Search clinical trials for: arginine deiminase pegylated

Total 1480 results

M.D. Anderson Cancer Center

Recruiting

Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC)

Prostate Cancer

United States
Chang Gung Memorial Hospital

Recruiting

Phase 2 Study of ADI-PEG 20 Plus Lenvatinib Treatment in Subjects With Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

Taiwan
Washington University School of Medicine
Polaris Group

Recruiting

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Soft Tissue Sarcoma | Sarcoma,Soft Tissue | Sts

United States
Washington University School of Medicine
Polaris Group

Recruiting

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Small Cell Lung Carcinoma | Non Small Cell Lung Cancer | Non-small Cell Lung Cancer | Small-cell Lung Cancer

United States
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer

Soft Tissue Sarcoma

United States
M.D. Anderson Cancer Center

Withdrawn

Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver Cancer

Resectable Hepatocellular Carcinoma

United States
Ludwig Institute for Cancer Research
Memorial Sloan Kettering Cancer Center; National Taiwan University Hospital; Duke... and other collaborators

Terminated

Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Taiwan, Germany, Belgium, United Kingdom
Polaris Group

Completed

Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer

Prostate Cancer | Solid Tumors

United States
University of Miami

Completed

Pegylated Arginine Deiminase in Treating Patients With Metastatic Melanoma That Cannot Be Removed by Surgery

Melanoma (Skin)

United States
Polaris Group

Completed

Ph 1 Study of ADI PEG 20 in Pediatric Subjects Who Are Argininosuccinate Synthetase (ASS) Deficient

Argininosuccinate Synthetase Deficient

United States
Polaris Group

Recruiting

Study of ADI-PEG 20 Versus Placebo in Subjects With NASH

Nonalcoholic Steatohepatitis (NASH)

Taiwan
Polaris Group

Recruiting

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

Soft Tissue Sarcoma

United States, Taiwan, Canada
Polaris Group

Recruiting

Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Advanced Hepatocellular Carcinoma

Taiwan, Vietnam
Polaris Group

Recruiting

ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme (GBM)

Taiwan
University of Birmingham

Completed

A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) (PARC)

Cancer | Pediatric ALL | Pediatric Solid Tumor | Pediatric AML

United Kingdom, Australia, Netherlands
Polaris Group

Terminated

Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Advanced Gastrointestinal (GI) Malignancies

United States, Taiwan, Korea, Republic of, United Kingdom, China, Italy
Polaris Group

Completed

PH 2 ADI-PEG 20 Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Taiwan
Polaris Group

Completed

Ph 1B Trial With ADI-PEG 20 Plus Nab-Paclitaxel and Gemcitabine in Subjects With Pancreatic Cancer

Advanced Pancreatic Cancer

United States
Polaris Group

Terminated

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (TRAP)

Glioma | Hepatocellular Carcinoma | Uveal Melanoma | Sarcomatoid Carcinoma | Pleural Mesothelioma Malignant Advanced | Peritoneal Mesothelioma Malignant Advanced | Non-squamous Non-small Cell Lung Carcinoma

United States, United Kingdom
Bio-Cancer Treatment International Limited
Oncotherapeutics

Completed

Recombinant Human Arginase 1 (rhArg1) in Patients With Advanced Arginine Auxotrophic Solid Tumors

Melanoma | Prostate Adenocarcinoma

United States
University of Copenhagen
Copenhagen University Hospital, Denmark

Completed

Interaction Between Immune Cells and Bacteria Associated With Periodontitis

Inflammation | Rheumatoid Arthritis | Periodontitis | Periodontal Diseases | Dysbiosis | Aggressive Periodontitis | Chronic Periodontitis | Periodontal Pocket | Generalized Chronic Periodontitis | Microbial Disease | Inflammation Gum | Immunologic Disease | Generalized Aggressive Periodontitis

Denmark
Sanjiv Sam Gambhir
National Cancer Institute (NCI)

Completed

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Tongue Cancer | Stage... and other conditions

United States
Polaris Group

Completed

Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy (ADI-PEG 20)

Hepatocellular Carcinoma

United States, Korea, Republic of, Taiwan, Italy, United Kingdom, China
Polaris Group

