Search clinical trials for: clinical high risk (CHR)

Total 85651 results

Rhode Island Hospital

Recruiting

A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis

Psychosis Nos/Other

United States
GlaxoSmithKline

Terminated

Phase 1 Dose Escalating Study to Assess Safety, Tolerability, Food Effect and PK of CHR-5154 in Healthy Male Volunteers

Arthritis, Rheumatoid

United Kingdom
Icahn School of Medicine at Mount Sinai
National Institute of Mental Health (NIMH)

Recruiting

Telehealth Cognitive Behavioral Therapy for Youth at Risk for Psychosis

Clinical High Risk for Psychosis (CHR)

United States
Centre for Addiction and Mental Health

Recruiting

Effects of NAC on Symptoms of CHR Patients

Prodromal Schizophrenia

Canada
Wissenschaftliches Institut Bethanien e.V

Completed

Inspiratory Muscle Training During Right-heart Catheterization

Respiratory Muscle Training | Right-heart Hemodynamics | Inspiratory Resistance

Germany
Chr Hansen

Completed

Mapping the MoA Behind GI Protection From Bif195 (PIP-M)

Reduction of Small Intestinal Ulceration Risk

Denmark
Chr Hansen

Completed

The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage (PIP-I)

Reduction of Small Intestinal Ulceration Risk

United States
Icahn School of Medicine at Mount Sinai
National Institute of Mental Health (NIMH)

Enrolling by invitation

Reducing the Duration of Untreated Psychosis in the United States: The Impact of Screening and Systematic Communication (EaSIE)

First Episode Psychosis (FEP) | Clinical High Risk for Psychosis (CHR)

United States
Chr Hansen

Completed

Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population

Inflammation

Ireland
AdAlta Limited

Completed

Safety, Tolerability, PK and PD Study of AD-214 Administered to Healthy Volunteers and Patients With Interstitial Lung Disease or Chronic Kidney Disease

Chronic Kidney Diseases | Interstitial Lung Disease

Australia
AdAlta Limited

Completed

Phase 1 Safety, Tolerability, PK & PD Study of AD-214 Administered to Healthy Volunteers

Interstitial Lung Disease

Australia
University of California, Irvine
University of Maryland, Baltimore County

Not yet recruiting

Youth Nominated Support Team (YST)

Suicide | Psychosis | Health Care Utilization | Family Members
Sosei

Completed

A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia

Fibromyalgia

United Kingdom
University of California, Los Angeles

Enrolling by invitation

Feasibility Trial of a Lifestyle Intervention for CHR-P

Psychosis | Prodromal Schizophrenia | Psychological Stress | Psychological Disorder

United States
Chroma Therapeutics

Completed

Safety and Tolerability of CHR-2845 to Treat Haematological Diseases or Lymphoid Malignancies (CHR-2845-001)

Lymphoid Malignancies | Hematological Disease

France, Belgium, Netherlands
University of British Columbia
Canadian Institutes of Health Research (CIHR); University of Victoria; Provincial... and other collaborators

Completed

Evaluating the Effectiveness of the Dissemination of Action Schools! BC (AS!BC)

Obesity | Physical Activity | Physical Fitness

Canada
Chr Hansen

Completed

Effect of Probiotics on Stress in Young Adults

Stress

Ireland
Chr Hansen

Completed

Effect of Two Probiotic Formulations on Mental Health and Mood Biomarkers in Adults With Depressive Symptoms

Depression, Anxiety

Australia
Pierre Fabre Medicament

Completed

Efficacy on Volume Reduction and Tolerance of Progressiv' Medical Compressive Therapy (MCT) V0322 BC in Patients With Chronic Venous Oedema

Chronic Venous Insufficiency (CVI)

France
Rush University Medical Center
Harvard Medical School (HMS and HSDM); National Institute of Mental Health... and other collaborators

Completed

Targeted Cognitive Training in Clinical High Risk (CHR) for Psychosis

Clinical High Risk for Psychosis

United States
Istituto Auxologico Italiano
YGHEA, CRO Division of Ecol Studio spa; Apnimed Inc.; STM Pharma PRO srl

Completed

Study of AD128 Versus Placebo in Obstructive Sleep Apnea

Obstructive Sleep Apnea

Italy
Centre for Addiction and Mental Health

Recruiting

Optimizing Mental Health for Young People at Clinical High Risk for Psychosis (CHR)

Psychosis | Psychosocial Functioning

Canada
Children's Mercy Hospital Kansas City

Withdrawn

Calcimimetics in Hypophosphatemic Rickets (CHR)

Familial Hypophosphatemic Rickets

United States
Addpharma Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of AD-218

Mixed Dyslipidemia

Korea, Republic of
Addpharma Inc.

