Search clinical trials for: Pulmonary Safety

Total 55073 results

Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia (EMPACTA)

COVID-19 Pneumonia

United States, Peru, Kenya, Mexico, Brazil, South Africa
United Therapeutics

Terminated

A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) (PERFECT)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United States, Israel, Argentina, Puerto Rico
Seoul National University Hospital

Completed

A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)

Cardiovascular Abnormalities | Pulmonary Valve Insufficiency | Pulmonary Valve Stenosis | Congenital Heart Defects

Korea, Republic of
Attgeno AB

Completed

A First-in-Human Study to Assess the Safety and Tolerability of PDNO

Pulmonary Hypertension

Sweden
AmMax Bio, Inc.

Withdrawn

A Phase 2 Study to Evaluate Safety and Efficacy of AMB-05X in Subjects With Idiopathic Pulmonary Fibrosis

IPF
Corbus Pharmaceuticals Inc.
Cystic Fibrosis Foundation

Completed

Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis

Cystic Fibrosis

United States, United Kingdom, Sweden, Canada, France, Austria, Germany, Netherlands, Italy, Belgium, Portugal, Bulgaria, Czechia, Greece, Hungary, Poland, Romania, Russian Federation, Serbia, Slovakia, Spain
Postgraduate Institute of Medical Education and...

Completed

Efficacy and Safety of Two Glucocorticoid Regimens in the Treatment of Sarcoidosis (SARCORT)

Sarcoidosis

India
Zambon SpA

Completed

A Clinical Trial to Compare the Efficacy and Safety of 1-week Treatment of Intravenous N-acetylcysteine (NAC) 600 mg Twice Daily, Ambroxol Hydrochloride 30 mg Twice Daily and Placebo as Expectorant Therapies in Adult Chinese Patients With Respiratory Tract Diseases and Abnormal Mucus Secretions

Respiratory Tract Diseases | Abnormal Mucus Secretions

China
Boehringer Ingelheim

Completed

Safety of Tiotropium + Olodaterol in Chronic Obstructive Pulmonary Disease (COPD) Patients in Taiwan: a Non-interventional Study Based on the Taiwan National Health Insurance (NHI) Data

Pulmonary Disease, Chronic Obstructive

China
Hoffmann-La Roche

Completed

A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma

Asthma

Korea, Republic of, United States, Belgium, Czechia, Germany, Peru, Bulgaria, Russian Federation, Argentina, Ukraine, Canada, Poland, South Africa, New Zealand, Romania
Ionis Pharmaceuticals, Inc.

Terminated

A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

Germany, Czechia, Hungary, United Kingdom
Sound Pharmaceuticals, Incorporated
Medical University of South Carolina; Cystic Fibrosis Foundation

Enrolling by invitation

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

Ototoxicity

United States
Aspen Global Incorporated

Terminated

Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study Safety and Efficacy of Danaparoid vs Argatroban (HITSOVA)

Heparin-induced Thrombocytopenia

United States, Bosnia and Herzegovina, Canada, France, Germany, Italy, Poland, Russian Federation, Serbia
Pulmongene Ltd.

Completed

A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015

Idiopathic Pulmonary Fibrosis

Australia
Aerami Therapeutics

Completed

Safety, Tolerability, & Pharmacokinetics Study of Single & Multiple Inhaled Doses of Imatinib Inhalation Solution

Pulmonary Arterial Hypertension

Australia
Novartis Pharmaceuticals

Completed

Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD

Pulmonary Disease, Chronic Obstructive

United States, Australia, Canada, Hungary, Japan, Czechia
National Institute of Allergy and Infectious Diseases...

Completed

Andes Virus DNA Vaccine for the Prevention of Hantavirus Pulmonary Syndrome Using the PharmaJet Stratis(R) Needle-Free Injection Delivery Device

Immunisation | Hantavirus Pulmonary Infection

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Ukraine, Argentina, Chile, Poland, Russian Federation, Turkey, United States, Australia, Canada, Germany
Global Alliance for TB Drug Development

Completed

Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA1)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, Hungary, Spain, Germany, United Kingdom, Denmark, Lithuania, Romania, Russian Federation, South Africa, Ukraine
Respira Therapeutics, Inc.

Completed

A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234

Healthy Volunteer

Australia
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Active, not recruiting

A Dose Ranging Placebo-controlled Double-blind Study to Evaluate the Safety, Pharmacokinetics and Efficacy of 610 in Participants With Severe Eosinophilic Asthma

Asthma

China
Enyo Pharma

Completed

A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Taiwan
Hoffmann-La Roche

Completed

A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s)

Small Cell Lung Carcinoma | Hepatocellular Carcinoma | Carcinoma, Non-Small Cell Lung | Urothelial Carcinoma | Triple Negative Breast Carcinoma

Korea, Republic of
PhaseBio Pharmaceuticals Inc.

