Search clinical trials for: Rectum toxicity

Total 2798 results

University of Utah

Recruiting

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer (FACE)

Metastatic Colon Cancer | Metastatic Rectum Cancer

United States
Institut de cancérologie Strasbourg Europe

Completed

Effect of Irradiation Doses < 10 Gy and of Irradiated Bone Volume on the Variation of Blood Elements of the Complete Blood Count During and After Pelvic Irradiation (MIFADORESOL)

Vaginal Cancer | Prostate Carcinoma | Radiotherapy | Rectum Carcinoma | Cervix Carcinoma | Anal Canal Carcinoma | Endometrium Carcinoma

France
Rabin Medical Center

Completed

IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.

Rectal Cancer | Toxicity Due to Radiotherapy | Radiotherapy

Israel
G1 Therapeutics, Inc.

Terminated

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC): (PRESERVE1)

Colorectal Cancer Metastatic | Chemotherapeutic Toxicity | Myelosuppression-Adult

China, Spain, United States, Hungary, United Kingdom, Poland, Ukraine, Italy
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride

Colorectal Cancer | Lung Cancer | Dermatologic Complications | Therapy-related Toxicity

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

Colorectal Cancer | Neurotoxicity | Neuropathy | Chemotherapeutic Agent Toxicity

United States, Puerto Rico
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan

Diarrhea | Colorectal Cancer | Chemotherapeutic Agent Toxicity

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Terminated

Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Jong Hoon Lee

Unknown

Two-week Course Versus Conventionally Fractionated Chemoradiotherapy in Rectal Cancer

Recurrence | Toxicity | Response to Toxin

Korea, Republic of
University of Illinois College of Medicine at Peoria

Unknown

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Pain, Postoperative | Constipation | Colon Cancer | Colonic Neoplasms | Ileus | Rectum Cancer | Constipation Drug Induced | Rectum Neoplasm | Colonic Diverticulitis | Ileus Paralytic | Colon Diverticulosis | Ileus; Mechanical

United States
Hospices Civils de Lyon

Unknown

Hyaluronic Acid for Hypofractionated Prostate Radiotherapy (RPAH1)

Prostate Cancer

France
University of Pittsburgh
Genentech, Inc.

Completed

Safety and Efficacy Study Using Bevacizumab, Capecitabine and Oxaliplatin for Colorectal Cancer

Cancer

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer (GRACE)

Rectal Neoplasms
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Pfizer

Terminated

Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal Cancer

Pain | Breast Cancer | Colorectal Cancer

United States, Puerto Rico
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
National Cancer Institute (NCI)

Completed

Amifostine to Protect the Rectum During External Beam Radiotherapy for Prostate Cancer

Prostatic Neoplasms

United States
Royal Marsden NHS Foundation Trust

Unknown

Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer

Sarcoma | Cervical Cancer | Testicular Germ Cell Tumor | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Cancer | Gastrointestinal Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United Kingdom
Institut Cancerologie de l'Ouest

Unknown

Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin

Colorectal Cancer | Neurotoxicity | Chemotherapeutic Agent Toxicity

France
European Institute of Oncology

Recruiting

Characterization of Biophysical and Mechanical Parameters on Skin of Breast Cancer Patients

Breast Cancer | Estrogen Receptor Positive Tumor

Italy
Tuen Mun Hospital

Not yet recruiting

Romosozumab Versus Denosumab in GIOP: a 2-year Extension Study

Osteoporosis | Glucocorticoids Toxicity

China
European Organisation for Research and Treatment...

Not yet recruiting

OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT) (SPRINT)

Breast Cancer | Colorectal Cancer | NSCLC | Prostate Cancer | Oligometastatic Disease
Fudan University

Recruiting

Short-course Radiotherapy Combined With CAPOX and PD-1 Antibody Versus Long-course Chemoradiotherapy Combined With CAPOX for Early Low-lying Rectal Cancer (TORCH-E2)

Early Low Rectal Cancer

China
Taipei Veterans General Hospital, Taiwan
National Yang Ming Chiao Tung University

Recruiting

Exploring Physical and Psychological Needs and Quality of Life in Patients With Advanced Cancer Receiving Immunotherapy

Quality of Life | Cancer | Immunotherapy | Distress, Emotional | Financial Toxicity | IrAE | Care Need

Taiwan
Akamis Bio

Not yet recruiting

NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer (FORTRESS)

Locally Advanced Rectal Cancer (LARC)
Jules Bordet Institute

Not yet recruiting

Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers (PILLAR)

Pelvic Cancer | Rectum Cancer
Fudan University

Recruiting

Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)

Rectal Cancer

China
Amsterdam UMC, location VUmc
Borstkanker Onderzoek Groep; Comprehensive Cancer Centre The Netherlands; Dutch...

