Search clinical trials for: TNF inhibitor

Total 68373 results

Diakonhjemmet Hospital
Karolinska University Hospital; Medical University of Vienna; Oslo University... and other collaborators

Not yet recruiting

Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease Control in Adults With Rheumatoid Arthritis on a Subcutaneous TNF Inhibitor: The Rheumatoid Arthritis Therapeutic DRUg Monitoring Trial (RA-DRUM) (RA-DRUM)

Rheumatoid Arthritis

Austria, Sweden, Norway, United Kingdom
Sun Yat-sen University

Recruiting

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

Malignant Ascites

China
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Prof Curdin Conrad
Centre Hospitalier Universitaire Vaudois

Not yet recruiting

TYK2 Inhibition in Paradoxical Psoriasis (TYPP)

Psoriasis

Switzerland
Vastra Gotaland Region

Recruiting

Comparison Between Infliximab and Adalimumab on Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Sweden
NorthShore University HealthSystem
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effects of TNF Blockade on Human BPH/LUTS

Benign Prostatic Hyperplasia (BPH)

United States
Tom Appleton
Western University; Canadian Research Group in Immuno-Oncology

Not yet recruiting

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis | Immune-related Adverse Event
Hospital del Río Hortega
Francisco Javier Garcia Alonso; Jesús Barrio

Recruiting

Influence of HLA-DQA1*05 Genotype in Adults With Anti-TNF Treatment With Proactive Therapeutic Drug Monitoring. (Proa-DQ)

Inflammatory Bowel Diseases | Drug Monitoring

Spain
Federico II University
Crohn's and Colitis Foundation

Not yet recruiting

AppenDectomy Vs ANti TNF-a in Inducing Clinical and EnDoscopic Remission in Left-sided Ulcerative Colitis (ADVANCED-UC)

Ulcerative Colitis
Assistance Publique - Hôpitaux de Paris

Recruiting

Certolizumab in Recurrent Implantation Failure (RIF) (CERTIFY)

Recurrent Unexplained Implantation Failure

France
University of Calgary
Alimentiv Inc.

Recruiting

PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's Disease

Crohn Disease

Canada
Lihua Duan

Not yet recruiting

Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ Fusion Protein in the Treatment of Acute Gout

Acute Gout

China
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Austria, Italy, Bulgaria, Israel, Taiwan, Croatia, Hungary, Netherlands, Switzerland, Germany, Portugal, France, United Kingdom, Czechia, ... and more
Institut Claudius Regaud
Institut National de la Santé Et de la Recherche Médicale, France

Recruiting

Blocking TNF to Potentiate the ICI-dependent Immune Awakening in Melanoma (ATPIC)

Melanoma | Immune Defect | Tumor Skin

France
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis (SELECT- SWITCH)

Rheumatoid Arthritis

United States, Japan, United Kingdom, Canada, Korea, Republic of, Puerto Rico, South Africa, Hungary, Bulgaria, Spain, Portugal, Chile, Croatia, France, Belgium, Germany, Greece, Romania, Brazil, Italy, Serbia, China, Colombia, Mexico
Connecticut Children's Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emory... and other collaborators

Recruiting

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease (CAMEO)

Crohn Disease

United States, Canada
Insel Gruppe AG, University Hospital Bern
Bristol-Myers Squibb

Recruiting

Combined Microbiota and Metabolic Signature in Ulcerative Colitis Predicts Anti-Inflammatory Therapy Success (COMMIT)

Ulcerative Colitis

Switzerland
University of Pennsylvania
Janssen Scientific Affairs, LLC

Recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
University of Pennsylvania
Janssen Scientific Affairs, LLC

Not yet recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
Qilu Hospital of Shandong University

Recruiting

The Clinical Efficacy of Immunomodulators in RA Patients

Arthritis, Rheumatoid

China
ANRS, Emerging Infectious Diseases

Recruiting

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis (TIMPANI)

Tuberculous Meningitis | HIV I Infection

Mozambique, Brazil, Zambia
Sohag University

Not yet recruiting

Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheumatoid Arthritis

Rheumatoid Arthritis
University Hospital, Montpellier

Recruiting

Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis (SEQUENS-RA)

Rheumatoid Arthritis

France, Monaco
Fundación de Investigación Biomédica - Hospital...

Recruiting

Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events

Ulcerative Colitis | Thromboembolism

Spain
Marie Hudson, MD
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Recruiting

Stand UP to Rheumatoid Arthritis (SUPRA) (SUPRA)

Rheumatoid Arthritis

Canada
TILT Biotherapeutics Ltd.
Merck Sharp & Dohme LLC

Recruiting

Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab and Pegylated Liposomal Doxorubicin as Treatment for Ovarian Cancer. (PROTA)

Platinum-resistant Ovarian Cancer | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Refractory Fallopian Tube Carcinoma | Platinum-Refractory Primary Peritoneal Carcinoma | Platinum-refractory Ovarian Carcinoma | Platinum-Sensitive Ovarian... and other conditions

United States, Finland
TILT Biotherapeutics Ltd.

