Search clinical trials for: first-line treatment failure

Total 75614 results

Institute of Tropical Medicine, Belgium
Damien Foundation

Active, not recruiting

Novel Triple-dose Tuberculosis Retreatment Regimen (Tri-Do-Re)

Tuberculosis | Pulmonary Tuberculosis | Multidrug-resistant Tuberculosis | Resistance to Tuberculostatic Drugs

Niger
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study.

Osteosarcoma, Advanced

China
University of Göttingen

Not yet recruiting

Retrospective Database Study: Survival of Cast Restorations - Restorations Made of Precious Metal vs. Non-precious Metal

Dental Restoration Failure
Nanfang Hospital, Southern Medical University

Not yet recruiting

PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive Stage
University of Sao Paulo General Hospital
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Not yet recruiting

Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

Heart Failure | Heart Transplant

Brazil
Fudan University

Recruiting

Clinical Study of T3011 Intravesical Instillation for Treatment of NMIBC Patients

Bladder Cancer

China
Peking Union Medical College Hospital

Not yet recruiting

A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag

Aplastic Anemia

China
Peking Union Medical College Hospital

Not yet recruiting

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

Aplastic Anemia

China
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
XIANG YANQUN

Not yet recruiting

Irinotecan Liposomes in Combination With Nituzumab for the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of First-Line or Higher Immunotherapy

Nasopharyngeal Cancer

China
Tianjin Medical University Cancer Institute and...

Recruiting

Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure

HCC

China
University of Zurich
Swiss HIV Cohort Study

Recruiting

Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures

HIV Infections

Switzerland
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure

Heart Failure | Decompensated Heart Failure
Yehua Shen

Not yet recruiting

HAIC Combined With PD-L1 Plus Regorafenib in the Treatment of Advanced Hepatocellular Carcinoma After Immunotherapy Failure

HCC - Hepatocellular Carcinoma
Medical University of Warsaw

Not yet recruiting

Polish Nationwide Register of Hospitalized Patients in Cardiac Intensive Care Units (POL-CICU)

Stroke | Infections | Shock | Death | Multiple Organ Failure | Treatment Complication | Cardiac Intensive Care Unit
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Fecal Microbiota Transplantation by Oral Capsules for Hepatic Encephalopathy Treatment

Hepatic Encephalopathy | Dysbiosis

Italy
Reprieve Cardiovascular, Inc

Not yet recruiting

EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System (FASTR-EU) (FASTR-EU)

Acute Decompensated Heart Failure

Netherlands, Poland
Fresenius Medical Care Deutschland GmbH

Not yet recruiting

Comparison of Individualized Sodium Management Versus Standard Treatment in Hemodialysis (SODIAH)

End Stage Renal Disease
Academisch Ziekenhuis Maastricht
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Timely Recovery After Subclinical Heart Failure (TREASURE)

Heart Failure | Diastolic Dysfunction

Netherlands
Inonu University

Not yet recruiting

Treatment According to Venous Excess Ultrasound Score in Patients With Heart Failure

Heart Failure | Acute Kidney Injury
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma

Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

China
Pr. Nicolas GIRERD

Recruiting

PAtient Treatment Analysis: Hospital and Wide-ranging Out-of-hospital Care Assessment Yields Insights Into Heart Failure Outcomes (PATHWAY-HF)

Heart Failure

France
Henan Cancer Hospital

Recruiting

Serplulimab Plus Bevacizumab and Chemotherapy for EGFR-mutant Metastatic NSCLC Patients After EGFR-TKI Treatment Failure

Non-Squamous Non-Small Cell Lung Cancer

China
European Institute of Oncology

Recruiting

Total Body Irradiation Treatments for Patients Treated at European Institute of Oncology

Lymphoma | Leukemia | Aplastic Anemia | Leukemia, Acute | Leukemia, Chronic

Italy
Hunan Cancer Hospital

Not yet recruiting

Cadonilimab in Combination With Anlotinib in the Treatment of Locally Progressive or Metastatic Melanoma With First-Line Therapy Failure

Melanoma
I.M. Sechenov First Moscow State Medical University

Recruiting

ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction (BOT-IMPROVE-HF)

Chronic Heart Failure With Low Ejection Fraction

Russian Federation
abdulmajeed hammadi

Recruiting

Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells (alfarah)

Premature Ovarian Insufficiency

Iraq
Miromatrix Medical Inc.

