Search clinical trials for: Radiolabeled study

Total 118942 results

Emory University
National Institute on Drug Abuse (NIDA)

Recruiting

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3 (VNS in OUD UH3)

Opioid Use Disorder | Opioid Use | Withdrawal Symptoms

United States
Syndax Pharmaceuticals

Recruiting

Study of Radiolabeled Revumenib in Adults With Acute Leukemia

Acute Leukemia

United States
Novartis Pharmaceuticals

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma

Recurrent Adult Hodgkin Lymphoma

United States
OncoTherapy Science, Inc.

Terminated

Phase I Study of Radiolabeled OTSA101-DTPA in Patients With Relapsed or Refractory Synovial Sarcoma

Relapsed or Refractory Synovial Sarcoma

Japan
Portola Pharmaceuticals

Completed

A Healthy Volunteer PK/PD, Safety and Tolerability Study of Second Generation Andexanet Alfa

Bleeding

United States
Biogen

Completed

A Study to Evaluate Safety, Tolerability, and Distribution of a Microdose of Radiolabeled BIIB067 (99mTc-MAG3-BIIB067) Co-administered With BIIB067 (Tofersen) to Healthy Adults

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of Carbon-14-Labelled [14C] LY3372689 in Healthy Male Participants

Healthy

United States
Alexion Pharmaceuticals

Completed

Study of Radiolabeled ALXN2050 in Healthy Adult Males

Healthy

United States
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Sagimet Biosciences Inc.

Active, not recruiting

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]TVB-2640 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Male Subjects

Healthy Subjects

Netherlands
Cerus Corporation

Completed

In Vivo Study to Assess the Recovery and Survival of Radiolabeled Autologous INTERCEPT Apheresis Platelet Components Suspended in 100% Plasma Stored for up to 7 Days

Healthy

United States
Pfizer

Completed

A Study in Healthy Adult Male Participants to Assess Absorption, Distribution, Metabolism and Excretion (ADME) of Radiolabeled PF-06865571.

Healthy Participants

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Radiolabeled Danicopan in Healthy Male Participants

Healthy

New Zealand
LTN PHARMACEUTICALS, INC.

Completed

Single-Dose Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of Radiolabeled Galeterone

Healthy

United States
Perosphere Pharmaceuticals Inc, a wholly owned...
World Wide Clinical Trials Early Phase Services, LLC

Completed

An Open-label, Single-dose, Non-randomized Study of IV 14C-labeled PER977 in Healthy Male Subjects

Healthy

United States
Celgene

Completed

Radiolabeled Study of CC-122 in Healthy Subjects

Healthy Volunteers

United States
Concert Pharmaceuticals
Celerion

Completed

Study Evaluating Pharmacokinetics and Mass Balance of [14C]-CTP-543 in Healthy Adult Male Volunteers

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Study of (14C) Radiolabeled JNJ-56136379 in Healthy Male Participants

Healthy

United States
City of Hope Medical Center

Completed

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Esperion Therapeutics, Inc.

Completed

Single Radiolabeled Dose Study to Investigate the Absorption, Metabolism and Excretion of [14C]-ETC-1002

Hyperlipidemia

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Safety Study to Determine the Appropriate Dose of Antibody Against Tumor Cells to Best Target Patients With Pancreatic Cancer.

Pancreatic Cancer

United States
Eli Lilly and Company

Completed

C14 Study in Oncology Patients With Advanced and/or Metastatic Solid Tumors

Advanced Cancer

Switzerland
Celgene

Completed

Radiolabeled Study of AG-221 in Healthy Male Subjects.

