Search clinical trials for: Single nucleotide polymorphism

Total 9554 results

Boston Children's Hospital

Completed

A P2X7R Single Nucleotide Mutation Promotes Chronic Allograft Vasculopathy

Cardiac Allograft Vasculopathy

United States
University of California, Davis
National Institutes of Health (NIH)

Completed

Fish Oil to Prevent Asthma Exacerbations in Patients With ALOX5 Polymorphisms

Asthma

United States
Association HGE CHU Bordeaux Sud
University Hospital, Bordeaux

Completed

Predictive Factors of the Treatment Failure in Hepatitis C Virus (HCV) Infected Patients Treated With Telaprevir (GENUPI)

Chronic Hepatitis C

France
Instituto Dante Pazzanese de Cardiologia
University of Campinas, Brazil

Completed

Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis

Primary Prevention

Brazil
National Institute of Environmental Health Sciences...

Completed

Functional Implications of TNF

Bronchitis

United States
Mayo Clinic
Samuel C. Johnson Foundation

Completed

Acamprosate: Genes Associated With Response (ACAM)

Alcoholism

United States
In-Jin Jang, MD, PhD
Seoul National University Hospital; Kyushu University; Oita University

Completed

An Open-label, Single-dose, Two-treatment, Randomized, Cross-over Study to Investigate the Effects of the SLCO2B1 c.1457C>T Polymorphism and Apple Juice on the Pharmacokinetics and Pharmacodynamics of Acebutolol in Healthy Korean and Japanese Volunteers

Healthy

Korea, Republic of, Japan
Emory University
Children's Healthcare of Atlanta

Completed

Influence of Genetic Polymorphisms on Ventricular Structure and Function in Patients With Single Ventricle Anatomy

Congenital Heart Disease

United States
UConn Health
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

Alcoholism | Alcohol Related Disorders | Alcohol Abuse

United States
Columbia University
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

A Single Arm Clinical Trial Assessing the Maternal Outcome Monitoring Systems" (MOMS)

Pregnancy Related Death

United States
Tianjin Medical University Cancer Institute and...

Recruiting

The Safety and Effectiveness of NEPA in Preventing Postoperative Nausea and Vomiting After General Anesthesia Gastrointestinal Cancer Surgery: A Single-Center Retrospective Study

General Anesthesia Gastrointestinal Cancer Surgery

China
University of Jordan

Not yet recruiting

Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns

Dental Implant | Dental Restoration

Jordan
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
Beijing Tiantan Hospital

Recruiting

Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅳ(TRACE Ⅳ)

Minor Ischemic Stroke | Tenecteplase

China
Keymed Biosciences Co.Ltd

Not yet recruiting

Single Dose Escalation Study of CM383 in Healthy Volunteers

Alzheimer Disease
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Safety and Pharmacological Effect of a Single Intravenous Infusion of Belantamab in Male and Female Participants Aged 18 to 75 With Moderate to Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Huashan Hospital
Chinese Academy of Sciences

Not yet recruiting

A Study of the Higher Cognitive Functions of the Human Brain With Single-neuron Activity Recording

Cognition

China
Aliada Therapeutics

Not yet recruiting

A Phase 1 Trial to Assess Safety, Tolerability and Pharmacokinetics of ALIA-1758 in Healthy Participants

Alzheimer Disease

United States
University of Calgary

Recruiting

Evaluating the Impacts of a Single Session of Robot Assisted Gait Training With a Trexo

Physical Disability | Developmental Disability | CP (Cerebral Palsy)

Canada
Semmelweis University
Institut Straumann AG

Recruiting

Effect of Abutment Configuration on Peri-implant Soft and Hard Tissue in the Esthetic Zone - Randomized Clinical Trial

Dental Implant-Abutment Design | Dental Implants, Single-Tooth

Hungary
Shanghai Changzheng Hospital
CARsgen Therapeutics Co., Ltd.

Not yet recruiting

Study of CT071 Injection in HRNDMM

High-risk Newly Diagnosed Multiple Myeloma (HRNDMM)
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
Tianjin Medical University Cancer Institute and...

Recruiting

Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study

Pancreatic Cancer

China
Gazi University

Recruiting

Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects

Gingival Recession, Localized

Turkey
Hospital Nossa Senhora da Conceicao

Not yet recruiting

ARISCAT, ASA and LAS VEGAS Risk Scores and the Incidence of Postoperative Pulmonary Complications in Thoracic Surgery

Postoperative Complications
Tianjin Medical University Cancer Institute and...

Not yet recruiting

A Prospective, Single-arm, Multicenter Phase II Clinical Study of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Adebrelimab

China
Bayer

Not yet recruiting

A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Chronic Kidney Disease | Hepatic Impairment
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure

Heart Failure | Decompensated Heart Failure
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
Istituto Ortopedico Rizzoli

Not yet recruiting

Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis (BS23)

Scoliosis | Adolescent Idiopathic Scoliosis | Spine Deformity

Italy
Dongyang People's Hospital

Not yet recruiting

Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain

Myopia

China
Fudan University

Not yet recruiting

Active Surveillance for Single Ground-glass Opacities

Lung Ground-glass Opacities | Watchful Waiting
Peking University First Hospital

Recruiting

Establishment of a Multidimensional Prediction Model for the Natural Course of VHL Disease-related Renal Cell Carcinoma

Renal Cell Carcinoma | VHL Syndrome

China
Dong-A ST Co., Ltd.

Not yet recruiting

A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants

Healthy

Korea, Republic of
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

A Randomized, Double-blind,Dose-escalating, Single-dose, Oral Phase I Clinical Study of Flunotinib Healthy People

Healthy Person

China
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Single-arm Study of Nimotuzumab Combined With mFOLFIRNIOX as Postoperative Adjuvant Therapy in Pancreatic Cancer

Pancreatic Cancer

China
Suzhou Kerui Medical Technology Co., Ltd
2020 (Beijing) Medical Technology Co., Ltd

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Efficacy of Single-use Fibrous Ring Sutures for the Suture of Fibrous Ring Incision After Nucleus Pulposus Removal

Intervertebral Disc Disorder
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
University of Campania "Luigi Vanvitelli"
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; University of Milan and other collaborators

Recruiting

The PRO-FUTURE Project (PRO-FUTURE)

Chronic Kidney Diseases | Ureteropelvic Junction Obstruction

Italy
Nordsjaellands Hospital

Recruiting

Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block

Anesthesia, Local | Surgery | Brachial Plexus Block | Nerve Block | Forearm Fracture

Denmark
AstraZeneca
Parexel

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral AZD0233 Compared With Placebo in Healthy Adult Participants.

Dilated Cardiomyopathy

United States
The Methodist Hospital Research Institute

Recruiting

CBD for Pain Following Orthopedic Shoulder Surgery (CBD)

Rotator Cuff Injuries | Shoulder Osteoarthritis

United States
Nordsjaellands Hospital

Recruiting

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Colles' Fracture | Fracture Dislocation | Distal Radius Fractures | Lidocaine | Ropivacaine | Closed Reduction of Fracture and Application of Plaster Cast

Denmark
Orthopaedic Education and Research Institute (dba...
Irrimax Corporation

Recruiting

Wound Irrigation Comparative Effectiveness Study

Cutibacterium Acnes Contamination

United States
Guangzhou Medical University
Ningbo SensCure Biotechnology Co., Ltd.

Recruiting

Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Cough (ColdCough)

Chronic Cough

China
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany

Search clinical trials for: Single nucleotide polymorphism

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