Search clinical trials for: Oral bioavailability

Total 18976 results

Pfizer

Not yet recruiting

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

Healthy Participants
Opella Healthcare Group SAS, a Sanofi Company

Not yet recruiting

Bioavailability Study of Magne-B6 New Formulation

Healthy Volunteers
Insmed Incorporated

Recruiting

A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healthy Participants (INS1007)

Healthy Participants

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With Schizophrenia

Schizophrenia

United States
Fundació Eurecat
Circe, S.L.

Not yet recruiting

Oral Bioavailability of a New Formulation of Pterostilbene Cocrystal in Comparison With Its Free Form (BIOPTERO2) (BIOPTERO2)

Biological Availability

Spain
Bristol-Myers Squibb

Recruiting

A Study to Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants

Healthy Volunteers

United States
ViiV Healthcare

Recruiting

A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants

HIV Infections

United Kingdom
Shanghai Runshi Pharmaceutical Technology Co., Ltd

Not yet recruiting

Relative Bioavailability and Food Effect of SYHA1813 Oral Solution in Healthy Participants

Healthy Participants
ATXA Therapeutics Limited
Hammersmith Medicines Research

Recruiting

Safety, Pharmacokinetics (PK) and Relative Bioavailability of NTP42:KVA4 as a Solid Oral Dose

Healthy

United Kingdom
TrippBio, Inc.

Not yet recruiting

A Relative Bioavailability Study With a Novel PanCytoVir™ Oral Suspension (100 mg/ml)

Relative Bioavailability
EpiDestiny, Inc.
Worldwide Clinical Trials

Recruiting

To Study the Oral Bioavailability of a New Combination Formation of Decitabine and Tetrahydrouridine in Healthy Males

Healthy

United States
AstraZeneca

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy Subjects and to Assess the Relative Oral Bioavailability Between Two Formulations. The Study Will Also Assess the Food Effect on the PK of AZD6793 Compared to Fasting State

Inflammatory Diseases

United Kingdom
Central Hospital, Nancy, France
Fresenius Kabi; Société Francophone Nutrition Clinique et Métabolisme; FIlière...

Recruiting

Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome (GRAAL)

Infection, Bacterial | Short Bowel Syndrome

France
Northwestern University
National Cancer Institute (NCI)

Recruiting

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Myeloproliferative Neoplasm

United States
Seattle Gummy Company
Frontage Clinical Services, Inc.; Frontage Laboratories, Inc.

Not yet recruiting

Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg

Allergy
Hadassah Medical Organization

Recruiting

Bioequivalence Assessment of Cannabidiol (CBD) Administrated in Oral Formulations

Pain

Israel
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
Basilea Pharmaceutica

Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Fungal Infection

Netherlands
Sanofi

Completed

A Study of the Safety, Tolerability, and Bioavailability of Orally Administered Venglustat in Healthy Adult Participants

Healthy Volunteers

United States
University of Exeter

Withdrawn

Bioavailability of Orally Ingested Vitamin C (ABBA)

Healthy

United Kingdom
Pfizer

Completed

A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults

Healthy Participants

Netherlands
Pfizer

Completed

Relative Bioavailability Study of Nirmatrelvir/Ritonavir Oral Powder Relative to the Commercial Tablets and Estimation of the Effect of Food on Bioavailability of the Nirmatrelvir/Ritonavir Oral Powder in Healthy Participants.

Biological Availability

Belgium
Incyte Corporation

Active, not recruiting

A Study to Evaluate the Relative Bioavailability of Ruxolitinib Extended Release (XR) Tablets Compared With Ruxolitinib Immediate Release (IR) Tablets Administered Orally in Healthy Participants.

Healthy Participants

United States
Aelis Farma
National Institute on Drug Abuse (NIDA)

Active, not recruiting

The Effect of Food on the Oral Bioavailability of AEF0117 in Healthy Volunteers

Marijuana Abuse

United States
UCB Biopharma SRL

Completed

A Relative Bioavailability Study of Staccato Alprazolam Versus Oral Alprazolam in Healthy Study Participants

Healthy Participants

United States
Industrial Farmacéutica Cantabria, S.A.

