Search clinical trials for: Tumor mutation load
Total 36367 results
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National Cancer Institute (NCI)RecruitingGlioma | Glioblastoma | Malignant Glioma | Low Grade Glioma | High Grage GliomaUnited States
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M.D. Anderson Cancer CenterActive, not recruitingPancreatic Ductal Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | KRAS NP_004976.2:p.G12DUnited States
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Sidney Kimmel Comprehensive Cancer Center at Johns...Merck Sharp & Dohme LLCActive, not recruitingHigh Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)United States
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UNICANCERAstraZeneca; National Cancer Institute, France; Pierre Fabre LaboratoriesActive, not recruitingBreast Cancer | Head and Neck Cancer | Prostate Cancer | Cervix Cancer | Advanced Solid TumoursFrance
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Quanta TherapeuticsNot yet recruitingAdvanced Solid Tumor
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AstraZenecaNot yet recruitingMetastatic Breast CancerBrazil
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Assistance Publique - Hôpitaux de ParisCentre Leon Berard; Institut National de la Santé Et de la Recherche Médicale... and other collaboratorsNot yet recruitingEnvironmental Exposure | SDH Gene Mutation | SDH-Related Familial Paraganglioma | SDHx-Related SyndromesFrance
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858 Therapeutics, Inc.RecruitingBreast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Advanced or Metastatic Solid Tumors | ER+ Breast Cancer | Castrate Resistant Prostate Cancer | BRCA MutationUnited States
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University of FloridaNot yet recruitingRecurrent GlioblastomaUnited States
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Tyligand Bioscience (Shanghai) LimitedRecruitingMalignant NeoplasmUnited States
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Jacobio Pharmaceuticals Co., Ltd.Not yet recruiting
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Jiangsu HengRui Medicine Co., Ltd.Not yet recruitingAdvanced KRAS G12D Mutant Solid TumorsChina
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Acerand Therapeutics (Shanghai) LimitedRecruitingBreast Cancer | Ovarian Cancer | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Solid Tumor, AdultChina
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Centro di Riferimento Oncologico - AvianoRecruitingNon Small Cell Lung Cancer Metastatic | ALK Gene MutationItaly
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Fujian Medical UniversityRecruitingAdvanced Hepatocellular CarcinomaChina
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University of AarhusAarhus University HospitalRecruitingPeripheral T-cell Lymphoma | NK/T-Cell LymphomaDenmark
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Shanghai Chest HospitalRecruiting
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Hunan Province Tumor HospitalNot yet recruitingNon-small Cell Lung CancerChina
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Hunan Province Tumor HospitalNot yet recruitingNon-Small Cell Lung CancerChina
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Washington University School of MedicineNational Cancer Institute (NCI); The Foundation for Barnes-Jewish HospitalRecruitingMultiple Myeloma | Rectal Cancer | Cholangiocarcinoma | Colon CancerUnited States
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Institut CurieMerck Sharp & Dohme LLC; ProLynx LLCNot yet recruiting
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationAustralia
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Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Recruiting
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Liaoning Tumor Hospital & InstituteNot yet recruitingNon Small Cell Lung Cancer
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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Ikena OncologyRecruitingColorectal Cancer | Pancreatic Cancer | Thyroid Carcinoma | Solid Tumor, Adult | Malignant Melanoma | Non-Small Cell Lung Carcinoma | BRAF Gene Mutation | Gliomas, Malignant | Ras (Kras or Nras) Gene Mutation | CRAF Gene MutationUnited States
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Shandong UniversityNot yet recruiting
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Novartis PharmaceuticalsRecruitingBRAF V600E Mutation-positive Unresectable Advanced or Recurrent Solid TumorJapan
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Iambic Therapeutics, IncRecruiting
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National Cancer Institute (NCI)RecruitingBreast Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Gastrointestinal Cancer | Genitourinary Cancer | Metastatic Solid CancersUnited States
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Sichuan Huiyu Pharmaceutical Co., LtdRecruitingEfficacy | Tolerability | SafetyChina
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Frontier Medicines CorporationRecruitingColorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C MutationsUnited States
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
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N.N. Petrov National Medical Research Center of...RecruitingMelanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene MutationRussian Federation
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Quanta TherapeuticsRecruiting
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Neogene Therapeutics, Inc.RecruitingEndometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12DUnited States
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Sarcoma Alliance for Research through CollaborationDana-Farber Cancer Institute; Cogent Biosciences, Inc.; The Life Raft GroupNot yet recruitingGastrointestinal Stromal Tumors | GISTUnited States
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IRCCS San RaffaeleUniversità Vita-Salute San RaffaeleRecruitingCarcinoma, Renal Cell | Von Hippel-Lindau DiseaseItaly
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Sixth Affiliated Hospital, Sun Yat-sen UniversityRecruitingOvarian Metastases of Colorectal CancerChina
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Hideho Okada, MD, PhDNational Cancer Institute (NCI); California Institute for Regenerative Medicine...RecruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | MGMT-Unmethylated GlioblastomaUnited States
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Cancer Institute and Hospital, Chinese Academy...Not yet recruitingNon Small Cell Lung Cancer | ERBB2 Mutation-Related Tumors | Disitamab Vedotin | ERBB2 Gene Duplication
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Hunan Province Tumor HospitalRecruitingAdvanced Lung CancerChina
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Incyte CorporationRecruitingSolid TumorsUnited States, France, Italy, Australia, Spain, Canada, Belgium
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National Cancer Institute (NCI)RecruitingLocally Advanced Chondrosarcoma | Metastatic Chondrosarcoma | Metastatic Sinonasal Adenocarcinoma | Locally Advanced Sinonasal Adenocarcinoma | Metastatic Large-cell Neuroendocrine Carcinoma | Locally Advanced Large-cell Neuroendocrine Carcinoma | Metastatic Olfactory Neuroblastoma | Locally Advanced... and other conditionsUnited States
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Pamela MunsterNational Cancer Institute (NCI)RecruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene MutationUnited States
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Revolution Medicines, Inc.RecruitingNon-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, CancerUnited States
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Rigel PharmaceuticalsNationwide Children's HospitalNot yet recruitingAstrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditionsUnited States, Australia, United Kingdom, Canada, Germany, Netherlands
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Tyra Biosciences, IncRecruitingSolid Tumor | Intrahepatic Cholangiocarcinoma | Metastatic Cholangiocarcinoma | Locally Advanced CholangiocarcinomaUnited States