Search clinical trials for: Patient-Derived Organoids

Total 90 results

Chinese University of Hong Kong

Not yet recruiting

Prospective Clinical Validation of Next Generation Sequencing (NGS) and Patient-Derived Tumor Organoids (PDO) Guided Therapy in Patients With Advanced/ Inoperable Solid Tumors (PDO)

Hepatocellular Carcinoma | Colorectal Cancer

Hong Kong
University Hospital, Akershus
Oslo University Hospital; Oncosyne AS

Recruiting

Tailoring Treatment in Colorectal Cancer (TargetCRC)

Colorectal Neoplasms

Norway
Duke University

Completed

Patient-Derived Organoids for Rectal Cancer

Rectum Cancer

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Staphylococcal Infections

United States
King's College London

Not yet recruiting

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases (PDO)

Breast Neoplasms
Kors van der Ent
European Union

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF (CHOICES)

Cystic Fibrosis

Netherlands, Spain, France, Germany, Italy, United Kingdom, Portugal, Belgium, Sweden
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers (I-COMET)

Colon Cancer | Peritoneal Carcinoma

France
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Validation of a Preclinical Model Based on Patient-derived Organoids for the Study of the Gut-joint Axis in Spondyloarthritis (ORGANOSPA)

Inflammatory Bowel Diseases | Spondyloarthritis

Italy
Zhejiang University
Newislet Biotechnology (Shanghai) Ltd.

Recruiting

The Use of Islet Organoids in the Treatment of Pancreatic Surgery-related Diabetes

T3c Diabetes

China
University Hospital, Toulouse

Not yet recruiting

Modeling Ocular Developmental Diseases From 3D Cultures of Optic Vesicle Organoids Derived From hiPSCs of Patients With Ocular Malformations (OrganoEye)

Eye Abnormalities

France
GlaxoSmithKline

Not yet recruiting

Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Patient-derived Organoids and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)

Lung Cancer, Non-Small Cell

United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Hepatocellular Carcinoma Liver Organoids (HELIO)

Hepatocellular Carcinoma

Italy
Jianjun Yang,MD

Recruiting

Research on the Correlation Between Organoid Drug Sensitivity Testing and Precise Treatment of Gastrointestinal Tumors

Gastrointestinal Tumors，3D Organoids，Drug Sensitivity

China
Chongqing University Cancer Hospital

Recruiting

Artificial Intelligence Model for Growth Prediction of Ovarian Cancer Organoids

Ovarian Cancer

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Breast Cancer Subtype Characterization Through Patient's Derived Organoids. (BCinsightPDO)

Breast Cancer | Organoids

Italy
University of Udine

Recruiting

Tumor Microenvironment in Ovarian Cancer (MICO)

Ovarian Cancer Stage IV | Ovarian Cancer Stage III

Italy
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Recruiting

Generation of Lung Tumor Organoids From Patients Undergoing Diagnostic Bronchoscopy

Generation of Lung Cancer Organoids

Italy
Centro di Riferimento Oncologico - Aviano

Recruiting

Patients Derived Organoids as a Promising Tool to Tailor Ovarian Cancer Therapies (PANDORA). (PANDORA)

Ovarian Cancer

Italy
University of Bern
Spitalzentrum Biel

Not yet recruiting

Precise Neoadjuvant Chemoresection of Low Grade NMIBC (POLO)

Bladder Cancer | Non-muscle Invasive Bladder Cancer | Low-risk

Switzerland
Dong Bing Zhao

Recruiting

Gastric Cancer Organoids in the Screening of Neoadjuvant Drugs

Gastric Cancer | Neoadjuvant Therapy | Organoid

China
Peking Union Medical College Hospital

Not yet recruiting

Construction of Gynecological Tumor Organoids

Gynecologic Cancer | Organoid
Second Affiliated Hospital, School of Medicine,...

Recruiting

Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer (ONAC)

Breast Cancer | Neoadjuvant Chemotherapy | Organoids

China
Guangdong Provincial People's Hospital
Sun Yat-sen University; First Affiliated Hospital, Sun Yat-Sen University; Shantou...

