Search clinical trials for: NAD dependent sirtuin enzymes

Total 52557 results

National Heart, Lung, and Blood Institute (NHLBI)

Terminated

The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

Heart Failure

United States
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Tampere University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Recruiting

Shortening Duration of Antiarrhythmic Medication for SVT in Infants

Supraventricular Tachycardia

Finland
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
Charles University, Czech Republic

Completed

Propafenone Versus Amiodarone in Septic Shock (PRASE)

Septic Shock | Supraventricular Arrhythmia

Czechia
Assiut University

Unknown

Management of Supraventricular Tachycardia of Children

Supraventricular Tachycardia
Hannover Medical School

Terminated

Pharmacovigilance in Gerontopsychiatric Patients (GAP)

Depression | Schizophrenia | Anxiety Disorders | Dementia | Psychosomatic Disorders

Germany
Uppsala University Hospital
Swedish Heart Lung Foundation

Unknown

Catheter Ablation Compared With Pharmacological Therapy for Atrial Fibrillation (CAPTAF Trial) (CAPTAF)

Quality of Life | Atrial Fibrillation

Sweden
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals

Marijuana Abuse

United States
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of Bupropion in Treating Marijuana Dependent Individuals

Substance-Related Disorders | Marijuana Abuse

United States
National Institute on Drug Abuse (NIDA)

Completed

Substance Dependent Teens - Impact of Treating Depression Study 1 - 1

Substance-Related Disorders | Alcohol-Related Disorders | Marijuana Abuse

United States
Tehran University of Medical Sciences

Unknown

The Effects of Omega 3 and Vitamin E Supplementation on the Serum Antioxidant Enzymes and Gene Expressions of PGC-1a, h TERT, FOXOs and SIRTs in CAD Patients

Coronary Artery Disease

Iran, Islamic Republic of
Orexigen Therapeutics, Inc

Completed

A Study of Naltrexone SR/ Bupropion SR in Overweight and Obese Subjects Who Are Nicotine-Dependent

Obesity | Overweight | Nicotine Dependence

United States
Memorial Sloan Kettering Cancer Center
TransThera Sciences

Recruiting

A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

Prostate Cancer

United States
Institut National de la Santé Et de la Recherche...

Recruiting

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain (APEDOC)

Stroke

France
Qian Qin
Janssen, LP; UT Southwestern Comprehensive Cancer Center

Not yet recruiting

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations (HARMONY)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
Nordsjaellands Hospital

Recruiting

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Colles' Fracture | Fracture Dislocation | Distal Radius Fractures | Lidocaine | Ropivacaine | Closed Reduction of Fracture and Application of Plaster Cast

Denmark
Mayo Clinic

Recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Amany Ahmed Eissa

Recruiting

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.

Erector Spinae Plane Block | Bariatric Surgery | Super Obese Patients

Egypt
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

Cognitive Impairment | Cannabis Use | Impaired Driving

United States
Mayo Clinic

Recruiting

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Preeclampsia

United States
Nantes University Hospital

Recruiting

Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation (EDearly AF)

Atrial Fibrillation

France
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study) (TANDEM)

Healthy | Overweight and Obesity

United States
Yuri Matusov
Mallinckrodt

Not yet recruiting

Inhaled Nitric Oxide for ARDS-related Pulmonary Hypertension

Pulmonary Hypertension | Acute Respiratory Distress Syndrome

United States
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

Methamphetamine-dependence | Methamphetamine Abuse
Post Graduate Institute of Medical Education and...

Recruiting

A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis (PICA)

Allergic Bronchopulmonary Aspergillosis

India
AstraZeneca

Recruiting

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents (EvoPAR-PR01)

Metastatic Castration-Sensitive Prostate Cancer

United States, Canada, Spain, United Kingdom, Italy, Australia, Korea, Republic of, Belgium, Germany, Japan, Peru, France, China, India, Taiwan, Thailand, Austria, Brazil, Turkey, Malaysia, Finland, Netherlands, Chile, Hungary, Poland, Sw...
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Dalpiciclib Isethionate Tablets Combined With Abiraterone Acetate Tablets (I) and Prednisone Tablets (AA-P) Versus Placebo Combined With AA-P in Treatment of High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)

High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)
University Hospital Padova

Recruiting

Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn (WHYSKI)

Hypertension | Essential Hypertension | Hyperaldosteronism | Aldosteronism | Conn Adenoma | Aldosterone Disorder | Aldosterone-producing Adenoma | Bilateral Adrenal Hyperplasia

Italy
Instituto de Investigación Sanitaria de la Fundación...

