Search clinical trials for: Sitagliptin (Januvia)

Total 535 results

Astellas Pharma Inc

Completed

A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Sitagliptin When Given Together to Healthy Subjects

Healthy | Pharmacokinetics of ASP1941

United States
Blandine Laferrere
Merck Sharp & Dohme LLC

Completed

Treatment of Diabetes After Gastric Bypass With Sitagliptin (LAF33)

Type 2 Diabetes Mellitus

United States
University of Alabama at Birmingham

Terminated

Changes in Bone Turnover With Increased Incretin Hormone Exposure (DRTC)

Type 2 Diabetes Mellitus

United States
Georgetown University
Merck Sharp & Dohme LLC

Terminated

Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers

Type II Diabetes

United States
University of Oslo School of Pharmacy
Oslo University Hospital

Completed

Sitagliptin in Renal Transplant Recipients

Glucose Intolerance

Norway
University at Buffalo
Merck Sharp & Dohme LLC

Completed

The Effect of Januvia (Sitagliptin) on Oxidative Stress in Obese Type 2 Diabetic Subjects (1928)

Type 2 Diabetes

United States
Merck Sharp & Dohme LLC

Completed

Januvia Re-examination Study (MK-0431-181)

Type 2 Diabetes Mellitus
Johns Hopkins University
Merck Sharp & Dohme LLC

Terminated

Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)

Glucose Homeostasis

United States
AstraZeneca
Eli Lilly and Company

Completed

A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin

Type 2 Diabetes Mellitus

Korea, Republic of, Mexico, Germany, Greece, Argentina, India, Australia
Sheba Medical Center

Completed

Effect of Januvia on Beta Cell Function in Patients With Diabetes Mellitus

Diabetes Mellitus Type 2

Israel
Merck Sharp & Dohme LLC

Completed

A Post Marketing Safety Study of Sitagliptin (JANUVIA®) (MK-0431-234)

Diabetes Mellitus, Type 2
Janssen Research & Development, LLC

Completed

The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)

Diabetes Mellitus, Type 2

United States, Canada, France, Poland, Germany, Israel, India, Ukraine, Korea, Republic of, Malaysia, Netherlands, New Zealand, Singapore, Brazil, Austria, Denmark, Belgium
Emory University
Merck Sharp & Dohme LLC

Terminated

DPP-4 Inhibition and TZD for DM Prevention (DInT DM)

Prediabetic State

United States
University of Colorado, Denver

Completed

Assessing Glucose Effects of Sitagliptin (Januvia) in Adult Patients With Type 1 Diabetes

Type 1 Diabetes

United States
Janssen Research & Development, LLC

Completed

The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone)

Diabetes Mellitus, Type 2

United States, Germany, Spain, Mexico, India, Canada, Greece, Thailand, United Kingdom, Finland, France
Merck Sharp & Dohme LLC

Completed

Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)

Diabetes Mellitus, Non-Insulin-Dependent
HealthPartners Institute
Amylin Pharmaceuticals, LLC.

Completed

Use of Continuous Glucose Monitoring Combined With Ambulatory Glucose Profiles to Characterize Glycemic Control

Type 2 Diabetes

United States
AstraZeneca
Eli Lilly and Company

Completed

Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)

Type 2 Diabetes Mellitus

United States, Brazil, Italy, Korea, Republic of, Mexico, Poland, Russian Federation, Spain, Turkey, United Kingdom, South Africa, Argentina, Canada, Germany, Hungary, Israel, Romania, Slovakia, India, Belgium, France, Puerto Rico
Albert Einstein College of Medicine
Medtronic

Completed

Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop

Diabetes Mellitus, Type 1

United States
Wayne State University

Unknown

Effect of Januvia on Ghrelin and Other Gut Hormones in Patients With Diabetes

Type 2 Diabetes

United States
AstraZeneca
Eli Lilly and Company

Completed

A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)

Type 2 Diabetes Mellitus

United States, Mexico, India
National Institute of Diabetes and Digestive and...

