Search clinical trials for: anti-VEGF therapy

Total 51619 results

The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central... and other collaborators

Recruiting

Brolucizumab for CNV Associated With Pathologic Myopia (COASTUAbaCNV)

Pathologic Myopia

Ukraine
University Medicine Greifswald

Recruiting

European Disease Registry on Retinopathy of Prematurity (ROP) (EU-ROP)

Retinopathy of Prematurity

Germany, Greece, Austria, Bulgaria, Estonia, France, Kosovo, Poland, Spain, Switzerland, Turkey, Ukraine
Oslo University Hospital

Completed

Zoledronic Acid as Adjuvant Therapy in Neovascular Age-related Macular Degeneration (Z-AMD) (Z-AMD)

Neovascular Age-related Macular Degeneration

Norway
Ophthotech Corporation

Terminated

Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMD

Age-related Macular Degeneration

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
The S.N. Fyodorov Eye Microsurgery State Institution

Completed

Development of an Optimal Algorithm for the Management of Patients With Retinal Pigment Epithelium Detachment in Neovascular Age-related Macular Degeneration Using Artificial Intelligence

Neovascular Age-related Macular Degeneration

Russian Federation
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central...

Completed

Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Myopia (COAST_UAmCNV)

Pathologic Myopia

Ukraine
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central...

Unknown

Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Central Chorioretinitis (COAST_UAcCNV)

Chorioretinitis

Ukraine
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central...

Unknown

Antiangiogenic Therapy of CNV Associated With Angioid Streaks (COAST_UAasCNV)

Angioid Streaks of Macula

Ukraine
National Cancer Institute (NCI)
NRG Oncology

Completed

Capecitabine, Bevacizumab, and Radiation Therapy Followed By Gemcitabine and Bevacizumab in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery

Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage II Pancreatic Cancer

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI); NovoCure Ltd.

Completed

NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Northwestern University

Terminated

Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma

United States
Taipei Veterans General Hospital, Taiwan
National Taiwan University Hospital; Chang Gung Memorial Hospital; Kaohsiung...

Completed

Efficacy and Safety of Aflibercept as Mono-therapy in Treat and Extend Regimen for DME Patients in Taiwan

Center-involved Diabetic Macular Edema
Northwestern University
Genentech, Inc.

Completed

Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Paclitaxel, Bevacizumab And Adjuvant Intraperitoneal Carboplatin in Treating Patients Who Had Initial Debulking Surgery for Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Fallopian Tube Cancer | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Brenner Tumor | Stage II Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian... and other conditions

United States, Japan
West Coast Retina Medical Group, Inc.
Genentech, Inc.

Unknown

Genetics Study of Wet Age-Related Macular Degeneration (AMD) Non-Responders to Vascular Endothelial Growth Factor (VEGF) Therapy

Wet AMD

United States
Barbara Ann Karmanos Cancer Institute
Genentech, Inc.

Completed

Bevacizumab in Treating Patients With Relapsed Prostate Cancer That Did Not Respond to Hormone Therapy

Recurrent Prostate Cancer | Stage I Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
University of California, Davis
University of California, San Francisco

Completed

ProspectiveTrial of Proton Beam Combined With Anti-VEGF Therapy for Exudative Age-related Macular Degeneration (AMD) (PBAMD2)

Exudative Age-related Macular Degeneration

United States
Barnes Retina Institute
Novartis

Completed

Use of Spectral OCT in Combination Therapy (Spectral OCT)

Choroidal Neovascularization
Novartis Pharmaceuticals

Completed

Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Branch Retinal Vein Occlusion (BRVO) (Blossom)

Macular Edema Secondary to Branch Retinal Vein Occlusion

China, Taiwan, Hong Kong, Philippines, Vietnam, Indonesia
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin) (Bevacizumab)

Diabetic Retinopathy

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Liver Metastases | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Medical University of Vienna

Terminated

The Effect of a Single Intravitreal Anti-VEGF Therapy on Optic Nerve Head Perfusion

Macular Degeneration | Vascular Endothelial Growth Factor | Regional Blood Flow

Austria
National Cancer Institute (NCI)

