Search clinical trials for: Purinegic P2 Receptor Antagonists

Total 41125 results

Teva Branded Pharmaceutical Products R&D, Inc.
FHI 360

Completed

A Study to Evaluate Injection Pain and Local Tolerability Following Subcutaneous (SC) Administration of TV-46046

Contraception

Dominican Republic
Kasr El Aini Hospital

Completed

Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients (GnRh)

Endometrioma

Egypt
Bioiberica

Completed

Chondroitin Sulphate Efficay/Safety in Patients With Knee Osteoarthritis and Psoriasis

Skin Diseases | Joint Diseases | Osteoarthritis | Psoriasis | Muskuloskeletal Diseases

Spain
University of Manitoba
Manitoba Medical Service Foundation

Completed

Omega-3 Supplementation and Resistance Training

Inflammation | Sarcopenia | Dynapenia

Canada
Bayer

Completed

Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)

Menorrhagia

United States, Canada, Brazil, Mexico, Argentina
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital; MedImmune...

Completed

Amifostine for Head and Neck Irradiation in Lymphoma

Lymphoma | Non-Hodgkin's Lymphoma | Hodgkin's Disease

United States
Emory University
National Institute on Drug Abuse (NIDA); Chestnut Health Systems

Withdrawn

Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use (A-CRA/MAT)

Behavior, Addictive | Opioid-Related Disorders
Belén Retamal-Valdes

Unknown

Amoxicillin and Metronidazole During Periodontal Treatment (MOMENT)

Chronic Periodontitis

Brazil
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

Beneficial Effects of Daytime Light Exposure and Physical Activity on the Human Circadian Clock and Sleep (DayCiS)

Circadian System

Switzerland
ANRS, Emerging Infectious Diseases

Completed

4 Consecutive Days on Treatment Followed by 3 Days Off Treatment, in HIV Patients (ANRS162-4D)

HIV-1 Infection

France
Therapeutic Concepts
Janssen Scientific Affairs, LLC

Unknown

Open Label, Pilot Study of Darunavir Boosted by Cobicistat in Combination With Rilpivirine to Treat HIV+ Naïve Subjects (PREZENT)

HIV Positive

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Ropinirole Hydrochloride ER Tablets 2 mg Under Fed Condition

Healthy

India
PATH
Bill and Melinda Gates Foundation; Children's Hospital Medical Center, Cincinnati and other collaborators

Completed

Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine

Rotavirus Vaccine

South Africa
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Food Effect Study of SHR1459 on Healthy Chinese Adult Subjects

Healthy Adult Subjects

China
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; British Heart Foundation

Completed

Healthy Volunteer Study of Clopidogrel and Rifampicin

Coronary Artery Disease

United Kingdom
Washington University School of Medicine

Recruiting

Promoting Healthy Weight Across the Pregnancy and Postpartum Period (HEALTH-P2)

Obesity

United States
Rabin Medical Center
Baxter Healthcare Corporation

Unknown

TICACOS International (P2 -RMCS)

Mechanical Ventilation Complication

Israel
Novartis

Completed

Safety, Tolerability and Efficacy of Indacaterol in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States, Argentina, Germany, Spain, Canada, India, Turkey, Sweden, Italy
University of Monastir

Completed

β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation

Acute Exacerbation of Chronic Obstructive Airways Disease

Tunisia
Centre for Infectious Disease Research in Zambia
Institut National de la Santé Et de la Recherche Médicale, France; Imperial... and other collaborators

Active, not recruiting

Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa

Diarrhea | Diarrhea Rotavirus

Zambia
Handok Inc.
ABL Bio, Inc.; Compass Therapeutics

Active, not recruiting

A Study of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Advanced or Metastatic Solid Tumor Patients

P1b: Advanced Solid Tumors | P2: Biliary Tract Cancer

Korea, Republic of
University of Aberdeen
NHS Grampian

Completed

Melatonin in Pregnancy (MEL-P2)

Pregnancy

United Kingdom
Qure Healthcare, LLC

Terminated

Clinical Utility of MyProstateScore 2.0 P2

Prostate Cancer

United States
PATH
The Emmes Company, LLC

Completed

Safety and Immunogenicity Study of Trivalent P2-VP8 Subunit Rotavirus Vaccine in Adults, Toddlers and Infants

Healthy

South Africa
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Effect of Low-fat Diet on the Pharmacokinetics of Pyrotinib in Healthy Participants

Healthy Participants
First Affiliated Hospital of Fujian Medical University

Not yet recruiting

Multi-center Clinical Study on Hemoperfusion of KHA80

Uremia | Dialysis Related Complication | Uremic Osteodystrophy

China
PATH

Completed

A Phase 1 Dose Escalation Study to Examine the Safety of the P2-VP8 Rotavirus Vaccine

