Search clinical trials for: Response to radiation therapy

Total 475834 results

City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

Breast Carcinoma | Colorectal Carcinoma

United States
University of Oklahoma

Not yet recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Androgen Deprivation Therapy | Locally Advanced Prostate Cancer

United States
Vanderbilt-Ingram Cancer Center
Genentech, Inc.

Recruiting

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation (TESSERACT)

Stage IV Lung Cancer | Extensive Stage Lung Small Cell Carcinoma

United States
M.D. Anderson Cancer Center

Recruiting

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma

Lymphoma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States, Puerto Rico
University of Zurich

Recruiting

Response Assessment During MR-guided Radiation Therapy for Glioblastoma (MARGA)

Glioblastoma Multiforme

Switzerland
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas

Soft Tissue Sarcoma | Recurrent Soft Tissue Sarcoma | Resectable Soft Tissue Sarcoma

United States
Jena University Hospital

Recruiting

Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer (PRIMO)

Radiotherapy | Neoadjuvant Treatment | Locally Advanced Rectal Carcinoma | Adaptive Treatment

Germany
Erasmus Medical Center

Recruiting

Biomarker Identification of Radionuclide Therapy-induced Radiation Responses (Radio-Marker)

Neuroendocrine Tumors

Netherlands
Stephen Shiao
Merck Sharp & Dohme LLC; Incyte Corporation

Recruiting

Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation

Breast Cancer | TNBC - Triple-Negative Breast Cancer

United States
University of Wisconsin, Madison

Recruiting

Imaging and Genomic Biomarkers to Predict Response in Prostate Cancer

Prostate Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

Lymphoma | Metastatic Malignant Solid Neoplasm

United States
University of Virginia

Recruiting

Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer (Breast53)

Breast Cancer | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III

United States
University of Michigan Rogel Cancer Center

Recruiting

Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)

Metastatic Melanoma | Liver Metastases | Melanoma, Mucosal | Melanoma, Ocular | Melanoma, Cutaneous

United States
National Cancer Institute (NCI)

Recruiting

18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

Localized Prostate Cancer

United States
Sheba Medical Center
Bristol-Myers Squibb

Recruiting

Maintenance Ipilimumab + Nivolumab Post Induction Chemotherapy + SBRT for First Line Treatment Stage IV Pancreatic Cancer

Stage IV Pancreatic Cancer

Israel
University of Texas Southwestern Medical Center

Recruiting

'Re-Priming' RT After Incomplete Response to CAR-T in R/R NHL

Non-Hodgkin Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

Thyroid Gland Carcinoma

United States
Lawson Health Research Institute

Recruiting

Three Fraction Radiation to Induce Immuno-Oncologic Response (TRIO)

Locally Advanced Breast Cancer | High-Risk Cancer

Canada
Institut Paoli-Calmettes
University of California, Los Angeles

Recruiting

Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems (DWI_RECT_MRGRT)

Rectal Adenocarcinoma

France, United States
St. Jude Children's Research Hospital
Seagen Inc.; Teva Pharmaceuticals USA

Recruiting

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

Hodgkin Lymphoma

United States
Hospital JP Garrahan
Hospital Pereyra Rosell, Montevideo, Uruguay

Recruiting

Pediatric Hodgkin Lymphoma Treatment Trial With Low Cumulative Doses of Chemotherapy Agents and Reduced Radiation. (LHGALOP2017)

Pediatric Hodgkin's Disease

Argentina
Memorial Sloan Kettering Cancer Center

Recruiting

Imaging Acquisition and Analysis Methods for Optimization of MRI Radiation Oncology Simulation and Response Assessment

Radiation Therapy

United States
National Cancer Institute (NCI)

Recruiting

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

Prostatic Neoplasms | Prostate Cancer

United States
Case Comprehensive Cancer Center

Completed

Magnetic Resonance Guided Focal Stereotactic Body Radiation Therapy for Localized Prostate Cancer

Recurrent Prostate Cancer | Stage I Prostate Cancer | Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
Parker Institute for Cancer Immunotherapy
Bristol-Myers Squibb; Cancer Research Institute, New York City; Celldex Therapeutics and other collaborators

Completed

Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations (PORTER)

