Search clinical trials for: Non-Small-Cell Lung Cancer (NSCLC), First-in-human,

Total 346617 results

Pfizer

Completed

A Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Oral Doses Of PF-03716539 In Healthy Adult Subjects

Healthy Volunteers

Belgium
GlaxoSmithKline

Completed

A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease

Alzheimer's Disease

Australia, Sweden, Norway
Vivheart s.r.l.

Recruiting

EasyCrossTM Device-Self-centering Catheter (VIV-FIH)

Transcatheter Aortic Valve Replacement (TAVR)

Italy
InFlectis BioScience
Assistance Publique Hopitaux De Marseille; Qualissima; Eurofins Optimed; Stragen...

Completed

A Combined SAD and MAD Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of IFB-088

Healthy Volunteers

France
AstraZeneca

Recruiting

A Phase I/IIa Study of AZD8205 Given Alone or in Combination With Anticancer Drugs, in Participants With Advanced or Metastatic Solid Malignancies

Breast Cancer | Ovarian Cancer | Endometrial Cancer | Biliary Tract Carcinoma

United States, Australia, Spain, United Kingdom, Korea, Republic of, Canada, Italy, Poland, Belgium, China, Japan, Taiwan, Thailand, Hungary, Netherlands
Pfizer

Completed

Evaluation Of Safety, Tolerability And Pharmacokinetics Of Single And Multiple Doses Of Compound PF-06823859

Healthy

United States
AstraZeneca
Parexel

Completed

A Study to Evaluate the Safety and Pharmacokinetics With MEDI8367 Administered in Healthy Subjects, and in Subjects With Chronic Kidney Disease

Chronic Kidney Disease

United States
Regeneron Pharmaceuticals

Recruiting

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers (COMBINE-EGFR-1)

Advanced Solid Tumors

United States, Spain, Turkey, France
Pfizer

Terminated

A Study In Healthy Subjects Of Single Doses of PF-05230901 Injected Under The Skin

Cachexia

United States
German Cancer Research Center
University Hospital Heidelberg; National Center for Tumor Diseases, Heidelberg

Completed

POSITIVE - Study (Part III) Heidelberg (POSITIVE)

Advanced NSCLC | First Line Treatment

Germany
Handok Inc.

Completed

A Dose-Block Randomized, Placebo Controlled (Double-blind), Active Controlled(Open-label), Dose-escalation Study

Healthy Volunteers

Korea, Republic of
Shanghai EpimAb Biotherapeutics Co., Ltd.
Covance

Recruiting

A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors

Neoplasms | Neoplasm Metastasis | Non-Small-Cell Lung Cancer

United States, China
Enterome

Completed

A Study of a FimH Blocker, EB8018, in Crohn's Disease Patients (EBFIM117)

Crohn Disease

France, Germany, Italy, Austria
University Hospital, Grenoble
Société Française d'Anesthésie et de Réanimation

Completed

eFast Diagnosis Performance in Guiding First Aid Resuscitation (eFAST Decision)

eFast Diagnosis Performance in Guiding First Aid Resuscitation and Hemostasis

France
Novartis Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose CFZ533 in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

United States, Taiwan
HiberCell, Inc.
Covance

Terminated

A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)

Clear Cell Renal Cell Carcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Colo-rectal Cancer | Transitional Cell Carcinoma of the Bladder | Other Solid Tumors

United States
Syneos Health
F-star Therapeutics, Inc.

Completed

A Multiple Ascending Dose Phase I Study of SB 9200 in Treatment Naïve Adults With Chronic Hepatitis C Infection

Hepatitis C Infection

Australia, New Zealand
Pfizer

Completed

Study of Single Ascending Doses of PF-07081532 in Healthy Adult Participants

Healthy

Belgium
Regeneron Pharmaceuticals

Completed

A Trial to Learn if REGN7999 is Safe and Well Tolerated, and How it Works in the Body of Healthy Participants

Healthy

Belgium
UCB Biopharma S.P.R.L.

Completed

A First-In-Human Study With a Single Ascending Dose of UCB7858 in Healthy Volunteers

Healthy Volunteers

United Kingdom
AstraZeneca

Completed

A Study in Healthy Volunteers to Assess the Tolerability and Blood Levels of a Single Dose of AZD7687

Healthy

United States
University of California, San Diego

Recruiting

Pharmacist Provision of Medication Abortion

Abortion in First Trimester

United States
Stanford University
Gynuity Health Projects

Terminated

Choice of Modality of Follow up for Medication Abortion

Abortion in First Trimester

United States
University Hospital of the West Indies

Completed

The Effect of Hyoscine Butyl Bromide on the First Stage of Labor in Term Pregnancies

