Search clinical trials for: QTc interval

Total 1969 results

Amgen

Not yet recruiting

A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants

Basic Science
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Study to Evaluate the Effect of Jaktinib on QT/QTc Interval in Healthy Participants

Healthy Participants

China
Ataturk University

Recruiting

The Effect of Combined Spinal Epidural Anaesthesia on QTc Interval Undergoing Cesarean Section

Analgesia

Turkey
Novartis Pharmaceuticals

Recruiting

Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Spain, France
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (QTc-ZX-7101A)

Influenza, Human

China
Thryv Therapeutics, Inc.

Recruiting

Study of LQT-1213 on QTc-induced Prolongation in Healthy Adult Subjects (Part1) and on Congenital Long QT in Patients Diagnosed With Type 2 or 3 Long QT Syndrome (Part 2).

Long QT Syndrome

United States
Murdoch Childrens Research Institute

Recruiting

Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG

Neoplasms | Cardiac Arrhythmia

Australia
Angion Biomedica Corp
Quotient Sciences

Not yet recruiting

Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval

Healthy Volunteer

United States
Burzynski Research Institute

Not yet recruiting

Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma (DBSG)

Brain Stem Glioma
AstraZeneca

Completed

A Study to Investigate the Effect on QTcF of Baxdrostat Compared With Placebo, Using Moxifloxacin as a Positive Control, in Healthy Participants

Healthy Participants

Germany
Rhythm Pharmaceuticals, Inc.

Completed

Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants

Healthy

United States
Haseki Training and Research Hospital

Completed

QT Changes in Geriatric Patients: a Comparison of Spinal and General Anesthesia

Sevoflurane | Anesthesia, Spinal | Long QT Syndrome

Turkey
University Hospital, Bordeaux
APHP

Completed

Protocol TRANS and QT Repolarization (QTrans)

QTc Interval | Transgender Individuals

France
Sanofi

Terminated

Effect of Tusamitamab Ravtansine on QTc Interval in Participants With Metastatic Solid Tumors (TusaRav-QT)

Neoplasm

France, United States, Belgium, Spain, Turkey
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy Participants

Pain

United States
GlaxoSmithKline

Completed

Concentration-QT Study of Paroxetine in Healthy Adults

Anxiety Disorders

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study To Evaluate The Effect Of A Supratherapeutic Dose Of MK-8189 On The QTc Interval In Participants With Schizophrenia (MK-8189-019) (TQT)

Schizophrenia

United States
Pfizer

Completed

A Study to Investigate the Effects of Sisunatovir on QTc Interval in Healthy Adult Participants.

Healthy

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers

Healthy Volunteers

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study to Evaluate the Effect of Pirtobrutinib (LOXO-305) on QTc Interval in Healthy Participants

Healthy

United States
Italfarmaco

Completed

Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC Interval

Duchenne and Becker Muscular Dystrophy | Polycytemia Vera

Canada
AN2 Therapeutics, Inc

Completed

A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects

Healthy Volunteers

United States
Cytokinetics

Completed

Study to Evaluate the Effect of Aficamten Administration on QT/QTc Interval

Healthy Participants

United States
University of California, Los Angeles
Tobacco Related Disease Research Program

Completed

Smoking and Ventricular Repolarization

Sudden Cardiac Death | Prolonged QTc Interval

United States
Ferring Pharmaceuticals

Completed

A Study to Evaluate the Effect of Carbetocin on the QT/QTc Interval in Healthy Subjects

Postpartum Hemorrhage

United States
Estetra

Completed

Effect of Estetrol Monohydrate (E4) on QTc Interval

Prolonged QTc Interval

United States
Usona Institute

Completed

An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics

Pharmacokinetics | QTc Interval

United States
Amgen

Completed

A Study to Assess the Effect of Avacopan at Therapeutic and Supratherapeutic Doses on the QT/QTc Interval in Healthy Participants

Electrocardiography

United States
Vertex Pharmaceuticals Incorporated

Completed

An Electrocardiogram Study to Evaluate the Effect of Vanzacaftor on the QT/QTc Interval in Healthy Participants

Cystic Fibrosis

United States
Eisai Inc.

Completed

A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval

Lymphomas | Refractory Solid Tumors

United States
Universitaire Ziekenhuizen KU Leuven
St. Justine's Hospital

Enrolling by invitation

QTc Intervals in Former Preterm/Extreme Low Birth Weight Infants: a Pooled Study Proposal

Preterm Birth | Qt Interval

Belgium, Canada
Mitsubishi Tanabe Pharma America Inc.

Completed

Study to Evaluate the Effect of a Single Oral Dose of MT-7117 on the QT/QTc Interval in Healthy Subjects

Healthy Subjects

United States
Jazz Pharmaceuticals

Completed

Sativex Thorough QT/QTc Study

Effects of Sativex on ECG

Canada
Vigonvita Life Sciences

Completed

Evaluate the Effect of TPN171H on the QT/QTc Interval in Healthy Volunteers

Healthy Subjects

China
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effects of Pevonedistat on the Corrected QT (QTc) Interval in Participants With Advanced Solid Tumors

Advanced Solid Neoplasm

United States
Calithera Biosciences, Inc

Completed

Effect of Sapanisertib (MLN0128) on the QTc Interval in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
BioLineRx, Ltd.
Celerion

Completed

Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects

Healthy Subjects

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Selpercatinib (LY3527723) on Corrected QT (QTc) Interval in Healthy Participants

Healthy

United States
Takeda

Withdrawn

A Study of Soticlestat in Healthy Adults To Evaluate the Effect on QTc Interval

Healthy Volunteers
Centre Hospitalier de Valence

Completed

GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers

Sensation Disorders | Taste Disorders | Taste, Metallic | Taste Disorder, Glossopharyngeal Nerve

France
Connect Biopharma Australia Pty Ltd

Completed

A Study to Investigate the Effects of CBP-307 on the Heart Rate-corrected QT Interval (QTc) in Healthy Subjects

Autoimmune Diseases

Australia, United States
Daiichi Sankyo Co., Ltd.
AstraZeneca

Completed

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer

Malignant Neoplasm of Breast

Japan
Pfizer

Completed

Evaluating QTc, PK, Safety of Gemtuzumab Ozogamicin (GO) in Patients With CD33+ R/R AML

Pharmacokinetics | Safety | ECG

Canada, Spain, United States, Hungary, Poland, United Kingdom
Concert Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers

Healthy Volunteers

United States
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy Adults

QT Intervals Changes | QTc Intervals Changes

United Kingdom
Yonsei University

Completed

The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Living Donor Liver Transplantation Under Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial

Liver Cirrhosis(Who Will Undergo Planed Liver Transplantation)

Korea, Republic of
Odonate Therapeutics, Inc.

Terminated

The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
BioMarin Pharmaceutical

Completed

A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects

Phenylketonuria

United States
Tris Pharma, Inc.
Forest Laboratories

Completed

Evaluation of the Effects of Multiple Doses of Cebranopadol on the Electrical Activity of the Heart in Healthy Subjects

Prolonged QTc Interval | Pharmacokinetic

United States

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