Search clinical trials for: Obese male subjects

Total 37755 results

Mereo BioPharma

Completed

Safety and Efficacy of BGS649 in Male Obese Subjects With Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism

United States, Italy, Spain, United Kingdom
American University of Beirut Medical Center

Completed

Effect of Food Acceptability on Appetite Hormones' Response in Normal Weight vs. Obese Male Subjects

Eating Behavior
Sanofi

Completed

Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients

Type 2 Diabetes Mellitus

Germany
Novo Nordisk A/S

Completed

Investigation on Safety, Tolerability and Pharmacokinetics of Single Doses of NNC0174-0833 in Normal Weight, Overweight to Obese But Otherwise Healthy Male Subjects

Obesity | Metabolism and Nutrition Disorder

United States
Novo Nordisk A/S

Completed

Investigate Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-0530 Alone and in Combination With Liraglutide in Overweight to Obese But Otherwise Healthy Male Subjects

Obesity | Metabolism and Nutrition Disorder

United States
GlaxoSmithKline

Completed

First Time in Human Study of Intravenous Interleukin-18 Antibody (A18110040)

Inflammatory Bowel Diseases

United Kingdom
Complexa, Inc.

Completed

PK and PD of Sequential Multiple Ascending, Repeat Doses of Oral CXA-10 in Healthy Obese Male Subjects

Acute Kidney Injury

United States
GI Dynamics
University of Malaya

Terminated

EndoBarrier® SANS™ in Over-weight or Obese Type 2 Diabetic Subjects

Obesity | Type 2 Diabetes

Malaysia
Baker Heart and Diabetes Institute

Unknown

The Effect of Moxonidine on Blood Pressure and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension

Hypertension | Abdominal Obesity

Australia
Neuraly, Inc.

Not yet recruiting

A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH

NAFLD | NASH

United States
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis

Lupus Nephritis

China
Iain Bressendorff

Not yet recruiting

The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKD (CaT50HD)

Secondary Hyperparathyroidism | End-stage Kidney Disease
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

To Compare the Efficacy and Safety of HRS9531 and Placebo in Subjects With Overweight or Obese

Overweight or Obesity

China
Ferring Pharmaceuticals

Not yet recruiting

A Phase 4, Multi-center, Open Label Trial to Evaluate Efficacy of Retreatment With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose (ABLE-42)

Bladder Cancer | CIS | Ta/T1
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction

China
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Mass Balance of [14C] SY-5007 in Healthy Adult Male Subjects in China

Healthy Subjects

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of HRS-1780 Tablets in Healthy Subjects

Chronic Kidney Disease(CKD)

China
RenJi Hospital

Recruiting

Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease

Obesity | Chronic Kidney Diseases

China
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis (KYSA-3)

Lupus Nephritis | Lupus Nephritis - WHO Class IV | Lupus Nephritis - WHO Class III

Germany
Third Affiliated Hospital of Zhengzhou University

Not yet recruiting

The Impact of Lifestyle Intervention on Weight and Fertility in Obese Males

Obesity | Weight Loss | Male Fertility | IVF-ET | Artificial Insemination
Amgen

Not yet recruiting

Evaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland China

Osteoporosis
Intelligem Therapeutics Australia Pty Ltd.

Not yet recruiting

A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease

Hyperuricemia | Hypouricemia, Renal
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux® (Cetuximab) in Healthy Adult Male Chinese Subjects

EGFR Overexpression
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in Obese Subjects .

Overweight and Obesity
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical Trial

Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis

China
RemeGen Co., Ltd.

Recruiting

Disitamab Vedotin in the Treatment With HER2- Expression, Subjects With Locally Advanced or Metastatic Castration-resistant Prostate Cancer

Castration-resistant Prostate Cancer

China
Azienda Ospedaliera Specializzata in Gastroenterologia...
Antonella Bianco; Isabella Franco

Recruiting

Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD (Obesity_AF)

Obesity | NAFLD

Italy
Daiichi Sankyo
Merck Sharp & Dohme LLC

Recruiting

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Melanoma | Cervical Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Prostate Cancer | Bladder Cancer | Advanced Solid Tumor | Endometrial Cancer | Ovarian Carcinoma | Pancreatic Carcinoma

United States, Taiwan, Japan
Shanghai Henlius Biotech

Recruiting

A Study to Compare the PK , Safety, Tolerability, and Immunogenicity of HLX13 With YERVOY in Male Subjects

Healthy Male Volunteers

China
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

Chronic Kidney Disease

United States
Dendreon

Not yet recruiting

Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T (ProvONE)

Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Pharmacokinetic and Safety Studies of HRS-7535 in Subjects With Moderate Renal Insufficiency and Healthy Subjects

Type 2 Diabetes
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of HS-20094 Evaluating Weight Loss in Obese and Overweight Chinese Subjects

Overweight and Obesity

China
Hope Medicine (Nanjing) Co., Ltd

Recruiting

A Study to Assess the Efficacy and Safety of HMI-115 in Male Subjects With Androgenetic Alopecia

Androgenetic Alopecia

China
BioCryst Pharmaceuticals

Recruiting

Dose Escalation of BCX10013 in Subjects With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

South Africa, Malaysia
Ain Shams University

Recruiting

Standard PCNL Vs Endoscopic Combined Intrarenal Surgery (ECIRS) for Complex Nephrolithiasis in Obese Patients (ECIRS)

Renal Stone

Egypt
Qidni Labs Inc.

Recruiting

Evaluating the Use of the Qidni/D Hemodialysis System by Subjects With End-Stage Renal Disease

Kidney Disease, End-Stage

Canada
Amgen

Recruiting

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

Melanoma

Italy, Spain, Czechia, Serbia, Estonia, Bosnia and Herzegovina, Portugal, Romania, Georgia, Lithuania, Malaysia, United States, Taiwan, France, Canada, Thailand, Croatia, Mexico, Germany, Philippines
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS9531 Injections in Overweight or Obese Subjects

Overweight or Obesity
Cairo University

Recruiting

Telerehabilitation for Overactive Bladder Syndrome in Obese Women

Overactive Bladder Syndrome

Egypt
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Safety and Pharmacokinetics of HRS-1780 in Healthy Subjects and Subjects With Impaired Renal Function

Chronic Kidney Disease
TiumBio Co., Ltd.

Recruiting

Study of TU7710 in Warfarin Anti-coagulated Healthy Male Subjects

Hemophilia A | Hemophilia B | Blood Coagulation Disorders

Korea, Republic of
Hadassah Medical Organization

Recruiting

The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome Transplantation

Microbial Colonization | Bacterial Vaginosis

Israel
Aurinia Pharmaceuticals Inc.
Labcorp Corporation of America Holdings, Inc

Not yet recruiting

Long-Term Voclosporin Treatment in Adolescent Subjects With Lupus Nephritis (VOCAL-EXT)

Adolescent Lupus Nephritis

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Pharmacokinetic/Pharmacokinetic and Safety Studies of SHR4640 in Subjects With Moderate Renal Insufficiency and Healthy Subjects

Hyperuricemia

China
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Study to Evaluate the Pharmacokinetics of HSK21542 in Subjects With Renal Impairment

Renal Impairment

China
Hansoh BioMedical R&D Company

Recruiting

A First in Human Study to Evaluate Safety, Tolerability, Pharmacology of HS-10390 in Healthy Subjects

Focal Segmental Glomerulosclerosis | IgA Nephropathy

China
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Lupus Nephritis | Lupus Nephritis - World Health Organization (WHO) Class III | Lupus Nephritis - WHO Class IV

United States

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