Completed

PH 2 ADI-PEG 20 Study in Non-Hodgkin's Lymphoma Subjects Who Have Failed Prior Systemic Therapy

Non-Hodgkin's Lymphoma

Taiwan
Polaris Group

Completed

Ph 2 Trial of ADI PEG 20 Plus Concurrent Transarterial Chemoembolization (TACE) Vs TACE Alone in Patients With Unresectable Hepatocellular Carcinoma (TACE)

Unresectable Hepatocellular Carcinoma

Taiwan
Polaris Group

Completed

Ph 1 Trial of ADI PEG 20 Plus Sorafenib to Treat Patients With Liver Cancer

Hepatocellular Carcinoma

United States
Polaris Group

Completed

Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma

Cutaneous Melanoma, Uveal Melanoma, Ovarian Carcinoma or Other Advanced Solid Tumors

Taiwan, United States
FDA Office of Orphan Products Development

Completed

ADI-PEG in Patients With Metastatic Melanoma

Melanoma | Neoplasm Metastasis

United States
ITM Solucin GmbH

Not yet recruiting

Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors (KinLET)

Lymphoma | CNS Tumor | Solid Tumor, Childhood | Somatostatin Receptor Positive | NET
Istituti Clinici Scientifici Maugeri SpA

Not yet recruiting

Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation.

Chronic Obstructive Pulmonary Disease | Respiratory Failure

Italy
Roswell Park Cancer Institute

Not yet recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Locally Advanced Unresectable Triple-Negative Breast Carcinoma

United States
The Cleveland Clinic

Not yet recruiting

Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator

Shock, Septic
Celgene

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (GOLSEEK-2)

Lymphoma, Follicular

United States, Australia, Brazil, Canada, Chile, France, Germany, Italy, Korea, Republic of, Poland, Spain, Taiwan, United Kingdom
Hospital Universitario 12 de Octubre

Not yet recruiting

Registry of Patients in Shock Treated With Vasopressin

Shock | Vasopressor Adverse Reaction | Vasopressin Causing Adverse Effects in Therapeutic Use | Vasopressin Deficiency

Spain
The University of Texas Medical Branch, Galveston
The University of Texas Health Science Center, Houston; MOUNT SINAI HOSPITAL

Not yet recruiting

Tranexamic Acid in Vaginal Reconstructive Surgery (TEXAS)

Pelvic Organ Prolapse

United States
Beni-Suef University

Not yet recruiting

Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients

Polycystic Ovary Syndrome

Egypt
Universidade Estadual Paulista Júlio de Mesquita...

Recruiting

EFFECTS OF L-ARGININE SUPPLEMENTATION ON THE RECOVERY OF CARDIORESPIRATORY PARAMETERS AFTER SUBMAXIMAL EXERCISE TEST

Nutrition, Healthy

Brazil
Chinese PLA General Hospital

Recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma

China
Indonesia University
Universitas Padjadjaran; Fakultas Kedokteran Universitas Indonesia; Institut... and other collaborators

Not yet recruiting

The Effect of Anthocyanin Intake From Purple Sweet Potato in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
Tufts University
Colgate Palmolive

Recruiting

Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine

Xerostomia

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial)

Acute Kidney Injury Post Liver Transplantation

France
Population Health Research Institute

Not yet recruiting

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial (BRACKETS)

Chronic Kidney Diseases | Bleeding | Surgery | Acute Kidney Injury
National University Hospital, Singapore

Recruiting

Ma-Spore ALL 2020 Study

B Lymphoblastic Leukemia

Malaysia, Singapore
University of Electronic Science and Technology...

Recruiting

The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study

Healthy

China
University of Electronic Science and Technology...

Recruiting

Oral Vasopressin Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study

Healthy

China
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
Qing XIe

Recruiting

Pegylated Interferon α in Previously Interferon-treated CHB（Leading Study）

Chronic Hepatitis b

China
Al-Azhar University

Not yet recruiting

Vasopressin Versus Tranexamic Acid for Control of Blood Loss Related to Abdominal Hysterectomy

Uterine Surgery
Al-Azhar University

Recruiting

Desmopressin Monotherapy for Monosymptomatic Nocturnal Enuresis

Nocturnal Enuresis

Egypt

Search clinical trials for: arginine deiminase pegylated

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