Search clinical trials for: SIM1 deficiency obesity

Total 21916 results

Soleno Therapeutics, Inc.

Not yet recruiting

An Open-Label Study of Diazoxide Choline in Patients With Genetic Obesities

SH2B1 Deficiency Obesity | Obesity Associated With PCSK1 Mutation (rs6232 Variant) | SIM1 Deficiency Obesity
University of Ulster
Northern Health & Social Care Trust (NHSCT); Solvotrin Therapeutics - Active...

Not yet recruiting

Adiposity and Iron Requirements in Pregnancy (ADIPREG)

Iron Deficiency Anemia of Pregnancy

United Kingdom
German Federal Institute for Risk Assessment
University of Vienna; Heidelberg University; University of Jena; University of... and other collaborators

Not yet recruiting

Cohort Study on Plant-based Diets (COPLANT Study) (COPLANT)

Cardiovascular Diseases | Obesity | Diabetes Mellitus, Type 2 | Bone Loss | Dietary Exposure | Sustainability | Vitamin Deficiency | Mineral Deficiency | Exposure

Germany, Austria
Rolfs Consulting und Verwaltungs-GmbH (RCV)
Rhythm Pharmaceuticals, Inc.

Recruiting

Early Genetic Identification of Obesity (WEGIO)

Cognitive Impairment | Hyperphagia | Obesity, Childhood | Bardet-Biedl Syndrome | Polydactyly | Retinopathy | Syndactyly | POMC Deficiency

Germany
Instituto Nacional de Ciencias Medicas y Nutricion...

Not yet recruiting

Effect of Weight Loss on Hepcidin Levels and Iron Status in Subjects With Obesity.

Obesity | Iron Deficiency Anemia
Brigham and Women's Hospital
Charles A. King Trust Postdoctoral Fellowship Program

Not yet recruiting

Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

Overweight and Obesity
LG Chem

Not yet recruiting

A Phase 2 Study to Assess Efficacy and Safety of LB54640 in Patients With Genetic Obesity

POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

France, United Kingdom
Royal College of Surgeons, Ireland
Steroid Metabolism Analysis Core, University of Birmingham; Institute of Systems...

Not yet recruiting

Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance in Men (MMetdMH)

Cardiovascular Diseases | Obesity | Diabetes | Metabolic Syndrome | Prostate Cancer | NAFLD | Metabolic Disturbance | Metabolic Disease | Hypogonadism, Male | Testosterone Deficiency | Androgen Deficiency

Ireland
Hospital Universitario Pedro Ernesto
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Rio de Janeiro...

Recruiting

Vitamins D and K Effects on Vascular Function in Obese Adults.

Obesity | Vitamin D3 Deficiency

Brazil
Rutgers, The State University of New Jersey

Recruiting

IVIG vs SCIG in CIDP

Chronic Inflammatory Demyelinating Polyneuropathy | CIDP | Immunoglobulin Deficiency

United States
Rare Thyroid Therapeutics International AB
Premier Research Group plc; Egetis Therapeutics

Recruiting

Withdrawal of Tiratricol Treatment in Males With Monocarboxylate Transporter 8 Deficiency (MCT8 Deficiency) (ReTRIACt)

Monocarboxylate Transporter 8 Deficiency | Allan-Herndon-Dudley Syndrome

United States, United Kingdom, Netherlands
East Carolina University
Janssen Scientific Affairs, LLC

Recruiting

Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain

HIV Infections | Obesity

United States
Hospital Infantil de Mexico Federico Gomez

Recruiting

Effects of Vitamin D Supplementation in Adolescents With Asthma, Obesity and Vitamin D Deficiency.

