Search clinical trials for: peripheral effects of withdrawal

Total 430962 results

National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

B Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage
National Institute of Respiratory Diseases, Mexico

Recruiting

Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects

Tobacco Smoking | Nicotine Addiction | Nicotine Withdrawal | Nicotine Replacement Therapy | Tobacco Withdrawal

Mexico
Chang Gung Memorial Hospital

Not yet recruiting

Reduction of Rocuronium-induced Injection Pain With Aspiration of Blood

Anesthesia, General
National Cancer Institute (NCI)

Not yet recruiting

A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia
Takeda

Recruiting

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period

Plaque Psoriasis

United States, Canada, Bulgaria, Hungary
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Evaluation of the Electronic Cigarette Withdrawal Syndrome

Withdrawal | E-cigarette Use

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetic and Safety Study of Oral Lofexidine in Neonates Experiencing Opioid Withdrawal Due to Intrauterine Exposure to Opioids

Opioid Withdrawal (Disorder)

United States
First Affiliated Hospital of Wenzhou Medical University

Recruiting

Early and Late Prognosis in Patients With Guillain-Barre Syndrome

Guillain-Barre Syndrome

China
University of Pennsylvania

Recruiting

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal (UH3)

Opioid Use | Opiate Withdrawal Syndrome

United States
HELP for NOWS Consortium
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Optimizing Pharmacologic Treatment for Neonatal Opioid Withdrawal Syndrome (OPTimize NOW): A Symptom-Based Dosing Approach (OPTimize NOW)

Neonatal Opiate Withdrawal Syndrome

United States
Shenzhen Kangning Hospital

Not yet recruiting

Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism

Tobacco Use Disorder

China
Salem Anaesthesia Pain Clinic

Recruiting

Kratom Use Disorder Management Using Clonidine and/or Buprenorphine

Withdrawal Syndrome

Canada
Washington University School of Medicine

Recruiting

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE) (Patch BRIDGE)

Pregnancy Complications | Pregnancy Related | Pregnancy, High Risk | Opioid Use Disorder | Buprenorphine Withdrawal

United States
University Hospital Schleswig-Holstein
Michael J. Fox Foundation for Parkinson's Research

Recruiting

Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes (SensoMo-PD)

Dystonia | Parkinson | Dystonia, Familial | DYT3 | DYT5 | PINK1 Gene Deletion

Germany
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA); Yale University; Clinilabs, Inc.; BioXcel...

Recruiting

Sublingual Dexmedetomidine for Treating Opioid Withdrawal

Opioid Use Disorder | Opioid Withdrawal

United States
Rush University Medical Center
Medical University of South Carolina

Recruiting

Overcoming Nicotine Dependence to Enable Quitting (ON-DEQ)

Smoking Cessation | Tobacco Use | Nicotine Dependence | Smoking Behaviors | Nicotine Withdrawal

United States
Johns Hopkins University

Recruiting

Evaluating Buspirone to Treat Opioid Withdrawal

Anxiety | Opioid Use Disorder | Opioid Withdrawal | Opioid Craving

United States
AstraZeneca
Daiichi Sankyo

Recruiting

Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Endometrial Cancer | Urothelial Cancer | Biliary Tract Cancer | Metastatic Castration-resistant Prostate Cancer

Spain, China, Korea, Republic of, Canada, Italy, Poland, Turkey, United Kingdom, Japan, Taiwan, United States, France, Germany, Switzerland
King Abdullah International Medical Research Center

Recruiting

Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs. (PROMISE)

Dexmedetomidine | Withdrawal Symptoms | Midazolam | Failure of Extubation

Saudi Arabia
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers

Drug Effect | Nicotine Addiction | Nicotine Withdrawal

United States
United Health Services Hospitals, Inc.
Binghamton University

Recruiting

Evaluating the Pharmacokinetics and Patient Outcomes of Buprenorphine Microdosing

Opioid Use Disorder | Opioid Withdrawal

United States
Neuromed IRCCS
University of Rome Tor Vergata

Not yet recruiting

Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

Healthy | Neuromyelitis Optica | Relapsing-Remitting Multiple Sclerosis (RRMS)

Italy
Spark Biomedical, Inc.
Hazelden Betty Ford Foundation; Gaudenzia, Inc.