Completed

Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

Diabetes Mellitus Type 2 | Diabetes Mellitus Type 1

United States
Chong Kun Dang Pharmaceutical

Completed

CKD-396 Drug-drug Interaction Study(B) (CKD-396 DDI(B) P1)

Diabetes Mellitus Type 2

Korea, Republic of
Janssen Research & Development, LLC

Completed

The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial)

Diabetes Mellitus, Type 2

United States, Poland, Colombia, Mexico, Portugal, Bulgaria, India, Malaysia, Turkey, Ukraine, Greece, Sweden, Singapore, Czech Republic, Argentina, Puerto Rico, Russian Federation, Thailand, Slovakia, Latvia, Estonia, Peru
University College Dublin

Completed

Dipeptidyl Peptidase-4 Inhibition and Narrow-band Ultraviolet-B Light in Psoriasis (DINUP) (DINUP)

Psoriasis

Ireland
Lexicon Pharmaceuticals

Completed

A Study to Evaluate the Pharmacodynamic Effects of Single-Dose Co-Administration of LX4211 With Januvia® in Type 2 Diabetics

Type 2 Diabetes Mellitus

United States
The University of Texas Health Science Center at...

Completed

Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM

Diabetes

United States
Merck Sharp & Dohme LLC

Completed

An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)

Type 2 Diabetes Mellitus
Handok Inc.

Unknown

Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)

Type 2 Diabetes Mellitus

Korea, Republic of
Charite University, Berlin, Germany
Center for Molecular Medicine

Unknown

Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy (Nikolo)

Colorectal Cancer

Germany
University of Colorado, Denver

Completed

Incretin Effect in People With Impaired Fasting Glucose (1651)

Obesity

United States
University of Vermont
Merck Sharp & Dohme LLC

Unknown

Bone Turnover in Type 2 Diabetes Patients

Type 2 Diabetes

United States
Merck Sharp & Dohme LLC

Completed

Double-blind Sitagliptin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Ipragliflozin (MK-0431J-842)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262)

Type 2 Diabetes Mellitus
University of British Columbia

Terminated

Sitagliptin in Cystic Fibrosis-Related Diabetes

Cystic Fibrosis

Canada
University of Baghdad

Recruiting

Effectiveness of Niclosamide as Add-on Therapy to the Standard of Care Measures in COVID-19 Management

Covid-19 | SARS Pneumonia

Iraq
Meir Medical Center
Clalit Health Services

Unknown

A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin

Diabetes Type 2

Israel
Merck Sharp & Dohme LLC

Completed

Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)

Type 2 Diabetes Mellitus
Beni-Suef University

Not yet recruiting

Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients

Polycystic Ovary Syndrome

Egypt
Takeda

Completed

Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Mexico
Merck Sharp & Dohme LLC

Completed

An Open-Label, Single- & Multiple-Dose Study to Investigate the Pharmacokinetics of Sitagliptin 100 mg in Healthy Chinese Adult Subjects (0431-108)(COMPLETED)

Diabetes Mellitus Non-insulin-dependent
University of Sao Paulo General Hospital
University of Sao Paulo

Completed

"Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients"

Diabetes Type 2

Brazil
Charles Drew University of Medicine and Science
National Center for Research Resources (NCRR)

Completed

Sitagliptin in Combination With Metformin and Sulfonylurea

Type 2 Diabetes Mellitus

United States
Merck Sharp & Dohme LLC

Completed

A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Insulin With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-254)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC
Duke Clinical Research Institute, Oxford Diabetes Trials Unit

Completed

Sitagliptin Cardiovascular Outcomes Study (MK-0431-082) (TECOS)

Type 2 Diabetes Mellitus
Novartis Pharmaceuticals

Completed

Vildagliptin vs Sitagliptin add-on to Insulin - Impact on Glycemic Profile and Correlation of Hypoglycemic Episodes and Heart Function (CGM-VISIT)

Diabetes Mellitus Type 2

Germany
Merck Sharp & Dohme LLC

Completed

Sitagliptin Added-on to Insulin Study (0431-051)

Type 2 Diabetes Mellitus
Seoul National University Bundang Hospital

Completed

Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients

Type 2 Diabetes

Korea, Republic of
Merck Sharp & Dohme LLC
Pfizer

Completed

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Diabetes Mellitus, Type 2

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