Search clinical trials for: kappa-opioid receptors

Total 475 results

BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Jules Bordet Institute
RayzeBio, Inc.

Not yet recruiting

A Phase I Study to Assess the Tolerability of 225Ac-DOTATATE in Patients With Refractory and Relapsing Multiple Myeloma Expressing Somatostatin Receptors (AcTRESS)

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Multiple Myeloma Progression

Belgium
National Cancer Institute (NCI)

Not yet recruiting

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Carcinoma, Neuroendocrine | Tumor, Neuroendocrine | Tumors, Neuroendocrine | Neuroendocrine; Carcinoma | Small Cell; Receptors

United States
University Hospital, Geneva

Not yet recruiting

Investigation of the Evolution of Gastric Emptying by Gastric Ultra Sonography in Patients Treated With GLP-1 Receptor Agonists on a 7 Days Pausing Period.

Diabetes Mellitus, Type 2 | Anesthesia | Pulmonary Aspiration of Gastric Contents
Universitaire Ziekenhuizen KU Leuven
Eli Lilly and Company; Kom Op Tegen Kanker; Teva Pharma

Recruiting

Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer (ABBICAR)

Triple Negative Breast Neoplasms

Belgium
National Cancer Institute (NCI)

Not yet recruiting

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Chronic Lymphocytic Leukemia (CLL)

Leukemia, Lymphocytic, Chronic, B-Cell | B-Cell Chronic Lymphocytic Leukemia | B-Lymphocytic Leukemia, Chronic

United States
Assiut University

Recruiting

Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury

Treatment of Posttraumatic Cognitive Dysfunction

Egypt
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

The Role of Platelet TLRs in Platelet Activation During VTE (ROT-PLAT-VTE)

Venous Thromboembolism

France
National Cancer Institute (NCI)

Recruiting

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Gastrointestinal Cancer | Genitourinary Cancer | Metastatic Solid Cancers

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Estrogen Receptors and HER2 Levels' Expression in Luminal Metastatic Breast Cancer (CYCLHER)

Advanced Breast Carcinoma

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors (NETTUNO)

Postoperative Complications | Surgical Procedure, Unspecified | Hyperlactatemia | Abdomen Disease

Italy
Lakehead University

Recruiting

Over-the-Counter Antihistamines & Heat Stress

Allergic Rhinitis | Heat Illness | Heat Injury | Sudomotor Sympathetic Dysfunction

Canada
Anna Stanhewicz, PhD

Recruiting

Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia

Preeclampsia

United States
University Hospital, Strasbourg, France

Recruiting

Hematological Effects of Atypical Antipsychotics (AAPs) in a Geriatric Population: What is the Role of 5-HT2 Receptors (AAPs)

Neutropenia

France
Fred Hutchinson Cancer Center
Bristol-Myers Squibb

Not yet recruiting

Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer

Stage IV Prostate Cancer AJCC v8 | Prostate Carcinoma | Stage III Prostate Cancer AJCC v8 | Prostate Small Cell Neuroendocrine Carcinoma

United States
Cancer Research UK
Aleta BioTherapeutics

Recruiting

A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell

United Kingdom
Fred Hutchinson Cancer Center
Affini-T Therapeutics, Inc.

Recruiting

Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Pancreatic, Colorectal and Non-Small Cell Lung Cancers With KRAS G12V Mutations

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Metastatic Colorectal Adenocarcinoma | Stage IV Lung Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Fetal Cell Receptors Repertoire (MoreCCR)

Venous Ulcer | Diabetic Ulcer | Sickle Cell Ulcer | Post-partum Women | Mixed Ulcer

France
University of Alberta

Recruiting

Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences (STARS)

Vasodilation | Vasoconstriction

Canada
Pharmazz, Inc.

Recruiting

Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Cerebral Ischemia

India
Tomsk National Research Medical Center of the Russian...
Uppsala University

Recruiting

Molecular Imaging of Gastrin Releasing Peptide Receptors Using Labeled Technetium-99m DB8

Breast Cancer | Prostate Cancer

Russian Federation
Anna Stanhewicz, PhD

Recruiting

Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia

Preeclampsia Postpartum

United States
Assiut University

Not yet recruiting

Role of LILRA3 in Ankylosing Spondylitis and Axial Psoriatic Patients

Autoimmune Diseases
InCor Heart Institute

Recruiting

The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers (RE-AGES)

Coronary Artery Disease | Menopause | Endothelial Dysfunction

Brazil
Pharmazz, Inc.

