Search clinical trials for: neglected diseases

Total 376343 results

R-Evolution Worldwide S.r.l. Impresa Sociale
University Ghent; National Institute for Medical Research, Tanzania; University... and other collaborators

Not yet recruiting

Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis (NeuroSolve)

Neurocysticercosis
Drugs for Neglected Diseases
Institute of Tropical Medicine, Belgium; Institut National de Recherche Biomédicale... and other collaborators

Not yet recruiting

Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT) (STROgHAT)

Human African Trypanosomiasis
Bioaster

Not yet recruiting

Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination (Obi1)

Healthy Volunteers | Onchocerciasis | Mansonelliasis | Loiasis

Cameroon
Tulane University
Tokyo Medical and Dental University; Centre Suisse de Recherches Scientifiques... and other collaborators

Recruiting

Digital Toolkit for Skin Diseases in LMICs: Part 2 (MIND-the-SKIN2)

Skin Diseases

Côte D'Ivoire
Drugs for Neglected Diseases
Novartis Pharmaceuticals

Recruiting

LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study

Primary Visceral Leishmaniasis

Ethiopia
University of Zurich

Not yet recruiting

Measuring the Prevalence of Toxoplasmosis and Its Socio-economic Consequences (EconToxo)

Toxoplasmosis | Rhd
Institute of Tropical Medicine, Belgium
University of Gondar

Recruiting

Clinical Prognostic Score to Predict Relapse in VL (CPS)

Visceral Leishmaniasis

Ethiopia
Drugs for Neglected Diseases
Novartis Pharmaceuticals

Recruiting

A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis

Primary Visceral Leishmaniasis

India
Murdoch Childrens Research Institute
Burnet Institute; Lao Tropical and Public Health Institute

Not yet recruiting

Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study) (ITCHY)

Scabies | Scabies; Itch

Lao People's Democratic Republic
Epicentre
Drugs for Neglected Diseases; European and Developing Countries Clinical Trials... and other collaborators

Recruiting

Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan (PKDL)

Leishmaniasis | Leishmaniasis, Visceral | Post-kala-azar Dermal Leishmaniasis

South Sudan
Drugs for Neglected Diseases

Recruiting

Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients (OXA005)

Trypanosomiasis, African | Sleeping Sickness | Trypanosoma Brucei Gambiense; Infection

Congo, The Democratic Republic of the
Tulane University
Osaka University; Centre Suisse de Recherches Scientifiques en Cote d'Ivoire; Institut Pasteur of Cote d'Ivoire and other collaborators

Recruiting

Digital Toolkit for Skin Diseases in LMICs (MIND-the-SKIN)

Skin Diseases

Côte D'Ivoire
Eijkman Oxford Clinical Research Unit, Indonesia
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy (MetLep)

Leprosy | Leprosy, Multibacillary | Neglected Tropical Diseases

Indonesia
Fundacion Agencia Aragonesa para la Investigacion...
GlaxoSmithKline; Universidad de Zaragoza; Instituto de Salud Carlos III; Université... and other collaborators

Recruiting

Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy (BLMs4BU)

Buruli Ulcer

Benin
Sohag University

Recruiting

Presentation And Management Of Neglected Inhaled Foreign Body At Sohag University Hospital

Foreign Body; Inhalation

Egypt
Laboratorio Elea Phoenix S.A.
Drugs for Neglected Diseases

Recruiting

Shorter Benznidazole Regimens Compared to the Standard Regimen for Chagas Disease (NuestroBen)

Chagas Disease

Argentina
London School of Hygiene and Tropical Medicine
Bandim Health Project; Medical Research Council Unit, The Gambia; Ministerio... and other collaborators

Recruiting

Adjunctive Ivermectin Mass Drug Administration for Malaria Control (MATAMAL)

Lymphatic Filariasis | Scabies | Malaria,Falciparum | Strongyloidiasis | Neglected Tropical Diseases | Hook Worm | Soil Transmitted Helminths

Guinea-Bissau
University Hospital Center of Martinique
Centre Hospitalier Universitaire de la Réunion; Centre Hospitalier de Cayenne; University Hospital of Guadeloupe and other collaborators

Recruiting

Comparing Two Antibiotic Therapy Periods (3 Versus 7 Days) in Patients With Mild Leptospirosis and Seen at the Hospital in 5 French Overseas Departments (Martinique, Guadeloupe, French Guiana, Reunion, Mayotte) (LEPTO3)

Mild Leptospirosis

Martinique, French Guiana, Guadeloupe, Mayotte, Réunion
Center for Research on Filariasis and Other Tropical...

Not yet recruiting

Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa (EOLoa)

Diagnoses Disease | Onchocerciasis | Neglected Diseases | Loiasis

Cameroon
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
National Human Genome Research Institute (NHGRI)
Therapeutics for Rare and Neglected Diseases (TRND)

Recruiting

A Natural History Study of Patients With GNE Myopathy and GNE-Related Diseases

GNE Myopathy | GNE Related Diseases

United States
University of Texas, El Paso
National Institute of Allergy and Infectious Diseases (NIAID); Drugs for Neglected... and other collaborators

Active, not recruiting

New Therapies and Biomarkers for Chagas Infection (TESEO)

Chagas Disease | Trypanosoma Cruzi Infection

Bolivia
London School of Hygiene and Tropical Medicine
AIM Initiative; Ministry of Health, Liberia

Completed

Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia

Yaws | Leprosy | Lymphatic Filariases | Buruli Ulcer

Liberia
Drugs for Neglected Diseases
Sanofi

Completed

Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage

Trypanosomiasis, African | Sleeping Sickness | Trypanosomiasis; Gambian

Congo, The Democratic Republic of the, Guinea
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Institute of Tropical Medicine, Belgium
University Hospital, Antwerp; Maastricht University; University of York; University...

