Search clinical trials for: Safety and efficacy

Total 472194 results

Spinogenix

Not yet recruiting

Safety, Tolerability, and Efficacy of SPG302 in Adult Participants With Mild-to-Moderate Alzheimer's Disease (AD)

Alzheimer Disease
SpliSense Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Humedix Co., Ltd.

Recruiting

Efficacy and Safety of HMM1-022 in Temporary Correction of Crow's Feet

Crows Feet

Korea, Republic of
Beijing Tiantan Hospital

Not yet recruiting

Efficacy and Safety of Chinese Herbal Formula HuoXue LiShui for Chronic Subdural Hematoma (CHARM)

Chronic Subdural Hematoma

China
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM

Gastric Cancer, Metastatic
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients

Dry Eye | Dry Eye Syndromes

Korea, Republic of
Luye Pharma Group Ltd.

Not yet recruiting

To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets

Major Depressive Disorder
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
Celgene

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (GOLSEEK-2)

Lymphoma, Follicular

United States, Australia, Brazil, Canada, Chile, France, Germany, Italy, Korea, Republic of, Poland, Spain, Taiwan, United Kingdom
Massachusetts Eye and Ear Infirmary

Not yet recruiting

The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy

Rhegmatogenous Retinal Detachment | Proliferative Vitreoretinopathy | Proliferative Vitreo-Retinopathy
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Aldeyra Therapeutics, Inc.

Recruiting

A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

United States
UCB Biopharma SRL

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis (BE TOGETHER)

Moderate to Severe Plaque Psoriasis
Enyo Pharma

Not yet recruiting

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1) (ALPESTRIA-1)

Alport Syndrome

Spain, United States, France, Germany
Highlight Therapeutics

Not yet recruiting

Clinical Trial to Evaluate Safety, Tolerability and Preliminary Efficacy of BO-112 in Patients With BCC (SPOTLIGHT204)

Basal Cell Carcinoma
Xintian Pharmaceutical

Not yet recruiting

Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules (ESPTTN)

Thyroid Nodule

China
AstraZeneca

Recruiting

MultIceNtre Non-intERVentional Study for Efficacy,Safety Evaluation of BREZTRI in Pts With COPD in RussiA (MINERVA)

Chronic Obstructive Pulmonary Disease

Russian Federation
European Institute of Oncology

Not yet recruiting

Efficacy and Safety of HILOTERM® Device for the Prevention of Peripheral Neuropathy

Breast Cancer | Neuropathy;Peripheral

Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs

Unresectable Gallbladder Cancer

China
Indiana University
Dreamland Baby Co.

Recruiting

Assessment of the Safety and Efficacy of Weighted Wearable Blankets in Healthy Infants During Sleep

Sleep

United States
Istituto Clinico Humanitas

Not yet recruiting

Efficacy and Safety of Oral Administration of Postibiotic by FOS Fermentation From Lactobacillus Paracasei in the Treatment of Irritable Bowel Syndrome. (prePO23)

IBS - Irritable Bowel Syndrome

Italy
Haisco Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of HSK16149 Capsule in the Treatment of Moderate and Severe Central Neuropathic Pain in China

Central Neuropathic Pain
GeneCradle Inc

Recruiting

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Spinal Muscular Atrophy Type 3

China
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
Qilu Hospital of Shandong University

Not yet recruiting

Evaluation of the Efficacy and Safety of Indocyanine Green Tracing in 3D Fluorescent Laparoscopic Lymph Node Dissection for Gastric Cancer

Gastric Cancer

China
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
University of Oxford
Oxford Brookes University; Oxford University Hospitals NHS Trust; Scholar Rock... and other collaborators

Not yet recruiting

Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA) (ACE SMA) (ACE SMA)

Spinal Muscular Atrophy

United Kingdom
89bio, Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Peking University People's Hospital
Xingtai People's Hospital; Hebei Provincial People's Hospital

Not yet recruiting

Efficacy and Safety of an Artificial-pancreas-like Learning-based Control in Type 1 Diabetes on Multiple Daily Injection Therapy (ELITE)

Diabetes Mellitus, Type 1
Shanghai Changzheng Hospital

Not yet recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients

Advanced Hepatocellular Carcinoma
Mannkind Corporation

Not yet recruiting

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension (ICoN-1)

Mycobacterium Infections, Nontuberculous | MAC Lung Disease | Treatment Refractory MAC Lung Disease

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma

Chloasma

China
Biohaven Therapeutics Ltd.

Not yet recruiting

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

Major Depressive Disorder
Anhui Provincial Hospital

Not yet recruiting

A Study on the Safety and Preliminary Efficacy of NK042 in the Treatment of Malignant Ascites

Gynecologic Cancer

China
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
AJU Pharm Co., Ltd.

Recruiting

Efficacy and Safety of AJU-C52 in Essential Hypertension Patients

Essential Hypertension

Korea, Republic of
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in Adults With Type 2 Diabetic Kidney Disease

Type 2 Diabetic Kidney Disease
Peking University First Hospital

Not yet recruiting

Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients

Type 2 Diabetes
NMD Pharma A/S

Not yet recruiting

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis (SYNAPSE-MG)

Myasthenia Gravis | Myasthenia Gravis, MuSK
AstraZeneca
Daiichi Sankyo

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung15)

Metastatic Non-small Cell Lung Cancer
Li Xiaorong
Shanghai Refreshgene Technology Co., Ltd.

Recruiting

The Preliminary Safety and Efficacy of RRG001 After Vitrectomy in Subjects With Proliferative Diabetic Retinopathy (PDR)

PDR - Proliferative Diabetic Retinopathy

China
GlaxoSmithKline

Not yet recruiting

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) (BE-EARLY)

Systemic Lupus Erythematosus
Suzhou Kerui Medical Technology Co., Ltd
Suzhou Mingshi Optical Technology Co., Ltd

Recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression

Myopia

China
xiaohua li

Not yet recruiting

Safety and Efficacy of Pembrolizumab in Combination With FLOT About Gastroesophageal Junction Cancer:

Gastroesophageal Junction Cancer
SamA Pharmaceutical Co., Ltd

Recruiting

The Efficacy and Safety of Atock Dry Syrup With Acute Bronchitis Patients

Acute Bronchitis

Korea, Republic of
Xuzhou Medical University

Not yet recruiting

Safety and Efficacy of Treg Cell in the Treatment of GVHD

GVHD
MoonLake Immunotherapeutics AG

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa
Medinol Ltd.

Not yet recruiting

First In Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients With Superficial Femoral Artery Disease and/or Proximal Popliteal Artery Disease (CHAMPIONSHIP)

Popliteal Artery Stenosis | Superficial Femoral Artery Stenosis

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