Search clinical trials for: extravascular hemolysis

Total 293 results

Alexion Pharmaceuticals, Inc.

Active, not recruiting

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

Paroxysmal Nocturnal Hemoglobinuria

France, Italy, Spain, United States, Thailand, Korea, Republic of, United Kingdom, Israel, Czechia, Greece, Poland, Brazil, Japan, Canada, Malaysia
Alexion Pharmaceuticals, Inc.

Completed

Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)

Paroxysmal Nocturnal Hemoglobinuria

France, Italy, Spain, United States, Taiwan, Thailand, Korea, Republic of, Japan, Malaysia, Brazil, Germany, Israel, Czechia, Netherlands, Greece, United Kingdom, Canada, Poland
Alexion Pharmaceuticals, Inc.

Available

Danicopan Early Access Program

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
Alexion

Active, not recruiting

Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as Monotherapy

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, Italy, Canada, Korea, Republic of, New Zealand, Spain, Turkey
Apellis Pharmaceuticals, Inc.

Completed

Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects. (PADDOCK)

Paroxysmal Nocturnal Hemoglobinuria

Hong Kong, Thailand, New Zealand, Malaysia
Apellis Pharmaceuticals, Inc.

Completed

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States
Apellis Pharmaceuticals, Inc.

Completed

A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNH

PNH

Serbia, Bulgaria
Affiliated Hospital of Nantong University

Recruiting

Vivifrail Program on the Degree of Debilitation in Hospitalized Patients After Venous Hemolysis in Acute Ischemic Stroke

Ischemic Stroke | Frailty | Exercise Therapy

China
Inmunova S.A.
Chemo Research; KLIXAR; Linical; Crovelis

Not yet recruiting

Efficacy of INM004 in Children With STEC-HUS

Hemolytic-Uremic Syndrome

Argentina
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

Thrombocytopenia | Surgery | Acute Kidney Injury | Hemolysis

United States
Guangzhou Women and Children's Medical Center

Recruiting

Prediction and Evaluation by ETCOc of Neonatal Hyperbilirubinemia Cohort (PREVENT)

Neonatal Hyperbilirubinemia | Neonatal Jaundice | Hemolysis Neonatal

China
Mayo Clinic

Recruiting

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Preeclampsia

United States
McMaster University
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate

Renal Failure | Hemolysis
Institute of Hematology & Blood Diseases Hospital...
Juventas Cell Therapy Ltd.

Recruiting

CNCT19 for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.

Autoimmune Hemolytic Anemia | Autologous CD19 CAR-T | Failure of Three or More Lines of Therapy

China
Ahram Canadian University

Recruiting

Biodex Training in Hemodialysis Females With Osteopenia

Hemolysis

Egypt
Assiut University

Not yet recruiting

Detection of the Effect of Irrigation Fluid on Extravascular Lung Water in Patients Undergoing TRUP Using Bedside Lung Ultrasound

Anesthesia | TUR Syndrome
Institute of Hematology & Blood Diseases Hospital...
Suzhou Fundamenta Therapeutics

Recruiting

CAR-T for Autoimmune Hemolytic Anemia Patients Who Have Failed Three or More Lines of Therapy

Autoimmune Hemolytic Anemia | CD19 CAR-T Cell Infusion

China
Charles University, Czech Republic

Not yet recruiting

Renal Function and Hemolysis After Pulsed-field Ablation for Atrial Fibrillation

Atrial Fibrillation

Czechia
Assiut University

Not yet recruiting

Ultrasound Assessment of Extravascular Lung Water in Patients Undergoing Percutaneous Nephrolithotomy

Percutaneous Nephrolithotomy | Extravascular Lung Water
AstraZeneca

Recruiting

A Prospective, Non-interventional, Observational Study of Presentation, Treatment Patterns and Outcomes in Atypical Hemolytic Uremic Syndrome Patients

Atypical Hemolytic Uremic Syndrome(aHUS)

China
Charles University, Czech Republic

Not yet recruiting

Hemolysis During Pulsed-field and Radiofrequency Ablation

Atrial Fibrillation | Hemolysis | Pulsed-field Ablation

Czechia
Kasr El Aini Hospital

Not yet recruiting

B-lines Score as Indicator for the Systemic Volumetric Load During TURP

Transurethral Resection of Prostate

Egypt
Institute of Hematology & Blood Diseases Hospital...

