Search clinical trials for: Mucosal Lining Fluid

Total 4018 results

Imperial College London

Completed

Development of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen

Asthma | Latent Tuberculosis | Allergic Rhinitis

United Kingdom
Radboud University Medical Center

Completed

Mucosal Immunity Against SARS-CoV-2 Infection in COVID-19 Patients (MuCo)

SARS-CoV-2 Infection

Netherlands
Imperial College Healthcare NHS Trust

Unknown

Nasal, Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory Diseases (RESPI-SAM)

Healthy | Asthma | Tuberculosis | COPD | Sarcoidosis | IPF

United Kingdom
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use

Cigarette Smoking-Related Carcinoma

United States
Southeast University, China

Recruiting

Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients

Ventilator-associated Pneumonia | Multidrug Resistant Bacterial Infection | Polymyxin B | Pharmacogenomic Drug Interaction

China
Franciscus Gasthuis
Erasmus Medical Center; TNO

Recruiting

Phenotyping and Classifying Asthma Exacerbations (ExCluSieF)

Asthma Attack

Netherlands
The University of Queensland
Chinese University of Hong Kong; University of Malaya; The Alfred; Centre Hospitalier... and other collaborators

Recruiting

PNEUmonia DOSing in Critically Ill Patients (PNEUDOS) (PNEUDOS)

Pneumonia

Hong Kong, France, Belgium, Australia, Malaysia
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...
Innovative Medicines Initiative; Universitätsklinikum Köln

Withdrawn

Safety and PK Trial Evaluating the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Minocin IV

Normal Healthy Volunteers

Austria
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
University of Jena
Medical University Innsbruck

Completed

Effects of Kalydeco on Upper Airway and Paranasal Sinus Inflammation Measured by Nasal Lavage and on Symptoms (KPNSI)

Inflammatory Changes in Epithelial Lining Fluid Sampled Non-invasively by Nasal Lavage in CF Patients With G551D Receiving Kalydeco

Germany
Endo Pharmaceuticals

Completed

Safety and Pharmacokinetics of Vasopressin in Healthy Volunteers

Healthy Volunteer Safety Study

United States
Baxalta now part of Shire
Arriva Pharmaceuticals, Inc.

Completed

Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency

Alpha1-antitrypsin Deficiency

United States
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
Nazarbayev University Medical Center
Eurasia Invest Ltd.; Ministry of Education and Science, Republic of Kazakhstan

Completed

The Sublimated Mare Milk Supplement's Effect on Gut Mucosal Lining After Antibiotics

Acute Bronchitis

Kazakhstan
Ludwig-Maximilians - University of Munich

Completed

Development a Method to Extract Antibiotic Concentration From Interstitial Lung and Epithelial Lining Fluid. (ALF)

Lung Transplantation

Germany
Allecra

Completed

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Healthy Subjects

United Kingdom
Venatorx Pharmaceuticals, Inc.
National Institutes of Health (NIH)

Completed

Safety and Pharmacokinetics of VNRX-5133 in the Epithelial Lining Fluid of Healthy Adult Subjects

Healthy Subjects

United States
Fraunhofer-Institute of Toxicology and Experimental...
AstraZeneca

Completed

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Healthy

Germany
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy

Metastatic Colorectal Cancer | Squamous Cell Carcinoma of Head and Neck (SCCHN)

France, Belgium, Spain, Germany, Italy, Canada, United States
Entasis Therapeutics
Clinartis

Completed

Study to Determine and Compare Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam in Healthy Subjects

Healthy

United States
Pfizer

Completed

Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma

Healthy

United Kingdom
University of Aarhus
Aarhus University Hospital

Terminated

Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration

Invasive Aspergillosis

Denmark
MerLion Pharmaceuticals GmbH

Completed

Pharmacokinetic Profile in Plasma and Epithelial Lining Fluid of Finafloxacin

Safety and Tolerability

United States
Cliniques universitaires Saint-Luc- Université...

Unknown

Impaired Secretory IgA and Mucosal Immunity in Cystic Fibrosis (Forton2015)

Cystic Fibrosis

Belgium
Keith A. Rodvold
Pulmonary Associates, PA

Completed

Doripenem Intrapulmonary Pharmacokinetics in Healthy Adult Subjects

Healthy

United States
Hacettepe University

Completed

Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry Mouth

Sjogren's Syndrome | Xerostomia

Turkey
University Hospital Tuebingen

Terminated

Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion

Pneumonia | Bacteremia

Germany
HealthPartners Institute
United States Department of Defense; Uniformed Services University of the Health...

