Search clinical trials for: clinical safety and efficacy

Total 475193 results

Arthrosi Therapeutics

Recruiting

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, Australia, New Zealand
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial

Carpal Tunnel Syndrome | Surgery | Ultralsound-Guide

China
MediLink Therapeutics (Suzhou) Co., Ltd.

Not yet recruiting

A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC

Locally Advanced or Metastatic Breast Cancer

China
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Jazz Pharmaceuticals

Not yet recruiting

A Phase 3, Randomized, Open-label, Controlled Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Metastatic HER2-positive Breast Cancer
Hospital San Carlos, Madrid

Recruiting

Efficacy and Safety of Atropine and DIMS Lenses in Controlling Myopia in Children: A Randomized Clinical Trial. (DIMS)

Myopia

Spain
Ascendis Pharma Growth Disorders A/S

Not yet recruiting

A Phase 2 Clinical Trial to Evaluate Efficacy, Safety, and Tolerability of Navepegritide in Combination With Lonapegsomatropin in Children With Achondroplasia (COACH)

Achondroplasia

Denmark, Ireland, United Kingdom
Wuxi People's Hospital

Recruiting

The Clinical Efficacy and Safety of Intratumoral Injection of Chemotherapy for Advanced Solid Tumors

Cancer | Intratumoral Injection

China
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
Aldeyra Therapeutics, Inc.

Recruiting

A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

United States
AstraZeneca

Recruiting

MultIceNtre Non-intERVentional Study for Efficacy,Safety Evaluation of BREZTRI in Pts With COPD in RussiA (MINERVA)

Chronic Obstructive Pulmonary Disease

Russian Federation
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs

Unresectable Gallbladder Cancer

China
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
89bio, Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
Shanghai Changzheng Hospital

Not yet recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients

Advanced Hepatocellular Carcinoma
Biohaven Therapeutics Ltd.

Recruiting

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

Major Depressive Disorder

United States
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
AstraZeneca
Daiichi Sankyo

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung15)

Metastatic Non-small Cell Lung Cancer
Suzhou Kerui Medical Technology Co., Ltd
Suzhou Mingshi Optical Technology Co., Ltd

Recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression

Myopia

China
GlaxoSmithKline

Recruiting

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) (BE-EARLY)

Systemic Lupus Erythematosus

United States, Brazil, Mexico, Portugal, Spain, Argentina, France, Germany, Greece, Italy, Japan
MoonLake Immunotherapeutics AG

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
MoonLake Immunotherapeutics AG

Recruiting

Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Beijing Chest Hospital
The First Affiliated Hospital with Nanjing Medical University; Anhui Chest... and other collaborators

Recruiting

Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis

Tuberculosis | Treatment | Adjuvant

China
Famy Life Sciences, a Viatris Company

Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of Pimecrolimus 0.3% Ophthalmic Ointment

Blepharitis

United States
Sinotau Pharmaceutical Group

Not yet recruiting

A Clinical Study to Evaluate the Safety and Efficacy of Lutetium[177Lu] Oxodotreotide Injection in Patients With Advanced Neuroendocrine Neoplasms

Advanced Neuroendocrine Neoplasm

China
The Children's Hospital of Zhejiang University...
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
MediLink Therapeutics (Suzhou) Co., Ltd.

Not yet recruiting

A Phase 1 Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Advanced Solid Tumors

Advanced Solid Tumors

China
Fudan University

Recruiting

clinIcal Efficacy and Safety of Incadronate in Breast Cancer With Bone Metastases

Breast Cancer | Bone Metastases

China
Sinclair Pharmaceuticals Limited

Not yet recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of LANLUMA V to Improve Jawline Contour Deficit

Jawline Contour Deficit

China
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery

Anesthesia

China
Health Science Center of Xi'an Jiaotong University
Huazhong University of Science and Technology; LinkDoc Technology (Beijing)...

Not yet recruiting

Clinical Study of Huaier Granule in the Treatment of Unresectable Pancreatic Cancer

Pancreatic Cancer Non-resectable
Belite Bio, Inc

Not yet recruiting

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease (DRAGON II)

Stargardt Disease 1 | STGD1

United States
Beam Therapeutics Inc.

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha 1-Antitrypsin Deficiency

United Kingdom
Aldeyra Therapeutics, Inc.

Recruiting

A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

Canada
Suzhou Kerui Medical Technology Co., Ltd
2020 (Beijing) Medical Technology Co., Ltd

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Efficacy of Single-use Fibrous Ring Sutures for the Suture of Fibrous Ring Incision After Nucleus Pulposus Removal

Intervertebral Disc Disorder
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
MediLink Therapeutics (Suzhou) Co., Ltd.
Hoffmann-La Roche

Recruiting

A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
AQTIS Medical B.V.

Not yet recruiting

A Prospective, Randomized, No-treatment Controlled, Evaluator-blinded Clinical Trial to Evaluate the Efficacy and Safety of Polycaprolactone Microspherical Injectable to Improve Forehead Contour

Forehead Contouring

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism

Primary Aldosteronism | Mineralocorticoid Receptor Antagonist | Finerenone

China
Bio-Thera Solutions

Not yet recruiting

An Evaluation of BAT 8010 for Injection in Combination With BAT 1006 in Locally Advanced or Metastatic Entities Safety, Tolerability, Pharmacokinetic Profile, and Initial Clinical Efficacy of the Tumor in Patients Multicenter, Open Phase Ib/IIa Clinical Study

Advanced Solid Tumors
Nanfang Hospital, Southern Medical University

Not yet recruiting

A Clinical Study on the Efficacy and Safety of ABCD in the Treatment of Patients With Invasive Fungal Disease

Invasive Fungal Disease
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
Eilean Therapeutics

Not yet recruiting

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia

AML With Gene Mutations

Australia
L&C Bio
PROMeDis

Recruiting

Clinical Study to Evaluate the Anti-adhesion Efficacy and Safety of MegaShield®-SP in Comparison With Guardix-SP Plus After Spine Surgery

Herniation, Disc

Korea, Republic of
Zhejiang Hanmai Pharmaceutical Technology Co.,...

Not yet recruiting

Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of YJ001 for Spray Use in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States
Allife Medical Science and Technology Co., Ltd.
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb Ischemia

Critical Limb Ischemia

China
Sun Jing

Not yet recruiting

A Clinical Study on the Efficacy and Safety of Paclitaxel Polymer Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Locally Advanced Esophageal Squamous Cell Carcinoma
Blokhin's Russian Cancer Research Center

Not yet recruiting

A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors (RFAdesmoid)

Desmoid Fibromatosis | Desmoid Tumor | Desmoid

Russian Federation

3

Subscribe