Search clinical trials for: Trough concentration

Total 1730 results

Boston Medical Center
American Society of Health-System Pharmacists

Recruiting

Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis (TDM-RA)

Rheumatoid Arthritis

United States
Oncotelic Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of OT-101+Artemisinin in Hospitalized COVID-19 Subjects

COVID-19

Brazil
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Recruiting

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA)

Rheumatoid Arthritis

Netherlands
Rennes University Hospital

Recruiting

Observational Study Comparing the Efficacy of Ganciclovir as a Function of Blood Exposure to the Drug During a Curative or Preemptive Treatment (GANEX)

Solid Organ Transplantation

France
University Hospital, Basel, Switzerland

Completed

Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder

Febrile Neutropenia (FN)

Switzerland
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Active, not recruiting

Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment (ADDORA-switch)

Rheumatoid Arthritis

Netherlands
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium
Peking University Third Hospital

Completed

Vancomycin Dosage Strategy Based on a Trough Concentration Model

Pneumonia, Staphylococcal

China
University Hospital, Basel, Switzerland

Completed

Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate (ADA in PiRD)

Rheumatic Diseases

Switzerland, Germany
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
Kyungpook National University Hospital

Completed

Anti CT-P13 Antibody in Moderate to Severe Inflammatory Bowel Disease (OACIS)

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

Korea, Republic of
Sheba Medical Center

Completed

Effect of Vitamin D on Everolimus Trough Concentrations Among Heart Transplanted Patients

Vitamin D Deficiency

Israel
Pinyo Rattanaumpawan

Unknown

Vancomycin Dosage Adjustment for MRSA Infections

Methicillin-Resistant Staphylococcus Aureus

Thailand
People's Hospital of Zhengzhou University

Completed

Loading Regimen，Serum Trough Concentrations，Efficacy and Safety in Pneumonia Patients With Gram-positive Infections

Pneumonia Gram-Positive Bacterial
Oslo University Hospital

Completed

Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

Norway
Universitaire Ziekenhuizen KU Leuven

Unknown

Adalimumab Trough Concentrations in Crohn's Disease: A Pilot Pharmacokinetic Study

Crohn's Disease

Belgium
National Taiwan University Hospital

Completed

The Most Appropriate Parameter Correlates With Clinical Effectiveness of Vancomycin: Trough Drug Concentration or Area Under Curve (AUC)/Minimum Inhibitory Concentration (MIC)?

Methicillin-resistant Staphylococcus Aureus Septicemia

Taiwan
Bristol-Myers Squibb

Completed

Study to Assess Steady-State Trough Concentrations, Safety, and Immunogenicity of Abatacept After Subcutaneous (SC) Administration to Subjects With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
dingshifang
Shandong Provincial Hospital; Qianfoshan Hospital; Jinan Military General Hospital and other collaborators

Unknown

CYP 2C19 Polymorphism and Voriconazole Trough Concentration in Chinese Adult Patients

Invasive Pulmonary Aspergillosis

China
Hopital Lariboisière

Completed

Antiretroviral Therapy and Extreme Weight (EXTATIC)

HIV Infection

France
Chulalongkorn University

Completed

Concentration-controlled Therapy of Mycophenolate Mofetil (MMF) in Proliferative Lupus Nephritis

Lupus Nephritis

Thailand
Sheppard Pratt Health System
Stanley Medical Research Institute

Completed

Artemisinin to Reduce The Symptoms of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
The Canberra Hospital

Unknown

Dose Enhancement of Vancomycin IN Everyday Patients (DEVINE)

Vancomycin Therapy

Australia
Innovative Medical

Completed

Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects

Cataract

United States
Colgate Palmolive

Not yet recruiting

The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.