Labor Stage, First

Jamaica
University Health Network, Toronto

Unknown

Virtual Assistant for COVID-19 PPE

COVID-19

Canada
Shandong Boan Biotechnology Co., Ltd

Recruiting

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1106 in Advanced Solid Tumors

Solid Tumors

China
GlaxoSmithKline

Completed

Investigation Of a New Oral Anti-Histamine in Healthy Male Subjects

Rhinitis, Allergic, Seasonal

United Kingdom
GlaxoSmithKline

Completed

Single and Repeat Dose First Time in Human Study for an Intranasal H1/H3 Dual Antagonist in Healthy Male Subjects

Rhinitis, Allergic, Seasonal

Germany
Tianjin Hemay Pharmaceutical Co., Ltd

Completed

A Phase I Clinical Study of Hemay808

Safety Issues

China
UCB Biopharma S.P.R.L.

Completed

A First-In-Human Study With a Single Dose UCB4019 in Healthy Volunteers

Healthy Volunteers

United Kingdom
St. Jude Children's Research Hospital
Eisai Inc.; Medicines for Malaria Venture; Global Health Innovative Technology...

Completed

First-in-Human Study of an Oral Plasmodium Falciparum Plasma Membrane Protein Inhibitor

Malaria

United States
KK Women's and Children's Hospital

Recruiting

The Use of Letrozole or Mifepristone for Pretreatment of Medical Termination of Pregnancy

Abortion in First Trimester

Singapore
Washington University School of Medicine

Completed

Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 Weeks

Abortion in First Trimester

United States
Vernalis (R&D) Ltd

Completed

Single and Multiple Ascending Dose Study of V158866 in Healthy Volunteers

First in Man Study

United Kingdom
Sydney Children's Hospitals Network

Completed

Role of Technology in Improving Asthma Management In School Staff

Asthma in Children

Australia
Ramsay Générale de Santé
European Clinical Trial Experts Network; Private hospital Parly II

Recruiting

The Human Sperm Survival Assay (HSSA) as an Internal Quality Control for the IVF Consumables (REPROTOX 2) (REPROTOX 2)

in Vitro Fertilization | Human Sperm Survival Assay | Embryotoxicity

France
Lepu Medical Technology (Beijing) Co., Ltd.

Unknown

NeoVas Bioresorbable Coronary Scaffold First-in-Man Study

Coronary Artery Disease

China
University of Cape Town
Karolinska Institutet; University of California, San Francisco; Grand Challenges...

Recruiting

Telemedicine for First Trimester Abortion in South Africa

Abortion in First Trimester

South Africa
Hoffmann-La Roche

Completed

RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors

Solid Tumor, Unspecified, Adult

United States
Guy's and St Thomas' NHS Foundation Trust
King's College London

Not yet recruiting

Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET

Cancer | Diagnosis | Resistant Cancer | Response, Acute Phase
BrodenBio Co., Ltd.

Recruiting

A Phase 1 Study of BB3008 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

China
Peptomyc S.L.

Terminated

Phase 1/2 Study to Evaluate Safety, PK and Efficacy of the MYC-Inhibitor OMO-103 in Solid Tumours (MYCure)

Pancreatic Cancer | Advanced Solid Tumors | CRC

Spain
Red Queen Therapeutics, Inc.
PPD

Completed

Clinical Trial to Evaluate the Safety of RQ-01 in SARS-CoV-2 Positive Subjects

COVID-19 | Infectious Disease | SARS CoV 2 Infection | Symptomatic COVID-19 Infection Laboratory-Confirmed

United States
GlaxoSmithKline

Completed

Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors

Neoplasms | Cancer

Australia, United States, Netherlands
Reata, a wholly owned subsidiary of Biogen
AbbVie

Completed

RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVER (DISCOVER)

Metastatic or Incurable Non-small Cell Lung Cancer | Relapsed, Refractory Melanoma

United States
Merus N.V.
Incyte Corporation

Recruiting

A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies

Advanced Cancer | Solid Tumor, Adult | B-cell Lymphoma, Adult

United States, Spain, Belgium, Netherlands
HaEmek Medical Center, Israel

Completed

Intrapartum Hydration

Labor Stage, First | Labor Stage, Second

Israel
Anwita Biosciences
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 1 First-in-human Study of JS014

Lymphoma | Solid Tumor, Adult | Neoplasm Malignant | Neoplasm, Experimental

Taiwan
Heptares Therapeutics Limited

Completed

A Study in Healthy Subjects to Assess the Safety, Tolerability, PK and PD of HTL0030310

Healthy

United Kingdom
UCB Celltech
Parexel

Completed

A First-In-Human Study With a Single Dose UCB7665 in Healthy Volunteers

Healthy

United Kingdom

Search clinical trials for: Non-Small-Cell Lung Cancer (NSCLC), First-in-human,

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