Active, not recruiting

Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in Ethiopia (SpatialCL)

Cutaneous Leishmaniases

Ethiopia
Jennifer Keiser
Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health...

Completed

Efficacy of Ivermectin-albendazole vs Albendazole Alone in School-aged Children Infected With Trichuris Trichiura (FACEITeffic)

Trichuriasis

Uganda
Pemba Ministry of Health Zanzibar

Active, not recruiting

Health Education Model Led by Community Health Volunteers.

Health Education | Schistosomiasis

Tanzania
Drugs for Neglected Diseases
Bayer

Active, not recruiting

Emodepside Phase II Trial for Treatment of Onchocerciasis

Onchocerciasis

Ghana, Congo, The Democratic Republic of the
Drugs for Neglected Diseases
Makerere University; The Netherlands Cancer Institute; Kenya Medical Research... and other collaborators

Completed

Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa

Visceral Leishmaniasis

Ethiopia, Kenya, Sudan, Uganda
Drugs for Neglected Diseases

Active, not recruiting

Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World

Cutaneous Leishmaniases

Peru, Bolivia, Brazil, Panama
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Institut National de Recherche Biomédicale. Kinshasa... and other collaborators

Withdrawn

Screen and Treat Implementation for HAT Control

Trypanosomiasis, African | Sleeping Sickness
Technical University of Munich
Swiss Tropical & Public Health Institute; Makerere University; European and Developing... and other collaborators

Active, not recruiting

Adoption of L-PZQ for Schistosomiasis by Endemic Counties - Social Science Research Study (ADOPT)

Social Acceptance | Schistosomiasis in Children

Uganda, Kenya, Côte D'Ivoire
Institute of Tropical Medicine, Belgium

Completed

Assessment of Recombinant HAT-RDT Specificity

Human African Trypanosomiasis

Congo, The Democratic Republic of the
AbbVie
Drugs for Neglected Diseases initiative

Terminated

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection

Onchocerciasis

Congo, The Democratic Republic of the
Drugs for Neglected Diseases

Completed

Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects (OXA004)

Trypanosomiasis, African | Sleeping Sickness | Trypanosoma Brucei Gambiense; Infection

Congo, The Democratic Republic of the, Guinea
Drugs for Neglected Diseases

Completed

DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan (OXA-07)

Trypanosomiasis, African

Malaysia
Washington State University
University of Glasgow; National Institute for Medical Research, Tanzania

Completed

Integrating Community Interventions to Eliminate Neglected Tropical Diseases

Rabies in Animals | Worms; Intestine

United States
Drugs for Neglected Diseases
Wellcome Trust grant 212346/Z/18/Z - 21st Century Treatments for Sustainable...

Completed

Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects

Visceral Leishmaniasis | Cutaneous Leishmaniases

United Kingdom
Swiss Tropical & Public Health Institute
Drugs for Neglected Diseases; Ifakara Health Institute

Completed

PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets (HELP-OFZ)

Filariasis

Tanzania
Drugs for Neglected Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Efficacy and Safety of Fexinidazole in Patients With Human African Trypanosomiasis (HAT) Due to Trypanosoma Brucei Rhodesiense

Trypanosoma Brucei Rhodesiense; Infection

Malawi, Uganda
Institute of Tropical Medicine, Belgium
Medecins Sans Frontieres, Netherlands; University of Gondar, Gondar, Ethiopia; Bureau of Health, Abdurafi, Ethiopia

Terminated

Predicting Visceral Leishmaniasis in HIV Infected Patients (PreLeisH)

Leishmaniasis, Visceral

Ethiopia
Foundation for Innovative New Diagnostics, Switzerland
London School of Hygiene and Tropical Medicine; Academisch Medisch Centrum... and other collaborators

Completed

Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern Africa (VL-DX-EAFR)

Leishmaniasis, Visceral

Ethiopia, Kenya
Drugs for Neglected Diseases

Completed

Prospective Study on Efficacy and Safety of Acoziborole (SCYX-7158) in Patients Infected by Human African Trypanosomiasis Due to T.b. Gambiense (OXA002)

Trypanosomiasis, African | Gambiense Trypanosomiasis | Sleeping Sickness

Congo, The Democratic Republic of the, Guinea
FHI 360
National Program for the Fight Against Neglected Tropical Diseases, Côte...

Completed

Resiliency Through Azithromycin for Children (REACH), Côte d'Ivoire (REACH)

Child Mortality | Azithromycin

Côte D'Ivoire
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
Baxalta now part of Shire
National Heart, Lung, and Blood Institute (NHLBI); SAIC-Frederick, Inc.; Cato... and other collaborators

Completed

A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease

United States
Drugs for Neglected Diseases

Completed

ADME Study of Acoziborole in Healthy Subjects

Trypanosomiases, African

United Kingdom
Drugs for Neglected Diseases
Ministry of Health, Malaysia; Ministry of Health, Thailand; National Science...

Active, not recruiting

Strategic Transformation of the Market of HCV Treatments (STORM-C-1)

Hepatitis C

Malaysia, Thailand
Baylor College of Medicine
George Washington University; Amsterdam Institute for Global Health and Development and other collaborators

Completed

Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults

Hookworm Infection | Hookworm Disease

Gabon

Search clinical trials for: neglected diseases

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