Search clinical trials for: Morphine equivalent dose

Total 23315 results

Southern Illinois University

Completed

Exparel and Marcaine for Pain Management in Thoracoscopic Lobectomy Patients (BEMP)

Non Small Cell Lung Cancer | Lung Cancer Stage 1

United States
Pfizer

Completed

Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)

Healthy

Canada
QRxPharma Inc.

Completed

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

Postoperative Pain

United States
Tongji Hospital
Xinxiang Central Hospital

Not yet recruiting

Effect of Equivalent Dose Sufentanil and Afentanil in Bronchoscopic Treatment (EOEDSAAIBT)

Effect of Drug

China
Tongji Hospital

Not yet recruiting

Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study

Postoperative Analgesia
Pharma Nueva

Not yet recruiting

Multiple Dose, Bioequivalence Study of Generic Alfuzosin Hydrochloride 10 mg Prolonged-release Tablets Under Fed Conditions (BE24-005)

Healthy Vollunteer
United States Naval Medical Center, Portsmouth

Not yet recruiting

Liposomal Bupivacaine vs Bupivacaine With Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies

Breast Cancer
International Bio service

Not yet recruiting

The Bioequivalence Study of Fixed-dose Combination of Vildagliptin and Metformin HCI 50/1000 mg FCT Under Fed Conditions

Healthy Volunteer
Boehringer Ingelheim

Recruiting

A Study to Test How Well Multiple Doses of BI 765423 Are Tolerated by Healthy Men

Healthy

Belgium
International Bio service

Not yet recruiting

Bioequivalence Study of Generic Leflunomide 20 mg Film-coated Tablets and Reference Product Under Fasting Conditions

Healthy Volunteer
Jessa Hospital

Recruiting

High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.

Analgesia | Surgery | Post Operative Pain | Cardiac Disease

Belgium
NewAmsterdam Pharma

Recruiting

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies (TANDEM)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | High Cholesterol | ASCVD

United States
Beni-Suef University

Recruiting

Dexmedetomidine Plus Low Dose Morphine Versus Standard Dose of Morphine in PCA in Children .

Children | Dexmedetomidine | Morphine | PCA

Egypt
Jan Kochanowski University

Recruiting

Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure

Heart Failure

Poland
University of Iowa

Recruiting

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

Delirium | Spinal Fusion | Pain, Back | Thoracolumbar Interfascial Plane Block

United States
Centre Hospitalier Intercommunal Creteil

Recruiting

Pharmacokinetics-pharmacodynamics of Morphine With or Without Midazolam Administered by Continuous Infusion in Neonatal Intensive Care

Sedation Complication | Mechanical Ventilation in Neonates

France
Sohag University

Recruiting

Postoperative Pain Control by Use of Many Drugs in Small Doses Intrathecally

Post Operative Pain

Egypt
Novartis Pharmaceuticals

Recruiting

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

Glioblastoma

Spain, Switzerland, France, Portugal, United States
Assistance Publique Hopitaux De Marseille

Recruiting

Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient (KLOE)

Traumatic Injury

France
Fujian Cancer Hospital

Not yet recruiting

IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

Cancer Pain

China
Jennifer Holder-Murray
Berry Consultants

Recruiting

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

Perioperative Optimization

United States
Alaxia SAS

Recruiting

Dose Finding Study of STR-324

Pain, Acute

Netherlands
Kiyuk Chang, MD,PhD

Recruiting

Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI (ROSUZET-AMI)

Myocardial Infarction | Statin Adverse Reaction | HMG-CoA Reductase Inhibitor Toxicity

Korea, Republic of
Leiden University Medical Center
Merck Sharp & Dohme LLC

Recruiting

Impact of Deep Versus Standard Muscle Relaxation on Intra-operative Safety (EURORELAX)

Surgery--Complications | Neuromuscular Blockade | Anesthesia Complication | Rocuronium | Neuromuscular Blocking Agents | Anesthetics

Spain, Netherlands, France, Italy
BeiGene

Recruiting

Study of BGB-A425 and LBL-007 in Combination With Tislelizumab in Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2

Australia, United States, Spain, France, Italy, Korea, Republic of, Poland
Taiho Oncology, Inc.

