Search clinical trials for: Single Ascending Dose Study in healthy subjects

Total 466215 results

Kylonova (Xiamen) Biopharma co., LTD.

Not yet recruiting

Single-ascending Dose Study of Kylo-11 in Healthy Subjects

Cardiovascular Diseases

China
BeiGene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035

Autoimmune Diseases | Healthy Volunteers | Healthy Subjects | Healthy Participants | Healthy Adult Participants
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Almirall, S.A.

Recruiting

A Single and Multiple Ascending Dose Study of LAD603 in Healthy Subjects

Healthy Volunteers

United States
IlDong Pharmaceutical Co Ltd
YUNOVIA CO.,LTD.

Recruiting

Single Ascending Oral Dose Phase 1 Study of ID110521156 in Healthy Adult Subjects

Healthy Adult Subjects

Korea, Republic of
Arxx Therapeutics

Recruiting

A First in Human Study of AX-202 in Healthy Subjects and Patients With Psoriasis.

Healthy Volunteers | Mild to Moderate Psoriasis

United Kingdom
Nanjing Ruijie Pharma Co., Ltd.

Recruiting

Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects

Drug Safety

China
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single Ascending Doses Phase I Study to Evaluate the Safety and Pharmacokinetics of RBD4059 in Healthy Subjects

Healthy Volunteers

Australia
AstraZeneca
Parexel

Recruiting

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Healthy Subjects | Crohns Disease

United Kingdom
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Single- and Multiple- Ascending Dose and Food Effect Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-7535 in Healthy Subjects

Healthy Subjects
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

Single Ascending Dose and Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-1816 in Healthy Subjects

Diabetes
Jiangsu Nhwa Pharmaceutical Co., Ltd.

Recruiting

Single Ascending Dose Study of NH102 in Healthy Subjects

Depression

China
Jiangsu Nhwa Pharmaceutical Co., Ltd.

Recruiting

A Single Ascending Dose Study Of CY150112 After Single Oral Administration in Healthy Chinese Subjects

Schizophrenia

China
Cidara Therapeutics Inc.

Completed

A Single Ascending Dose Study of CD101 IV in Healthy Subjects

Healthy

United States
Amgen

Completed

Single Ascending Dose Study of AMG 570 in Healthy Subjects

Systemic Lupus Erythematosus

United States
Ono Pharmaceutical Co. Ltd

Completed

Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and PK of ONO-2910 in Japanese and Caucasian Subjects

Healthy Volunteers

Japan
Ono Pharmaceutical Co. Ltd

Completed

Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD of ONO-4685 in Japanese and Caucasian Healthy Adult Male Subjects

Healthy Volunteers

Japan
Walden Biosciences

Completed

Single Ascending Dose Study of WAL0921 in Healthy Subjects

Healthy

United States
Ornovi, Inc.

Withdrawn

A First in Human Single and Multiple Ascending Dose and Open Label Food Effect Study of OR-101 in Healthy Subjects

Alopecia Areata

Australia
Beckley Psytech Limited

Completed

Single Ascending Dose Study With BPL-003 in Healthy Subjects

Pharmacokinetics in Healthy Adults

United Kingdom
Guangzhou Zhiyi Biotechnology Co., Ltd.

Completed

A Sequential Single and Multiple Ascending Dose (SAD/MAD) Study of SK10 Powders in Healthy Adult Subjects

Chemotherapy-induced Diarrhea

United States
Celsius Therapeutics, Inc.

Completed

First-in-human, Single Ascending Dose Study of CEL383 in Healthy Adult Subjects

Healthy

United States
Aelis Farma
European Commission

Completed

AEF0217 First-in-Human Phase I Study in 3 Parts (Single and Multiple Ascending Doses, and Food Effect) in Healthy Subjects. (AEF0217-101)

Safety, Tolerability, Pharmacokinetics of AEF0217

Spain
Haisco Pharmaceutical Group Co., Ltd.

Completed

Ascending Single-Dose and Multiple-Dose Study to Evaluate HSK31679 in Healthy Subjects and Subjects With Elevated LDL-C

Healthy | Elevated LDL-C

China
AstraZeneca

Completed

Assess the Safety, Tolerability, and Pharmacokinetics of AZD6234 Following Single Ascending Dose Administration to Healthy Subjects Who Are Overweight or Obese

Healthy Participants

United States
GlaxoSmithKline
Affinivax, Inc.