Rotavirus Infection

United States
University of California, San Diego

Active, not recruiting

Sedentary Behavior Interrupted Randomized Controlled Trial (P2)

Sedentary Lifestyle

United States
University of Bonn
University of Leeds; University College Cork; Universidade do Porto; University... and other collaborators

Not yet recruiting

AI4HOPE Dementia Care Planning Pilot Study 2 ( AI4HOPE2) (AI4HOPE-P2)

Dementia

Germany
University of Leeds
Centre de Recherche en Nutrition Humaine Rhone-Alpe; University of Liverpool; University of Navarra and other collaborators

Recruiting

Impact of Sweeteners on Behaviour, Physiology & Health (SWEET-WP2-P2)

Eating Behavior

Denmark, France, Spain, United Kingdom
Scott and White Hospital & Clinic
Texas A&M University

Completed

Diabetes Self-Management Models to Reduce Health Disparities (P20-P2)

Type 2 Diabetes

United States
Assistance Publique - Hôpitaux de Paris

Completed

Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

Fertility | Antral Follicle Deficit

France
Colorado State University

Completed

Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults

Receptor Blockade

United States
Assiut University

Not yet recruiting

Clinical and Diagnostic Value of Ribosomal p2 Autoantibodies in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Kansai Hepatobiliary Oncology Group

Unknown

P2 Study of Postoperative Interferon/Fluorouracil vs Cisplatin/Fluorouracil for Hepatocellular Carcinoma.

Hepatocellular Carcinoma

Japan
Chengappa, K.N. Roy, MD
National Institutes of Health (NIH)

Completed

Test of Novel Drug for Smoking Cessation (UH3-P2)

Smoking Cessation

United States
Sanofi

Completed

Study of the Tolerability of Different SAR153191 Drug Products, That Differ With Respect to Manufacturing Processes and Formulation, at Different Concentrations and Doses in Healthy Male Subjects

Rheumatoid Arthritis
Institute of Tropical Medicine, Belgium
Damien Foundation

Completed

Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2) (BE-PEOPLE P2)

Leprosy

Comoros
Imam Abdulrahman Bin Faisal University
King Fahad Armed Forces Hospital; Dammam Central Hospital

Unknown

Bedside Testing of CYP2C19 Gene for Treatment of Patients With PCI With Antiplatelet Therapy

Myocardial Infarction | Infarction | Ischemia | Coronary Artery Disease | Cardiovascular Disease | Embolism | Thrombosis | Chest Pain | Angina Pectoris | Heart Disease | Vascular Disease

Saudi Arabia
Dascena
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Baystate Health; Cape... and other collaborators

Recruiting

Machine Learning Sepsis Alert Notification Using Clinical Data (HindSight P2)

Sepsis | Septic Shock | Severe Sepsis

United States
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis (SPIRIT-P2)

Psoriatic Arthritis

United States, France, Taiwan, Spain, Australia, Germany, United Kingdom, Poland, Czechia, Italy
University of California, Los Angeles

Recruiting

Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy (P2)

Depression | Anxiety

United States
University Ghent
University of Nottingham; Oswaldo Cruz Foundation; Institut Pasteur; World Health... and other collaborators

Completed

Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2 (ConWorm)

Ascaris Lumbricoides | Ascaris Suum | Trichuris Trichiura | Trichuris Vulpis | Ancylostoma Duodenal | Ancylostoma Caninum | Ancylostoma Ceylanicum | Necator Americanus

Argentina, Australia, Brazil, Cambodia, Cameroon, Ethiopia, Tanzania, Vietnam
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences

Recruiting

Trial to Evaluate Dietary Supplements to Maintain Gut Health During Travel (P2)

Diarrhea

United States, United Kingdom
Beijing Friendship Hospital

Recruiting

Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study

Hypertension | Obesity | Sacubitril/Valsartan

China
Autotelicbio

Completed

TASO-001 in Combination With Recombinant Interleukin-2(Aldesleukin) in Advanced or Metastatic Solid Tumor

Solid Tumor

Korea, Republic of
Novan, Inc.

Completed

P2 Multi-center Study of SB204 Gel in the Treatment of Acne Vulgaris

Acne Vulgaris

United States
Uppsala University
Abbott Medical Devices; The Medicines Company; Infraredx

Completed

PROSPECT II & PROSPECT ABSORB - an Integrated Natural History Study and Randomized Trial. (P2)

Acute Coronary Syndrome (ACS)

Sweden

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