Recruiting

Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1 (AVENTIL)

Melanoma | Head and Neck Squamous Cell Carcinoma

United States, Finland
Hanyang University Seoul Hospital
Linical Korea

Not yet recruiting

REduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST)

Ankylosing Spondylitis | Axial Spondyloarthritis
Dan Liang

Recruiting

Reduction or Discontinuation of TNF-α Inhibitor in Non-infectious Uveitis Patients

Uveitis | Adalimumab

China
Ottawa Hospital Research Institute
The Ottawa Hospital; University of Ottawa

Not yet recruiting

Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patients Receiving JAK-inhibitor vs. TNF-inhibitor Therapy for Active Rheumatoid Arthritis: A Feasibility Study.

Rheumatoid Arthritis
Jeffrey Curtis
Bristol-Myers Squibb; Eli Lilly and Company; University of Pennsylvania; Novartis; Pfiz... and other collaborators

Recruiting

COVID-19 VaccinE Response in Rheumatology Patients (COVER)

Rheumatoid Arthritis | Spondylarthritis | Psoriatic Arthritis

United States
University Hospital, Bordeaux
Eli Lilly and Company; Biogen; Ministry for Health and Solidarity, France

Recruiting

Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis (CRI-RA)

Rheumatoid Arthritis

France, Monaco
Centre Hospitalier Universitaire de Besancon

Recruiting

Evaluation of Mood Disorders Under Biologics in Chronic Inflammatory Rheumatic Disease (EMOTION)

Mood Disorders | Rheumatic Diseases

France
Aalborg University Hospital

Recruiting

Characterization of Immunogenicity of TNF Inhibitors in Arthritis Patients With Poorer Treatment Response.

Arthritis, Rheumatoid | Arthritis, Psoriatic | Spondylitis, Ankylosing

Denmark
Sun Yat-sen University

Recruiting

A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection

Hepatocellular Carcinoma Recurrent

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma (HCC)

China
Eli Lilly and Company
Incyte Corporation

Recruiting

A Study of Baricitinib in Participants With Rheumatoid Arthritis (RA-BRANCH)

Rheumatoid Arthritis

United States
Fundación de Investigación Biomédica - Hospital...

Recruiting

Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease (BioIBD)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

Spain
Shinshu University

Recruiting

Usefulness of Non TNF Usage in RA Patients

Rheumatoid Arthritis

Japan
Rennes University Hospital

Recruiting

EFFICACI : EFFicacy of Intravenous Infliximab Versus Vedolizumab After Failure of subCutaneous Anti-TNF in Patients With UlCerative Colitis (EFFICACI)

Ulcerative Colitis

France
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Recruiting

Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis (ROC-SPA)

Axial Spondyloarthritis

France, Monaco
Lille Catholic University

Recruiting

Abatacept vs Tocilizumab for the Treatment of RA in TNF Alpha Inhibitor Inadequate Responders (SUNSTAR)

Arthritis, Rheumatoid

France
Assistance Publique - Hôpitaux de Paris
Societe Francaise de Rhumatologie

Recruiting

French National Registry: ART REGISTRY (Observational Study) (ART)

RheumatoId Arthritis

France
Helse Møre og Romsdal HF
University of Oslo; Oslo University Hospital

Active, not recruiting

Anti-tumor Necrosis Factor in Patients With Ulcerative Colitis in Clinical Remission: to Continue or Not? (BIOSTOP)

Colitis,Ulcerative

Norway
Eli Lilly and Company
Incyte Corporation

Active, not recruiting

A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA-BRIDGE)

Rheumatoid Arthritis

Spain, United States, Hungary, Australia, Turkey, Czechia, Belgium, United Kingdom, Poland, Puerto Rico, Israel, Switzerland, France, South Africa, Romania, Italy, Germany, Netherlands, Austria, Denmark, Lithuania, Russian Federation and more
Novartis Pharmaceuticals

Active, not recruiting

Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNFα-Inhibitor Treatment (AgAIN)

Psoriatic Arthritis

Germany
Acerta Pharma BV

Active, not recruiting

A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL

Chronic Lymphocytic Leukemia

Austria, Italy, Spain, United Kingdom, Belgium, Taiwan, France, Korea, Republic of, Hungary, United States, Ukraine, Canada, Australia, Germany, Israel, Czechia, Russian Federation, Slovakia, Poland, Bulgaria, New Zealand, Sweden, C... and more
Janssen Research & Development, LLC

Active, not recruiting

A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy (GO-VIVA)

Arthritis, Juvenile

United States, Israel, Mexico, South Africa, Canada, Brazil, Argentina, Russian Federation, Chile
Janssen Biotech, Inc.

Active, not recruiting

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease (DEVELOP)

Inflammatory Bowel Diseases | Crohn's Disease | Ulcerative Colitis | Indeterminate Colitis

United States, Canada
Alimentiv Inc.

Active, not recruiting

Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis (PROTOS)

Ulcerative Colitis

United States, Canada

Search clinical trials for: TNF inhibitor

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