Search clinical trials for: advanced cancer

Total 94795 results

Iovance Biotherapeutics, Inc.

Not yet recruiting

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

Endometrial Cancer
West China Hospital

Recruiting

Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer

Locally Advanced Thyroid Gland Carcinoma

China
Chongqing University Cancer Hospital

Recruiting

Efficacy of Almonertinib Combined With Upfront Stereotactic Ablative Body Radiotherapy to Residual Primary Lung Lesions in Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

LM-108 Antibody Combination With Sintilimab for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (ACCLAIM)

NSCLC | PD-1

China
Qun Zhao

Recruiting

Machine Learning-driven Noninvasive Screening of Transcriptomics Liquid Biopsies for Early Diagnosis of Occult Peritoneal Metastases in Locally Advanced Gastric Cancer

1. Locally Advanced Gastric Cancer (LAGC): The Primary Condition Under Investigation is Locally Advanced Gastric Cancer, Which Refers to Stomach

China
Yunnan Cancer Hospital

Recruiting

The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial. (WINDOW)

Clinical Complete Response Rate With Negative MRD

China
Qun Zhao

Not yet recruiting

Prediction of Occult Peritoneal Metastasis of Locally Advanced Gastric Cancer Using Multimodal Data Based on Artificial Intelligence Combined With Intraoperative Dynamic Video

This Study Uses AI and Multimodal Data to Noninvasively Detect Occult Peritoneal Metastasis

China
Henan Cancer Hospital

Recruiting

Backline Treatment of Advanced Hepatocellular Carcinoma With Palbociclib

Hepatocellular Carcinoma

China
Zhejiang University

Not yet recruiting

Endoscopic Ultrasound (EUS) Intratumoral Injection of CAR-NK Cells in the Treatment of Advanced Pancreatic Cancer

Pancreatic Cancer Non-resectable
Myeloid Therapeutics

Recruiting

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

Hepatocellular Carcinoma

Australia
Fudan University

Not yet recruiting

HAIC Combined With TQB2450 and Anlotinib in Second-line Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Tang-Du Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Neoadjuvant Adebrelimab + DOS in Locally Advanced Resectable Gastric Cancer

Gastric Cancer

China
M.D. Anderson Cancer Center

Not yet recruiting

T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

Metastatic Soft-tissue Sarcoma

United States
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B16D1 in Patients With Locally Advanced or Metastatic Solid Tumors

Solid Tumor

China
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

Nasopharyngeal Carcinoma | Solid Tumor | Non-small Cell Lung Cancer

China
Bristol-Myers Squibb

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Non-small Cell Lung Cancer (NSCLC) | High-grade Serous Ovarian Carcinoma (HGSOC) | Uterine Serous Carcinoma (USC)

United States, Canada
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Peking University Cancer Hospital & Institute

Not yet recruiting

A Study of AK112 Monotherapy in Advanced/Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Esophageal Cancer

Advanced or Metastatic Esophageal Cancer

China
Zunyi Medical College

Recruiting

A Real-World Study of Pyrrolitinib Maleate Tablets for HER-2-Positive Early or Locally Advanced Breast Cancer After Adjuvant Trastuzumab Therapy

HER-2 Positive Advanced Breast Cancer

China
Mayo Clinic

Not yet recruiting

Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Advanced Prostate Cancer (CaP)

Stage III Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma | Advanced Prostate Adenocarcinoma

United States
Zhiyong Huang
Hubei Cancer Hospital; Wuhan Union Hospital, China; Renmin Hospital of Wuhan... and other collaborators

Recruiting

Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Unresectable Locally Advanced or Recurrent Metastatic Triple-negative Breast Cancer

Triple-negative Breast Cancer

China
San Luigi Gonzaga Hospital
Azienda Ospedaliera Città della Salute e della Scienza di Torino; Fondazione... and other collaborators

Recruiting

Upfront Surgery Versus NeoAdjuvant Chemotherapy Followed by Surgery for Resectable Advanced Gastric Cancer: SNAC Study (SNAC)

Gastric Cancer

Italy
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
Yuanquan Yang

Not yet recruiting

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial

Advanced Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Fudan University

Not yet recruiting

Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer

Advanced Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer

China
Tianjin Medical University Cancer Institute and...

