Search clinical trials for: Non Severe Fibrosis

Total 65090 results

Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
University Hospital, Lille
Ministry of Health, France

Recruiting

A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients (NASHSURG)

Obesity | Cirrhosis | Surgery | NASH - Nonalcoholic Steatohepatitis

France
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Sagimet Biosciences Inc.

Completed

A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Cirrhosis | Hepatic Impairment | Non-alcoholic Steatohepatitis

United States, Hungary
Sound Pharmaceuticals, Incorporated

Enrolling by invitation

SPI-1005 Treatment in Severe COVID-19 Patients

Coronavirus Infection | Covid19 | Corona Virus Infection | Coronavirus

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Terminated

A Comparative Study of Pravastatin vs Placebo as Primary Prevention of Severe Subcutaneous Breast Fibrosis in Hyper-radiosensitive Identified Patients With Breast Cancer (PRAVAPREV-01)

Breast Cancer

Monaco, France
AbbVie

Completed

A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Ulcerative Colitis (U-Accomplish)

Ulcerative Colitis (UC)

United States, Argentina, Australia, Austria, Belgium, Bosnia and Herzegovina, Brazil, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic... and more
Histogen

Completed

Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension (ENCORE-PH)

Cirrhosis | Portal Hypertension | Non-alcoholic Steatohepatitis

United States, Germany, Spain
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); N... and other collaborators

Terminated

Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency (CBZ)

Liver Cirrhosis | Alpha-1-antitrypsin Deficiency

United States
University Hospital, Clermont-Ferrand
Merck Sharp & Dohme LLC

Completed

Study to Investigate the Efficacy of Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in Treatment-Naïve, HCV GT1b-Infected Patients, With Non-severe Fibrosis (STREAGER)

Chronic HCV Infection

France
Institute of Liver and Biliary Sciences, India

Withdrawn

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

Cirrhosis

India
King's College London
Pfizer

Unknown

An Observational Cohort Study Evaluating Fatty Liver Disease and Liver Fibrosis in Moderate to Severe Psoriasis (CORE)

Fatty Liver | Non-alcoholic Fatty Liver Disease | Liver Fibrosis | Psoriasis Chronic

United Kingdom
First Affiliated Hospital, Sun Yat-Sen University

Completed

Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion

Intrauterine Adhesion

China
Scripps Health
Depomed

Unknown

IM Ketorolac vs Cambia for the Acute Treatment of Severe Migraine

Migraine Headache

United States
National Human Genome Research Institute (NHGRI)

Terminated

Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome

Pulmonary Fibrosis | Metabolic Disease | Oculocutaneous Albinism | Hermansky-Pudlak Syndrome (HPS) | Platelet Storage Pool Deficiency

United States
NHS Lothian

Completed

Is Regular Chest Physiotherapy an Effective Treatment in Severe, Non Cystic Fibrosis Bronchiectasis?

Bronchiectasis

United Kingdom
Symbollon Pharmaceuticals

Unknown

Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain

Pain | Fibrocystic Disease of Breast | Fibrocystic Changes of Breast | Fibrocystic Mastopathy

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
Peking Union Medical College Hospital

Not yet recruiting

A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag

Aplastic Anemia

China
AstraZeneca

Not yet recruiting

A Non-interventional, Prospective Study With Benralizumab (AIR POWER)

Asthma, Bronchial
89bio, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

United States
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis (BioMol-MA)

Non-Tuberculous Mycobacterial Pneumonia | Cystic Fibrosis Lung

Italy
Beijing 302 Hospital
LanZhou University; Shengjing Hospital; Qianfoshan Hospital; The Affiliated Hospital... and other collaborators

Recruiting

Noninvasive Diagnosis Model for High-risk Varices in Cirrhosis (NID-HRV)

Liver Cirrhosis | Varices

China
University of Groningen
Lentis Psychiatric Institute; GGZ Friesland; Stichting Cosis

Not yet recruiting

Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI) (HEADDSET+)

Severe Mental Illness

Netherlands
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico
Post Graduate Institute of Medical Education and...

Not yet recruiting

MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin (SHIELD)

Non-Alcoholic Fatty Liver Disease | Hepatic Steato-Fibrosis

India
Centre Hospitalier Intercommunal Creteil
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis (ANTEIPA)

Bronchiectasis

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Sintilimab Plus FOLFIRI as Salvage Therapy for Patients With Advanced Gastric Cancer

Unresectable/Metastatic Gastric Cancer

China
University Hospital, Montpellier
On-call medical home (MMG) Clermont-Hérault

Not yet recruiting

Screening for Chronic Liver Diseases in General Population (HEPGEN)

Fibrosis, Liver

France
Assiut University

Not yet recruiting

Procalcitonin as a Marker of Severity of Non-cystic Fibrosis Bronchiectasis in Children

Non-cystic Fibrosis Bronchiectasis
Sir Ganga Ram Hospital

Recruiting

Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot Study

Hepatic Encephalopathy

India
Avalyn Pharma Inc.
DevPro Biopharma

Recruiting

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary Fibrosis

United States
Leuko Labs, Inc.

Not yet recruiting

Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe Neutropenia (PC002)

Multiple Myeloma | Diffuse Large B Cell Lymphoma
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Optimization of Routine Obstetric and Neonatal Care in the Management of Severe Perinatal Asphyxia in Term or Near-term Newborns: Analysis of Sub-optimal Care (OptiNeoCare)

Perinatal Asphyxia
First Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Noninvasive Prediction of Portal Hypertension in Cirrhosis Using Sound Touch Viscoelastography

Cirrhosis | Portal Hypertension

China
89bio, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

United States
University of Bologna

Recruiting

Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis (KETONASH)

Obesity | NAFLD | Liver Fibrosis | NASH

Italy
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China
The Second Affiliated Hospital of Chongqing Medical...

Recruiting

Safety and Effectiveness of Sulfasalazine in the Treatment of Liver Fibrosis/Cirrhosis.

Fibrosis, Liver | Cirrhosis, Liver

China
Aristotle University Of Thessaloniki
University Hospital of Crete; University Hospital of Patras; Pulmonary Clinic... and other collaborators

Recruiting

BenRalizumab Effect on Airway Remodeling in Severe asTHma (BREATH)

Airway Remodeling | Asthma; Eosinophilic

Greece
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis

Bronchiectasis

United Kingdom, Japan, United States, Israel, Canada
University Hospital, Rouen

Not yet recruiting

Nebulized Fentanyl in Healthy Volunteers (AEROfen)

Emergencies | Analgesia

France
EMS

Not yet recruiting

Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. (SIERRA)

Allergic Rhinitis
Kodiak Sciences Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW2)

Non-proliferative Diabetic Retinopathy

United States, Puerto Rico
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies

Patients With Nonmyeloid Malignancies Receiving Antineoplastic Therapy Based on Chemotherapy Regimens at Moderate to High Febrile Neutropenia (FN) Risk

China
SHINKEI Therapeutics, Inc
Duke Clinical Research Institute

Not yet recruiting

Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301) in Patients With Severe Traumatic Brain Injury (TBI).

Traumatic Brain Injury
University of North Carolina, Chapel Hill
Cystic Fibrosis Foundation

Recruiting

Hypertonic Saline in NCFB

Bronchiectasis | Non-cystic Fibrosis Bronchiectasis

United States
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Chile, United Kingdom, United States, Canada, Turkey, Israel, Korea, Republic of
Boehringer Ingelheim

Not yet recruiting

A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood

Idiopathic Pulmonary Fibrosis

Search clinical trials for: Non Severe Fibrosis

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