Gingivitis | Plaque
University of Sao Paulo

Not yet recruiting

Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization (LBIARHMI)

Molar Incisor Hypomineralization
University of Roma La Sapienza

Recruiting

Use of 'Mechanical Power' as a Predictor of Increased Serum and Pulmonary Proinflammatory Cytokine Concentrations in Patients With Acute Hypoxemic Respiratory Failure: A Prospective Observational Study

Mechanical Power

Italy
The First Affiliated Hospital of Xiamen University

Not yet recruiting

A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma

Gastric/Gastroesophageal Junction Adenocarcinoma
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

Attentional Focus in Virtual Reality

Attentional Focus in Virtual Reality
United States Naval Medical Center, San Diego
Minneapolis Veterans Affairs Medical Center; United States Department of Defense and other collaborators

Not yet recruiting

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Brain Injuries | Brain Injuries, Traumatic | Brain Concussion | Mild Cognitive Impairment | Memory Impairment | Mild Traumatic Brain Injury | Attention Impaired | Neurocognitive Dysfunction | Brain Trauma | Attention Concentration Difficulty | Post Concussive Symptoms

United States
Mayo Clinic
Universidade Federal de Goias; University of Wisconsin, Eau Claire

Recruiting

A Study of Melatonin Concentration During Lactation

Breastfeeding

United States
Phathom Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily

Helicobacter Pylori Infection | Heartburn | Erosive Esophagitis | Symptomatic Nonerosive Gasroesophageal Reflux Disease

United States
Mỹ Đức Hospital
Vrije Universiteit Brussel

Not yet recruiting

CAPA-IVM Culture With Low Oxygen Tension

In Vitro Fertilization

Vietnam
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
University Hospital Center of Martinique
Institut Pasteur de Guadeloupe; Centre de Ressources Biologiques de la Martinique...

Not yet recruiting

Systemic Lupus Erythematosus and Chlordecone Impregnation in Martinique (LUNEK)

Systemic Lupus Erythematosus | Renal Disease

France
University of Bergen
The Norwegian Seafood Research Fund

Not yet recruiting

Effect of Herring Oil Concentrate on LDL Cholesterol Concentration in Adults

High Cholesterol

Norway
Johns Hopkins University
ON Foundation

Not yet recruiting

Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes

Rotator Cuff Tears

United States
China Medical University, China

Recruiting

Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia

Oxygenation Index

China
Tanta University

Not yet recruiting

The Remineralization of Early Enamel Caries in Permanent Teeth

White Spot Lesion

Egypt
Aya Ayman Ahmed

Not yet recruiting

Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

Mandibular Fractures
AbbVie

Recruiting

A Study to Assess the Concentrations of Risankizumab in the Breast Milk of Adult Lactating Women With Inflammatory Bowel Disease

Inflammatory Bowel Disease

Israel
Ciusss de L'Est de l'Île de Montréal
CIUSSS du Nord de l'Ile de Montréal

Not yet recruiting

Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia (PRESCOD-AI)

Anesthesia
Essilor-Polylite Taiwan Co., Ltd.

Recruiting

Stellest Lenses and Low-concentration Atropine Myopia Control Among Children

Myopia

Taiwan
Ankara City Hospital Bilkent

Recruiting

Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric

Anesthesia | Child, Only | Cerebral Oxygenation | Cerebral Hypoxia | Inhalation; Vapor | Peripheral Oxygenation

Turkey
University of Aarhus
Aarhus University Hospital

Not yet recruiting

Effects of Exogenous Ketone Ester Supplementation on 3-hydroxybutyrate Concentrations in Human Cerebrospinal Fluid (KetoBrain)

Ketosis

Denmark
University of North Carolina, Chapel Hill
Bausch Health Americas, Inc.

Not yet recruiting

Rifaximin for the Secondary Prevention of Recurrent Pouchitis

Pouchitis

United States
University of British Columbia

Not yet recruiting

End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children

Anesthesia | Hypercapnia | Hypocapnia
Jagiellonian University

Recruiting

Activity of Chronic Inflammation in PCOS

Polycystic Ovary Syndrome

Poland
Radboud University Medical Center
Maastricht University Medical Center

Recruiting

TREAT Study - Improving the Interpretation of Troponin Concentrations Following Exercise and Their Clinical Significance (TREAT)

Coronary Artery Disease

Netherlands
Ho-Seong Han
Seoul National University Bundang Hospital

Recruiting

Diagnosis of Pancreatic Cancer by Purine Metabolite (Hypoxanthine, Xanthine) in Urine

Pancreas Cancer | Diagnosis

Korea, Republic of

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