Active, not recruiting

A Study of TAS-120 in Patients With Metastatic Breast Cancer

Metastatic Breast Cancer | FGFR2 Amplification | FGFR 1 High Amplification

Italy, United States, France, United Kingdom, Spain, Portugal, Canada
Helsinn Healthcare SA

Active, not recruiting

Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk) (CINV)

Chemotherapy-induced Nausea and Vomiting

Spain, Germany, Switzerland, China, Czechia, United Kingdom, Greece
Haisco Pharmaceutical Group Co., Ltd.

Completed

Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease（NAFLD）

Hypercholesterolemia

China
Mayo Clinic

Completed

Intrathecal Opioids for Colorectal Resection

Pain, Postoperative | Colorectal Surgery | Analgesic, Opioid

United States
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Completed

The Safety and Tolerability of WS016 in Healthy Chinese Volunteers

Hyperkalemia

China
Actavis Inc.

Completed

Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fasting Conditions

Healthy

Canada
Xcovery Holdings, Inc.

Completed

A Single Dose BE Study of X-396 in Healthy Volunteers Under Fasted Conditions

Bioequivalency

United States
Istanbul University

Completed

Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations

Pain, Postoperative | Analgesia | Anesthesia

Turkey
Pharmtechnology LLC
Altasciences Company Inc.

Completed

Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions

Bioequivalence

Canada
Bayer

Completed

A Study to Learn More About the Safety and the Blood Level of BAY1747846 Given as Injection Into the Vein at Increasing Single Doses in Chinese Healthy Male Participants

Healthy Volunteers | Contrast Enhancement in Magnetic Resonance Imaging

China
Bayer

Completed

A Study to Learn More About the Safety and the Level of BAY 1747846 in Body Given as Injection Into the Vein at Increasing Single Doses in Japanese Healthy Male Participants

Healthy Volunteers | Contrast Enhancement in Magnetic Resonance Imaging

Japan
London School of Hygiene and Tropical Medicine
University College, London; Bill and Melinda Gates Foundation; Wellcome Trust; KEMRI-Wellcome... and other collaborators

Active, not recruiting

The Effect of Fractional Doses of Pneumococcal Conjugate Vaccines on Immunogenicity and Carriage in Kenyan Infants (FPCV)

Pneumococcal Infection | Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Kenya
Bristol-Myers Squibb

Completed

A Study to Assess the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Healthy Participants

United States
University of Aarhus
Aarhus University Hospital; Central Denmark Region

Terminated

Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED (KetMo)

Acute Pain | Opioid Use

Denmark
Pfizer

Completed

Acute Treatment Trial in Adult Subjects With Migraines

Migraine

United States
Columbia University

Suspended

2 Dose Neuraxial Morphine for Prevention of PDPH

Postdural Puncture Headache

United States
Samik Pharmaceutical Co. Ltd.

Completed

A Clinical Trial to Evaluate the Pharmacokinetics and Safety of SIPS-2209-1 in Healthy Korean Volunteers

Healthy

Korea, Republic of
Antev Ltd.

Completed

Teverelix Evaluated in Advanced Prostate Cancer (TEACh)

Prostatic Adenoma

Lithuania
Rhodes Pharmaceuticals, L.P.

Completed

A Flexible-Dose Titration Study of Aptensio XR in Children Ages 4 to Under 6 Years Diagnosed With ADHD (EF003)

Attention Deficit Disorder With Hyperactivity

United States
Prestige Biopharma Limited

Completed

A Study to Demonstrate the Equivalent Pharmacokinetic Properties of a Single Intravenous Dose of HD201 and EU-Herceptin® and US-Herceptin® in Healthy Male Subjects (TROIKA-1)

Healthy Volunteers

Australia
University Children's Hospital Basel
Permamed AG, Switzerland; Galvita AG, Switzerland

Completed

Bioequivalence of a Single-dose of 12 mg IVERMECTIN as Orally Disintegrating Mini Tablets Versus a Single-dose of 12 mg Regular IVERMECTIN Tablets in Healthy Adults Under Fasting Conditions (CHILD-IVITAB)

Bioequivalence

Switzerland
Nantes University Hospital

Terminated

Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia (KETAMORPH)

Pain Management

France
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Healthy Participants

United States
Assistance Publique - Hôpitaux de Paris

Completed

Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS) (OPIDYS)

Acute Respiratory Failure

France
Regulus Therapeutics Inc.

Completed

A Study of RGLS8429 in Healthy Volunteers

Healthy Volunteers

United States

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