Obesity | Vitamin D Deficiency | Non-allergic Asthma

Mexico
Cairo University

Recruiting

Effect of Aerobic Exercise and Diet on Anthropometric and Hematological Measurements in Obese Anemic Women

Obesity | Iron Deficiency Anemia

Egypt
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil (AVERTAS-2)

HIV Infections | Obesity | Renal Insufficiency | Osteoporosis | Hiv | Weight Gain | HIV Lipodystrophy

Denmark
Fundació Institut de Recerca de l'Hospital de la...
Instituto de Salud Carlos III

Recruiting

Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)

Pituitary Diseases | Hypothalamic Diseases | Hypopituitarism | Social Isolation | Panhypopituitarism | Psychological Disorder | Central Diabetes Insipidus | Oxytocin Deficiency

Spain
Rutgers, The State University of New Jersey

Recruiting

Immunoglobulin G Therapy Dose Optimization

Obesity | Immune Deficiency

United States
Singapore General Hospital
Baylor College of Medicine; National University Health System, Singapore

Recruiting

Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity

Morbid Obesity | Glycine; Metabolic Disorder

Singapore
University Of Perugia

Recruiting

Metabolic Effects of Very Low Carbohydrate Ketogenic Diet in Subjects With Severe Obesity

Obesity | Ketosis | Lysosomal Acid Lipase Deficiency | Ketogenic Dieting

Italy
Hospices Civils de Lyon

Not yet recruiting

Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents (Obevidos)

Obesity, Childhood
Azienda Ospedaliero Universitaria Maggiore della...

Recruiting

ZIMBA: Clinical Trial in Paediatric Obesity (ZIMBA)

Insulin Resistance | Zinc Deficiency | Obesity, Childhood | Inositol

Italy
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Medical University of Graz
Technical University of Munich; Paracelsus Medical University; University of... and other collaborators

Recruiting

Observational Study of Early Metabolic and Vascular Changes in Obesity (STYJOBS)

Inflammation | Obesity | Atherosclerosis | Fatty Liver | Adiponectin Deficiency

Austria
Indonesia University
Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia

Completed

Nutrition, Immunity, and Covid-19 in Obese People (NICO)

Covid19 | Vitamin D Deficiency | Overweight and Obesity | Immune Deficiency

Indonesia
Hoskinson Health and Wellness Clinic
University of Wyoming; Buck Institute for Research on Aging

Active, not recruiting

Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity

Depression | Cardiovascular Diseases | Inflammation | Hypertension | Obesity | Cognitive Impairment | Insulin Resistance | Hyperlipidemias | Physical Disability | Physical Inactivity | Hormone Deficiency | Overeating

United States
Rare Thyroid Therapeutics International AB
Erasmus Medical Center

Active, not recruiting

Triac Trial II in MCT8 Deficiency Patients

Allan-Herndon-Dudley Syndrome

United States, Netherlands, Czechia, Germany
Rare Thyroid Therapeutics International AB
Egetis Therapeutics; AnovoRx

Available

Expanded Access Program for Tiratricol in Patients With Monocarboxylate Transporter 8 Deficiency

Monocarboxylate Transporter 8 Deficiency | Allan-Herndon-Dudley Syndrome

United States
Fundació Institut de Recerca de l'Hospital de la...

Completed

Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)

Hypopituitarism | Social Isolation | Pituitary Dysfunction | Hypothalamic Obesity | Central Diabetes Insipidus | Oxytocin Deficiency

Spain
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Al-Balqa Applied University
University of Jordan

Completed

High Fat vs High Protein and Appetite Hormones

Body Weight | Appetitive Behavior | Hormone Deficiency | Dietary Exposure

Jordan
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Completed

Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia (Harapan)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence
University of Illinois at Chicago
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Feasibility or Oral Lactoferrin to Prevent Iron Deficiency Anemia in Obese Pregnancy

Obesity | Iron-deficiency | Pregnancy Anemia

United States
Hospital Clinic of Barcelona
Institut Nacional d'Educacio Fisica de Catalunya; Garmin International

Completed

Effect of Protein Supplementation and a Structured Exercise Program on Muscle in Women After Bariatric Surgery. (SarcoFit)

Bariatric Surgery Candidate | Sarcopenic Obesity | Nutritional Deficiency | Protein Intolerance

Spain
OPKO Health, Inc.