Not yet recruiting

The Efficacy of Gemcitabine and Nab-palitaxe Combined With Cadonilimab Sequential Short-course Radiotherapy in the Treatment of Patients With Locally Advanced Pancreatic Ductal Adenocarcinoma

Locally Advanced Pancreatic Ductal Adenocarcinoma

China
Fujian Cancer Hospital

Not yet recruiting

Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
AstraZeneca
Daiichi Sankyo Company, Limited 3-5-1 Nihonbashihoncho, Chuo-ku, Tokyo

Not yet recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer (DESTINY-BTC01)

Biliary Tract Cancer

Belgium, Canada, Brazil, Japan, Korea, Republic of, Taiwan, Germany, Austria, Netherlands
Fudan University

Not yet recruiting

Enhanced vs. Routine Follow-Up After Total Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial

Quality of Life | Gastric Cancer | Postoperative Care | Follow-up | Total Gastrectomy
Xin-Hua Xu

Recruiting

A Prospective, Open-label, Single-center, Single-arm Phase II Clinical Study of Cadonilimab (AK104) Combined With Monotherapy Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer With Negative Driver Genes and Failed Immunotherapy

Non-small Cell Lung Cancer

China
MSD Italia S.r.l.

Not yet recruiting

A Study to Describe the Diagnostic and Therapeutic Path of Patients with NSCLC in Early Stage and Locally Advanced (Key-Early)

NSCLC | Non-small Cell Lung Cancer | NSCLC, Stage III | NSCLC, Stage I
Seagen Inc.

Not yet recruiting

A Study of SGN-MesoC2 in Advanced Solid Tumors

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Adenocarcinoma | Ovarian Neoplasms | Mesothelioma | Other Solid Tumors
Kumho HT Inc.

Recruiting

Study of DNP002 in Patients With Solid Tumors

Advanced Solid Tumor

Korea, Republic of
The University of Hong Kong

Not yet recruiting

Supportive Clinic for Patients Living With Advanced and Metastatic Cancers

Cancer | Physical Symptom Distress

Hong Kong
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer
AbbVie

Not yet recruiting

Study to Assess Adverse Events and How Intravenously (IV) Infused ABBV-400 Moves Through the Body of Adult Participants With Unresectable Locally Advanced/Metastatic Colorectal Cancer

Colorectal Cancer
Henan Cancer Hospital

Not yet recruiting

Clinical Study of SHR-A1921 or SHR-A2009 in Previously Treated Advanced NSCLC

NSCLC

China
Wuhan University

Not yet recruiting

A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer

Gastric Cancer

China
Genelux Corporation
Newsoara Biopharma Co., Ltd.

Not yet recruiting

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer (VIRO-25) ((VIRO-25))

Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Advanced Non-squamous Non-small-cell Lung Cancer | Non-small Cell Lung Cancer Stage IV | Metastatic Squamous Non-Small Cell Lung Carcinoma | Non-small Cell Lung Cancer Recurrent | Metastatic Non-squamous Non Small Cell Lung Cancer and other conditions
GeneQuantum Healthcare (Suzhou) Co., Ltd.

Recruiting

A Study of GQ1010 in Subjects With Advanced Solid Tumors

Advanced Malignant Solid Tumors

China
Eli Lilly and Company
Loxo Oncology, Inc.

Not yet recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (NEXUS-01)

Cervical Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Renal Pelvis Cancer | Urinary Bladder Neoplasm | Recurrent...

United States
Faeth Therapeutics
GOG Foundation

Not yet recruiting

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel, Serabelisib With Paclitaxel, and Paclitaxel Alone in Patients With Advanced/Recurrent Endometrial Cancer

Endometrial Cancer
Chengdu Baiyu Pharmaceutical Co., Ltd.

Recruiting

A Phase l Study of By101298, an Oral DNA-PK Inhibitor, in Patients With Advanced Solid Tumors

Solid Tumor, Adult

China
CytomX Therapeutics
Merck Sharp & Dohme LLC

Not yet recruiting

First In Human Study of CX-801 in Advanced Solid Tumors

Solid Tumor, Adult

United States
Guangzhou University of Traditional Chinese Medicine
Jiangsu Province Hospital of Traditional Chinese Medicine; The First Affiliated...

Not yet recruiting

Acupuncture for Enhancing Immunotherapy in Advanced NSCLC：a Pilot Study

Non-small Cell Lung Cancer | Non-Small-Cell Lung Carcinoma

China
University of Aarhus
Aarhus University Hospital

Recruiting

Proton Therapy for Locally Advanced Cervical Cancer

Cervical Cancer | Radiotherapy Side Effect | Proton Therapy

Denmark
Atish Choudhury, MD
Bayer; Pfizer; National Comprehensive Cancer Network; Sumitomo Pharma America,...

Not yet recruiting

Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)

Prostate Cancer | Advanced Prostate Cancer | Hormone Sensitive Prostate Cancer

United States
Taipei Veterans General Hospital, Taiwan
National Yang Ming Chiao Tung University

Recruiting

Exploring Physical and Psychological Needs and Quality of Life in Patients With Advanced Cancer Receiving Immunotherapy

Quality of Life | Cancer | Immunotherapy | Distress, Emotional | Financial Toxicity | IrAE | Care Need

Taiwan

Search clinical trials for: advanced cancer

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