Completed

Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma

Ewing Sarcoma of Bone | Peripheral Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Extraosseous Ewing Sarcoma

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Cancer and Leukemia... and other collaborators

Terminated

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer

Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IV Renal Cell Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Recurrent Metastatic Squamous Neck Cancer With... and other conditions

United States
National Cancer Institute (NCI)

Completed

Bevacizumab or Cetuximab And Gemcitabine Hydrochloride, Capecitabine, and Radiation Therapy in Treating Patients With Pacreatic Cancer That Has Been Completely Removed By Surgery

Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Combination Chemotherapy in Patients With Lymph Node Positive Breast Cancer

Male Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Radiation Toxicity | Malignant Neoplasm | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the... and other conditions

United States
National Cancer Institute (NCI)

Completed

Docetaxel and Prednisone With or Without Bevacizumab in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Vitreo-Retinal Associates, PC
Genentech, Inc.

Completed

Ranibizumab in Residual Diabetic Macular Edema Following Previous Anti-VEGF Therapy

Diabetic Macular Edema

United States
National Cancer Institute (NCI)

Terminated

Bevacizumab, Paclitaxel, Carboplatin, and Radiation Therapy to the Chest in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer

Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage II Non-small Cell Lung Cancer | Adenocarcinoma of the Lung | Bronchoalveolar Cell Lung Cancer | Large Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer

Adenocarcinoma of the Rectum | Stage II Rectal Cancer | Stage III Rectal Cancer

United States
Sequenom, Inc.
Center for Eye Research and Education

Completed

Evaluation of the Association Between Genetic Load and Response to Anti-VEGF Therapy in AMD Patients (EVERGREEN)

Age Related Macular Degeneration

United States
National Cancer Institute (NCI)

Completed

Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma... and other conditions

United States
National Cancer Institute (NCI)

Completed

Radiation Therapy, Bevacizumab, Paclitaxel, and Carboplatin in Treating Patients With Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer at High Risk for Hemoptysis Caused by Bevacizumab

Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Drug/Agent Toxicity by Tissue/Organ | Adenosquamous Cell Lung Cancer | Hemoptysis
Sudhalkar Eye Hospital

Completed

Comparison of Subconjuctival Versus Topical Bevacizumab as Adjunct Therapy to Trabeculectomy

Progression | Complications of Treatment
University Hospital Inselspital, Berne
Novartis

Completed

Immediate Effects of Lucentis® in Conjunction With Photodynamic Therapy With Visudyne® in Exudative AMD(IECOMB)

Age Related Macular Degeneration

Switzerland
University of Miami
Medtronic

Not yet recruiting

STARLITE for Unresectable High-Grade Gliomas (STARLITE)

High Grade Glioma

United States
Omer Ayhan

Recruiting

Fully Immersive Virtual Reality Applications in Children With Cerebral Palsy

Cerebral Palsy

Turkey
Massachusetts General Hospital
American Heart Association

Recruiting

Impact of Cognitive Behavioral Therapy on PTSD-CVD Link

Posttraumatic Stress Disorder

United States
University of Kansas Medical Center

Not yet recruiting

Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis (CALM)

Multiple Sclerosis | Insomnia
Shandong Qilu Stem Cells Engineering Co., Ltd.
Qilu Children's Hospital of Shandong University

Recruiting

Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases

Bronchopulmonary Dysplasia | Hypoxic-Ischemic Encephalopathy | Short Bowel Syndrome

China
University of Hail

Not yet recruiting

Decompression Versus Heat and Decompression in Knee OA

Knee Osteoarthritis

Saudi Arabia
Universidad Nacional Andres Bello

Not yet recruiting

Functional and Neuroplastic Effects of HABIT-ILE in Children With Bilateral Cerebral Palsy (FuN HABIT-ILE)

Cerebral Palsy

Chile
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Shenzhen Geno-Immune Medical Institute
The No.2 Clinical Hospital of the Ministry of Health

Recruiting

Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma

Multiple Myeloma | Plasmacytoma

China, Russian Federation

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