Search clinical trials for: Maximum plasma concentration

Total 9235 results

Seoul National University Hospital

Not yet recruiting

Reduction of Remifentanil-related Complications

Anesthesia

Korea, Republic of
Pfizer

Completed

Evaluation of the Relative Bioavailability of Bosutinib Capsules Under Fed Condition and Estimation of Food Effect on Orally Administered Bosutinib Capsule

Healthy Participants

Belgium
Pfizer

Completed

Bioavailability of Bosutinib Administered as Capsule Contents Mixed With Applesauce or Yogurt Relative to Intact Capsules Under Fed Condition

Healthy Participants

Belgium
PepsiCo Global R&D

Completed

Processed Orange and the Glycemic Response (POGR)

Maximum Observed Plasma Glucose Concentration (Cmax)

United States
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma

Lymphoma | Nonhematologic Malignancies

United States
University of Zurich
Stanford University

Terminated

Study for Identifying Optimal Simvastatin Formulation for Uniform Time to Maximum Plasma Concentration

Celiac Disease

Switzerland
Lundbeck LLC

Withdrawn

An Open-Label, Single and Multiple Oral Dose Pharmacokinetic Study of Vigabatrin in Infants With Infantile Spasms

Infantile Spasms
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients With Advanced GISTs

Gastrointestinal Stromal Tumors
University Hospital Center of Martinique
Institut Pasteur de Guadeloupe; Centre de Ressources Biologiques de la Martinique...

Not yet recruiting

Systemic Lupus Erythematosus and Chlordecone Impregnation in Martinique (LUNEK)

Systemic Lupus Erythematosus | Renal Disease

France
University of North Carolina, Chapel Hill
Bausch Health Americas, Inc.

Not yet recruiting

Rifaximin for the Secondary Prevention of Recurrent Pouchitis

Pouchitis

United States
University of Copenhagen
Stanford University

Recruiting

Is the Plasma Concentration of CAPGDF15 Increased in Pregnancy? A Pilot Study (CAP)

Pregnancy Related

Denmark
Affiliated Hospital of Nantong University

Not yet recruiting

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Depression | Polymerase Chain Reaction | Polymorphism, Genetic | CYP1A2 Polymorphism | Plasma Concentration | CYP2C9 Polymorphism
University Hospital, Caen

Recruiting

Relation Between Venetoclax Plasma Concentration and Remission in Adults With Acute Myeloid Leukemia (PREDICLAX)

Adult Acute Myeloid Leukemia

France
University Hospital, Ghent
Imec; Research Foundation Flanders

Not yet recruiting

Validation of Betalactam ML Prediction Models - TDMAide (TDMAide)

Infections

Belgium
University Hospital Center of Martinique
University Hospital, Limoges; Reims University Hospital; BioGaia AB; Regional Health... and other collaborators

Not yet recruiting

Effects of Probiotic Oral Intake on Plasma Chlordecone (Kepone) Concentrations in Individuals Environmentally Exposed to Pesticide in Martinique. (CHLOR-DETOX)

Chlordecone (Kepone) Toxicity

Martinique
University Hospital, Caen

Not yet recruiting

Relation Between Psychoactive Drugs Overdosage and Severity of Falls in Elderly People (MEDIFALL)

Fall
Medical College of Wisconsin

Not yet recruiting

Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma

Multiple Myeloma
National Nutrition and Food Technology Institute

Not yet recruiting

The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measurements, Concentrations of Thyroid Hormones, Anti-TPO, and Systemic Inflammation in Plasma and NFK-B in Peripheral Blood Mononuclear Cells in Patients With Hashimato

Hypothyroidism | Thyroid Diseases | Hashimoto Disease

Iran, Islamic Republic of
Technische Universität Dresden
German Cancer Research Center

Recruiting

A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies (CARLOTTA01)

Neoplasms | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Relapsed Diffuse Large B-cell Lymphoma (DLBCL) | Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Germany
Indonesia University

Recruiting

Comparing Platelet-Rich Plasma (PRP) Centrifugation Methods on Thrombocyte Concentration and Clinical Improvement of Androgenetic Alopecia

Alopecia, Androgenetic

Indonesia
Hospices Civils de Lyon

Recruiting

Hypovitaminosis C Prevalence and Risk Factors in an Acute Geriatric Unit (HYPO-VIT-C)

Deficiency, Vitamin C

France
University Hospital, Basel, Switzerland

Recruiting

Target Attainment of Continuous Infusion Flucloxacillin and Cefazolin Coupled With TDM vs. Standard of Care Treatment in Patients With Complicated S. Aureus Infection (TARGET III)

Complicated Staphylococcus Aureus (S. Aureus) Infections (CSAI)

