Search clinical trials for: multiple ascending dose healthy volunteers

Total 55921 results

Celgene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity

Healthy Participants

United States
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia
BeiGene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035

Autoimmune Diseases | Healthy Volunteers | Healthy Subjects | Healthy Participants | Healthy Adult Participants
Foresee Pharmaceuticals Co., Ltd.
InClin, Inc.

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers

Healthy

Australia
Almirall, S.A.

Recruiting

A Single and Multiple Ascending Dose Study of LAD603 in Healthy Subjects

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Safety Study of SLV213 for the Treatment of COVID-19.

COVID-19

United States
Acesion Pharma

Recruiting

Single Ascending Dose, Multiple Ascending Dose, Food Effect Study With AP31969

Healthy Volunteers

Netherlands
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers

Bladder Cancer

Australia
Arxx Therapeutics

Recruiting

A First in Human Study of AX-202 in Healthy Subjects and Patients With Psoriasis.

Healthy Volunteers | Mild to Moderate Psoriasis

United Kingdom
Artery Therapeutics, Inc.
National Institute on Aging (NIA)

Recruiting

Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Alzheimer's Disease

Spain
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Allyx Therapeutics
Yale University; National Institute on Aging (NIA)

Recruiting

A Multiple Ascending Dose Study in Healthy Volunteers and Patients With Alzheimer's Disease

Alzheimer's Disease

United States
Intra-Cellular Therapies, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ITI 333 in Healthy Volunteers

Healthy Volunteers

United States
argenx

Recruiting

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Healthy Volunteers

Netherlands
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Safety,Tolerability,and Pharmacokinetics of Multiple-Ascending Dose JS1-1-01 in Healty Subjects.

Healthy Volunteers

China
ViiV Healthcare

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity

HIV Infections

United States
Afasci Inc

Recruiting

Phase I Single Ascending Dose and Multiple Ascending Doses of Oral AFA-281 in Healthy Volunteers

Pain, Neuropathic | Pain, Inflammatory

United States
Godavari Biorefineries Limited

Not yet recruiting

Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers

COVID-19

India
Keymed Biosciences Co.Ltd

Not yet recruiting

Multiple Ascending Dose Study of CM338 in Healthy Volunteers

Healthy Subjects
Fochon Pharmaceuticals, Ltd.

Recruiting

A Safety and Tolerability Study of FCN-207 in Healthy Volunteers

Hyperuricemia

China
Ono Pharmaceutical Co. Ltd

Completed

Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and PK of ONO-2910 in Japanese and Caucasian Subjects

Healthy Volunteers

Japan
Dompé Farmaceutici S.p.A

Terminated

Ascending Dose Tolerability Trial and PK Assessment in Healthy Volunteers After Single & Multiple Oral Intake of DF2755A

no Condition

France
Nuvamid SA
Medpace, Inc.; Anapharm; LGD

Active, not recruiting

Study of the Safety, Tolerability, and Pharmacokinetics of NUV001 Administered Orally to Healthy Adult Participants

Healthy Volunteers

United States
Pfizer

Active, not recruiting

A Preliminary Study to Evaluate PF-07264660 in Healthy Participants

Healthy

United States
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Terminated

The Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of BWC0977 in Healthy Adult Volunteers

Bacterial Infections | Infectious Diseases

Australia
Gasherbrum Bio, Inc

Active, not recruiting

A Study of Multiple-ascending Doses of GSBR-1290 in Healthy Overweight/Obese Participants

Healthy Volunteers

United States
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands
Ironwood Pharmaceuticals, Inc.

Completed

A Study of Multiple-ascending Doses of IW-3300 in Healthy Subjects

Healthy Volunteers

United States
Tempero Bio, Inc.
National Institute on Drug Abuse (NIDA)

Completed

Multiple Ascending Dose Study of TMP-301 in Healthy Subjects

Healthy Volunteers | Substance Use Disorders | Cocaine Use Disorder

United States
NeuroBo Pharmaceuticals Inc.

Completed

A Single and Multiple Ascending Dose Study of Niclosamide in Healthy Volunteers

Healthy

United States
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation
Crinetics Pharmaceuticals Inc.

Completed

Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers

Healthy Volunteers

United States
AstraZeneca
Parexel

Completed

A Study to Assess Safety, Tolerability, PK and PD of AZD2373 in Healthy Male Participants of Sub-Saharan West African Ancestry

Healthy Volunteers

United States
Nexel Co., Ltd.
Novotech (Australia) Pty Limited

Completed

A Study of NP-011 in Healthy Volunteers

Myocardial Infarction

Australia
Gasherbrum Bio, Inc

Completed

A Study of Multiple Ascending Doses of GSBR-1290 in Japanese and Non-Japanese Healthy Participants

Healthy Volunteers

United States
Xenon Pharmaceuticals Inc.

Completed

Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of XEN1101.

Healthy Volunteers

United Kingdom
LEO Pharma
ICON plc

Completed

A Single and Multiple Ascending-dose Trial of LEO 153339 in Healthy Adults

Healthy Volunteers

Netherlands
Gate Neurosciences, Inc

Completed

Multiple Ascending Dose and Electroencephalography Trial of GATE-202 in Healthy Volunteers

Major Depressive Disorder

United States
Sanofi

Completed

Single & Multiple Ascending Dose Study of SAR443820 in Healthy Adult Participants

Amyotrophic Lateral Sclerosis (Healthy Volunteers)

United States
Pyramid Biosciences

Completed

A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream

Psoriasis | Healthy Volunteers

United States
AstraZeneca

Completed

A Clinical Trial in Healthy Volunteers and Patients With Mild Asthma to Investigate a New Medicine (AZD4604) for the Treatment of Asthma

Asthma

United Kingdom
Haisco Pharmaceutical Group Co., Ltd.

Completed

A Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dosed of HSK36273 in Healthy Volunteers

Healthy

China
Haisco Pharmaceutical Group Co., Ltd.

Completed

Safety, Tolerability,PK/PD, Food Effect of Single and Multiple Ascending Doses of HSK31858 in Healthy Volunteers

Healthy Volunteers

China
Kymera Therapeutics, Inc.

Completed

A Single and Multiple Ascending Dose Trial of KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS)

Atopic Dermatitis | Healthy Volunteer | Hidradenitis Suppurativa

United States
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD5462 Following Single and Multiple Ascending Dose Administration to Healthy Volunteers

Healthy Participants

United States
Q32 Bio Inc.

Completed

Single and Multiple Ascending Dose Study of ADX-914 in Healthy Adult Volunteers

Safety Issues

Australia
Curacle Co., Ltd.
KCRN Research, LLC

Completed

First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers

Diabetic Macular Edema

United States
Cortexyme Inc.

Completed

A Single and Multiple Ascending Dose Study of COR588

Healthy Volunteers

Australia
SoftOx Solutions AS

Completed

Safety of Ascending Single and Multiple Doses of Nebulised SoftOx Inhalation Solution in Healthy Subjects

Healthy Volunteers | Safety

Denmark

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