Search clinical trials for: Therapeutic Exposure

Total 16151 results

BioAegis Therapeutics Inc.

Not yet recruiting

Rhu-pGSN to Mitigate Proinflammatory Responses to Decompression in Healthy SCUBA Divers

Decompression Sickness
Eva Heim

Recruiting

Complex-Posttraumatic Stress Disorder - Cultural Adaptation of a Therapeutic Manual and Development of a Culture-specific Diagnostic Module for Refugee Populations in Switzerland (Pilot Trial)

Complex Post-Traumatic Stress Disorder

Switzerland
LUNGevity Foundation
Bristol-Myers Squibb; Eli Lilly and Company; Merck Sharp & Dohme LLC; Novartis; T... and other collaborators

Recruiting

Project PEER: Understanding the Lung Cancer Patient ExperiEnce in the Real-World Setting (PEER)

Caregivers | Lung Cancer Patients

United States
Catharina Ziekenhuis Eindhoven

Recruiting

Therapeutic Oncolytic Monitoring as a Tool for Effective Exposure to 5-FU in Patients With Locally Advanced, Resectable Gastric or Gastro-oesophageal Junction Cancer Treated With Perioperative FLOT (THOMAS FU FLOT)

TDM of 5-FU | Pharmacokinetic Observational Study

Netherlands
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pre-therapeutic Validation of the Virtual Reality-based Exposure Scenario for CBT "ReVBED" for the Induction of Food Craving in Patients With Bulimia and Binge Eating Disorder (BED) (RevBED)

Binge-Eating Disorder | Bulimia Nervosa

France
Thomas Adams

Recruiting

Exercise and Therapeutic Exposure

PTSD

United States
Universidad Autonoma de Baja California
Universidad Internacional de Valencia; Universidad Nacional Autonoma de Mexico and other collaborators

Not yet recruiting

Online Psychological Treatment for Rat Phobia Guided by a Virtual Assistant

Specific Phobia | Anxiety Disorder
University of Seville

Recruiting

Pain Neuroscience Education and Graded Exposure to Movement in Breast Cancer Survivors

Quality of Life | Breast Neoplasms | Pain, Chronic

Spain
Texas Woman's University

Recruiting

The Effect of an Individualized Impairment-based, Orthopedic Physical Therapy Intervention (IOI), on Muscle Stiffness, Pelvic Floor Function, and Pain in Women With Chronic Pelvic Pain

Chronic Pain | Pelvic Pain | Muscle Tightness

United States
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
Rennes University Hospital

Recruiting

Observational Study Comparing the Efficacy of Ganciclovir as a Function of Blood Exposure to the Drug During a Curative or Preemptive Treatment (GANEX)

Solid Organ Transplantation

France
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Puerto Rico
Mayo Clinic
National Cancer Institute (NCI)

Completed

Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery

Gastroesophageal Junction Adenocarcinoma | Gastric Cardia Adenocarcinoma | Stage IB Gastric Cancer AJCC v7 | Stage II Gastric Cancer AJCC v7 | Stage IIA Gastric Cancer AJCC v7 | Stage IIB Gastric Cancer AJCC v7 | Stage IIIA Gastric Cancer AJCC v7 | Stage IIIB Gastric Cancer AJCC v7

United States
Universidad Complutense de Madrid
Hospital Infantil Universitario Niño Jesús, Madrid, Spain

Active, not recruiting

Effectiveness of Whole-Body Vibration (WBVibration)

Muscle Spasticity | Spastic Cerebral Palsy | Vibration; Exposure | Physical Therapy Modalities | Lower Extremity Weakness, Spastic

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Neoadjuvant and Adjuvant Checkpoint Blockade

Stage IV Cutaneous Melanoma AJCC v6 and v7 | Ocular Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Cutaneous Melanoma | Mucosal Melanoma | Stage IIIB Cutaneous Melanoma AJCC v7 | Stage IV Uveal Melanoma AJCC v7 | Stage IIIB Uveal Melanoma AJCC v7 | Stage IIIC Uveal Melanoma AJCC v7 | Stage III Acral... and other conditions

United States
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection

H.Pylori Infection

China
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; ViiV Healthcare

Active, not recruiting

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

HIV Infections

Brazil, United States, South Africa, Peru, Thailand, Argentina, Vietnam
Jianersheng (Zhuhai) Pharmaceutical Technology...

Completed

Safety Study of GMDTC Injection in Healthy Participants

Cadmium Exposure

China
Canadian Cancer Trials Group
Canadian Cancer Society (CCS); ATGen Canada Inc; Ontario Institute for Cancer... and other collaborators

Active, not recruiting

Immunization With IMM-101 vs Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure (COV-IMMUNO)

Covid-19 | Cancer

Canada
Abbisko Therapeutics Co, Ltd

Enrolling by invitation

A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021

Healthy Subjects

China
Howard University
National Institute of Mental Health (NIMH); Georgetown-Howard Universities...

