Search clinical trials for: Renal Safety

Total 59243 results

Chong Kun Dang Pharmaceutical

Recruiting

Efficacy and Safety of Telmisartan Compared With Losartan

Hypertension | Diabetic Nephropathies

Korea, Republic of
Atara Biotherapeutics

Not yet recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Lupus Nephritis

Systemic Lupus Erythematosus | Lupus Nephritis
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Enyo Pharma

Not yet recruiting

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1) (ALPESTRIA-1)

Alport Syndrome

Spain, United States, France, Germany
Q32 Bio Inc.

Not yet recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

IgA Nephropathy | Lupus Nephritis (LN) | C3 (Complement Component 3) Glomerulopathy
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in Adults With Type 2 Diabetic Kidney Disease

Type 2 Diabetic Kidney Disease
Air Force Military Medical University, China
First Affiliated Hospital Xi'an Jiaotong University; Shaanxi Provincial People... and other collaborators

Not yet recruiting

Efficacy and Safety of Tacrolimus in Combination With Ripertamab in the Initial Treatment of Patients With MCD

Minimal Change Disease
Norroy Bioscience Co., LTD

Recruiting

Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM005 in Patients

Clear Cell Renal Cell Carcinoma Metastatic

China
Shanghai Hutchison Pharmaceuticals Limited

Recruiting

Efficacy and Safety of Shenqi Sherong Pill in Participants With Cervical Spondylotic Myelopathy

Cervical Spondylotic Myelopathy

China
B.Braun Avitum AG

Recruiting

Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis

Renal Dialysis

Italy
Sun Yat-sen University

Not yet recruiting

A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery

Rectal Cancer | Renal Cancer | Liver Cancer

China
Leiden University Medical Center
AstraZeneca

Not yet recruiting

Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4 (LIBRAL)

Diet Modification | Chronic Kidney Disease | Hyperkalemia | Sodium Zirconium Cyclosilicate
AstraZeneca

Recruiting

Efficacy, Safety and Tolerability of Balcinrenone/Dapagliflozin Compared to Dapagliflozin in Adults With Chronic Kidney Disease. (MIRO-CKD)

Chronic Kidney Disease

Spain, Italy, China, Vietnam, United States, Brazil, Canada, Malaysia, Poland, Taiwan, Austria, Bulgaria, Chile, United Kingdom, Japan
RenJi Hospital

Recruiting

Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease

Obesity | Chronic Kidney Diseases

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States
Steno Diabetes Center Copenhagen
Rigshospitalet, Denmark

Recruiting

Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Hemodialysis | Peritoneal Dialysis | Chronic Kidney Disease | Dialysis

Denmark
EyeD Pharma

Recruiting

Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucoma

Primary Open-angle Glaucoma

Germany, Belgium
UMC Utrecht
Health Holland; Dutch Kidney Foundation; Servicio Madrileno De Salud (SERMAS); European... and other collaborators

Recruiting

First-in-human Study to Examine Safety of a New Peritoneal Dialysis Device (WEAKID) in End-stage Kidney Disease Patients (CORDIAL)

Chronic Kidney Diseases | Renal Insufficiency, Chronic | Kidney Failure, Chronic

Netherlands, Italy, Spain
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Pregnancy | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Atypical Hemolytic Uremic Syndrome (aHUS) | Ultomiris-exposed Pregnant/ Postpartum | Generalized Myasthenia Gravis (gMG) | Neuromyelitis Optica Spectrum Disorder (NMOSD)
First Affiliated Hospital of Harbin Medical University

Recruiting

Effectiveness and Safety of Finerenone in Chinese CKD Patients Without Diabetes Mellitus

Chronic Kidney Diseases

China
University Hospital, Rouen

Not yet recruiting

Safety of RotigotiNe in Patients With Autosomal Dominant Polycystic Kidney Disease (ETERNAL-PKD)

Kidney Diseases
Mahidol University

Not yet recruiting

Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL

Safety Issues | Surgery-Complications | Nephrolithiasis Staghorn Calculus

Thailand
Inozyme Pharma

Recruiting

The SEAPORT 1 Study: Evaluation of the Safety and Tolerability of INZ-701 in Adults With End-Stage Kidney Disease Undergoing Hemodialysis

Calciphylaxis

United States
AstraZeneca

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

Chronic Kidney Disease and Hypertension

Spain, United States, Argentina, Denmark, Italy, Sweden, United Kingdom, Belgium, France, Turkey, China, Germany, Saudi Arabia, Thailand, Vietnam, Australia, Serbia, Brazil, Canada, Japan, Malaysia, Philippines, Poland, Taiwan, Greece, Is... and more
River 2 Renal Corp.
International HealthCare, LLC