Recruiting

Hemodynamic and Functional Characteristics of the Cerebral Circulation in Obesity (HemOB)

Cerebral Arterial Diseases

Spain
University of Southern California
National Cancer Institute (NCI)

Recruiting

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myelodysplastic Syndrome | Clonal Cytopenia of Undetermined Significance

United States
CMC Ambroise Paré

Recruiting

WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release (WALAB)

Carpal Tunnel Syndrome

France
University Hospital, Montpellier
National and Kapodistrian University of Athens; University of Manchester; University... and other collaborators

Not yet recruiting

Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing (SynAIR-G)

Allergy | Asthma in Children

France
Nicox Ophthalmics, Inc.

Recruiting

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution (Whistler)

Open Angle Glaucoma

United States
Lebanese University
Hospital Saydet Zgharta University Medical Center

Recruiting

LUSZ Treatment Efficacy in Hospitalized COVID-19 Patients (LUSZ_AVIST)

COVID-19 | Hospitalized COVID-19 Patients

Lebanon
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Age-dependent Effects of Smoked and Oral Delta-9-THC (SAGE)

Pain | Abuse, Drug | Intoxication; Cannabinoids
Anabio R&D
Thai Binh University of Medicine and Pharmacy

Recruiting

LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media

Upper Respiratory Tract Infections

Vietnam
Ting YANG
Novlead Inc.

Recruiting

A Mechanistic Study of Inhaled Nitric Oxide in COPD

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

China
Louisiana State University Health Sciences Center...
Tulane University; Pennington Biomedical Research Center; Ochsner Health System

Recruiting

Anti-obesity Pharmacotherapy and Inflammation

Obesity

United States
Novlead Inc.

Recruiting

A Real-world Study of Nitric Oxide Generator and Delivery System

Pulmonary Hypertension of Newborn

China
Lucie Heinzerling

Recruiting

Treatment of Immune-related Adverse Events Refractory to Standard Therapy and Associated Changes in Immunophenotype (PRIA)

Immune-related Adverse Event

Germany
Universiti Kebangsaan Malaysia Medical Centre

Not yet recruiting

Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting

Glaucoma | Cataract

Malaysia
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Children's Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | Unresectable Osteosarcoma | Resectable Osteosarcoma
Overseas Pharmaceuticals, Ltd.
Guangzhou Health Start Pharmaceutical Techology Co.,Ltd

Not yet recruiting

An Comparative Pharmacokinetic Study of Amlodipine Besylate Controlled-release Tablets,China in Normal, Healthy, Adult, Human Subjects Under Fasting Conditions

Hypertension

China
Sohag University

Not yet recruiting

Cyclosporine Adverse Outcomes in Steroid Dependent and Frequent Relapsing Nephrotic Syndrome in Children;Single Center Study

Steroid Dependent and Frequent Relapsing Nephrotic Syndrome

Egypt
Shanghai Zhongshan Hospital

Recruiting

Consistency of Electrical Cardiometry and Pulmonary Artery Catheter

Pulmonary Arterial Hypertension | Right Ventricular Dysfunction

China
Hippocration General Hospital
Win Medica; Pharmassist Ltd

Recruiting

Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia (FLECA-ED)

Atrial Fibrillation Paroxysmal | Coronary Artery Disease Without Residual Ischemia

Greece
Icahn School of Medicine at Mount Sinai

Recruiting

Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer

Pancreatic Cancer

United States
University of Nottingham

Recruiting

Asthma: Phenotyping Exacerbations 3 (APEX3)

Asthma Attack

United Kingdom

Search clinical trials for: NAD dependent sirtuin enzymes

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