfusion-Dependence (RESUME)

Primary Myelofibrosis | MPN-associated Myelofibrosis

United States, Netherlands, France, Australia, Italy, United Kingdom, Canada, Germany, China, Spain, Belgium, Austria, Poland, Sweden, Japan, Russian Federation
Emory University

Terminated

Physiologic Effects of RBC Transfusion

Red Blood Cell Transfusion

United States
Duke University

Completed

Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions

Sickle Cell Disease

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Red Cell Transfusion Goals in Patients With Acute Leukemias

Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia (AML) | Acute Lymphocytic Leukemia (ALL) | Acute Promyelocytic Leukemia (APL)

United States

Search clinical trials for: MDS, Fatigue, RBC transfusion

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