Search clinical trials for: lipid lowering

Total 9728 results

Atlantic Health System
Regeneron Pharmaceuticals

Not yet recruiting

Atlantic Lipid Lowering Treatment Optimization Program (ALLTOP)

Familial Hypercholesterolemia | High Density Lipoprotein Deficiency | Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia | Apolipoprotein B 100, Familial Defective | Low-Density-Lipoid-Type Hyperlipoproteinemia

United States
Cedars-Sinai Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

Prostate Cancer
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Fondazione SISA (Societa Italiana per lo Studio...

Recruiting

Lipid Transport Disorder Italian Genetic Record (LIPIGEN) (LIPIGEN)

Familial Hypercholesterolemia | Genetic Disorder

Italy
Brigham and Women's Hospital
Esperion Therapeutics, Inc.

Recruiting

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy (PAD-ALERT)

Peripheral Vascular Diseases | Dyslipidemias | Peripheral Artery Disease

United States
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Yonsei University

Not yet recruiting

Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)

Peripheral Artery Disease | Polyvascular Disease

Korea, Republic of
Fu Wai Hospital, Beijing, China

Not yet recruiting

Anti-inflammatory Therapy for Recurrent In-stent Restenosis

In-stent Restenosis

China
First Affiliated Hospital of Wenzhou Medical University

Recruiting

The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy

China
Assiut University

Not yet recruiting

Telenursing Through Short Messaging Service: It's Effect on Lipid Lowering Medication Adherence Outcomes

Telenursing Lipid Lowering Medication Adherence
Queen's University, Belfast
Belfast Health and Social Care Trust

Recruiting

Determining the Lipid Lowering Effect of Fenugreek Seed Tea

Hyperlipidemias

United Kingdom
Imperial College London
Sanofi; Axtria, Inc.

Recruiting

OptimiZation Of Lipid Lowering Therapies Using a Decision Support System In Patients With Acute Coronary Syndrome. (ZODIAC)

Myocardial Infarction | Ischemic Stroke | Acute Coronary Syndrome

United Kingdom
Monash University
Novartis Pharmaceuticals

Recruiting

VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN) (v-ASCERTAIN)

Cerebrovascular Disease | Coronary Heart Disease (CHD) | Peripheral Arterial Disease (PAD) | Atherosclerotic Cardiovascular Disease (ASCVD)

Australia
Zibo Central Hospital

Recruiting

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Adverse Effect of Cardiovascular Medications (Diagnosis)

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Plaque Reversal With Early, Aggressive Lipid Lowering Therapy (EAGLE)

Coronary Artery Disease Progression

Netherlands
China National Center for Cardiovascular Diseases

Recruiting

LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)

Atherosclerotic Cardiovascular Disease | LDL Cholesterol | Older Patients

China
University Hospital, Basel, Switzerland
SolidarMed; Swiss Agency for Development and Cooperation (SDC); World Diabetes...

Recruiting

Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho (ComBaCaL T2D)

Type 2 Diabetes Mellitus (T2D)

Lesotho, Switzerland
Duke University

Recruiting

A Feasibility Trial of OCM Supplements for the Treatment of NAFLD

NAFLD

United States
Chinese University of Hong Kong
Gormin Tan gtan

Recruiting

Perceive and Calculated CV Risk

Patient-Perceived Versus

Hong Kong
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cholesterol Lowering and Residual Risk in Diabetes, Type 1 (CHORD1)

Type 1 Diabetes

United States
Samara Regional Cardiology Dispensary
Samara State Medical University

Recruiting

Effect of Combined Lipid-lowering Therapy on Atherosclerotic Plaque Vulnerability in Patients With ACS (Combi-LLT ACS)

Dyslipidemias

Russian Federation
Henan Institute of Cardiovascular Epidemiology

Recruiting

Effect of Very Early and Rapid Lowering Cholesterol With Evolocumab on Left Ventricular Remodeling in Patients With Anterior STEMI Undergoing Primary PCI (EVALUATE-STEMI)

ST Elevation Myocardial Infarction (STEMI)

China
Jena University Hospital

Not yet recruiting

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target) (GoT)

ST Elevation Myocardial Infarction | Non-ST Elevation Myocardial Infarction | LDL-cholesterol

Germany
Priscilla Hsue, MD
Massachusetts General Hospital; University of California, Los Angeles

Recruiting

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

Cardiovascular Diseases | HIV Infections | Atherosclerosis | Dyslipidemias

United States
Chinese Academy of Medical Sciences, Fuwai Hospital

Recruiting

Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population (ILLUMINATION)

Coronary Artery Disease Progression

China
Novartis Pharmaceuticals

Recruiting

Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD (VICTORION REAL)

Mixed Dyslipidemia | Primary Hypercholesterolemia

Switzerland, Saudi Arabia, United Arab Emirates, United Kingdom, Austria, Israel, China, Malaysia
Helsinki University Central Hospital
University of Helsinki

Recruiting

KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug (KF2019#1)

Pharmacokinetics

Finland
Third Military Medical University

Recruiting

Effect of Bariatric Surgery Versus Medical Therapy on Metabolic Syndrome (EBSMTMS)

Metabolic Syndrome

China
Novartis Pharmaceuticals

Recruiting

A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting

Hypercholesterolemia

Germany
Stephen Nicholls
Amgen

Recruiting

Guideline Oriented Approach To Lipid Lowering In Asia-Pacific (GOAL-ASIA)

Cardiovascular Diseases | Atherosclerosis | Hypercholesterolemia | Acute Coronary Syndrome

Thailand, Australia, Korea, Republic of, Japan, Malaysia, Singapore
Kaiser Permanente
Esperion Therapeutics, Inc.