Recruiting

The Safety and Efficacy of Zanubrutinib in Refractory/Relapsed Autoimmune Hemolytic Anemia

Refractory/Relapsed Autoimmune Hemolytic Anemia

China
Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Post-market Clinical Monitoring of the Safety and Efficacy of the Aortic Valve Bioprothesis (TiAra)

Aortic Valve Disease | Artificial Heart Valves

Russian Federation
University Hospital, Tours

Recruiting

French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy" (MATRIX)

Kidney Diseases | Hemolytic Uremic Syndrome | Acute Kidney Injury | Thrombotic Microangiopathy | Nephrology

France
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Atypical Hemolytic Uremic Syndrome

Japan, Turkey
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia (AIHA ITP CIN)

Myelodysplastic Syndromes | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Cold Agglutinin Disease | Autoimmune Neutropenia | Chronic Idiopathic Neutropenia

Italy
Peking Union Medical College Hospital

Recruiting

Sirolimus in the Treatment of Refractory/Relapsed wAIHA

Warm Autoimmune Hemolytic Anemia

China
Chen Miao

Recruiting

Zanubrutinib in the Treatment of Relapsed/Refractory wAIHA

Warm Autoimmune Hemolytic Anemia

China
Janssen Research & Development, LLC

Recruiting

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN) (AZALEA)

Hemolytic Disease of the Fetus and Newborn

Israel, Japan, Australia, United States, United Kingdom, Brazil
Alexion Pharmaceuticals, Inc.
AstraZeneca

Recruiting

Eculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in China (Soliris)

Atypical Hemolytic Uremic

China
Women's Hospital School Of Medicine Zhejiang University

Not yet recruiting

Clinical Value of ETCOc in the Diagnosis and Treatment of ABO-HDN

ABO Hemolytic Disease of Newborn
Mario Negri Institute for Pharmacological Research

Recruiting

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy (aHUS-iPSC-EC)

Atypical Hemolytic Uremic Syndrome

Italy
Novartis Pharmaceuticals

Not yet recruiting

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Atypical Hemolytic Uremic Syndrome
Zenas BioPharma (USA), LLC

Recruiting

A Study of Obexelimab in Patients With Warm Autoimmune Hemolytic Anemia (SApHiAre)

Warm Autoimmune Hemolytic Anemia

Japan, United States, Taiwan, Spain, Italy, United Kingdom, Turkey, Poland
Alpine Immune Sciences, Inc.

Recruiting

An Open-label Study of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)

Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Cold Agglutinin Disease | Warm Autoimmune Hemolytic Anemia

United States, Canada, Australia, Turkey, United Kingdom
Anthea Hospital Bari

Not yet recruiting

Electric Polarization of Red Blood Cells : A Cohort Study to Assess the Erythrocytes Membrane Integrity Through Charge Conservation, Following Cardiac Surgery. (Polaris)

Inflammatory Response | Hemolysis | Cardiovascular Disorder | Red Blood Cell Disorder | Erythrocyte Destruction

Italy
Assistance Publique - Hôpitaux de Paris

Recruiting

Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome (HYPERSHU)

Hypertensive Emergency-associated Hemolytic Uremic Syndrome

France
Assiut University

Not yet recruiting

Presence of Circulating Cluster of Differentiation 4 Positive 28 Null T Helper Lymphocytes(CD4+CD28-) in Patients With Autoimmune Hemolytic Anemia.

Autoimmune Hemolytic Anemia
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Ibrutinib for the Treatment of AIHA in Patients With CLL/SLL or CLL-like MBL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Autoimmune Hemolytic Anemia | Monoclonal B-Cell Lymphocytosis CLL-Type

Italy
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy

aHUS - Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals

Recruiting

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia (VAYHIA)

Warm Autoimmune Hemolytic Anemia (wAIHA)

China, Japan, Spain, Singapore, France, Germany, Taiwan, United States, Italy, India, Malaysia, Argentina, Hungary, Israel, Australia, Thailand, United Kingdom, Romania
Amsterdam UMC, location VUmc

Not yet recruiting

Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardiopulmonary Bypass, Part II (PRIME part II)

Hemolysis | Endothelial Dysfunction | Fluid Overload

Netherlands
Amsterdam UMC, location VUmc

Recruiting

Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardiopulmonary Bypass, Part I (PRIME part I)

Hemolysis | Endothelial Dysfunction | Fluid Overload

Netherlands
AtaCor Medical, Inc.

Recruiting

Subcostal Temporary Extravascular Pacing V Study (STEP V)

Conduction Defect

Paraguay
Assiut University

Not yet recruiting

Neonatal Cord Blood Screening for HDN

HDN - Hemolytic Disease of the Newborn
AtaCor Medical, Inc.

Recruiting

Pilot evaluatIon Of NovEl tEmpoRary ExtraVascular PACING (PIONEER EV PACING) Study

Conduction Defect

Croatia, Czechia
CARE Pharma Shanghai Ltd.

Recruiting

A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNH

Hemolysis | PNH

China
Ottawa Hospital Research Institute

Recruiting

Causes and Mechanisms of Space Hemolysis at High Altitudes (ANEMIA)

Anemia | Weightlessness

Canada
China National Biotec Group Company Limited
Xiangya Hospital of Central South University; Beijing Institute of Biological... and other collaborators

Recruiting

Immunogenicity and Safety of BBIBP-Corv Coadministered With PPV23 and IIV4 in Hemodialysis Population

COVID-19 | Hemolysis

China

Search clinical trials for: extravascular hemolysis

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