Search clinical trials for: Phase 1, AZD5069, safety and tolerability, healthy volunteer,

Total 475792 results

AstraZeneca

Completed

AZD5069 Neutrophil Function Study

Chemokine Receptor 2 (CXCR2) Antagonist

United Kingdom
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Effect of Multiple Dosing With AZD 4721 and/or With AZD 5069

Chronic Obstructive Pulmonary Disease (COPD).

United Kingdom
AstraZeneca

Completed

Japanese Single and Multiple Ascending Dose (JSMAD), Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) Study of AZD5069 (JSMAD)

Healthy

United Kingdom
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Ascending Doses of AZD5069 in Healthy Volunteers

Healthy

United Kingdom
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Activity of AZD5069 When Given as a Single Dose to Healthy Male and/or Female Subjects

Healthy

United Kingdom
The University of Hong Kong

Recruiting

To Evaluate Safety & Immunogenicity of DelNS1-2019-nCoV-RBD-OPT1 for COVID-19 in Healthy Adults Received 2 Doses of BNT162b2

Covid19

Hong Kong
The University of Hong Kong
Immuno Cure 3 Limited

Recruiting

A Study to Evaluate Safety & Immunogenicity of SARS-CoV-2 DNA Vaccine Delivered Intramuscularly Followed by Electroporation for COVID-19

Covid19

Hong Kong
Vitae Pharmaceuticals Inc., an Allergan affiliate

Completed

An Ascending Multiple Dose Study With VTP-43742 in Healthy Volunteers

Psoriasis

United States
International Rescue Committee
University of Southern California; Jordan University of Science and Technology

Terminated

Community Models for Hypertension and Diabetes Care for Refugees

Hypertension | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Comorbidities and Coexisting Conditions

United States
AstraZeneca

Completed

Safety, Tolerability, and Pharmacokinetics of AZD7268 After Single Ascending Oral Doses in Healthy Subjects

Healthy Volunteer

United States
Celgene

Completed

Relative Bioavailability and PPI Effects of CC-92480 Test and Reference Formulations in Healthy Subjects

Healthy Volunteer

United States
Genzyme, a Sanofi Company

Completed

A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blend Formulations of Eliglustat in Healthy Adult Subjects

Healthy Volunteer

United States
AstraZeneca

Completed

A 4 Week Study to Investigate the Safety and Tolerability of AZD5069 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (CIRRUS)

Scientific Terminology Chronic Obstructive Pulmonary Disease (COPD) | Laymen Terminology Chronic Bronchitis and Emphysema

Bulgaria, Germany, Hungary, Ukraine
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Healthy Volunteer

United States
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response

Healthy Volunteer

United States
Celgene

Completed

Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122

Healthy Volunteer

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers

Healthy Volunteer/DDI Study

United Kingdom
AstraZeneca

Completed

A Phase II Study to Evaluate the Efficacy, Safety and Tolerability of AZD5069 in Patients With Uncontrolled Persistent Asthma. (NIMBUS)

Asthma

Bulgaria, Czech Republic, Mexico, Poland, Russian Federation, South Africa, United Kingdom, Germany, Romania, Ukraine, Canada, Hungary, Slovakia
Shionogi

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults

Healthy Volunteer

United States, Japan
Agios Pharmaceuticals, Inc.

Completed

A Phase I Study of AG-348 in Healthy Volunteers (AG-348 SAD)

Healthy Volunteer

United States
Endo Pharmaceuticals

Completed

Safety and Pharmacokinetics of Vasopressin in Healthy Volunteers

Healthy Volunteer Safety Study

United States
Eli Lilly and Company

Completed

A Study of LY3009104(Baricitinib) for Healthy Subjects

Healthy Volunteer

United States
Eli Lilly and Company

Completed

A Study of LY2495655 in Healthy Subjects

Healthy Volunteer

United States
Eli Lilly and Company

Completed

A Study of LY110140 in Healthy Japanese Male Participants

Healthy Volunteer

Japan
Aravive, Inc.

