Search clinical trials for: Mastocytosis

Total 102 results

Hong Kong Sanatorium & Hospital
Chinese University of Hong Kong; Stanford University

Completed

Mast Cell Activation Test in Allergic Disease

Asthma | Eczema | Food Allergy | Mastocytosis | Chronic Idiopathic Urticaria | Anaphylaxis | Mast Cell Activation Syndrome

Hong Kong
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Germany, Italy
National Institute of Allergy and Infectious Diseases...

Completed

Cause and Natural Course of Pediatric-Onset Mastocytosis

Mastocytosis

United States
AB Science

Completed

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis (AB06006)

Indolent Systemic Mastocytosis

France, United States
National Institute of Allergy and Infectious Diseases...

Terminated

Evaluation and Long-Term Follow-Up of Patients With Allergic and Inflammatory Disorders

Asthma | Allergy | Allergic Rhinitis | Atopic Dermatitis | Food Allergy | Mastocytosis

United States
Meir Medical Center

Completed

The Significance of Blood-tryptase and c-Kit Mutation in Insect Venom Immunotherapy

Hypersensitivity, Immediate | Mastocytosis | Insect Bites and Stings

Israel
University Hospital, Toulouse

Completed

Adaptation of the Questionnaire "Regarding Patient's Quality of Life With Mastocytosis" in the French Language (Mc_QoL)

Indolent Systemic Mastocytosis | Cutaneous Mastocytosis

France
University Hospital, Toulouse

Completed

Diagnostic Value of Bone Marrow Tryptase in Systemic Mastocytosis (EvaTryMS)

Systemic Mastocytosis

France, Martinique
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
Allakos Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK002

Indolent Systemic Mastocytosis

Germany
Jason Robert Gotlib
Seagen Inc.

Completed

Brentuximab Vedotin in Treating Patients With Advanced Systemic Mastocytosis or Mast Cell Leukemia

Systemic Mastocytosis | Mast Cell Leukemia | Aggressive Systemic Mastocytosis

United States
AB Science

Completed

Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Mastocytosis
AB Science

Completed

Masitinib in Patients With Mastocytosis With Handicap and Bearing the D816V Mutation

Mastocytosis
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia

Leukemia

United States, Belgium, Netherlands, Canada, Austria, Germany, Australia, United Kingdom, Turkey, France, Poland, Norway
Bayer

Withdrawn

Outcomes of mCRPC Patients Treated With Ra-223 Concomitant With Abiraterone or Enzalutamide- A Chart Review Study

Prostatic Neoplasms, Castration-Resistant
Jason Robert Gotlib
Novartis; Novartis Pharmaceuticals

Completed

Phase 2 Midostaurin in Aggressive Systemic Mastocytosis and Mast Cell Leukemia

Systemic Mastocytosis, Aggressive (ASM) | Leukemia, Mast Cell | Hematological Non-mast Cell Lineage Disease (AHNMD)

United States
Jason Robert Gotlib
National Cancer Institute (NCI)

Terminated

Ibrutinib in Treating Patients With Advanced Systemic Mastocytosis

Systemic Mastocytosis | Mast Cell Leukemia | Aggressive Systemic Mastocytosis

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

Juvenile Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Childhood Acute Lymphoblastic Leukemia | Prolymphocytic Leukemia | Hairy Cell Leukemia | Acute Undifferentiated Leukemia | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Childhood Acute Myeloid... and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Burkitt Lymphoma | Secondary... and other conditions

United States
PTC Therapeutics

Completed

An Open-Label, Long-Term Extension Study to Evaluate the Safety and Tolerability Deflazacort

Duchenne Muscular Dystrophy

United States
Stanford University
National Cancer Institute (NCI); The Leukemia and Lymphoma Society

Completed

Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD

Leukemia, Mast-Cell | Mantle-cell Lymphoma

United States
Medical University of Graz

Unknown

Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases (BioUV2017)