Completed

A Study to Evaluate the Efficacy and Safety of AD-203

Acute Gastritis | Chronic Gastritis

Korea, Republic of
Weill Medical College of Cornell University
CTI BioPharma

Completed

Study of Clinical Efficacy and Safety of Tosedostat in MDS (IST-CTI-MDS)

Myelodysplastic Syndrome

United States
University Hospital, Bonn
Charite University, Berlin, Germany; Heinrich-Heine University, Duesseldorf; University... and other collaborators

Terminated

"Multimodal Prevention of Psychosis - Investigating Efficacy of N-Acetylcysteine and Psychotherapy in CHR-Patients" (ESPRIT-B1)

Prodromal Schizophrenia

Germany
Apnimed

Recruiting

Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)

OSA

United States, Canada
Apnimed

Active, not recruiting

Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)

OSA

United States
Sosei
Novartis

Completed

A Study to Assess the Safety and Efficacy of Different AD 237 Doses in Adults With COPD

COPD

Bulgaria, Poland, Hungary, Romania
Apnimed

Completed

Crossover Trial of AD182 and AD504 in Obstructive Sleep Apnea

Obstructive Sleep Apnea

United States
Apnimed

Not yet recruiting

Study That Tests AD109 in Patients Taking GLP-1 Drugs

OSA

United States
University of California, Los Angeles
National Institute of Mental Health (NIMH)

Recruiting

Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial

Psychotic Disorders | Psychosis | Prodromal Schizophrenia | Prodromal Symptoms | Family

United States, Canada
Chroma Therapeutics

Unknown

Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
TNO
Chr Hansen

Completed

Effect of Nutritional Interventions on Inflammatory Status in Healthy Overweight Men

Cardiovascular Disease | Diabetes | Overweight

Netherlands
Assiut University

Unknown

Chemoradiotherapy for Recurrent T1G3 Bladder Cancer

Bladder Cancer
Centre Hospitalier Régional d'Orléans

Completed

Volumetric Bone Mineral Density and it's Relationship With Osteoporotic Fractures in Parkinson's Disease (DOPPA)

Idiopathic Parkinson's Disease

France
Centre Hospitalier Régional d'Orléans

Recruiting

Validation of the Apnea Test Performed by High-flow Oxygen Therapy in Patients With Clinical Brain Death (APNEAFLOW)

Brain Death

France
Centre Hospitalier Régional d'Orléans

Completed

High Flow Oxygen During Spontaneous Breathing Trial in Patients With High Weaning Risk Failure: Impact on the Weaning Course at D7 From the First Spontaneous Breathing Trial. (ObiWEAN)

Mechanical Ventilation | Mechanical Ventilator Weaning | Endotracheal Extubation

France
Chroma Therapeutics

Completed

Safety and Anti-Disease Activity of CHR-2797 (Tosedostat) in Elderly and/or Treatment Refractory Patients With Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Acute Myeloid Leukemia | Multiple Myeloma | Myelodysplastic Syndrome

United Kingdom
Northwell Health
National Institute of Mental Health (NIMH)

Recruiting

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk (SCORES)

Psychosis | Prodromal Schizophrenia | Prodromal Symptoms

United States
Addpharma Inc.

Completed

A Study to Evaluate the Safety and Pharmacokinetics of AD-221 Compared to Coadministration of AD-221A and AD-221B

Hyperlipidemias

Korea, Republic of
Chr Hansen
Atlantia Food Clinical Trials

Terminated

The Effect of a Probiotic Strain on Aspirin-induced GI Damage (PIP-L)

Reduction of Small Intestinal Ulceration Risk

United States
CTI BioPharma
Chroma Therapeutics

Completed

Crossover Trial of the Effect of a High-Fat Meal on the PK of Oral CHR 2797 in Healthy Male Subjects (8265134)

Healthy

United States
Chroma Therapeutics
Institute of Cancer Research, United Kingdom

Completed

Safety Study to Evaluate CHR-2797 in Patients With Advanced Tumours

Advanced Solid Tumors
University of Calgary
National Alliance for Research on Schizophrenia and Depression

Completed

Effects of Cognitive Remediation on Cognition in Young People at Clinical High Risk of Psychosis

Prodromal Schizophrenia
Ryerson University
Chr Hansen

Completed

Effect of Probiotics on GBS Colonization Status During Pregnancy: A Pilot Randomized Controlled Trial

Group B Streptococcal Infection

Canada
Universitat Internacional de Catalunya

Completed

Regenerative Combined Therapy With Enamel Matrix Derivative and Biphasic Calcium Phosphate Graft

Intrabony Periodontal Defect
Hvidovre University Hospital
Chr Hansen

Completed

Probiotic Efficacy in VRE Eradication (PROVE)

VRE Colonization

Denmark
Chr Hansen
University of Copenhagen

Completed

Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children (PiP-C)

Dental Caries

Denmark

Search clinical trials for: clinical high risk (CHR)

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