Completed

A Phase 1 AVB-S6-500 Safety and Tolerability Study

Healthy Volunteer

United States
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Healthy Participants

Healthy Volunteer Study

United Kingdom
Vanda Pharmaceuticals
Mayo Clinic

Completed

Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Phase I Bioavailability and Pharmacokinetic Study of [14C]-Ipatasertib Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy Volunteer

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Safety, Pharmacokinetic, and Pharmacodynamic Study of TS-142 in Healthy Subjects

Healthy Volunteer

Japan
Eisai Co., Ltd.

Completed

A Single and Multiple Dose Study of Lemborexant in Healthy Chinese Participants

Healthy Volunteer

China
AstraZeneca

Completed

Distribution of Neutrophils in Bronchial Mucosal Tissue in Asthma Patients Before and After 4 Weeks Treatment With AZD 5069

Asthma

Germany
University of Oxford
Bill and Melinda Gates Foundation; University Hospitals Bristol and Weston...

Recruiting

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

Malaria,Falciparum

United Kingdom
Meiji Seika Pharma Co., Ltd.

Completed

A Phase 1 Pharmacokinetic Bioequivalence Study of DMB-3113 and Adalimumab in Healthy Japanese Adult Male Subjects (DMB-3113-1)

Healthy Volunteer

Japan
MedImmune LLC

Completed

Phase 1 Single-ascending Dose Study to Evaluate Safety and Tolerability of MEDI4920 in Healthy Adults

Healthy Volunteer

United Kingdom
Comanche Biopharma

Recruiting

Study of CBP-4888 in Healthy, Non-Pregnant Female Subjects

Healthy Volunteer Study

United States
Genzyme, a Sanofi Company

Completed

A Phase 1 Study Evaluating Eliglustat's Effects on Pharmacokinetics, Safety & Tolerability of Digoxin in Healthy Adults

Healthy Volunteer

United States
AstraZeneca
Quintiles, Inc.

Completed

This Study Will Investigate How Food and Age Effect the Way the Body Handles the AZD5069 Drug Given as a Oral Dose

Chronic Obstructive Pulmonary Disease

United Kingdom
Heat Biologics

Withdrawn

A Phase 1 Study of PTX-35 in Healthy Volunteers

Healthy Volunteer
Kyma Medical Technologies

Completed

Vital Signs Validation Study of the μ-Cor System (ViVUS Validation) (ViVUS)

Health Volunteer Validation Study
Avanir Pharmaceuticals

Completed

A Phase 1 Study Comparing AVP-786 With AVP-923

Healthy Volunteer

United States
AstraZeneca

Completed

Open Label, Healthy Volunteers, ADME Study With Single Oral Administration of [14C] AZD5069

Healthy

United Kingdom
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis (STRATUS)

Bronchiectasis | Lung Disease | Respiratory Diseases

Czech Republic, United Kingdom, Poland
Fresenius Medical Care North America

Completed

Acid-Base Composition With Use of hemoDialysates (ABChD)

End Stage Renal Disease

United States
Neomatrix Therapeutics, Inc.
United States Department of Defense

Not yet recruiting

Phase 1 Healthy Volunteer Burn Therapy Study

Burns

United States
University of Oxford

Recruiting

A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of the Blood-stage Malaria Candidate Vaccines RH5.1 in Matrix-M and R78C in Matrix-M in Healthy UK Adults

Malaria, Falciparum

United Kingdom
Celgene

Completed

A Phase 1 QT Study in Healthy Male Subjects (QT/QTc)

Clinical Pharmacology, Healthy Volunteer Study

United States
Institute of Cancer Research, United Kingdom
AstraZeneca; Astellas Pharma Inc; Prostate Cancer UK

Terminated

Combination Study of AZD5069 and Enzalutamide. (ACE)

Metastatic Castration Resistant Prostate Cancer

United Kingdom, Switzerland
Hoffmann-La Roche

Completed

A Phase 1 Study of RO6806127 in Healthy Male Volunteers

Healthy Volunteer

United States
Huazhong University of Science and Technology

Completed

Magnetic Resonance Neurography Analysis of Healthy Human Thoracic Dorsal Root Ganglion

Dorsal Root Ganglion

China

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