Search clinical trials for: Tissue concentration

Total 63059 results

First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients With Advanced GISTs

Gastrointestinal Stromal Tumors
University Hospital Center of Martinique
Institut Pasteur de Guadeloupe; Centre de Ressources Biologiques de la Martinique...

Not yet recruiting

Systemic Lupus Erythematosus and Chlordecone Impregnation in Martinique (LUNEK)

Systemic Lupus Erythematosus | Renal Disease

France
Tanta University

Not yet recruiting

The Remineralization of Early Enamel Caries in Permanent Teeth

White Spot Lesion

Egypt
Yeditepe University

Not yet recruiting

Attentional Focus Strategies in Exercise in Patients With Myofascial Pain Syndrome

Myofascial Pain Syndrome
Ungku Shahrin Medical Aesthetic Research & Innovation...

Recruiting

Safety of Serum for Post-Inflammatory on Hyperpigmentation Skin

Healthy

Malaysia
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
Emory University
National Cancer Institute (NCI); Verastem, Inc.

Recruiting

Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma

Glioblastoma | Recurrent Glioblastoma

United States
Indonesia University

Recruiting

Comparing Platelet-Rich Plasma (PRP) Centrifugation Methods on Thrombocyte Concentration and Clinical Improvement of Androgenetic Alopecia

Alopecia, Androgenetic

Indonesia
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

In Vitro Correction of Thrombin Generation by Concizumab (Anti-TFPI) for Severe Hemophilia Patients

Hemophilia

France
Boston Medical Center
American Society of Health-System Pharmacists

Recruiting

Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis (TDM-RA)

Rheumatoid Arthritis

United States
Second Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Predictive Value of Maternal Serum Pentraxin 3 (PTX 3) and Heparin-binding Protein (HBP) for Chorioamnionitis in Preterm Premature Rupture of Membranes

Preterm Premature Rupture of Membrane
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Description of the Copper Concentration in Breast Milk in Women Treated for Wilson's Disease (WILLACT)

Wilson's Disease

France
Wake Forest University Health Sciences

Recruiting

Oral Aromatase Inhibitors Modify the Gut Microbiome

Breast Cancer

United States
University of Colorado, Denver
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

HIV Outpatient Monitoring Evaluation Through Self-collection of Dried Blood Spots (HOME-1)

HIV Prevention | HIV Treatment

United States
Seoul National University Hospital

Recruiting

Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery

Diabetic Foot | Diabetic Neuropathies

Korea, Republic of
Bexion Pharmaceuticals, Inc.
CTI Clinical Trial and Consulting Services

Recruiting

A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (KONQUER)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
University Hospital, Clermont-Ferrand

Recruiting

Exploration of Differences in Metabolite Concentrations by 7Teslas NMR Spectroscopy in Striatum and Subthalamic Nuclei in de Novo Parkinsonian Patients and Control Subjects (METABO-NGC-7T)

Parkinson's Disease

France
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological Drug Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate and a First Biological Drug (POLYbio)

Rheumatoid Arthritis

France
CHU de Reims

Recruiting

Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma (PESTIPAC)

Carcinoma | Pancreatic Ductal

France
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Recruiting

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA)

Rheumatoid Arthritis

Netherlands
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy, Safety, and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO) (CIMcare)

Moderate Chronic Plaque Psoriasis | Severe Chronic Plaque Psoriasis | Mixed Guttate/Plaque Psoriasis

United States, Canada, Puerto Rico
University Hospital, Strasbourg, France
EUCLID Clinical Trial Platform; NS-PARK; F-CRIN

Recruiting

Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease. (PIMPARK)

Parkinson Disease

France
Université Catholique de Louvain

Recruiting

Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units (Pop-PK/PD)

Pharmacokinetics | Infection | Infection, Bacterial | Anti-Bacterial Agents | Drug Monitoring | Infections, Respiratory

Belgium
Regeneris Medical
Global Alliance for Regenerative Medicine

Recruiting

Biocellular-Cellular Regenerative Treatment Scaring Alopecia and Alopecia Areata (SAAA)

Alopecia Areata | Scarring Alopecia

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Relation Between Blood Concentration of Colchicine and Response to Colchicine Treatment in Gout Flare (COMpARE)

Gout Flare

France
Prasco LLC

Completed

Study to Evaluate the Equivalence of Estradiol Vaginal Cream to Reference Standard in the Treatment of Vaginal Atrophy

Vulvar and Vaginal Atrophy

United States
University of Toledo Health Science Campus

Completed

Platelet Rich Plasma in Knee Osteoarthritis

Knee Osteoarthritis

United States
West China Hospital

Completed

Efficacy and Safety of Different Concentrations of Sirolimus in the Treatment of Kaposiform Hemangioendothelioma.