Completed

Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

United States
Marinomed Biotech AG

Completed

Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis

Allergic Rhinitis | Allergic Conjunctivitis

Austria
Leidos Life Sciences
United States Department of Defense

Terminated

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (Addendum 2)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection

United States
Assistance Publique - Hôpitaux de Paris

Completed

Therapeutic Effects of Horticulture on Anterior Cingulate Cortex Activation in People With Chronic Low Back Pain (HORTICARE)

Low Back Pain

France
ProQR Therapeutics

Active, not recruiting

A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE) (ILLUMINATE)

Eye Diseases | Neurologic Manifestations | Eye Diseases, Hereditary | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

United States, Belgium, Brazil, Canada, France, Germany, Italy, Netherlands, United Kingdom
Sungkyunkwan University
National Research Foundation of Korea

Completed

Maternal and Neonatal Outcomes Following Exposure to Benzodiazepines During Pregnancy

Pregnancy Related | Congenital Anomaly | Benzodiazepines Causing Adverse Effects in Therapeutic Use

Korea, Republic of
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group; HIV Prevention Trials Network

Completed

Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk Women

HIV Infection

United States, Puerto Rico
Phoenicis Therapeutics

Terminated

A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 Gene

Epidermolysis Bullosa Dystrophica, Recessive | Epidermolysis Bullosa Dystrophica, Dominant

United States, Spain, France
Melinta Therapeutics, Inc.

Completed

Relative Exposure and Safety Study of Kimyrsa in ABSSSI Patients

Acute Bacterial Skin and Skin Structure Infection

United States
VA Office of Research and Development

Completed

Treatment of Prolonged Grief Disorder in Combat Veterans (PGD)

Prolonged Grief Disorder

United States
TherapeuticsMD

Completed

Annovera™ Drug-Drug Interaction Study

Contraception | Women

Canada
Cidara Therapeutics Inc.

Completed

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension (STRIVE)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis

United States, Spain, Belgium, Russian Federation, Greece, Bulgaria, Canada, Hungary, Italy, Romania
Allergy Therapeutics

Terminated

Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
Marinomed Biotech AG

Completed

Demonstration of Equivalence and Early Onset of a Novel Anti-allergic Nasal Spray Compared to Marketed Nasal Spray

Allergic Rhinitis | Allergic Conjunctivitis | Hayfever

Austria
Aldeyra Therapeutics, Inc.

Completed

A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber

Conjunctivitis, Allergic

Canada
Corcept Therapeutics

Completed

Study in Healthy Subjects to Determine the Effect of an Inhibitor on Exposure to Relacorilant and Its Metabolites

Healthy

United States
Assistance Publique Hopitaux De Marseille

Unknown

Cetuximab Therapeutic Drug Monitoring in Squamous Cell Carcinoma Head and Neck Cancer Patients: Determination of the Predictive Value Exposure Levels Through a Single Arm Multicentric Study (CETUXIMAX)

Head and Neck Cancer

France
Pfizer

Completed

A Phase 1 Study To Evaluate The Effect Of Glasdegib On The Cardiac Repolarization In Healthy Subjects (B1371023)

Healthy Volunteers

Belgium
Bradley Hospital

Unknown

Examining Behavioral Strategies for Enhancing Therapists' Delivery of Exposure Therapy (STRIVE)

Anxiety Disorders

United States
Faes Farma, S.A.
Allied Research International

Completed

PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)

Seasonal Allergic Rhinitis | Hay Fever | Rhinoconjunctivitis

Canada
Amsterdam UMC, location VUmc

Completed

Sorafenib Administered Using a High-dose, Pulsatile Regimen: a Phase I Exposure Escalation Study (SOPRANO)

Neoplasms

Netherlands
Nerre Therapeutics Ltd.

Completed

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Pharmacokinetic Study in Healthy Male Volunteers

United Kingdom
Corcept Therapeutics

Completed

Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s

Healthy

United States
National Cancer Institute (NCI)

Terminated

Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma

Anaplastic Large Cell Lymphoma | Recurrent Childhood Anaplastic Large Cell Lymphoma

United States
Corcept Therapeutics

Completed

Crossover Drug-Drug Interaction Study to Determine Effects of Cytochrome P450 3A on Exposure to Mifepristone and Its Metabolites

Healthy

United States
Federal University of Bahia

Completed

Virtual Rehabilitation and Conventional Therapeutic Exercises in the Treatment of Individuals Post Stroke

Stroke | Cerebrovascular Disorders

Brazil
Assistance Publique - Hôpitaux de Paris
ANSES, France; INERIS, Verneuil-En-Halatte, France

Completed

Evaluation of a Specialized Therapeutic Care of Patients Presenting an Intolerance Attributed to Electromagnetic Fields (IEI-CEM)

Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields

France
Philipps University Marburg Medical Center

Completed

Therapeutic Strategies During Exposure to Pain in an Experimental Design

Pain, Acute

Germany
Philipps University Marburg Medical Center
Psychotherapie-Ambulanz Marburg e.V.

Completed

Single-Case Study on Therapeutic Change in Chronic Low Back Pain

Chronic Low Back Pain

Germany
DUSA Pharmaceuticals, Inc.

Completed

Maximal Use Systemic Exposure (MUSE) Study of Levulan Kerastick

Keratosis, Actinic

United States

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