Not yet recruiting

Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study

Cardiovascular Diseases | STEMI | NSTEMI

United States
University of California, San Francisco

Not yet recruiting

Methylglyoxal (MGO) Lowering Cocktail to Reduce Appetite in Obese Individuals

Obesity | Aging

United States
Radboud University Medical Center

Recruiting

Ultrasound Elastography for Individual Carotid Plaque Stratification (Ultra-COMPASS)

Carotid Artery Plaque

Netherlands
Penza State University

Recruiting

Evaluation of the Effect of Long-term Lipid-lowering Therapy in STEMI Patients With Coronavirus Infection COVID-19 (CONTRAST-3)

Covid19 | STEMI | NSTEMI

Russian Federation
Bjarne Linde Noergaard

Recruiting

Influence of Intensive Lipid-lowering on FFRCT (The FLOW-PROMOTE Study) (FlowPromote)

Coronary Artery Disease

Denmark
Azienda Ospedaliera Ordine Mauriziano di Torino

Recruiting

CARotid plaqUe StabilizatiOn and Regression With Evolocumab. (CARUSO)

Carotid Artery Disease

Italy
Korea University Anam Hospital

Recruiting

Impact of Evolocumab as an Additional Lipid-lowering Therapy to Changes in Lipid Core Burden Index of Non-culprit Vulnerable Plaque in Patients Who Underwent Percutaneous Coronary Intervention for the Acute Coronary Syndrome

Acute Coronary Syndrome | Clinical Trial

Korea, Republic of
Penza State University

Recruiting

Assessment of the Effects of Long-term Lipid-lowering Therapy in Patients With Primary STEMI or NSTEMI (CONTRAST-2)

Quality of Life | Arterial Stiffness | Myocardial Infarction, Acute | Myocardial Strain

Russian Federation
Duke University
National Heart, Lung, and Blood Institute (NHLBI); National Institute on Aging... and other collaborators

Recruiting

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults (PREVENTABLE)

Cardiovascular Diseases | Dementia | Cognitive Impairment, Mild

United States, Puerto Rico
Tianjin Chest Hospital

Recruiting

Effect of Evolocumab Added to Moderate-Intensity Statin Therapy on LDL-C Lowering and Cardiovascular Adverse Events in Patients With Acute Coronary Syndrome (EMSIACS)

Acute Coronary Syndrome | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor

China
University of Cambridge
Lund University; GE Healthcare; Cambridge University Hospitals NHS Foundation... and other collaborators

Recruiting

PET Imaging of Inflammation and Lipid Lowering Study (PIILL)

Atherosclerosis | Carotid Artery Plaque | Hypercholesterolemia | Hypercholesterolemia, Familial

United Kingdom
Tampere University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Recruiting

Impact of Atorvastatin on Prostate Cancer Progression During ADT (ESTO2)

Recurrent Prostate Cancer | Metastatic Prostate Cancer

Finland, Norway, Estonia, Denmark
University Hospital, Montpellier
University Hospital, Toulouse

Recruiting

Assessment of Compliance With European and French Guidelines for the Management of Dyslipidaemias (OBDYSLIP)

Patient With Dyslipidemia

France
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Completed

Evaluating the Efficacy of AI-Guided vs. Standard Physician-Guided Dietary Supplement Prescriptions for Lowering LDL Cholesterol in Hypercholesterolemic Patients

Hypercholesterolemia

Russian Federation
Amgen

Completed

Chart Review of Repatha® in Subjects With Hyperlipidaemia (HEYMANS)

Hypercholesterolaemia

Austria, Italy, Belgium, Czechia, Switzerland, Spain, Slovakia, Germany, Portugal, Greece, Bulgaria, Sweden
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia (V-DIFFERENCE)

Hypercholesterolemia

Germany, Estonia, Spain, France, Bulgaria, Latvia, Poland, Czechia
Amgen

Completed

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER)

Dyslipidemia

United States, Austria, Belgium, Canada, Denmark, Finland, France, Germany, Italy, Netherlands, Spain, Sweden, United Kingdom, Czechia, Hungary, Taiwan, Colombia, Poland, Russian Federation, Switzerland, Korea, Republic of, Mexico, ... and more
Jubilee Mission Medical College and Research Institute
Christian Medical College, Vellore, India

Active, not recruiting

Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians (CLIP)

Hypertension | BMI | Cholesterol, Elevated | Lifestyle Risk Reduction | LDL Hyperlipoproteinemia | HbA1C | Lipoprotein(A)

India
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Germany, Hungary, Colombia, Mexico

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