Recruiting

Postoperative Re-irradiaTion With and Without HYPERthermia: Toxicity, Quality of Life and Survival in Patients With Locoregional Recurrent Breast Cancer (RT-HYPE)

Breast Cancer | Hyperthermia | Locoregional Recurrence | Re-irradiation

Netherlands
Klaus Gottlob Müller
Novo Nordisk A/S; Independent Research Fund Denmark

Not yet recruiting

Semaglutide in Auto-HSCT (PROTECT)

Inflammation | Chemotherapeutic Toxicity | Intestinal Mucositis
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

PeLear CCC: Proyecto Latino Contra Cancer Colorectal (PeLear CCC)

Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Colon Adenocarcinoma | Colon Rectal Cancer | Hereditary Nonpolyposis Colon Cancer

United States
Noordwest Ziekenhuisgroep
Borstkanker Onderzoek Groep; Comprehensive Cancer Centre The Netherlands; Dutch... and other collaborators

Not yet recruiting

Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects (eChemoCoach)

Breast Cancer | eHealth | Self Management | Symptom Monitoring
Odense University Hospital

Recruiting

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Quality of Life | Pleural Carcinomatosis | Chemotherapy Effect | Pleural Neoplasms | Chemotherapeutic Toxicity | Malignant Pleural Effusion | Pleural Cavity Effusion

Denmark
Nantes University Hospital

Not yet recruiting

Evaluation of a Range of Dermo-cosmetic Products to Treat Skin and Nail Toxicity Linked to Bispecific Anti-GPRC5D Bispecific Antibodies in Multiple Myeloma Patients". Myeloma". Descriptive Pilot Study (DELICATESSE)

Myeloma Multiple
Institut de cancérologie Strasbourg Europe
Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Recruiting

Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer (TNBC-RT2023)

Triple-negative Breast Cancer

France
Royal Marsden NHS Foundation Trust

Not yet recruiting

LATe TreatmENT Related Toxicity in Melanoma (LATENT) (LATENT)

Melanoma

United Kingdom
IRCCS San Raffaele

Recruiting

Non-invasive Assessment of RECTUM (POUCH) by US (RECT-US) in a Cohort of IBD Patients (RECT-US)

Crohn's Disease | Ulcerative Colitis

Italy
National Cancer Institute (NCI)

Not yet recruiting

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Carcinoma, Neuroendocrine | Tumor, Neuroendocrine | Tumors, Neuroendocrine | Neuroendocrine; Carcinoma | Small Cell; Receptors

United States
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium (RIVA-AP)

Anticholinergic Toxicity

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy (EROS3)

Locally Advanced Cervical Carcinoma
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
First Affiliated Hospital of Chengdu Medical College

Recruiting

Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis

Esophageal Cancer | Esophagitis | Radiation Toxicity

China
Assiut University

Not yet recruiting

Interventions for the Management of Perineal Cancer Pain

Cancer Rectum | Cancer Vulva | Cancer Vagina
Fudan University
Shanghai Zhongshan Hospital; RenJi Hospital; First Hospital of China Medical... and other collaborators

Not yet recruiting

Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study

Rectal Cancer | RECTAL NEOPLASMS
Universitair Ziekenhuis Brussel
University Ghent; Vrije Universiteit Brussel

Not yet recruiting

Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition. (PABTOX)

Breast Cancer | Body Weight | Chemotherapeutic Toxicity | Physical Inactivity | Chemotherapeutic Agent Toxicity | Paclitaxel Adverse Reaction

Belgium
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Assiut University

Not yet recruiting

Livertoxcicity in Acute Leukemia Patients During Chemotherapy Treatment

Liver Toxicity, Chemically-Induced
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine for Antimuscarinic Delirium (RIVA-AM)

Anticholinergic Toxicity

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Not yet recruiting

Personalization of Breast Radiotherapy According to Loco-regional Recurrence Risk and Toxicity Probability (PROBA)

Breast Cancer

France
Jing-kun Liu

Not yet recruiting

Correlation Between Gut Microbiota and Radiosensitivity of Rectal Cancer (GMRSC-LARC)

Locally Advanced Rectal Cancer
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy

Search clinical trials for: Rectum toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations