Search clinical trials for: cardiovascular safety

Total 101101 results

Emory University
The Marcus Foundation

Not yet recruiting

A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)

Dilated Cardiomyopathy

United States
ResoTher Pharma

Recruiting

An Exploratory, Randomised, Double-blind Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI)

ST Elevation Myocardial Infarction

Denmark
Emory University
University of California, San Diego; Ventrix, Inc.

Not yet recruiting

Study of Intramyocardial Injection of Ventrix Bio Extracellular Matrix (VentriGel) to Assess the Safety and Feasibility in Pediatric Patients With Hypoplastic Left Heart Syndrome (HLHS)

Hypoplastic Left Heart Syndrome

United States
Inozyme Pharma

Not yet recruiting

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Pseudoxanthoma Elasticum | Arterial Calcification | Gene Mutations | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency | Autosomal Recessive Hypophosphatemic Rickets Type 2
Xuanwu Hospital, Beijing
Beijing Tiantan Hospital; Qilu Hospital of Shandong University; The Affiliated... and other collaborators

Recruiting

Pipeline Embolization Device for the Treatment of Intracranial Aneurysms on the Long Term Safety and Efficacy

Treatment

China
MicroPort CRM

Not yet recruiting

Safety and Performance Evaluation of a New Catheter Range for Lead Implantation at Interventricular Septum (POLARIS)

Bradycardia | Cardiac Resynchronization Therapy | Left Bundle Branch Area Pacing
Khondrion BV

Not yet recruiting

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases (KH176-301)

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
Regional Cardiology Center, The Copper Health Centre...
Department of Cardiology, Provincial Specialized Hospital in Legnica, 59-200...

Recruiting

Lower Silesian Orbital Atherectomy Registry (LOAR) (LOAR)

Safety Issues | Efficacy, Self

Poland
Corina Schuster-Amft

Not yet recruiting

Feasibility, Safety and Performance Evaluation of an Application Based Training Programme for Patients After a Stroke (TeleRehaStroke)

Stroke

Switzerland
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial

Acute Ischemic Stroke

China
Penumbra Inc.

Recruiting

Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan (JapanIndigoPMS)

Arterial Occlusion Mesenteric Artery Superior | Acute Limb Ischemia | Acute DVT of Lower Extremity

United States
NovoBliss Research Pvt Ltd
Winnox Cosmeceutics Sdn. Bhd

Not yet recruiting

A Clinical Study to Determine the Safety and Efficacy of Bio-Ray Knee Guard in Panelists With Varicose Vein and Knee Pain.

Varicose Veins With Self-declared Knee Pain
Addpharma Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B

Essential Hypertension
Hanmi Pharmaceutical Company Limited

Recruiting

A Study to Evaluate Efficacy and Safety of HCP1803 Compared to RLD2001-1 in Patients With Essential Hypertension (HM_APOLLO)

Hypertension

Korea, Republic of
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
ID3 Medical
Abbott; Vascular Science LP GmbH

Not yet recruiting

Investigating Efficacy and Safety of JETi® in Arterial Occlusions in FEM-POP and Prox BTK-Lesions (JETART) (JETART)

Peripheral Arterial Disease
Opna Bio LLC

Not yet recruiting

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Octapharma

Not yet recruiting

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Significant Bleeding Risk | Vitamin K-Dependent Coagulation Defect
Chong Kun Dang Pharmaceutical

Recruiting

Efficacy and Safety of Telmisartan Compared With Losartan

Hypertension | Diabetic Nephropathies

Korea, Republic of
Pharmosa Biopharm Inc.
Novotech (New Zealand) Limited

Not yet recruiting

Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults

Pulmonary Arterial Hypertension

New Zealand
Boston Children's Hospital

Not yet recruiting

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Beijing Tiantan Hospital

Not yet recruiting

Efficacy and Safety of Chinese Herbal Formula HuoXue LiShui for Chronic Subdural Hematoma (CHARM)

Chronic Subdural Hematoma

China
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
Tanta University

Not yet recruiting

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Egypt
Ewha Womans University Seoul Hospital

Not yet recruiting

Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.