Not yet recruiting

Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age (INI-CSF-MA)

Healthy

United States
True You Weight Loss

Not yet recruiting

Fundus Ablation Registry (Gastric Fundus Mucosal Ablation for Weight Loss)

Obesity

United States
Peking University Cancer Hospital & Institute

Not yet recruiting

A Trial of AK104 or AK112 in Combination With Axitinib in Patients With Metastatic Mucosal Melanoma

Melanoma | Metastatic Melanoma | Mucosal Melanoma

China
Hospices Civils de Lyon

Not yet recruiting

Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy

Fluid Overload | Critically Ill | Continuous Renal Replacement Therapy | Fluid Removal

France
Tanta University

Recruiting

Trendelenburg Maneuver Versus Passive Leg Raising Test for Fluid Responsiveness in High-Risk Surgical Patients

Passive Leg Raising | High-Risk Surgical Patients | Trendelenburg Maneuver

Egypt
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Echocardiographic Measurement of Myocardial Work (MYOLOAD)

Intensive Care Unit Syndrome | Cardiovascular Physiological Phenomena

France
True You Weight Loss

Recruiting

Ablation Registry (Combined Gastric Mucosal Ablation With Endoscopic Sleeve Gastroplasty for Weight Loss)

Obesity

United States
Top Health S.A.P.I DE C.V.
CLINICAL RESEARCH PS MEXICO

Not yet recruiting

Study to Evaluate the Effectivity and Safety of BIOSCAFF®H Compared to DuraGen®, in Patients Undergoing Dural Repair

Cerebrospinal Fluid Leakage
Lenox Hill Hospital

Recruiting

Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning (TREND-US)

Shock | Fluid Overload | Cardiac Output, Low

United States
Centre Hospitalier Universitaire Dijon

Not yet recruiting

Ultrasound and Clinical Approach for the Dynamic Assessment of Fluid Tolerance in the Intensive Care Unit (FLUID-REACT)

Volume Expander

France
Arizona State University

Not yet recruiting

Rehydration Efficiency During Ad-libitum Fluid Intake (LIV-D2O)

Dehydration

United States
Centre hospitalier de l'Université de Montréal...

Not yet recruiting

UltraSound Evaluation of Fluid tOleRanCE for Acute Kidney Injury (USE-the-FORCE)

Acute Kidney Injury

Canada
Rhaeos, Inc.

Not yet recruiting

Assessment of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device in Asymptomatic Patients

Hydrocephalus
Nazmy Edward Seif

Recruiting

Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy

Renal Impairment | Prostate Cancer | Surgery | Bladder Cancer | Renal Injury, Acute

Egypt
Rhaeos, Inc.

Not yet recruiting

Assessment of Flow in Cerebrospinal Fluid Shunts With a Second Generation Wireless Thermal Anisotropy Measurement Device

Hydrocephalus
Pramand LLC

Not yet recruiting

CraniSeal Post Approval Study

Leak, Cerebrospinal Fluid
Seoul National University Bundang Hospital
Samjin Pharmaceutical Co., Ltd.

Recruiting

Clopidogrel Versus Cilostazol on Vessels

Atherosclerosis | Type 2 Diabetes

Korea, Republic of
The Hong Kong Polytechnic University

Recruiting

Vulnerability Markers for Depression

Healthy | Major Depressive Disorder | Major Depressive Disorder Remission

Hong Kong
Dalia Nasser Mohamed

Recruiting

Clinical Value of the Developed Scoring Systems for Predicting Spontaneous Bacterial Peritonitis in Cirrhotic Ascites

Cirrhotic Ascitic Patients

Egypt
Federal State Budgetary Institution, V. A. Almazov...

Recruiting

Prospective, Post-registration, Interventional, Randomized, in Parallel Groups, Multicenter Eurasian Clinical Study of DERIVO®/DERIVO® Mini Aneurysm Embolization Device, Europe-Asia

Intracranial Aneurysm

Russian Federation
AquaPass Medical Ltd.

Not yet recruiting

Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry (REFORM-HF II)

Edema | Chronic Heart Failure | Acute Decompensated Heart Failure | Fluid Overload
Universiti Sains Malaysia

Recruiting

Electrolyte Balance Effects of Sterofundin Versus Normal Saline in Diabetic Ketoacidosis

Treatment Diabetic Ketoacidosis, Electrolyte Balance Effects

Malaysia

Search clinical trials for: Mucosal Lining Fluid

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