Switzerland
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Maximum Alveolar Concentration of Sevoflurane for Maintaining Effective Spontaneous Respiration (MaACesr)

Sevoflurane

China
University of Turin, Italy

Recruiting

Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery

Postoperative Pain | Regional Anesthesia Morbidity | Local Anesthetic Toxicity

Italy
University Hospital, Basel, Switzerland

Recruiting

Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia (PROPHECY)

Thiazide-induced Hyponatremia (TIH)

Switzerland
First Affiliated Hospital of Zhejiang University

Recruiting

Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

Severe Sepsis

China
Medical University of Silesia

Recruiting

Neurogenic Myocardial and Lung Injury in SAH Patients

Myocardial Injury | Lung Injury | Subarachnoid Hemorrhage

Poland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Early Oseltamivir Carboxylate Low Plasma Concentration in Patients Admitted to Intensive Care for Severe Influenza (OPTIFLU)

Severe Influenza

France
Centre Hospitalier Universitaire, Amiens

Recruiting

Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery (LARA)

Analgesia | Thoracic Epidural Analgesia | Lidocaine Adverse Reaction | Abdominal Surgery by Laparotomy

France
Assiut University

Not yet recruiting

Serum Rennin Kinetics Versus Serum Lactate Kinetics as Predictors of Mortality in Septic Shock Patients

Septic Shock
Tianjin Medical University General Hospital

Not yet recruiting

Effect of Ultrasound-guided Transversus Abdominis Plane Block After Laparoscopic Bariatric Surgery

Postoperative Pain | Postoperative Nausea and Vomiting
Assistance Publique Hopitaux De Marseille

Recruiting

Real-time Monitoring of Concentration and Size Variations of Circulating Plasma Free DNA to Predict Early Response to Immunotherapies in Patients With Different Types of Cancer. (SCHISM)

Cancer

France
The First Affiliated Hospital of Soochow University
Shandong Provincial Hospital; Qingdao Municipal Hospital; Central South University and other collaborators

Not yet recruiting

Optimal Adalimumab Plasma Concentrations in Ankylosing Spondylitis Patients

Ankylosing Spondylitis

China
Bexion Pharmaceuticals, Inc.
CTI Clinical Trial and Consulting Services

Recruiting

A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (KONQUER)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
Nantes University Hospital

Recruiting

Validation Study of a New Cytokine-based Dynamic Stratification Based on FLt3 Ligand Plasma Concentration Kinetic Profile and IL-6 Concentration During Induction of Acute Myeloid Leukemia (FLAMVAL)

Acute Myeloid Leukemia

France
Hospices Civils de Lyon

Recruiting

Post-operative Analgesic Effect of Oral Nefopam (NefPO)

Postoperative Pain After a Total Knee Arthroplasty

France
Medical University of Warsaw

Recruiting

TMAO in Patients With Severe Aortic Stenosis (TASTE)

Heart Failure | Aortic Stenosis

Poland
University of Pecs

Recruiting

Plasma Concentration of Somatostatin and Endocannabinoids After GA and RA in Upper Extremity Trauma Surgery (SECsGRUES)

Postoperative Pain | Arm Injury

Hungary
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Paul M. Tulkens

Recruiting

Plasma Protein Binding and PK/PD of Total and Unbound Temocillin Non-ICU Patients (TEMODELTA)

Pharmacokinetics | Infection | Infections, Bacterial | Drug Monitoring | Antibacterial Agents | Temocillin

Belgium
National Taiwan University Hospital

Recruiting

Investigation of the Correlation Between Plasma Concentration of Linezolid Antibiotic and Treatment Response and Adverse Reactions

Peripheral Neuropathy | Lactic Acidosis | Myelosuppression

Taiwan
National Institute of Diabetes and Digestive and...

Recruiting

Urinary Vitamin C Loss in Diabetic Subjects

Diabetes

United States
Baylor College of Medicine

Completed

Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population

Anesthesia, Local

United States
University of Guadalajara

Completed

Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment

Human Immunodeficiency Virus

Mexico
University of Toledo Health Science Campus

Completed

Platelet Rich Plasma in Knee Osteoarthritis

Knee Osteoarthritis

United States
Asceneuron S.A.

Completed

Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51

Alzheimer Disease

United Kingdom
NeuroDerm Ltd.

Completed

A Safety, Tolerability, and Plasma Concentration Study of Levodopa/Carbidopa Subcutaneous Solution (ND0612) in Parkinson's Disease (PD) Patients

Parkinson's Disease

Israel
Universität des Saarlandes

Completed

Choline Metabolites in People With Prostate Cancer and Those With Benign Hyperplasia

Benign Prostatic Hyperplasia | Primary Prostate Urothelial Cancer

Germany
University of Maryland, Baltimore

Active, not recruiting

Belantamab Mafodotin, Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States

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