Recruiting

Organoid-based Functional Precision Therapy for Advanced Breast Cancer (ORIENTA)

Advanced Breast Cancer | HER2-negative Breast Cancer

China
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Gastric Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Gastric Cancer | Organoids

China
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Colorectal Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Colorectal Cancer | Organoids

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Patients Derived Organoids in Ovarian Cancer (PICTURE)

Ovarian Cancer

Italy
National Taiwan University Hospital

Recruiting

Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling-Establish Reliably Electrophysiological Readouts From Human-induced Pluripotent Stem Cells (hiPSCs)-Derived Cerebral Organoids and Surgically Dissected Human Live Brains

Brain Diseases | Brain Tumor

Taiwan
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Engineering Immune Organoids to Study Pediatric Cancer (IMMUNEORGANOID)

Sarcoma | Brain Tumor | Neuroblastoma | Kidney Tumor

France
Wuhan Union Hospital, China

Not yet recruiting

Molecular Study and Precision Medicine for Colorectal Cancer (MSPM)

Recurrent Colorectal Carcinoma | Advanced Colorectal Carcinoma

China
Maastricht Radiation Oncology
Maastricht University Medical Center

Recruiting

Vestibular Schwannoma Organoids

Vestibular Schwannoma

Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...
Catholic University of the Sacred Heart; Heinrich-Heine University, Duesseldorf and other collaborators

Recruiting

Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs (2253)

Glioblastoma | Glioma, Malignant

Italy
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
Affiliated Hospital of Jiangnan University

Recruiting

Organoids Predict Therapeutic Response in Patients With Multi-line Drug-resistant Lung Cancer

Lung Cancer | Organoid

China
Chengjun Sui,MD

Not yet recruiting

Clinical Transformation of Organoid Model to Predict the Efficacy of GC in the Treatment of Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma | Organoids
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Study on Consistency Evaluation for Drug Sensitivity of Patient-Derived Organoid Model From Cholangiocarcinoma Patients

Cholangiocarcinoma

China
Ajou University School of Medicine

Recruiting

Establishment of Pancreas Cancer and Cancer-associated Fibroblast Using EUS-guided Biopsy Samples

Pancreas Adenocarcinoma

Korea, Republic of
National University Hospital, Singapore
National University of Singapore

Recruiting

Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma

Glioma, Astrocytic

Singapore
Henan Cancer Hospital

Not yet recruiting

A Study on the Potential Benefit of Neoadjuvant Therapy for AGC Patients

Early Gastric Cancer | Tumor Organoids
Institut National de la Santé Et de la Recherche...
National Research Agency, France

Recruiting

Preclinical Evaluation of Multimodal Therapeutic Strategies in Intestinal Irradiation and Inflammatory Bowel Disease From Organoids (INTRUST)

Inflammatory Bowel Diseases | Radiation Enteritis

France
Guy's and St Thomas' NHS Foundation Trust

Recruiting

SOTO: Treatment Sensitivity of Organoids to Predict Treatment Outcome

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United Kingdom
Prof. Dr. med. Dres. h.c. Jan Schmidt, MME

Recruiting

Patient-derived Organoids Drug Screen in Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreas Adenocarcinoma | Pancreas Cancer | Pancreas Neoplasm

Switzerland
Jun Zhang, MD, PhD
Nilogen Oncosystems

Recruiting

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC (TUMORIN)

NSCLC | Lung Cancer | NSCLC Stage IV

United States
University Hospital Inselspital, Berne
University of Bern

Recruiting

Bern Human Organoid-Study to Study Host-microbe Interaction (humorg)

Microbiota | Organoids | Allergy and Immunology

Switzerland
Maastricht Radiation Oncology
Maastricht University Medical Center; Maastricht University

Recruiting

Developing Breast (Cancer) Organoids

Breast Cancer

Netherlands
Chongqing University Cancer Hospital

Recruiting

The Culture of Advanced/Recurrent/Metastatic Colorectal Cancer Organoids and Drug Screening

Colorectal Cancer

China
Rennes University Hospital

Recruiting

Intestinal Organoids (BIOÏDES)

Digestive System Diseases | Crohn Disease | Inflammatory Bowel Disease, Ulcerative Colitis Type

France
Chongqing University Cancer Hospital

Recruiting

The Culture of Advanced or Recurrent Ovarian Cancer Organoids and Drug Screening

Ovarian Neoplasms

China
University Hospital, Montpellier

Recruiting

Using Embryo Organoids to Discover Human-specific Mechanisms of Preimplantation Embryo Development and Early Pregnancy (EMBRYOx)

Infertility

France
Changhai Hospital

Recruiting

Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis

Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases

China
National University Hospital, Singapore

Recruiting

Quadratic Phenotypic Optimisation Platform (QPOP) Utilisation to Enhance Selection of Patient Therapy Through Patient Derived Organoids in Breast Cancer (QUEST)

Breast Cancer

Singapore

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