Terminated

Phase 2 Study to Assess Safety, Tolerability and Efficacy of Once Weekly SC Pemziviptadil (PB1046) in Subjects With Symptomatic PAH (VIP)

Pulmonary Arterial Hypertension

United States
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
Bellerophon

Completed

A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or Sarcoidosis

Pulmonary Fibrosis | Pulmonary Hypertension | Sarcoidosis, Pulmonary

United States
United Therapeutics

Completed

Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE

Pulmonary Hypertension | Interstitial Lung Disease | Combined Pulmonary Fibrosis and Emphysema

United States, Puerto Rico
Technische Universität Dresden
Boehringer Ingelheim; GWT-TUD GmbH

Completed

Investigating Significant Health Trends in Idiopathic Pulmonary Fibrosis (INSIGHTS-IPF)

Idiopathic Pulmonary Fibrosis

Germany
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Safety of Diagnosis and Therapy in the Inpatient Setting (PSLL2-0)

Pneumonia | Sepsis | Delirium | Confusion | Hip Pain Chronic | Hypoxia | Back Pain | Vomiting | Abdominal Pain | Diarrhea | Cough | Asthma | Chest Pain | Neck Pain | Fever | Cellulitis | Syncope | Headache | Deep Vein Thrombosis | Venous Thromboembolism | Soft Tissue Infections | Failure to Thrive | COPD | Pulmonary Embolism | Dyspnea | Leg Pain | Mental... and other conditions

United States
Algernon Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of NP-120 on Idiopathic Pulmonary Fibrosis and Its Associated Cough

Idiopathic Pulmonary Fibrosis

Australia, New Zealand
Beijing Chest Hospital

Active, not recruiting

Safety and Effectiveness of Delamanid-containing Regimen for MDR-TB Patients in China

Multidrug Resistant Tuberculosis

China
Archivel Farma S.L.
London School of Hygiene and Tropical Medicine

Terminated

Safety of RUTI® Vaccination in MDR-TB Patients

Tuberculosis, Multidrug Resistant

Ukraine
RenJi Hospital
The First Affiliated Hospital with Nanjing Medical University; Shanghai Zhongshan... and other collaborators

Completed

Efficacy and Safety Study of Ambrisentan in Chinese Patients With Pulmonary Arterial Hypertension (AMBLE)

Pulmonary Arterial Hypertension

China
Boehringer Ingelheim

Completed

Efficacy and Safety Comparison of Tiotropium Daily + Salmeterol Daily or Twice Daily Versus Tiotropium Daily in Patients With COPD

Pulmonary Disease, Chronic Obstructive

Germany
National Institute of Allergy and Infectious Diseases...

Completed

Adaptive COVID-19 Treatment Trial 4 (ACTT-4)

COVID-19

United States, Japan, Mexico, Singapore, Korea, Republic of
Janssen Research & Development, LLC

Completed

A Study to Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Participants Infected With Respiratory Syncytial Virus

Respiratory Syncytial Virus Infections

United States, Taiwan, Japan, Korea, Republic of, France, Mexico, Brazil, Sweden, Argentina, Ukraine, Canada, Spain, Germany, Poland, Belgium, Russian Federation, South Africa, Australia, Bulgaria
GlaxoSmithKline

Completed

Study to Assess the Immunogenicity and Safety of GSK's Investigational Vaccine (GSK3277511A) When Given to Healthy Smokers and Ex-smokers After Administration of Shingrix Vaccine

Respiratory Disorders

France, Estonia, Spain, Finland, Italy
Boehringer Ingelheim
Eli Lilly and Company

Completed

EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)

Heart Failure

United States, Spain, Korea, Republic of, China, Germany, Belgium, Australia, Singapore, Canada, Italy, Argentina, Hungary, Czechia, Poland, Netherlands, Japan, United Kingdom, Mexico, Romania, Brazil, India, South Africa, Colombia
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

Alpha1-Antitrypsin Deficiency

United States, Germany, Canada, Ireland, Sweden, United Kingdom
Inmunotek S.L.

Active, not recruiting

Evaluation of the Efficacy and Safety of MV130 in Chronic Obstructive Pulmonary Disease (COPD) (MV130)

Chronic Obstructive Pulmonary Disease (COPD)

Spain
MediciNova

Completed

Safety and Tolerability Study in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis | IPF

United States
National Institute of Respiratory Diseases, Mexico

Completed

Efficacy and Safety of ICS/LABA vs. LAMA/LABA in Patients With Different COPD Phenotypes.

COPD

Mexico
Global Alliance for TB Drug Development

Completed

Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects

Tuberculosis | Tuberculosis, Pulmonary

United States
Nuvaira, Inc.

Completed

Targeted Lung Denervation for Patients With Moderate to Severe COPD (AIRFLOW)

Chronic Obstructive Pulmonary Disease (COPD)

France, Belgium, Netherlands, Austria, Germany, United Kingdom
Chiesi Farmaceutici S.p.A.

Terminated

Efficacy and Safety of CHF 6532 in Patients With Uncontrolled Severe Eosinophilic Asthma (PERSEA)

Asthma; Eosinophilic

Bulgaria
Shanghai Pulmonary Hospital, Shanghai, China

Active, not recruiting

Efficacy and Safety of Sitafloxacin in the Treatment of Acute Exacerbation of Bronchiectasis in Adults

Acute Exacerbation of Bronchiectasis

China
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-BAI in Pediatric Asthmatics

Asthma

United States
Chiesi Farmaceutici S.p.A.

Terminated

A Study To InvestigateThe Safety, Tolerability And Efficacy Of Nebulised Curosurf® In Preterm Neonates With Respiratory Distress Syndrome (RDS)

Neonatal Respiratory Distress Syndrome

Italy
Nanjing First Hospital, Nanjing Medical University
Tongji Hospital; First Affiliated Hospital Xi'an Jiaotong University; The First... and other collaborators

Completed

Safety and Efficacy of Pulmonary Artery Denervation in Patients With Pulmonary Arterial Hypertension (PADN-CFDA)

Pulmonary Arterial Hypertension

China

Search clinical trials for: Pulmonary Safety

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