Kaposiform Hemangioendothelioma

China
NeuroDerm Ltd.

Completed

A Safety, Tolerability, and Plasma Concentration Study of Levodopa/Carbidopa Subcutaneous Solution (ND0612) in Parkinson's Disease (PD) Patients

Parkinson's Disease

Israel
Disc Medicine, Inc

Active, not recruiting

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

Erythropoietic Protoporphyria

United States
Weill Medical College of Cornell University

Completed

Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis

Nail Diseases | Nail Psoriasis

United States
Sanofi

Completed

Study of the Tolerability of Different SAR153191 Drug Products, That Differ With Respect to Manufacturing Processes and Formulation, at Different Concentrations and Doses in Healthy Male Subjects

Rheumatoid Arthritis
Centre Hospitalier Universitaire de Saint Etienne

Completed

Normal Values of Parameters of Thrombin Generation in Function of Different Tissue Factor Concentrations (NUAGE)

Healthy Volunteers

France
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Completed

Adalimumab Dose Reduction Aiming Low Serum Concentration With Control of Disease Activity (ADDORA-low)

Rheumatoid Arthritis

Netherlands
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Active, not recruiting

Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment (ADDORA-switch)

Rheumatoid Arthritis

Netherlands
Timothy Ekhlassi

Enrolling by invitation

Comparison of Two Different Concentrations of Local Anesthetic in Patient Reported Pain in Oculoplastic Surgery

Pain | Dermatochalasis | Dermatochalasis of Eyelid | Dermatochalasis of Both Upper Eyelids | Dermatochalasis of Both Eyes | Dermatochalasis of Right Upper Eyelid | Dermatochalasis of Left Upper Eyelid

Canada
University of Texas Southwestern Medical Center

Terminated

Performance of Contrast-Enhanced Spectral Mammography to Assess Neoadjuvant Chemotherapy Response (CEDM)

Breast Cancer

United States
Istituto Ortopedico Galeazzi

Completed

Evaluation of IL-6 in Synovial Fluid in Obese and Normal Weight Patients Suffering From Gonarthrosis During PTA (IL6PG)

IL-6 Concentration in the Synovial Fluid of Obese Patients is 100% Higher Than the IL-6 Concentration of the Synovial Fluid in Normal Weight Patients

Italy
Roswell Park Cancer Institute
AIM ImmunoTech Inc.

Completed

Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer

Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple -Negative Breast Cancer | Anatomic Stage IV Breast Cancer AJCC

United States
Alexion

Completed

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Wilson Disease

United Kingdom, New Zealand, United States, Denmark, Russian Federation, Spain, Singapore
RWTH Aachen University

Completed

Concentration and Attentional Deficits in POTS and Other Autonomic Neuropathies (POTSKog)

Cognitive Impairment | Postural Tachycardia Syndrome | Dysautonomia | Pure Autonomic Failure | Ehlers-Danlos Syndrome | Autonomic Failure

Germany
Seoul National University Hospital
CHA University

Completed

Comparison of Concentration of Vasopressin During Robot-assisted Laparoscopic Myomectomy (VALENTINE)

Uterine Leiomyoma

Korea, Republic of
Bayer

Completed

Dose Escalation of Different Concentrations of ZK 245186 in Atopic Dermatitis

Atopic Dermatitis

South Africa
Mansoura University

Completed

Calprotectin and Ischemia Modified Albumin Serum to Measure Disease Activity in Behçet's Disease

Behçet's Diseasecases

Egypt
Botanix Pharmaceuticals

Completed

A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Hyperhidrosis

United States
Qlaris Bio, Inc.

Completed

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Ocular Hypertension | Glaucoma | Glaucoma Congenital | Sturge-Weber Syndrome (SWS)

United States
Hvidovre University Hospital

Terminated

Whole Blood Metal Ion Concentrations in Metal-on-metal Total Hip Arthroplasty and Hip Resurfacing

Osteoarthritis, Hip
Queen Savang Vadhana Memorial Hospital, Thailand

Completed

Intraarticular Leukocyte-rich and Leukocyte-poor PRP for Osteoarthritis of the Knee (PRP)

Osteo Arthritis Knee

Thailand
New York State Psychiatric Institute
University of Colorado, Denver; National Institute of Allergy and Infectious... and other collaborators

Completed

Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa (ADD-ART)

Therapeutic Adherence and Compliance

United States, South Africa
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium

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