Enrolling by invitation

Bioavailability Clinical Trial of Oral Minoxidil 1 mg

Healthy

Spain
AstraZeneca
Parexel

Completed

A Study to Compare Bioavailability of AZD5055 Film-coated Tablet With AZD5055 Oral Suspension and to Assess the Effect of Food and an Acid Reducing Agent on Pharmacokinetics (PK) of AZD5055 in Healthy Subjects.

Healthy Volunteers

United States
University Hospital, Basel, Switzerland

Completed

LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects (LSD-Bio)

Healthy

Switzerland
Bionos Biotech S.L.

Active, not recruiting

Clinical Evaluation of the Magnesium Absorption Kinetics in Human Plasma Upon Oral Intake of Magnesium-based Products

Healthy Volunteers

Spain
M.D. Anderson Cancer Center

Active, not recruiting

A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous Cladribine

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia

United States
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.

Food-drug Interaction

Canada
Bionos Biotech S.L.

Completed

Bioavailability of Different Collagen-based Treatments After Oral Intake

Healthy Volunteers

Spain
Dompé Farmaceutici S.p.A

Completed

A Single Dose Study About the Influence of Food on the Oral Bioavailability of Ladarixin Capsule in Healthy Volunteers

no Condition

Switzerland
Alexion Pharmaceuticals, Inc.

Completed

Bioavailability Study of 2 Oral Formulations of ALXN1840

Healthy

Australia
Medicines for Malaria Venture

Completed

Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. (PedPQP(BA/FE))

Malaria

Tanzania
Mitsubishi Tanabe Pharma Corporation

Completed

Comparative Bioavailability Study of Oral Edaravone Administered Orally and Via a Nasogastric Tube

Healthy Adult Subjects

Japan
Jiangsu HengRui Medicine Co., Ltd.

Completed

To Assess SHR0302 Oral Solutions and Tablets in Healthy Subjects Clinical Studies of Relative Bioavailability

Graft-versus-host Disease

China
Vinay Badhwar

Enrolling by invitation

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) (OPTIMAL)

Endocarditis

United States
University of Limerick
Marigot Ltd.; Enterprise Ireland

Completed

Bioavailability of Plant Protein Amino Acids

Bioavailability of Amino Acids Following Oral Ingestion of Plant-Based Proteins in Young, Healthy Men

Ireland
Galapagos NV

Completed

Relative Bioavailability and Effect of Food Study With an Oral Mini-tablet Formulation of Filgotinib in Healthy Subjects

Bioavailability

Canada
University of Wisconsin, Madison
Wisconsin Alumni Research Foundation

Completed

Fruit-based Chewing Gums for Improving Oral Health

Oral Health

United States
Corcept Therapeutics

Completed

A Study to Evaluate the Effect of Food on the Oral Bioavailability of Relacorilant in Healthy Subjects

Healthy

United States
Imperial Brands PLC

Completed

A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products

Healthy Volunteers

Sweden
CTI BioPharma
Covance

Completed

Study to Assess the Relative Bioavailability of Pacritinib Following Oral Administration as Capsule and Solution Formulations in Healthy Subjects

Healthy Subjects

United States
Acasti Pharma Inc.

Completed

Relative Bioavailability of Intravenous GTX-104 Compared to Oral Nimodipine Capsules in Healthy Subjects

Aneurysmal Subarachnoid Hemorrhage

Canada
Bristol-Myers Squibb

Completed

A Study of Milvexian Using an IV Microtracer With Additional Formulation and Food Effect Comparison in Healthy Participants

Healthy Volunteers

United Kingdom
TAHO Pharmaceuticals Ltd.

Completed

Comparative Bioavailability Study of TAH3311 5 mg Oral Dissolving Film vs ELIQUIS® 5 mg Tablet in Healthy Volunteers (TAH-12288201)

Healthy Volunteers | Fasting | Fed

United States
AstraZeneca

Completed

Baxdrostat Bioavailability and Bioequivalence Study

Hypertension

United States
Fundació Eurecat
URIACH, S.L.

Completed

Oral Bioavailability of Two Melatonin Supplements (MELFENIL)

Bioavailability

Spain
Eisai Inc.

Completed

Escalation Study to Determine Bioavailability of a Single Oral Dose of Decitabine in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States

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