Search clinical trials for: gene polymorphisms

Total 268908 results

Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
October 6 University
University of Florida; Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients

Heart Failure | Genetic Polymorphisms

United States
Marmara University

Not yet recruiting

Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization

Molar-Incisor Hypomineralization
LI YAN

Not yet recruiting

Study on the Association of GSTP1 and Other Gene Polymorphisms With Platinum-induced Myelosuppression

Non-small Cell Lung Cancer
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina
Lebanese University
Haykel Hospital

Recruiting

Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms (CAT_PB)

Cardiovascular Diseases | Immune System Diseases | Cancer | Breast Cancer | Hepatocellular Carcinoma | Lung Cancer | Chemotherapy | Solid Tumor | Prostate Cancer | Thromboembolism | Colon Cancer | Immunotherapy | Inflammatory Diseases

Lebanon
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-Small Cell Lung Cancer

United States
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Alectinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-small Cell Lung Cancer

United States
Mazandaran University of Medical Sciences

Recruiting

Baricitinib Versus Azathioprine in Patients With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

Iran, Islamic Republic of
Hospital Mutua de Terrassa

Recruiting

Mesenteric Bacterial Translocation in Evolved Crohn's Disease (MESENCROHN)

Crohn Disease

Spain
IRCCS Burlo Garofolo

Recruiting

Genetic Polymorphisms in Drug Induced Neuropathy in Children With ALL

Acute Lymphocytic Leukemia

Italy
Aristotle University Of Thessaloniki

Not yet recruiting

Peri-implantitis and MMP-8

Peri-Implantitis
Bangabandhu Sheikh Mujib Medical University, Dhaka...
Department of Genetic Engineering and Biotechnology, Dhaka University

Recruiting

Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS

Polycystic Ovary Syndrome | Metformin

Bangladesh
Poznan University of Life Sciences

Recruiting

Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance

Skeletal Muscle Performance | Gene Polymorphisms

Poland
Sohag University

Recruiting

Expression of IRAK1 Gene rs1059703-related Single- Nucleotide Polymorphisms in Egyptian Patient With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)

Egypt
Assiut University

Not yet recruiting

Relation of IL23R and IL17A Gene Polymorphisms Plus Serum Levels of IL23 and IL17A to Rheumatoid Arthritis Susceptibility and Activity

Rheumatoid Arthritis
Maastricht University Medical Center

Recruiting

PCSK9 Polymorphism and Risk of Cardiac Rupture

Post-Infarction Heart Rupture | Gene Polymorphism

Italy
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (PALOMA-2)

Carcinoma, Non-small-Cell Lung

United States, Korea, Republic of, Italy, Israel, Malaysia, United Kingdom, China, Brazil, Spain, Germany, Japan, France
Sohag University

Not yet recruiting

The Expression of Immune Checkpoint CD28 rs1980422-related Single-nucleotide Polymorphisms in the Primary Immune Thrombocytopenia

Immune Thrombocytopenia

Egypt
Sohag University

Recruiting

Assessment of FOXP3 Gene Polymorphisms and Serum Interleukin 10 in Patients With ITP (FoxP3ITP)

Thrombocytopenia

Egypt
Wake Forest University Health Sciences
Atrium Health Levine Cancer Institute

Recruiting

Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma

Cachexia | Pancreas Adenocarcinoma

United States
Hospices Civils de Lyon

Not yet recruiting

The Aim is to Identify Recurrent Genomic Mutations and/or Predisposing Polymorphisms in Patients With Sporadic Cases of Multiple Myeloma (MMSPORADGEN)

Multiple Myeloma

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sun Yat-sen University

Recruiting

Study on Umorestat Hydrogen Sulfate Capsule in Patients With Locally Advanced/Metastatic Pancreatic Cancer

Pancreatic Cancer | Pharmacokinetics | Gene Polymorphisms

China
Ain Shams University

Not yet recruiting

Effect of Genetic Polymorphisms of UGT on the PKs of Indapamide in Egyptians (UGT/PKs)

Pharmacogenomics
Ain Shams University

Not yet recruiting

Evaluation of the Effect of Genetic Polymorphisms in ERCC1 and OCT2 on the Occurrence and Severity of Cisplatin-induced Nephrotoxicity

Cisplatin Adverse Reaction

Egypt
Leonardo Paroche de Matos
Prof. Dr. José Antônio Silva Júnior; Msc. Allan Luis Barboza Atum

