Search clinical trials for: opioid-induced constipation (OIC)

Total 1063 results

University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CommunityRx-Cardiovascular Disease (CRx-CVD)

Cardiovascular Diseases | Self Efficacy

United States
TriHealth Inc.

Recruiting

Naloxegol and Opioid-induced Constipation

Constipation | Constipation Drug Induced

United States
Bausch Health Americas, Inc.
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of Methylnaltrexone (MNTX) for the Relief of Constipation

Advance Illness Patients With OIC

United States
Theravance Biopharma

Completed

TD-1211 IV/Oral Mass Balance Study

OIC

United States
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 2 Project (StOIC-2)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
Bausch Health Americas, Inc.

Completed

Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain

Constipation

United States
Legend Labz, Inc.

Recruiting

Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility

Safety Issues

United States
University of North Carolina, Chapel Hill
Centers for Disease Control and Prevention

Completed

Carolina Heart Alliance Networking for Greater Equity (CHANGE)

Cardiovascular Disease (CVD)

United States
Bausch Health Americas, Inc.

Completed

Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC) (OIC)

Constipation

United States
Legend Labz, Inc.

Recruiting

A Sub-Chronic Evaluation of the Safety of Celastrol in Human Subjects

Safety

United States
Galmed Pharmaceuticals Ltd
Quotient Sciences

Completed

An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol

NASH

United Kingdom
AstraZeneca

Terminated

Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain

Opioid-Induced Constipation

Croatia, United States, Bulgaria, United Kingdom, Poland, Romania, Belgium, Puerto Rico, Slovakia, Australia, South Africa, Czech Republic, Germany, Spain
AstraZeneca

Completed

Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Opioid-Induced Constipation (OIC)

Croatia, Sweden, United States, Czech Republic, Spain, Hungary, United Kingdom, Belgium
Chinese University of Hong Kong

Not yet recruiting

Evaluating an Innovative HIV Self-testing Service With Counseling Provided by a Chatbot

Behaviors, Health

Hong Kong
Theravance Biopharma

Completed

A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC)

Opioid Induced Constipation

United States
RAND
Boston University; Clinical Directors Network

Recruiting

Building Experience for Treating Trauma and Enhancing Resilience (BETTER) (BETTER)

PTSD

United States
Methodist Health System

Withdrawn

RELISTOR's Effects on Opioid-Induced Constipation

OIC

United States
AstraZeneca

Completed

A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Opioid-Induced Constipation (OIC)

United States, Germany, Australia, Slovakia
AstraZeneca
Nektar Therapeutics

Completed

A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)

Opioid Induced Constipation (OIC)

United States
Theravance Biopharma

Completed

A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation

Opioid-induced Constipation (OIC)

United States
Charlotte-Paige Rolle, MD
ViiV Healthcare

Completed

Efficacy of Switching to DTG/3TC in Virologically-suppressed Adults Currently on B/F/TAF (DYAD)

HIV I Infection

United States
Hospital de Granollers

Completed

Gaps Between Evidence and Practice in Prevention of Surgical Site Infection in Spain (SurveyOIC)

Surgical Site Infection

Spain
Alkermes, Inc.

Completed

ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)

OIC

United States
Kyowa Kirin Pharmaceutical Development Ltd

Completed

Phase I Pharmacokinetics and Safety Study of Naloxegol in Paediatric OIC Patients

Constipation, Signs and Symptoms, Digestive

United Kingdom, Denmark, Norway, Israel, Spain
Shionogi

Recruiting

Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

Opioid-Induced Constipation (OIC)

France
AstraZeneca

Completed

Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Opioid-Induced Constipation (OIC)

United States, Australia, Slovakia, Germany
AstraZeneca

Completed

Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Opioid-Induced Constipation (OIC)

United States
Theravance Biopharma

Completed

A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation

Opioid Induced Constipation

United States
BioDelivery Sciences International
HealthCore, Inc.

Recruiting

Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain

Opioid-induced Constipation

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Colonic Motor Patterns in Healthy Volunteers (NaloxegolHRM)

Opioid-Induced Constipation

Belgium
Nanometics (d.b.a. PHD Biosciences)

Completed

Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome

Breast Cancer | Palmar-Plantar Erythrodysesthesia

United States
Washington University School of Medicine
University of Colorado, Denver; University of California, Berkeley; University... and other collaborators

Active, not recruiting

ADAPT for Adolescents Adolescents (A4A)

HIV/AIDS

Kenya
Galmed Medical Reserch

Completed

A Phase 1 Single and Multiple-Dose Study of Aramchol in Healthy Male Volunteers

Healthy

Israel
Hospice of Henderson County, Inc.
AstraZeneca

Terminated

Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)

Pain | Cancer | Constipation

United States
Kyowa Kirin Pharmaceutical Development Ltd
Apices Soluciones S.L.

Completed

Real World Observational Study of Naloxegol for Patients With Cancer Pain Diagnosed With OIC. (NACASY)

Opioid Induced Constipation

Netherlands, Sweden, Finland, Denmark, Spain, France, Germany, Greece, Italy, United Kingdom
Shire

Terminated

Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation (OIC)

Opioid Induced Constipation | Non-cancer Pain

Belgium
Alkermes, Inc.

Completed

ALK37-005: A Study of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)

Opioid-induced Constipation

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Alkermes, Inc.

Completed

ALK37-003: A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation (OIC)

Opioid-induced Constipation

United States
Cubist Pharmaceuticals LLC

Terminated

Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

Opioid-Induced Constipation
Cubist Pharmaceuticals LLC

Terminated

Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

Opioid-Induced Constipation
Bausch Health Americas, Inc.
Progenics Pharmaceuticals, Inc.

Completed

Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain

Constipation

United States
Bausch Health Americas, Inc.
Progenics Pharmaceuticals, Inc.

Completed

A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain

Opioid-Induced Constipation

United States
Cubist Pharmaceuticals LLC

Terminated

The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

Opioid-Induced Constipation
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
Mundipharma Research GmbH & Co KG

Completed

A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC).

Opioid Induced Constipation

Sweden
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
University of California, Davis

Withdrawn

A Study Of Ursolic Acid For Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis

United States
Theratechnologies
ICON Clinical Research; Excelsus Statistics Inc.; Health Psychology Research...

Recruiting

A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab (PROMISE-US)

HIV Infections | Multi-Antiviral Resistance

United States
Merck Sharp & Dohme LLC

Completed

Islatravir (MK-8591) With Doravirine and Lamivudine in Participants Infected With Human Immunodeficiency Virus Type 1 (MK-8591-011)

HIV-1 Infection

United States, Chile, France, United Kingdom

Search clinical trials for: opioid-induced constipation (OIC)

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