Metastatic Castration-resistant Prostate Cancer

United States
Washington University School of Medicine

Active, not recruiting

Non-Operative Management and Early Response Assessment in Rectal Cancer (NOM-ERA)

Adenocarcinoma of the Lower Rectum

United States
Memorial Sloan Kettering Cancer Center
Cedars-Sinai Medical Center

Completed

Homologous Recombination Repair Status as a Biomarker of Response in Locally Recurrent/Metastatic Triple Negative Breast Cancer Patients Treated With Concurrent Cisplatin and Radiation Therapy

Locally Recurrent/Metastatic Triple Negative Breast Cancer

United States
Ali Shamseddine
Merck KGaA, Darmstadt, Germany; Phoenix Clinical Research

Active, not recruiting

Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma

Locally Advanced Rectal Cancer

Lebanon, Jordan
Stanford University

Completed

CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy

Stage IV Lung Cancer | Metastatic Malignant Neoplasm in the Lung | Non-Small Cell Lung Carcinoma | Malignant Lung Neoplasm

United States
European Organisation for Research and Treatment...

Active, not recruiting

Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study (COBRA)

Advanced Hodgkin Lymphoma

Belgium, Spain, Netherlands, Denmark, Poland, Portugal, Slovakia
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Acute Myeloid Leukemia | Down Syndrome | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myeloid Leukemia Associated With Down Syndrome

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery

Glioblastoma

United States
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer (OPTIMA)

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
University of Michigan Rogel Cancer Center

Completed

A Pilot Study of Response-Driven Adaptive Radiation Therapy for Patients With Locally Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Memorial Sloan Kettering Cancer Center
Bayer

Active, not recruiting

Metastatic Spinal Bone Marrow Response to Radiation Therapy Using T1 Weighted Dynamic Contrast-Enhanced Perfusion

Solid Cancer | Metastatic Spinal Lesions

United States
Institut Paoli-Calmettes

Active, not recruiting

Histological Response Rate After Mastectomy and Immediate Breast Reconstruction at the End of Neoadjuvant Chemotherapy and Radiotherapy (HIST-RIC)

Breast Cancer

France
National Institutes of Health Clinical Center (CC)
Inova Fairfax Hospital

Completed

The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Interstitial Pneumonitis | Desquamative Interstitial Pneumonia

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer (COXEN)

Bladder Cancer

United States
Emory University
Johns Hopkins University; National Cancer Institute (NCI); National Institute... and other collaborators

Active, not recruiting

MRSI to Predict Response to RT/TMZ ± Belinostat in GBM

Glioblastoma Multiforme of Brain

United States
West Virginia University
West Virginia Clinical and Translational Science Institute

Completed

Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer Metastatic

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy

Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Maastricht Radiation Oncology
Maastricht University Medical Center; The Netherlands Cancer Institute; Zuyderland...

Completed

Re-Induction After Initial Response With Immune Therapy With Radiotherapy in Lung Cancer

Non-Small Cell Carcinoma of Lung, TNM Stage 4

Netherlands
Aziende Chimiche Riunite Angelini Francesco S.p.A
PPD

Completed

Benzydamine Oromucosal Solution in Oral Mucositis (BOOM) (BOOM)

Head and Neck Cancer | Radiation-Induced Mucositis

Hungary, Poland
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery

Bladder Cancer

United States, Canada
Fundacion GenesisCare
Hospital La Milagrosa; Hospital Vithas Valencia Consuelo

Suspended

Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 (ULTRA-COVID)

Pneumonia, Viral | Cytokine Storm

Spain
National Cancer Institute (NCI)

Terminated

Predictors of Tumor Response and of Radiation Therapy Side Effects in Patients With Gastrointestinal Cancers

Stomach Cancer | Pancreatic Cancer | Esophageal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Response-Based Therapy Assessed By PET Scan in Treating Patients With Bulky Stage I and Stage II Classical Hodgkin Lymphoma

Lymphoma

United States
NYU Langone Health
National Cancer Institute (NCI)

Completed

Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases

Breast Cancer | Metastatic Breast Cancer | Recurrent Breast Cancer

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

The Antiplatelet and Immune Response Trial

Healthy

United Kingdom

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