Not yet recruiting

Impact of Genetic Polymorphisms of Vasoactive Peptides on the Prognosis of Patients With COVID19

Sars-CoV-2 Infection

Brazil
Affiliated Hospital of Qinghai University

Recruiting

Genetic Predictors to Acupuncture Response for Arthralgia Induced by Aromatase Inhibitors in Patients With Breast Cancer

Breast Cancer

China
Affiliated Hospital of Qinghai University

Recruiting

Genetic Predictors of Response to Acupuncture for Cancer-related Fatigue Among Breast Cancer Patients After Chemotherapy

Breast Cancer

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM

Type 2 Diabetes Mellitus

China
University Hospital, Toulouse

Recruiting

Identification of New Biomarkers for the Prediction of Cardiovascular Events (CDPA-Biobank)

Cardiovascular Diseases

France
Egas Moniz - Cooperativa de Ensino Superior, CRL
Oral Reconstruction Foudation

Recruiting

Analysis of Genetic Variations in Patients With Peri-implantitis

Peri-Implantitis

Portugal
University of Florida

Recruiting

Treatment of Pruritus With Intramuscular Promethazine

Pregnancy Related | Pruritus

United States
Croatian Science Foundation

Recruiting

Genetic Polymorphisms and Their Association With Temporomandibular Disorders (GenPolTMD)

Temporomandibular Disorders | Orofacial Pain

Croatia
Manchester University NHS Foundation Trust
University of Nottingham; University of Manchester; Innovate UK

Recruiting

Integrated Diagnostics for Early Diagnosis of Liver Disease (ID LIVER)

Alcoholic Liver Disease | Non-Alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis | Liver Fibroses

United Kingdom
Centre Hospitalier Universitaire de Nīmes
Universidad Autonoma de Madrid

Recruiting

Effect of Genetic Alterations in Key Genes in the Kynurenine Pathway on Suicidal Behavior (SuiKYN)

Suicidal Behavior | Polymorphism | Kynureninase

France, Spain
University of Exeter

Recruiting

Aquaporin-4 Single Nucleotide Polymorphisms in Patients With Idiopathic and Familial Parkinson's Disease

Parkinson Disease

United Kingdom
Fondazione Don Carlo Gnocchi Onlus

Recruiting

Predictors of Better Outcomes After Severe Acquired Brain Injuries (FP-GCA)

Brain Injuries | Disorder of Consciousness

Italy
University of Leipzig

Recruiting

Leipzig Childhood Obesity Study

Childhood Obesity

Germany
Second Affiliated Hospital, School of Medicine,...
Zhejiang Provincial Hospital of TCM; Guiyang Hospital of Stomatology

Recruiting

Head Yuanshi Dian Therapy in Burning Mouth Syndrome

Burning Mouth Syndrome | Oral Mucosa Disease

China
Aristotle University Of Thessaloniki

Recruiting

Association of Single Nucleotide Polymorphisms (SNPs) in Metalloproteinases (MMPs) Genes With the Risk of Primary Knee Osteoarthritis in Greek Population.

Metalloproteinase SNPs -1575 G/A MMP-2, 836 A/G MMP-9 and -77 A/G MMP-13 and Risk for Developing Knee Osteoarthritis in Greek Population

Greece
Alexandra Hospital, Athens, Greece

Recruiting

Genetic Polymorphisms of ABCB11 and ABCB4 in Women With Intrahepatic Cholestasis of Pregnancy (ICP) and in Their First Degree Relatives

Cholestasis of Pregnancy

Greece
University Hospital, Geneva
Jules Desmeules; Youssef Daali; Kenza Abouir; Eduardo Schiffer; Bernard Walder

Recruiting

Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol (PREDICT)

Pain | Interaction

Switzerland
Neuromed IRCCS

Recruiting

Role of ADA SNPs in Subjects With Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis

Italy
Janssen Research & Development, LLC

Recruiting

A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer (Chrysalis-2)

Carcinoma, Non-Small-Cell Lung

Taiwan, United States, Korea, Republic of, Germany, France, China, Japan, Italy, Spain, Puerto Rico
Neuromed IRCCS

Recruiting

miR-142-3p as Potential Biomarker of Synaptopathy in MS

Multiple Sclerosis | Spasticity

Italy

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