Not yet recruiting

To Evaluate the Safety, Tolerability and Efficacy of R2R01 Combined With SOC as Compared to SOC Alone in Outpatients With Worsening Heart Failure (WHF)

Heart Failure | Worsening Heart Failure (WHF)

United States
Ceric Sàrl
Electroducer

Not yet recruiting

Feasibility Study Evaluating the Safety and Efficacy of the Renal Stimulation by Direct Wire Pacing, During Renal Denervation Procedure (RNS by DWP)

Essential Hypertension
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical Trial

Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-1780 Tablets and Henagliflozin Proline Tablets in Patients With Chronic Kidney Disease

Chronic Kidney Disease
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Safety and Efficacy of TT-00420 Tablets Combined With Toripalimab Injection in Advanced Urological Tumors

Urothelial Carcinoma | Metastatic Castration-resistant Prostate Cancer | Clear Cell Renal Carcinoma

China
State University of New York at Buffalo

Not yet recruiting

Study to Evaluate the Safety and Efficacy of Bicalutamide in Combination With Sunitinib in Patients With TKIs-resistant RCC

Carcinoma, Renal Cell
Peking University Cancer Hospital & Institute

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Immunotherapy With Axitinib in Advanced Collecting Duct Carcinoma

Collecting Duct Carcinoma

China
Omeros Corporation

Recruiting

Safety and Efficacy Study of OMS906 in Patients With C3G and ICGN

C3 Glomerulopathy | Idiopathic Immune Complex-Mediated Glomerulonephritis

Lithuania, New Zealand, Poland, Tunisia, Turkey, United Kingdom
Yi Han
Qianfoshan Hospital

Recruiting

Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Heart Failure | Efficacy | Safety | Levosimendan | Milrinone

China
Kyowa Kirin Korea Co., Ltd.

Recruiting

Post Marketing Surveillance Study to Observe Safety and Effectiveness of CRYSVITA® in S. Korean Patients

FGF23-related Hypophosphataemic Rickets and Osteomalacia

Korea, Republic of
Ruijin Hospital

Recruiting

A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Urological Surgeries (SPiM-RWS-URO)

Urological Surgeries

China
AbbVie

Recruiting

A Study to Assess the Safety, Pharmacokinetics, and Efficacy of Intravenous (IV) ABBV-303, as Monotherapy and in Combination With IV Infused Budigalimab (ABBV-181), in Adults With Advanced Solid Tumors

Solid Tumors

United States, Israel
Qpex Biopharma, Inc.
Shionogi Inc.; Biomedical Advanced Research and Development Authority

Not yet recruiting

PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

Bacterial Infections
Wuhan Union Hospital, China
Yichang Humanwell Pharmaceutical Co., Ltd., China

Recruiting

PK/PD Properties and Safety of Remazolam Besylate for Injection in ICU Patients With Impaired Renal Function

Mechanically Ventilated Patients

China
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Hypertension

United States, Italy, Germany, Australia, Canada, United Kingdom, Puerto Rico, Bulgaria, Spain
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

Chronic Kidney Disease

United States
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Pharmacokinetic and Safety Studies of HRS-7535 in Subjects With Moderate Renal Insufficiency and Healthy Subjects

Type 2 Diabetes
Boryung Pharmaceutical Co., Ltd

Recruiting

A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.

Secondary Hyperparathyroidism | Chronic Kidney Disease 5D

Korea, Republic of
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
Ain Shams University

Not yet recruiting

Assessment of Safety and Efficacy of SGLT2is Among LN Patients

Lupus Nephritis

Egypt
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Renal Function

COVID-19 Pneumonia

China
AstraZeneca

Recruiting

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

Chronic Kidney Disease With High Proteinuria

Italy, United States, Poland, Germany, Argentina, Denmark, Norway, Spain, Sweden, Bulgaria, France, China, Taiwan, Thailand, Vietnam, Brazil, Japan, Malaysia, Mexico, Philippines, Israel, United Kingdom, South Africa, Austria, Korea, Republic... and more
EHL Bio Co., Ltd.

Recruiting

Safety and Efficacy of KDSTEM Inj. in Patients With Chronic Kidney Disease

Chronic Kidney Diseases

Korea, Republic of
Neonc Technologies, Inc.

Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Gastroesophageal Junction... and other conditions

United States
Inozyme Pharma

Recruiting

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/Phosphodiesterase1 Deficiency

United States, United Kingdom, Canada
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Safety and Pharmacokinetics of HRS-1780 in Healthy Subjects and Subjects With Impaired Renal Function

Chronic Kidney Disease

Search clinical trials for: Renal Safety

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