Healthy Volunteers
Sidney Kimmel Comprehensive Cancer Center at Johns...
GlaxoSmithKline

Completed

Safety and Efficacy Study of I-131 Tositumomab in Patients With Relapsed/Refractory Hodgkin's Lymphoma

Hodgkin's Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Stage I-IIIB Non-Small Cell Lung Cancer After Completion of Radiation Therapy Alone or Combined Radiation Therapy and Chemotherapy

Lung Cancer

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Study of Tolerance, Biodistribution and Dosimetry of Fucoidan Radiolabeled by Technetium-99m (NANO-ATHERO)

Healthy Volunteer

France
Madrigal Pharmaceuticals, Inc.
Worldwide Clinical Trials

Completed

Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196

Healthy

United States
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
GlaxoSmithKline

Completed

Part A: Radiolabel Study With GW786034 Part B: Single Dose of GW786034

Carcinoma, Renal Cell

United States
GlaxoSmithKline

Completed

Study to Investigate the Absorption, Distribution, Metabolism and Elimination of [14C]GSK1120212

Cancer

United States
Cerus Corporation

Completed

A Controlled, In Vivo, Pilot Study to Assess the Recovery and Survival of Radiolabeled Autologous INTERCEPT Treated 7-Day Stored Apheresis Platelet Components in 35% Plasma and 65% InterSol and 7-Day Stored Apheresis Platelet Components in 100% Plasma

Healthy
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Immunoscintigraphy Using Radiolabeled Monoclonal Antibody in Finding Tumor Cells in Patients With Colorectal Cancer

Colorectal Cancer

United States
Celgene

Completed

Radiolabeled Study of CC-220 in Healthy Male Subjects

Healthy Volunteer

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Absorption, Metabolism, and Routes of Excretion Following Oral Administration of (14C) Radiolabeled JNJ--42756493 to Healthy Male Participants

Healthy

United States
The Cleveland Clinic

Terminated

TRACER RGD-K5 Carotid Plaque Imaging Study (TRACER)

Carotid Stenosis | Carotid Artery Disease

United States
GlaxoSmithKline

Completed

Study of Radiolabeled Monoclonal Antibody Anti-B1 for the Treatment of B-Cell Lymphomas and Extended Study to Determine the Safety and Efficacy of Coulter Clone® 131Iodine-B1 Radioimmunotherapy of Advanced Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin
Eli Lilly and Company

Completed

Disposition of 14C-LY3009104 Following Oral Administration in Healthy Human Subjects

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects

Arthritis

United States
Hoffmann-La Roche

Completed

A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers

Healthy Volunteer

Netherlands
Morphotek

Completed

A Single-Dose Pilot Study of Radiolabeled Amatuximab (MORAb-009) in Mesothelin Over Expressing Cancers

Pancreatic Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Liver Metastases | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Investigate the Absorption, Metabolism, and Excretion of Canagliflozin (JNJ-28431754) in Healthy Male Volunteers

Healthy

Belgium
Merck Sharp & Dohme LLC
Pfizer

Completed

A Radiolabeled Mass Balance Study of [14C]-Ertugliflozin (PF04971729, MK-8835) In Healthy Male Participants (MK-8835-038)

Type 2 Diabetes Mellitus (T2DM)
Cerus Corporation

Completed

A Study to Assess the Recovery and Lifespan of Radiolabeled Autologous S303 Treated Red Blood Cells (S303 RBC)

Focus: Assess Post Infusion Viability of S303 RBCs

United States
Trevena Inc.

Completed

A Study to Investigate the Metabolism and Excretion of [14C]-TRV130 in Healthy Male Subjects

Healthy

United States
Repros Therapeutics Inc.
Celerion

Completed

An Open-Label, Single-Dose Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of Radiolabeled Androxal in Healthy Male Subjects After Oral Administration

Secondary Hypogonadism

United States
Janssen Research & Development, LLC

Completed

A Study to Determine the Absorption, Metabolism, and Routes of Excretion of (14C) Radiolabeled Ibrutinib in Healthy Male Participants

Healthy Participants

Belgium
Montreal Heart Institute

Completed

Phase-I Study of Radiolabeled DFH-12 (PulmoBind) for Molecular Imaging of the Pulmonary Circulation

Pulmonary Hypertension | Pulmonary Disease

Canada

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