Recruiting

Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder (RESTORE)

Opioid-use Disorder | Opioid Withdrawal

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Opioid Use Disorder | Opioid Withdrawal | Opioid Craving

United States
Peking University

Recruiting

Sedation Compaired With Anesthesia With THRIVE in Endotracheal Intubation With Difficult Airways

Airway Control | Sedative, Hypnotic, or Anxiolytic Withdrawal

China
University of Erlangen-Nürnberg Medical School

Recruiting

Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis

Psoriatic Arthritis | Withdrawal | Reduction

Germany
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

An Innovative Intervention for OUD Treatment (Bridge)

Opioid-Related Disorders | Opioid Dependence | Opioid Withdrawal | Opioid Addiction

United States
University of British Columbia
Vancouver Coastal Health

Recruiting

Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder

Opioid Use Disorder

Canada
Massachusetts General Hospital
University of Southampton; Spina, Stefano, M.D., Massachusetts General Hospital and other collaborators

Recruiting

Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients

Cardiovascular Diseases | Endothelial Dysfunction | Oxidative Stress

United States, United Kingdom
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
Yonsei University

Not yet recruiting

Aspirin Withdrawal and Clinical Outcome in Patients With Moderate to High Cardiovascular Risk But Without Cardiovascular Disease

Healthy Participants With Moderate and High Cardiovascular Risk

Korea, Republic of
Hvidovre University Hospital

Recruiting

Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma

Asthma

Denmark
National University Hospital, Singapore

Recruiting

Pre-operative Withdrawal of Aspirin in Laparoscopic Inguinal Hernia Repair

Inguinal Hernia

Singapore
University of Pennsylvania

Completed

Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal (PGB-LOF)

Opioid Withdrawal

United States
BioXcel Therapeutics Inc
Lotus Clinical Research, LLC

Completed

Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder

Schizophrenia | Bipolar Disorder | Schizo Affective Disorder | Agitation,Psychomotor | Schizophreniform Disorders

United States
NYU Langone Health

Active, not recruiting

Electronic Cigarettes as a Harm Reduction Strategy Among People Living With HIV/AIDS

Nicotine Addiction

United States
The University of Texas Health Science Center,...

Completed

Protocolized Initiation of Clonidine to Prevent Dexmedetomidine Withdrawal

Withdrawal; Therapeutic Substance

United States
Meir Medical Center

Completed

Methadone vs. Transdermal Fentanyl for Opioid Withdrawal Syndrome

Delirium in the Intensive Care Unit

Israel
Advancing Clinical Trials in Neonatal Opioid Withdrawal...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

Neonatal Opioid Withdrawal Syndrome

United States
Centre Hospitalier Universitaire Dijon

Completed

Effectiveness of Transcranial Magnetic Stimulation (TMS) in Smoking Cessation, Combining Withdrawal Stimulation Followed by Maintenance Stimulation to Prevent Relapse. (TabacStim2)

Smoking Cessation

France
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR); Ontario Ministry of Health and...

Completed

Remote Treatment of Alcohol Withdrawal

Alcohol Withdrawal

Canada
University of Vermont
National Institute on Drug Abuse (NIDA); Johns Hopkins University; University... and other collaborators

Completed

Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions (MOTHER DYAD)

Opioid-use Disorder | Neonatal Abstinence Syndrome | Opioid Withdrawal | Neonatal Opioid Withdrawal Syndrome

United States
University of Vermont
National Institute on Drug Abuse (NIDA); Food and Drug Administration (FDA); University...

Active, not recruiting

Project 4, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Pregnant Women

Tobacco Use Disorder

United States
PleoPharma, Inc.

Completed

Effect of PP-01 on Cannabis Withdrawal Syndrome

Cannabis Withdrawal

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study (MOMs-CMA)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
Iovate Health Sciences International Inc
Citruslabs

Completed

Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus

Caffeine Withdrawal | Energy | Focus

United States
Unity Health Toronto

Terminated

Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome (PHENOMANAL)

Alcohol Withdrawal | Alcohol Withdrawal Delirium | Alcohol Withdrawal Seizures

Canada
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
Dhaka Medical College

Enrolling by invitation

The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy

Focal Epilepsy

Bangladesh
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States

Search clinical trials for: peripheral effects of withdrawal

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