Search clinical trials for: Pharmacokinetics of asparaginase

Total 429281 results

Aarhus University Hospital

Completed

Pharmacokinetics and Immunogenicity of the First Doses of PEG-Asparaginase -An ALLTogether Pilot Study

Acute Lymphoblastic Leukemia

Denmark
St. Jude Children's Research Hospital
Baylor College of Medicine; Gateway for Cancer Research

Active, not recruiting

Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I

Acute Lymphoblastic Leukemia

United States, Canada
Aarhus University Hospital

Completed

Pharmacokinetics of Asparaginase and Antibody Formation in Interfant-06

Leukemia

Denmark, Finland, Sweden, Iceland, Norway
Mingzhi Zhang
Shanxi Province Cancer Hospital; Wuhan University; Qingdao University; Wuhan Union... and other collaborators

Unknown

Treatment of Natural Killer/T Cell Lymphoma-I/II (CTTNKTL-I/II)

Nasal and Nasal-type NK/T-cell Lymphoma

China
Associazione Italiana Ematologia Oncologia Pediatrica

Completed

Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia (AIEOP LLA 2000)

Leukemia
Bial - Portela C S.A.

Completed

The Effect of BIA 2-093 on the Steady-state Pharmacokinetics of Digoxin

Epilepsy

Portugal
Atrogi AB

Recruiting

The Attractive 2 Trial - Pharmacokinetics of ATR-258 Oral Capsule vs. Oral Solution Formulations in Healthy Volunteers (Attractive 2)

Type2diabetes

Sweden
Ove Andersen
Mayo Clinic; University of Southern Denmark

Not yet recruiting

Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity

Healthy | Multimorbidity
Athira Pharma
Fortrea Holdings, Inc.

Recruiting

A SAD and MAD Study of the Safety, Tolerability, and Pharmacokinetics of ATH-1105

Healthy Volunteers

United States
Celgene

Not yet recruiting

A Study to Evaluate the Drug Levels, Metabolism and Excretion, and Absolute Bioavailability of BMS-986365 in Healthy Male Participants

Healthy Volunteers

United States
Ionis Pharmaceuticals, Inc.

Not yet recruiting

ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
GlaxoSmithKline

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

Solid Tumors

United States, Canada, Australia
Pharmosa Biopharm Inc.
Novotech (New Zealand) Limited

Not yet recruiting

Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults

Pulmonary Arterial Hypertension

New Zealand
Gannex Pharma Co., Ltd.

Not yet recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Healthy Subjects

NASH
SpliSense Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Imperial College London

Recruiting

Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment (DATATDM)

Pharmacokinetics | Drug-Related Side Effects and Adverse Reactions | Infections, Bacterial | Drug Monitoring

United Kingdom
University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium
Xie Kangjie

Recruiting

Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia

Pharmacokinetics | Hypoproteinemia | Ciprofol

China
Bristol-Myers Squibb

Not yet recruiting

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Hepatic Impairment | Healthy Participants
Celgene

Not yet recruiting

Study to Evaluate Safety, Drug Levels, Food and Relative Bioavailability of BMS-986365 in Healthy Adult Male Participants

Healthy Participants

United States
Incyte Corporation

Recruiting

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics When Administered Orally to Healthy Adult Participants

Healthy Participants

United States
AbbVie

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABBV-1088 Oral Dose in Healthy Adult Participants.

Healthy Volunteers

United States
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Malaria Research and Training...

Not yet recruiting

Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali

Malaria,Falciparum
Novartis Pharmaceuticals

Not yet recruiting

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Systemic Lupus Erythematosus | Sjogren Disease
Celgene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity

Healthy Participants

United States
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Aliada Therapeutics

Not yet recruiting

A Phase 1 Trial to Assess Safety, Tolerability and Pharmacokinetics of ALIA-1758 in Healthy Participants

Alzheimer Disease

United States
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
National Cancer Institute (NCI)

Not yet recruiting

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Carcinoma, Neuroendocrine | Tumor, Neuroendocrine | Tumors, Neuroendocrine | Neuroendocrine; Carcinoma | Small Cell; Receptors

United States
TOLREMO therapeutics AG

Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors (TT-CSP-001)

Cancer | Adult Solid Tumor | Advanced Solid Tumor | Adult Disease

Spain, Switzerland
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
AbbVie

Not yet recruiting

A Study in Healthy Adult Participants to Assess the Pharmacokinetics, Immunogenicity, Safety, and Tolerability of a Ravagalimab Subcutaneous Formulation in a Pre-Filled Syringe

Healthy Volunteers
GE Healthcare
PPD; Fortrea

Not yet recruiting

A Phase 1, Dose-Escalation, Positron Emission Tomography Study to Assess the Safety, Pharmacokinetics, Dosimetry and Biodistribution of GEH200521 (18F) Injection Co-Administered With GEH200520 Injection in Healthy Volunteers

Healthy Volunteers

United States
Oneness Biotech Co., Ltd.

Not yet recruiting

Evaluate Efficacy, Pharmacokinetics, and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis
Korea United Pharm. Inc.

Not yet recruiting

A Study to Compare and Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of UI059 and UIC202201

Gastro-Intestinal Disorder

Korea, Republic of
MediLink Therapeutics (Suzhou) Co., Ltd.

Not yet recruiting

A Phase 1 Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Advanced Solid Tumors

Advanced Solid Tumors

China
Pelage Pharmaceuticals, Inc.

Not yet recruiting

Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA

Androgenetic Alopecia
Pfizer

Not yet recruiting

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

Healthy Participants
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
GRIN Therapeutics, Inc.

Recruiting

A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Tuberous Sclerosis Complex | Focal Cortical Dysplasia

Spain, United Kingdom, Australia, Belgium, Canada, Italy, Poland
Norroy Bioscience Co., LTD

Recruiting

Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM005 in Patients

Clear Cell Renal Cell Carcinoma Metastatic

China
AstraZeneca

Recruiting

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone

Hepatic Impairment

United States
Clinuvel Europe Limited

Recruiting

Pharmacokinetics of Afamelanotide in EPP Patients

Erythropoietic Protoporphyria

Belgium, Netherlands
Norroy Bioscience Co., LTD

Recruiting

Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM032 in Patients

Prostate Cancer

China
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Not yet recruiting

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization ((SEEtoTREAT))

Prostate Cancer | Advanced Cancer
Universitair Ziekenhuis Brussel

Recruiting

Pharmacokinetics of Inhaled Levosimendan (Symbiov)

Left Ventricular Dysfunction

Belgium
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SHR-4597 Inhalation in Healthy Subjects and Asthmatic Patients

Healthy Subjects | Asthmatic Patients
MediLink Therapeutics (Suzhou) Co., Ltd.
Hoffmann-La Roche

Recruiting

A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States

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