Not yet recruiting

miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial

Acute Liver Failure | Acute Liver Injury, Drug Induced

United States
Complejo Hospitalario Universitario de Albacete

Recruiting

Calcifediol in the Treatment of SARS-CoV-2 Disease (COVID-19). (COVIDIOL)

SARS-CoV 2 Pneumonia

Spain
Institute of Liver and Biliary Sciences, India

Not yet recruiting

An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response

Acute on Chronic Liver Failure

India
Novo Nordisk A/S

Recruiting

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

United States, Netherlands, Germany, Canada, Czechia, France, Italy, Portugal, Spain
Aalborg University Hospital
Bispebjerg Hospital; Viborg Regional Hospital

Not yet recruiting

Treatment of Acute Hypercapnic Respiratory Failure With OptiflowTM or Optiflow+DuetTM Nasal Cannula in COPD-patients (DUACT)

COPD | Hypercapnic Respiratory Failure
Institute of Hematology & Blood Diseases Hospital...
Fosun Pharmaceutical Distribution Jiangsu co., Limited

Not yet recruiting

Efficacy and Safety of Avatrombopag vs. Avatrombopag Combined With rhTPO in the Treatment of SAA

Anemia, Aplastic
Mina sobhi said fam

Recruiting

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

Stellate Ganglion Block

Egypt
Fresenius Medical Care Deutschland GmbH
Metronomia Clinical Research GMBH

Not yet recruiting

Retrospective Data Analysis of CKRT (Continuous Kidney Replacement Therapy) Treatments in Adult Mode With multiFiltratePRO (CKRT-AKI)

Renal Failure | Acute Kidney Injury
Swedish Orphan Biovitrum

Recruiting

A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients

Hereditary Tyrosinemia, Type I

China
Heart Center Research, LLC
Boston Scientific Corporation

Recruiting

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts (DART-HA)

Heart Failure, Congestive

United States
Sichuan University

Not yet recruiting

HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis

Gastric Cancer | Peritoneal Metastases
Harbin Medical University

Not yet recruiting

AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer

Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma
Sichuan University

Recruiting

Sunvozertinib Combined With Chemotherapy for EGFRm After EGFR-TKI Treatment Failure：Phase I/II (WU-KONG36)

Non Small Cell Lung Cancer

China
AstraZeneca

Recruiting

A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece (SHIELD)

Hyperkalaemia

Greece
University of Aarhus
Central Denmark Region

Recruiting

Strategy for Prompt and Effective Thoracentesis in the Emergency Department (SPEEDTAP)

Heart Failure | Pleural Diseases | Pleural Effusion

Denmark
China-Japan Friendship Hospital

Recruiting

Safety and Efficacy of Radiotherapy Combined With Immunotherapy for Advanced Malignant Tumors.

Advanced Solid Tumor

China
University Hospital, Strasbourg, France

Recruiting

Study of Predictors of Failure of Sulprostone Treatment in Postpartum Hemorrhage (NALAPOST)

Postpartum Hemorrhage

France
Niguarda Hospital
Mario Negri Institute for Pharmacological Research; Ministry of Health, Italy; European Union and other collaborators

Recruiting

CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine (CMP-MYTHiC)

Heart Failure | Myocarditis | Cardiomyopathies | Ventricular Arrythmia | Inflammatory Cardiomyopathy

Italy
Qianfoshan Hospital

Not yet recruiting

Real-world Research : Assessment of Effect of Combination of Drugs in the Treatment of Heart Failure

Heart Failure
University of Leipzig

Recruiting

Cardiac Amyloidosis Registry of University Hospital Leipzig

Cardiac Amyloidosis

Germany
Herlev and Gentofte Hospital
Zealand University Hospital; University Hospital Bispebjerg and Frederiksberg; Copenhagen University Hospital, Hvidovre and other collaborators

Not yet recruiting

Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy (WEAN-HF)

Heart Failure With Reduced Ejection Fraction | Heart Rhythm Disorder
Novo Nordisk A/S
Duke Clinical Research Institute

Not yet recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack (ARTEMIS)

Cardiovascular Risk | Acute Myocardial Infarction (AMI)

Canada, China, United States, Germany, Spain, Korea, Republic of, Netherlands, Australia, Italy, Denmark, India, United Kingdom, Argentina, Turkey, Mexico, Malaysia, Czechia, Poland, Brazil, France, Japan, Bulgaria, Greece, Israel

Search clinical trials for: first-line treatment failure

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