Not yet recruiting

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Ischemic Stroke | Cerebral Stroke
Christian Hinrichs

Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical Cancer | HPV-Related Malignancy | Metastatic Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
China Medical University Hospital

Recruiting

The Roles of Human Microbiome and Vitamin D in the Development of Childhood Allergic Diseases

Pediatric

Taiwan
Centre Antoine Lacassagne

Recruiting

Study to Determine the Safety and Efficacy of Ribociclib in Combination With Hormone Therapy and Hypofractionated Radiotherapy in Breast Cancer, With Positive Hormone Receptors and Negative HER2 Status, in Newly Diagnosed, Not Immediately Operable Elderly Patient (CALHYS) (CALHYS)

HER2 Negative Breast Cancer Not Immediately Operated

France
Perspective Therapeutics

Recruiting

MC1R-targeted Alpha-particle Therapy Trial in Adults With Advanced Melanoma

Metastatic Melanoma | Melanoma (Skin) | Mucosal Melanoma | Melanoma Stage IV | Melanoma Stage III | Melanoma, Uveal

United States
Janssen Pharmaceutical K.K.

Recruiting

A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer (TAR-210)

Urinary Bladder Neoplasms | Receptors, Fibroblast Growth Factor

Japan
Cerevel Therapeutics, LLC

Recruiting

Positron Emission Tomography (PET) Trial to Evaluate Target Occupancy of CVL-354 at Kappa and Mu Opioid Receptors in Brain Following Oral Dosing

Opioid Use Disorder

United States
China Medical University Hospital

Recruiting

Vitamin D Treatment Effect for Atopic Dermatitis in Children

Atopic Dermatitis

Taiwan
China Medical University Hospital

Recruiting

The Association Between Human Microbiome and Vitamin D in Chronic Urticaria

Urticaria

Taiwan
Shanghai Unicar-Therapy Bio-medicine Technology...
The First Affiliated Hospital of Soochow University

Recruiting

CD19 Chimeric Antigen Receptors and CD19 Positive Feeder T Cells as a Leukemia Consolidation Treatment

Acute Lymphoblastic Leukemia in Remission

China
Innovative Cellular Therapeutics Inc.

Recruiting

GCC19CART for Patients With Metastatic Colorectal Cancer (CARAPIA-1)

Colorectal Cancer

United States
Janssen Research & Development, LLC

Recruiting

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

Urinary Bladder Neoplasms | Receptors, Fibroblast Growth Factor

Korea, Republic of, United States, Germany, Spain, Netherlands
Yale University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Systems Investigation of Vaccine Responses in Aging and Frailty

Influenza

United States
Cancer Research UK
Teon Therapeutics, Inc.

Recruiting

TT-702 in Patients With Advanced Solid Tumours. (CURATE)

Advanced Solid Tumors

United Kingdom
Instituto Mexicano del Seguro Social

Recruiting

Clinical Response to Magnesium Sulfate as an Adjunct in the Anesthesia

Anesthesia and Analgesia | Magnesium Sulfate

Mexico
Thomas Hummel

Recruiting

Bitter Taste Receptors in Oropharynx Cancer

Oropharynx Cancer

Germany
International Cancer Research Group, United Arab...
King Saud University Medical City, Riyadh, Saudi Arabia; Max-Planck-Institut... and other collaborators

Recruiting

Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies. (ICRG0201)

Hormonal Receptors Positive, HER2 Negative, Advanced Breast Cancer

Algeria, Jordan, Saudi Arabia
Central Hospital, Nancy, France

Not yet recruiting

Early Feasibility Study of Somatostatin Receptors PET Imaging for the Diagnosis of Infective Endocarditis (DOTENDO)

Infective Endocarditis
Assiut University

Not yet recruiting

Expression of Toll-like Receptors 3 , 7 and 9 in Peripheral Blood Mononuclear Cells of COVID-19 Patients

COVID-19 Respiratory Infection
LianBio LLC

Recruiting

Infigratinib in Subjects With GC or GEJ With FGFR2 Amplification or Other Solid Tumors With Other FGFR Alterations (FGFR)

Gastric Cancer | Solid Tumor | Gastroesophageal Junction Adenocarcinoma

China
Rajesh Narendran
National Institute on Drug Abuse (NIDA)

Recruiting

[C-11]NPA PET-amphetamine in Cocaine Use Disorders

Cocaine Use Disorder

United States
Rajesh Narendran
National Institute on Drug Abuse (NIDA)

Recruiting

Imaging CRF X NOP Interactions in CUD

Cocaine Use Disorder

United States
University Hospital, Basel, Switzerland
Swiss Cancer League

Recruiting

Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-satoreotide (PROMENADE)

Meningioma

Switzerland
Ardigen
National Center for Research and Development, Poland

Recruiting

Creating an Innovative AI-based Technology TCRact for Designing and Optimizing T-cell Receptors (TCR) for Use in Cancer Immunotherapies

Cancer | Colon Cancer

Poland
National Institute of Diabetes and Digestive and...

Recruiting

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

Metastic Thyroid Cancer

United States

Search clinical trials for: kappa-opioid receptors

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