Search clinical trials for: centrally acting mediators of satiety

Total 429480 results

University of New Mexico

Completed

Insulin Detemir Compared to Insulin Glargine: Appetite and Calories Consumed in Type 1 Diabetes

Diabetes Mellitus

United States
University of Ulster
Federico II University

Recruiting

Bioavailability of N-acylethanolamines: an Ileostomy Study (NAE Study) (NAE)

Healthy Nutrition

United Kingdom
Northwell Health
Lupus Research Alliance

Recruiting

Centrally Acting ACE Inhibition in SLE

Systemic Lupus Erythematosus

United States
Karolinska Institutet

Completed

Effects of Insulin Treatment on Postprandial Platelet Activation in Patients With Non-insulin-dependent Diabetes Mellitus (NIDDM)

Type 2 Diabetes Mellitus | Postprandial Hyperglycemia

Sweden
Tris Pharma, Inc.

Completed

Painful Diabetic Polyneuropathy Trial With a New Centrally Acting Analgesic

Diabetic Polyneuropathy

Germany, United Kingdom
Imperial College London
Aristotle University Of Thessaloniki

Completed

Anti-hypertensive Medication Dosing Regimen in Effective Blood Pressure Control (HARMONY)

Hypertension

Greece, United Kingdom
Maastricht University Medical Center

Completed

Early Vascular Adjustments to Prevent Preeclampsia

Preeclampsia | HELLP Syndrome | Small for Gestational Age at Delivery

Netherlands
Grünenthal GmbH

Completed

Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and Pregabalin

Low Back Pain | Neuropathic Pain

Austria, Belgium, Denmark, Germany, Netherlands, Poland, Spain
Grünenthal GmbH

Completed

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular Analgesic

Osteoarthritis | Chronic Pain

Germany, United Kingdom, France, Poland, Spain
Grünenthal GmbH

Terminated

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.

Osteoarthritis | Chronic Pain

Germany, United Kingdom, Spain, Australia, Denmark, Poland
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Pain | Knee Osteoarthritis

Austria, Croatia, Germany, Hungary, Italy, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Spain, United Kingdom
Grünenthal GmbH

Completed

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics

Low Back Pain | Chronic Pain

Austria, Germany, United Kingdom, Croatia, France, Italy, Poland, Spain, Switzerland
Grünenthal GmbH

Terminated

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability

Pain | Low Back Pain | Chronic Pain | Neuropathic Pain | Nociceptive Pain

Belgium, Czechia, France, Germany, Netherlands, Poland, Spain, Switzerland
St George's, University of London
Rosetrees Trust

Completed

Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin (DUPRO)

Hand Osteoarthritis

United Kingdom
Grünenthal GmbH

Terminated

Multiple Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations

Healthy

Germany
Grünenthal GmbH

Terminated

Single Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations (Protocol ID 297307)

Healthy

Germany
Grünenthal GmbH

Terminated

Multiple Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations (Protocol ID: 855509)

Healthy

Germany
Grünenthal GmbH

Terminated

Single Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations

Healthy

Germany
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
Belgian Research on AIDS and HIV Consortium

Not yet recruiting

Use of Long-Acting Injectable Cabotegravir/Rilpivirine for the Treatment of HIV in Belgium

Human Immunodeficiency Virus
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
Yale University
ViiV Healthcare

Not yet recruiting

Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs

Hiv

United States
Universidad de Granada

Not yet recruiting

Impact of Methylxanthine Intake and Blue Light Exposure on Adhesive Shoulder Capsulitis.

Adhesive Capsulitis of Shoulder

Spain
University of Zurich
Swiss HIV Cohort Study

Recruiting

Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures

HIV Infections

Switzerland
University Paris 7 - Denis Diderot
Hopital Foch

Not yet recruiting

Patient-Reported Outcomes in Real-life of Cabotegravir and Rilpivirine (PANTER)

Quality of Life
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Supporting Oral and Long-acting PrEP Decision Making Among Pregnant Women in Lilongwe, Malawi

HIV Prevention

Malawi
Sanofi Pasteur, a Sanofi Company

Recruiting

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers (CORAL)

RSV Immunization

United States
GlaxoSmithKline

Recruiting

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Asthma

United States, Canada, Argentina, Australia, Japan, Korea, Republic of, Taiwan
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy

Pregnancy | HIV-1-infection | Postpartum

United States, South Africa
Walton Centre NHS Foundation Trust
University of Liverpool; National Institute for Health Research, United Kingdom

Not yet recruiting

Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage (RESTARTtlCrH)

Traumatic Intracranial Haemorrhage
Georgetown University
Johns Hopkins Bloomberg School of Public Health; United States Agency for International... and other collaborators

Recruiting

PathToScale: An Implementation Evaluation

Oral Pre-exposure Prophylaxis (PrEP) | Long-acting Injectable Cabotegravir for PrEP

Malawi
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
AstraZeneca
Parexel

Recruiting

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma (ACADIA)

Asthma

United States
Applied Science & Performance Institute

Recruiting

The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States

Cognitive Change | Mood Change | Mental Processes

United States
AstraZeneca

Recruiting

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
University of California, San Francisco
Agency for Healthcare Research and Quality (AHRQ); Essential Access Health

Recruiting

Patient-centered Information on Permanent Contraception

Contraception | Contraception Behavior | Reproductive Behavior

United States
Novo Nordisk A/S

Recruiting

A Study to Test How a New Long-acting Insulin Works in the Body of Patients With Type 2 Diabetes During Exercise and Prolonged Fasting

Diabetes Mellitus, Type 2

Austria
University of Illinois at Urbana-Champaign
Kenneth Dallmier Consulting, LLC

Recruiting

The Effect of the Inclusion of Soybean Flour on Glycemic Responses

Overweight and Obesity

United States
Latticon Antibody Therapeutics, Inc

Not yet recruiting

A First-in-Human, Phase 1/2 Study of LAT010 in Patients With Advanced Solid Tumors (LIGHTSPEED-1) (LIGHTSPEED-1)

Advanced Solid Tumor

United States
ANRS, Emerging Infectious Diseases

Not yet recruiting

Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France. (CABOPrEP)

Prevention

France
Assiut University

Recruiting

Postpartum Initiation of Long-acting Reversible Contraceptives: Knowledge Attitude and Practice Study (KAP) (KAP)

Contraception

Egypt
University of Colorado, Denver
Congressionally Directed Medical Research Programs

Recruiting

Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis (Frostbite)

Frostbite

United States
University of Bordeaux

Recruiting

Introduction of Long Acting Buprenorphine in France (OBAP)

Addiction Opiate

France
Africa Health Research Institute

Recruiting

Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT (LAPIS)

HIV Infections

South Africa
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Not yet recruiting

QSPainRelief-STRAT (QSPR-STRAT)

Chronic Pain | Analgesia | Adverse Drug Event | Drug Interaction
Saglik Bilimleri Universitesi

Not yet recruiting

Effect of Conservative Root Canal Instrumentation on the Release of Inflammatory Mediators in Root Canal Treatments

Irreversible Pulpitis
Next Biomedical Co., Ltd.

Recruiting

SHEPHERD(SHort-acting Embolization Particles for Patients With HEpatocellular Carcinoma Treated by RaDioembolization)

Hepatocellular Carcinoma

Korea, Republic of
Hôpital NOVO

Recruiting

Assessment of a Procedure for Managing Oral Anticoagulants (NACO) in the Management of Fractures (STOP-NACO)

Femur Fracture

France
Abbott

Recruiting

Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia

Functional Dyspepsia

Malaysia, Armenia

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