Active, not recruiting

Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Pediatric Growth Hormone Deficiency

Israel, United States, India, Korea, Republic of, Australia, Taiwan, Spain, Argentina, Belarus, Bulgaria, Canada, Colombia, Georgia, Greece, Mexico, New Zealand, Poland, Russian Federation, Ukraine, United Kingdom
Fundación Cardiovascular de Colombia
Universidad Industrial de Santander; Farma de Colombia SA

Completed

Efficacy of Oral Vitamin D Supplementation in Adolescents and Young Adults. (SIMBAIII)

Vitamin D Deficiency | Overweight and Obesity | Overweight Adolescents

Colombia
Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Bioitalia srl

Completed

Multivitamin Support Following Bariatric Surgery

Bariatric Surgery

Italy
University of Trieste

Completed

Hypovitaminosis D and "Metabolic" Inflammatory Status in Patients With Obesity (ViDO)

Obesity | Hypovitaminosis D

Italy
Oregon Health and Science University

Completed

The Effects of Work Schedule and Sleep Patterns on Caregivers' Health

Obesity | Diabetes | Cancer | Metabolic Syndrome | Sleep Deprivation

United States
Regeneron Pharmaceuticals

Available

Expanded Access to REGN4461 for Patients With Lipodystrophy or Monogenic Obesity With Complications of Leptin Deficiency or Deficient Leptin Signaling

Partial Lipodystrophy | Generalized Lipodystrophy | Monogenic Obesity Due to LEP or LEPR Loss of Function
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Bardet-Biedl Syndrome | POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

United States, Australia, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Pro-opiomelanocortin (POMC) Deficiency Obesity

Belgium, United States, Canada, France, Germany, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Obesity | Genetic Obesity | Obesity Due to Melanocortin 4 Receptor Deficiency

United States, United Kingdom, Germany, Netherlands, France, Canada, Greece, Israel, Spain
University of Bath
University of Nottingham

Active, not recruiting

Physiological and Sensory Responses to Prolonged Fasting in Humans (PRO-FAST)

Adiposity | Metabolic Disturbance | Fasting | Energy Supply; Deficiency

United Kingdom
Augusta University

Completed

Contribution of Dolutegravir to Obesity and Cardiovascular Disease

Vascular Diseases | Body Weight Changes | Cardiovascular Abnormalities | HIV-1-infection | Body Fat Disorder | HIV-Associated Lipodystrophy Syndrome | Antiviral Drug Adverse Reaction | Abnormality of Adipose Tissue

United States
Vanderbilt University Medical Center

Active, not recruiting

Small Bowel Length and Bariatric Surgery Outcomes

Obesity | Malnutrition | Weight Loss | Micronutrient Deficiency

United States
Nutrition Institute, Slovenia
National Institute of Public Health, Slovenia; University Medical Centre Ljubljana and other collaborators

Enrolling by invitation

Dietary Challenges in the Population of Nursing Homes' Residents (NUTRICARE)

Obesity | Iron-deficiency | Vitamin D Deficiency | Nutritional Status | Sarcopenia | Vitamin B 12 Deficiency | Folic Acid Deficiency | Diet | Nutrient Deficiency | Micronutrient Deficiency | Protein Deficiency

Slovenia
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
Prism Health North Texas
Merck Sharp & Dohme LLC

Withdrawn

Doravirine and Weight Gain in Antiretroviral Naive (DAWN)

Obesity | Metabolic Syndrome | Body Weight Changes | Human Immunodeficiency Virus | Fasting | Minority Health | ART | BMD

United States
IDeA States Pediatric Clinical Trials Network
National Institutes of Health (NIH)

Completed

Vitamin D Oral Replacement in Asthma (VDORA1)

Vitamin D Deficiency | Asthma | Pediatric Obesity

United States

Search clinical trials for: SIM1 deficiency obesity

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