Lymphoproliferative Disorders | Psoriasis | Eczema | Pruritus | Vitiligo | Cutaneous T Cell Lymphoma | Mastocytosis | Graft Vs Host Disease | Lichen Planus | Prurigo | Polymorphic Light Eruption

Austria
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Transplantation to Treat Systemic Mastocytosis

Mastocytosis

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

HIV Infection | Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal... and other conditions

United States
Novartis Pharmaceuticals

Completed

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Chronic Myelomonocytic Leukemia | Hypereosinophilic Syndrome | Systemic Mastocytosis | Dermatofibrosarcoma

Australia
Adelphi Values LLC
Blueprint Medicines Corporation

Completed

Patient-Reported Outcome Questionnaire for Systemic Mastocytosis

Mast Cell Leukemia (MCL) | Aggressive Systemic Mastocytosis (ASM) | SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD) | Smoldering Systemic Mastocytosis (SSM) | Indolent Systemic Mastocytosis (ISM) ISM Subgroup Fully Recruited

United States
Novartis Pharmaceuticals

Completed

Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases

Life Threatening Diseases
University of Michigan

Completed

Molecular Mechanisms and Diagnosis of Mastocytosis

Mastocytosis

United States
Marcus Maurer

Completed

Study on Mastocytosis for Rupatadine Treatment (SMART)

Mastocytosis

Germany
Patara Pharma

Completed

Treatment of Indolent Systemic Mastocytosis With PA101

Systemic Mastocytosis | Mastocytosis | Indolent Systemic Mastocytosis

France, Germany, Spain, Italy, Netherlands
Hospital Virgen de la Salud

Completed

Imatinib in KIT-negative Systemic Mastocytosis

Systemic Mastocytosis

Spain
Hospital Virgen de la Salud

Unknown

Cladribine Plus Pegylated Interpheron Alfa-2a in Systemic Mastocytosis

Systemic Mastocytosis

Spain
Centre Hospitalier Universitaire, Amiens

Completed

Thalidomide in Treating Patients With Relapsed or Progressive Systemic Mastocytosis

Precancerous Condition | Non Neoplastic Condition

France
University of Zurich

Completed

The Effect of Xolair ® (Omalizumab) in Mastocytosis Patients (XOLMA)

Mastocytosis

Switzerland
Centre Antoine Lacassagne

Terminated

Evaluation of Patient Satisfaction With and Acceptance of Their Totally-implanted Central Venous Catheter (QASICC-EVA)

Malignant Mast Cell Tumors | Solid Organ Sites

France
University Medical Center Groningen

Unknown

Midostaurin in Indolent Systemic Mastocytosis

Indolent Systemic Mastocytosis

Netherlands
National Cancer Institute (NCI)

Terminated

Sunitinib in Treating Patients With Idiopathic Myelofibrosis

Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
National Cancer Institute (NCI)

Completed

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy

HIV Infection | Clear Cell Renal Cell Carcinoma | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States
LEO Pharma

Terminated

Cromoglicate in Mastocytosis

Mastocytosis

Germany
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis

Lymphoma | Leukemia | Chronic Myeloproliferative Disorders | Precancerous Condition | Nonneoplastic Condition

United States
M.D. Anderson Cancer Center

Completed

Ontak (Denileukin Diftitox) in Patients With Systemic Mastocytosis (SM)

Leukemia | Systemic Mastocytosis

United States
M.D. Anderson Cancer Center
Gemin X

Terminated

Obatoclax for Systemic Mastocytosis

Leukemia | Systemic Mastocytosis

United States
Federico II University
University of Bologna

Unknown

Evaluation of Response of Dasatinib to Treat Mastocytosis

Systemic Mastocytosis

Italy
Medical College of Wisconsin
Society for Pediatric Dermatology

Completed

Natural History of Urticaria Pigmentosa in Children (UP)

Urticaria Pigmentosa

United States
National Institute of Allergy and Infectious Diseases...

Completed

Blood Factors in Mastocytosis and Unexplained Anaphylaxis and Flushing

Mastocytosis | Anaphylaxis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Characteristics of Mast Cells in Mastocytosis

Mastocytosis

United States

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