Stroke | Atherosclerosis
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
AJU Pharm Co., Ltd.

Recruiting

Efficacy and Safety of AJU-C52 in Essential Hypertension Patients

Essential Hypertension

Korea, Republic of
Translumina Therapeutics LLP
Iqvia Pty Ltd

Recruiting

A Multicenter Observational Registry to Evaluate Safety and Performance of Vivo ISAR (SECURE Global Registry)

Cardiovascular Diseases

India, Italy, Netherlands
Xuanwu Hospital, Beijing

Not yet recruiting

Long-term Procedural and Device Related Complications of PFO Closure

Patent Foramen Ovale
Li Xiaorong
Shanghai Refreshgene Technology Co., Ltd.

Recruiting

The Preliminary Safety and Efficacy of RRG001 After Vitrectomy in Subjects With Proliferative Diabetic Retinopathy (PDR)

PDR - Proliferative Diabetic Retinopathy

China
Huashan Hospital

Recruiting

The Effectiveness and Safety of Body Posture in Preventing Postoperative Recurrence for Chronic Subdural Hematoma

Recurrence | Chronic Subdural Hematoma

China
East and North Hertfordshire NHS Trust
Professor Eliano Navarese (Co-Principal Investigator)

Not yet recruiting

Safety of AI-Powered Virtual Assistant in Outpatient Management of Heart Failure

Heart Failure
Celgene
Bristol-Myers Squibb

Recruiting

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation (KarMMa-9)

Multiple Myeloma

Austria, United States, Spain, Australia, Japan, France, Israel, Italy, Canada, Greece, Belgium, Norway, Romania, Czechia, Denmark, Germany, Korea, Republic of, United Kingdom, Poland
Neurotech Pharmaceuticals

Not yet recruiting

A Study to Determine the Safety and Efficacy of NT-501 With MHFM

Macular Telangiectasia Type 2

United States
Shanghai Zhongshan Hospital

Not yet recruiting

The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis

Glucocorticoid Resistant ICIs-related Myocarditis
Laboratoires Thea

Not yet recruiting

Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
China National Center for Cardiovascular Diseases

Recruiting

Efficacy and Safety of Thoracoscopic Morrow Surgery in the Treatment of Hypertrophic Obstructive Cardiomyopathy

Minimally Invasive Surgery | Cardiomyopathy, Hypertrophic Obstructive

China
Cerenovus, Part of DePuy Synthes Products, Inc.

Not yet recruiting

Safety, Performance of CEREGLIDE 92 Intermediate Catheter in Treatment of Acute Ischemic Stroke (SPLENDID)

Acute Ischemic Stroke

United States
AstraZeneca
Parexel

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral AZD0233 Compared With Placebo in Healthy Adult Participants.

Dilated Cardiomyopathy

United States
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
B.Braun Avitum AG

Recruiting

Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis

Renal Dialysis

Italy
Pediatric Clinical Research Platform
University Hospital, Geneva

Not yet recruiting

Performance and Safety of the Pneumoscope Device in Adults and Children

Pneumonia | Asthma | Respiratory Diseases | Cyanotic Heart Disease

Switzerland
yilong Wang

Recruiting

The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Treatment of Acute Large Hemispheric Infarction (SOLUTION-2)

Stroke, Acute Ischemic | Blood-Brain Barrier

China
Anaconda Biomed S.L.

Not yet recruiting

Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA5 Device (ATHENA)

Acute Ischemic Stroke From Large Vessel Occlusion
The People's Hospital of Gaozhou

Recruiting

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

China
Capital Medical University

Not yet recruiting

Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment

Idiopathic Intracranial Hypertension
Medical University of Vienna
Ludwig Boltzmann Institute Digital Health and Patient Safety

Recruiting

Tele-Support for Emergency Medical Technicians (POHCA)

Cardiac Arrest

Austria
Akura Medical

Not yet recruiting

Safety and Effectiveness of the Akura Thrombectomy System in the Treatment of Acute Pulmonary Embolism

Pulmonary Embolism Acute

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