Completed

A Single Ascending Dose Study in Adults (Stage 1) and Single Ascending Dose-Finding Study (Stage 2) in Elderly Subjects With ASP3772, A Pneumococcal Vaccine

Pneumonia, Bacterial | Healthy Volunteers | Pneumococcal Disease

United States
Graviton Bioscience Corporation

Completed

Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects

Phase 1

United States
Enanta Pharmaceuticals, Inc

Completed

A Study of EDP-323 in Healthy Subjects

RSV Infection

United States
AstraZeneca

Completed

A Study to Investigate the Safety, Tolerability and Effects of AZD8630 in Healthy Subjects and Subjects With Asthma on Inhaled Corticosteroids and Long-acting Beta-agonists

Asthma

United States, Germany, United Kingdom
Madrigal Pharmaceuticals, Inc.

Completed

Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects

Drug Safety

United States
AstraZeneca
Parexel

Completed

A First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry.

Healthy Volunteers

United States
Société des Produits Nestlé (SPN)

Completed

Oral CDX-7108 in Healthy Adults and EPI Subjects

Exocrine Pancreatic Insufficiency

Australia, New Zealand
Samus Therapeutics, Inc.

Terminated

A Single and Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of PU-AD in Healthy Subjects

Alzheimer's Disease

United States
Daiichi Sankyo, Inc.

Completed

A Study of a Single Ascending Dose Study of DS-7011a in Healthy Subjects

Systemic Lupus Erythematosus

United States
MyMD Pharmaceuticals, Inc.

Completed

Single Ascending and Multiple Dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male and Female Adult Subjects

Hashimoto Disease

United States
Gan and Lee Pharmaceuticals, USA

Completed

Single, Ascending Dose, First Time in Human Study for GZR18 in Healthy Subjects

Diabetes Mellitus, Type 2

United States
Daiichi Sankyo, Inc.

Completed

A Study to Assess the Safety and Pharmacokinetics of Single Ascending Subcutaneous and Intravenous Doses of DS-2325a in Healthy Subjects

Netherton Syndrome

United States
Viriom

Completed

Study of Single Ascending Doses of Elsulfavirine to Evaluate the Safety, Tolerability, and Pharmacokinetics of Elsulfavirine and Its Active Metabolite VM-1500A in Healthy Subjects

HIV-1-infection

United States
Drugs for Neglected Diseases
Wellcome Trust grant 212346/Z/18/Z - 21st Century Treatments for Sustainable...

Completed

Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects

Visceral Leishmaniasis | Cutaneous Leishmaniases

United Kingdom
Beckley Psytech Limited

Completed

Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects

Pharmacokinetics in Healthy Adults

United Kingdom
Z Factor Limited
Hammersmith Medicines Research; Centessa Pharmaceuticals plc

Terminated

A Single Ascending and Repeated Dose Study of Oral ZF874 in Healthy Volunteers and PiXZ Subjects

Alpha1 Anti-Trypsin Deficiency

United Kingdom
EnnovaBio Australia Pharmaceuticals Pty Ltd

Completed

A First-in-human Single Ascending Dose/Multiple Ascending Dose Study of ENN0403 in Healthy Subjects

Healthy

Australia
Enanta Pharmaceuticals, Inc

Completed

A Study of EDP-235 in Healthy Subjects

SARS CoV 2 Infection

United States
Daiichi Sankyo Co., Ltd.

Completed

Study of Single-Ascending Doses of DS-6016a in Healthy Japanese Subjects

Fibrodysplasia Ossificans Progressiva

Japan
AbbVie
KU Leuven; Syndesi Therapeutics

Completed

A Single Ascending Oral Dose Study of SDI-118 in Healthy Male Subjects Including an Assessment of Receptor Occupancy and Food Effect

Cognitive Disorders

Belgium
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

Healthy

Netherlands
Vigonvita Life Sciences

Completed

Safety and Pharmacokinetics Study of Single Ascending Doses of VV116 in Healthy Volunteers

Healthy Subjects

China
Affinivax, Inc.

Completed

Single Ascending Dose of ASP3772 Study in Japanese Healthy Male and Female Adults, and Single Ascending Dose Study of ASP3772 in Comparison With PPSV23 in Japanese Elderly Male and Female Subjects

Healthy Volunteers

Japan
Sanofi

Completed

Single Ascending Dose Study of SAR443820 in Healthy Adult Chinese and Japanese Female and Male Participants

Multiple Sclerosis Healthy Subjects

United Kingdom
AstraZeneca
Parexel

Completed

A Study to Evaluate the Safety and Pharmacokinetics With MEDI8367 Administered in Healthy Subjects, and in Subjects With Chronic Kidney Disease

Chronic Kidney Disease

United States

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