Search clinical trials for: opioid pharmacology

Total 8525 results

Clinical Centre of Serbia
Faculty of Medicine, University of Belgrade

Recruiting

Oxidative Stress and Inflammation Biomarkers in Surgically Treated Patients With Laryngeal Cancer

Quality of Life | Pain, Postoperative | Laryngeal Cancer | Pain Management | Oxidative Stress Induction | Interleukins

Serbia
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Measuring Acute Drug Demand in Humans

Opioid Use Disorder | Opioid Dependence

United States
William Stoops
National Institute on Drug Abuse (NIDA)

Recruiting

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine) (BED IN 43)

Opioid Use Disorder | Cocaine Use Disorder

United States
Johns Hopkins University

Recruiting

Suvorexant for Opioid/Stimulant Co-use

Opioid Use Disorder | Stimulant Use Disorder

United States
Johns Hopkins University

Recruiting

Evaluating Buspirone to Treat Opioid Withdrawal

Anxiety | Opioid Use Disorder | Opioid Withdrawal | Opioid Craving

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Developing a Clinical Outcome Assessment for Opioid Craving

Opioid Use Disorder | Opioid Craving | Measure Development

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

An Innovative Intervention for OUD Treatment (Bridge)

Opioid-Related Disorders | Opioid Dependence | Opioid Withdrawal | Opioid Addiction

United States
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder

Sleep Disturbance | Opioid-use Disorder

United States
Joshua A. Lile, Ph.D.
National Institute on Drug Abuse (NIDA)

Recruiting

Neurobehavioral Mechanisms of Choice in Opioid Use Disorder

Opioid Use Disorder

United States
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
Pfizer

Terminated

Tanezumab In Osteoarthritis Of The Hip Or Knee

Osteoarthritis

United States, Spain, Germany, Poland, Denmark, Austria, Sweden
Seattle Institute for Biomedical and Clinical Research
United States Department of Defense; VA Puget Sound Health Care System

Completed

Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders (PaN)

Alcohol Use Disorder | Posttraumatic Stress Disorder (PTSD)

United States
University of Southern Denmark

Completed

Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

Metformin | Organic Cation Transporter 1 | Codeine

Denmark
Mallinckrodt

Terminated

Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients

Chronic Pain

United States
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)

Pharmacokinetic

Belgium
Grünenthal GmbH

Completed

Pharmacokinetic Characterization of Two Novel CG5503 Tablet Formulations in Healthy Volunteers

Pharmacokinetics

Germany
Johns Hopkins University

Completed

Effects of Hallucinogens and Other Drugs on Mood and Performance

Healthy

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
Wei Hao
Shanghai Mental Health Center; West China Hospital; Wuhan Mental Health Centre; Beijing ziduhongye technology development co. LTD and other collaborators

Unknown

A Study of Thienorphine Hydrochloride Tablets in Relapse Prevention Treatment of Opioid Dependence

Opioid Dependence
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid (OPI-15-001)

Drug Overdose

Norway
Eunice Kennedy Shriver National Institute of Child...

Completed

Codeine in Mechanically Ventilated Neonates

Mechanically Ventilated Neonates | Painful Procedures in Newborns

United States
Hopital Foch

Completed

Closed-loop Anaesthesia for Liver Transplantation: a Pilot Study (THConcentr)

Anesthesia | Liver Transplant

France
National Institute on Drug Abuse (NIDA)

Completed

The Discriminative Effects of Tramadol in Humans

Opioid Abuse | Opioid Addiction | Stimulant Abuse | Stimulant Addiction

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil (0813)

Hyperalgesia

United States
Johns Hopkins University

Completed

Recovery Housing and Drug Abuse Treatment Outcome

Opiate Addiction | Mental and Behavioral Disorders Due to Use of Cocaine: Harmful Use

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

Pain | Addiction | Opioid Dependence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain (1401)

Chronic Pain | Opioid-Related Disorders

United States
Pfizer

Completed

A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain

Low Back Pain | Chronic Pain | Analgesia

United States
Medical University of Vienna

Completed

Drug Drug Interactions of Aspirin and P2Y12-inhibitors

Myocardial Infarction | Drug Interaction Potentiation

Austria
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals

Opioid Dependence | Opioid Abuse

United States
Indivior Inc.

Completed

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Hepatic Impairment | Hepatic Failure | Chronic Hepatitis C Infection With Hepatic Coma

United States
Seoul National University Hospital

Completed

Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass

Cardiopulmonary Bypass | Pharmacology | Anesthetics, Intravenous | Anesthetics

Korea, Republic of
Pain Therapeutics

Completed

Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse

Opioid-Related Disorders

United States
INSYS Therapeutics Inc

Completed

Fentanyl Sublingual Spray in Opioid Naive Participants

Pharmacology

United States
Matthias Schwab

Completed

Open Label Study for the Functional Characterization of Drug Metabolism and Transport (IKP243)

Genotype-related Drug Metabolism

Germany
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Tramadol as a Treatment for Opioid Addiction

Opioid-Related Disorders

United States
Cephalon

Completed

Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for Management of Breakthrough Pain

Chronic Low Back Pain

United States
Cephalon

Completed

Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for the Management of Breakthrough Pain

Chronic Neuropathic Pain

United States
Institut fuer anwendungsorientierte Forschung und...

Completed

Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics

Membrane Transport | Drug Biotransformation

Germany
Purdue Pharma LP

Completed

Safety and Efficacy of Dose Conversion From Vicodin® to Buprenorphine Transdermal System (Butrans™) in Subjects With OA Pain

Osteoarthritis

United States
Purdue Pharma LP

Completed

Examine Plasma Concentrations of Buprenorphine Following Reapplication of Buprenorphine Transdermal System (BTDS) After Variable Application Site Rest Periods

Healthy

United States
Cephalon

Completed

OraVescent Fentanyl (OVF) for the Treatment of Breakthrough Pain in Opioid Tolerant Cancer Patients

Pain | Cancer

United States
Cephalon

Completed

A Study to Assess the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Renal Function and Subjects With Varying Degrees of Renal Impairment

Renal Impairment

United States
Abbott

Completed

Remission in Subjects With Crohn's Disease, 1 Year Phase (CLASSICII)

Crohn's Disease

United States
University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
California Pacific Medical Center Research Institute

Completed

Safety Study of Intravenous 6β-Naltrexol (AIKO-150) in Opioid-Dependent Subjects (AIKO-150)

Opiate Addiction

United States
University of Southern Denmark
H. Lundbeck A/S

Completed

The Effect of Escitalopram on the Pharmacokinetics and Pharmacodynamics of Tramadol in Healthy Subjects

Healthy

Denmark
Radboud University Medical Center

Suspended

Opioid Receptors Influence Ischemia-Reperfusion Injury

Ischemia-Reperfusion Injury

Netherlands
Odense University Hospital

Completed

OXY-2: The Pharmacogenetics of Oxycodone Analgesia in Human Experimental Pain Models

Healthy

Denmark
Johns Hopkins University

Completed

Opioid Maintenance Medications Comparison Study

Opioid Dependence

United States

Search clinical trials for: opioid pharmacology

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