Search clinical trials for: Tumour Necrosis Factor

Total 41857 results

NHS Greater Glasgow and Clyde
University of Glasgow

Recruiting

Experimental Medicine Studies of the Brain in Patients With Rheumatoid Arthritis REALISE (REALISE)

Rheumatoid Arthritis

United Kingdom
Lawson Health Research Institute
Academic Medical Organization of Southwestern Ontario

Recruiting

Advanced Therapeutics in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Canada
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Surgical Closure vs Anti-TNF in the Treatment of Perianal Fistulas in Crohn's Disease (PISA-II): a Comprehensive Cohort Design (PISA-II)

Crohn Disease | Perianal Fistula

Netherlands
Takeda

Completed

A Study to Observe Vedolizumab and Anti-tumour Necrosis Factors (Anti-TNFs) Outcomes in Real-world Biologic Ulcerative Colitis (UC) and Crohn's Disease (CD) Participants (EVOLVE-IBERIA)

Crohn Disease | Colitis, Ulcerative

Spain, Portugal
R-Pharm International, LLC
Quintiles, Inc.; OCT Clinical Trials; Mene Research

Completed

Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Were Taking an Existing Medication Called a Tumour Necrosis Factor Alpha Inhibitor But Had Active Disease (CREDO 3)

Rheumatoid Arthritis

United States, Korea, Republic of, Germany, Czechia, Mexico, Hungary, Poland, Argentina, Brazil, Colombia, Russian Federation
University Hospitals Coventry and Warwickshire...

Active, not recruiting

Obstructive Sleep Apnoea and Cardiac Arrhythmias (OSCA)

Cardiovascular Diseases | Obstructive Sleep Apnea | Arrhythmia | Atrial Fibrillation New Onset

United Kingdom
Benha University

Unknown

Glucocorticoid-induced Tumour Necrosis Factor Receptor Related Protein (GITR) in Rheumatoid Arthritis (GITR)

Rheumatoid Arthritis

Egypt
National University, Singapore

Completed

Effect of Photodynamic Therapy on Gingival Crevicular Cytokines in Periodontitis Patients

Periodontitis | Periodontal Pocket | Periodontal Attachment Loss | Periodontitis, Adult
University of Campinas, Brazil

Completed

Effects of the TNF-alpha Inhibiton on Hemodynamic Parameters in Resistant Hypertension

Hypertension

Brazil
Centre Hospitalier Universitaire de Nīmes
Pfizer

Completed

Evaluation of Tumour Necrosis Factor Alpha (TNFα) Blockers in Early Rheumatoid Arthritis in France

Rheumatoid Arthritis
Lawson Health Research Institute

Withdrawn

Tumour Necrosis Factor Release in Locally Advanced Breast Cancer Patients Receiving Neoadjuvant Docetaxel (TNFactor)

Breast Cancer

Canada
Mashhad University of Medical Sciences
Roche Pharma AG

Completed

Low Dose Rituximab as a First Line Biologic Therapy for the Treatment of DMARD Resistant Patients With Rheumatoid Arthritis

DMARD Resistant Rheumatoid Arthritis

Iran, Islamic Republic of
Hospital Regional de Alta Especialidad del Bajio
Hospital Infantil de Mexico Federico Gomez

Completed

Adipokines in Obese Adolescents With Insulin Resistance

Obesity

Mexico
Diakonhjemmet Hospital
Karolinska University Hospital; Medical University of Vienna; Oslo University... and other collaborators

Not yet recruiting

Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease Control in Adults With Rheumatoid Arthritis on a Subcutaneous TNF Inhibitor: The Rheumatoid Arthritis Therapeutic DRUg Monitoring Trial (RA-DRUM) (RA-DRUM)

Rheumatoid Arthritis

Austria, Sweden, Norway, United Kingdom
Sun Yat-sen University

Recruiting

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

Malignant Ascites

China
Marmara University

Recruiting

Therapeutic Exposures and Risk Factors in MRONJ

Medication-Related Osteonecrosis of Jaw

Turkey
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Brazilian Clinical Research Institute
Alliança Diagnostic

Not yet recruiting

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke (ARCHIMEDES)

Ischemic Stroke
Centre Hospitalier Universitaire de Saint Etienne
Direction Générale de l'Offre de Soins

Not yet recruiting

Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis (SMOOTH)

Uveitis | Chronic Disease

France
Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
Egymedicalpedia

Not yet recruiting

Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients

Plaque Psoriasis

Egypt
University of Leicester
University Hospitals, Leicester; British Heart Foundation

Recruiting

The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke (LACUNAR_CA)

Lacunar Stroke

United Kingdom
Zhongshan Ophthalmic Center, Sun Yat-sen University
The First Affiliated Hospital of Soochow University; Shandong Eye Hospital; The...

Not yet recruiting

Effect of Immunosuppressants With Adalimumab Biosimilars vs Corticosteroids on Noninfectious Uveitis

Uveitis

China
Jagiellonian University

Recruiting

Activity of Chronic Inflammation in PCOS

Polycystic Ovary Syndrome

Poland
Prof Curdin Conrad
Centre Hospitalier Universitaire Vaudois

Not yet recruiting

TYK2 Inhibition in Paradoxical Psoriasis (TYPP)

Psoriasis

Switzerland
Vastra Gotaland Region

Recruiting

Comparison Between Infliximab and Adalimumab on Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Sweden
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treatment FOr Corticosteroid Dependent UveitiS (FOCUS)

Non Infectious Uveitis
AbbVie

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participants With Active Ulcerative Colitis

Ulcerative Colitis

United States, Japan
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Study to Evaluate 608 in Patients With Ankylosing Spondylitis (AS)

Ankylosing Spondylitis

China
OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
AstraZeneca

Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Gastric Cancer | Pancreatic Adenocarcinoma | Gastroesophageal Junction Cancer

United States, Spain, United Kingdom, Korea, Republic of, Japan, Taiwan, Malaysia, Canada, Singapore, Moldova, Republic of, Australia, Georgia
Juan LI, MD

Recruiting

To Assess the Efficacy and Safety of Furmonertinib in Patients With Epidermal Growth Factor Receptor 20ins Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Non Small Cell Lung Cancer | EGFR Exon 20 Insertion Mutation

China
Centre Hospitalier Universitaire de Saint Etienne
Takeda France

Not yet recruiting

Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration. (VEDIAN)

Crohn's Disease

France
RemeGen Co., Ltd.

Recruiting

Perioperative Disitamab Vedotin Plus Toripalimab and XELOX in Gastric or Gastroesophageal Junction Adenocarcinoma.

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

China
Fusion Pharmaceuticals Inc.
AstraZeneca

Not yet recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Advanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal Carcinoma

United States, Canada
Ain Shams University

Not yet recruiting

Topical Erythropoietin Hydrogel in Management of Oral Lichen Planus

Oral Lichen Planus
Massachusetts General Hospital

Not yet recruiting

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

Inflammation | Depressive Disorder, Major
University Medical Center Groningen

Recruiting

Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease (GUIDE)

Crohn Disease | Ulcerative Colitis

Netherlands
Ottawa Hospital Research Institute

Not yet recruiting

Hyperbaric Oxygen Therapy for Perianal Fistulizing Crohn's Disease Not Responsive or Intolerant to Conventional Care: HYPNOTIC Pilot Study (HYPNOTIC)

Inflammatory Bowel Disease (IBD)
AbbVie

Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

Juvenile Psoriatic Arthritis

United States, Spain, Poland, Italy, Germany
Asan Medical Center
Samsung Medical Center; Seoul National University Hospital; Kyungpook National... and other collaborators

Recruiting

Efficacy and Safety of Formulation Switching Between SC Infliximab and IV Infliximab in Patients With CD (CHAMELEON)

Crohn's Disease

Korea, Republic of
NorthShore University HealthSystem
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effects of TNF Blockade on Human BPH/LUTS

Benign Prostatic Hyperplasia (BPH)

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
Asan Medical Center

Recruiting

TDM-based Infliximab Treatment for Active Perianal Fistulizing Crohn's Disease

Crohn Disease | Therapeutic Drug Monitoring | Infliximab | Perianal Fistula Due to Crohn's Disease | Magnetic Resonance Novel Index for Fistula Imaging in Crohn's Disease Score

Korea, Republic of
Takeda

Recruiting

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Crohn's Disease

United States
The First Hospital of Jilin University

Recruiting

Early Tirofiban Administration After Intravenous Thrombolysis in Acute Ischemic Stroke

Acute Ischemic Stroke

China
Tom Appleton
Western University; Canadian Research Group in Immuno-Oncology

Not yet recruiting

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis | Immune-related Adverse Event
IRCCS Burlo Garofolo

Recruiting

Therapeutic Monitoring of Infliximab and Adalimumab

Inflammatory Bowel Diseases

Italy
Tufts Medical Center

Not yet recruiting

Application of N-of-1 Rheumatoid Arthritis

Arthritis, Rheumatoid

United States
Zunyi Medical College

Recruiting

Century Clot-Guided Prophylactic Rivaroxaban for Post STEMI Complicating Left Ventricular Thrombus

STEMI - ST Elevation Myocardial Infarction

China

Search clinical trials for: Tumour Necrosis Factor

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