Search clinical trials for: pharmacokinetics

Total 10302 results

Genentech, Inc.

Recruiting

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Colorectal Cancer | Non-Small Cell Lung Cancer

Korea, Republic of, Australia, Canada, United States
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1543 in Healthy Adult Volunteers

Healthy Volunteers
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1543 With DWC202307 in Healthy Adult Volunteers

Healthy Volunteers
The Affiliated Hospital of Qingdao University

Recruiting

Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial

Gastric Cancer

China
Bozyaka Training and Research Hospital

Recruiting

The Effect of Anesthetic Methods on Gastrointestinal Motility

Anesthesia | Total Intravenous Anesthesia

Turkey
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subjects in China

Pharmacokinetics

China
St George's, University of London
University College, London

Recruiting

Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK) (MD-PK)

Sepsis | Critical Illness | Septic Shock | Bacteremia | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Adult Children

United Kingdom
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Study to Evaluate the Pharmacokinetics of HSK21542 in Subjects With Renal Impairment

Renal Impairment

China
Hansoh BioMedical R&D Company

Recruiting

A First in Human Study to Evaluate Safety, Tolerability, Pharmacology of HS-10390 in Healthy Subjects

Focal Segmental Glomerulosclerosis | IgA Nephropathy

China
Pharmosa Biopharm Inc.
Novotech (Australia) Pty Limited

Recruiting

Safety, Tolerability and Pharmacokinetics of L608 in Healthy Adults

Pulmonary Arterial Hypertension

Australia
CSL Behring

Recruiting

First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Complement Deficiencies

Australia
Eduardo Schiffer

Not yet recruiting

Dexmedetomidine and Kidney Transplantation (DexTR)

Dexmedetomidine | Renal Transplantation
Cerevel Therapeutics, LLC

Recruiting

A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Emraclidine

Hepatic Impairment

United States
Shanxi Kangbao Biological Product Co., Ltd.
Institute of Pathogen Biology, Chinese Academy of Medical Sciences

Recruiting

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects

Hiv

China
Cerevel Therapeutics, LLC

Recruiting

A Study Evaluating the Pharmacokinetics and Relative Bioavailability of Emraclidine Immediate-Release Tablets in Healthy Adult Participants

Healthy Participants

United States
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SHR-2017 Injection in Postmenopausal Women

Osteoporosis

China
CJ CheilJedang

Not yet recruiting

Pharmacokinetic Profile of Rosemary Extract Supplement

Pharmacokinetics
Dizal Pharmaceuticals

Recruiting

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Non-small Cell Lung Cancer

China
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients

Metastatic Pancreatic Cancer

Singapore
University of Iowa

Recruiting

Pharmacokinetics of Transdermal Metronidazole

Healthy

United States
Genentech, Inc.

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Relapsed or Refractory Multiple Myeloma

Korea, Republic of, Australia, Israel
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

BTZ-043 Dose Evaluation in Combination and Selection (DECISION)

Tuberculosis, Pulmonary | Other Specified Pulmonary Tuberculosis

South Africa, Tanzania
Hoffmann-La Roche

Recruiting

A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic Parkinson's Disease

Parkinson Disease

United States, Netherlands, United Kingdom
Pfizer

Recruiting

A Study for Two Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
GlaxoSmithKline

Not yet recruiting

A Study of Belimumab in Chinese Pediatric Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Eli Lilly and Company

Recruiting

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Zydus Lifesciences Limited

Not yet recruiting

A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carriers

Asymptomatic Condition | Falciparum Malaria | Uncomplicated Malaria
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022

Hyperlipemia

China
Crinetics Pharmaceuticals Inc.

Recruiting

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

Congenital Adrenal Hyperplasia | Classic Congenital Adrenal Hyperplasia

Brazil, India, United States, Argentina, Italy, United Kingdom
Yale University
National Institute on Drug Abuse (NIDA); VA Connecticut Healthcare System

Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Pain, Tolerance | Oral vs Vaporized THC | Abuse Liability

United States
Celltrion

Not yet recruiting

A Study to Compare Efficacy, Pharmacokinetics, Pharmacodynamics and Safety of CT-P53 and Ocrevus in Patients With Relapsing-remitting Multiple Sclerosis

Relapsing-remitting Multiple Sclerosis
Ikaria Bioscience Pty Ltd

Recruiting

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

To Reduce the LDL-C Level in Hypercholesteremia Adult Patients | Combination for Subgroup High LDL-c Patients With Other Comorbidities

Australia
BeiGene

Recruiting

A Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BGB-30813

Advanced Solid Tumors

United States, Australia, Spain
Ryazan State Medical University

Recruiting

Clinical One-stage Controlled Study of reSistant Arterial Hypertension for the desiGning of a personAlized Approach to Therapy (SAGA)

Resistant Arterial Hypertension

Russian Federation
GeneScience Pharmaceuticals Co., Ltd.
Afﬁliated Hospital of North Sichuan Medical College

Recruiting

Clinical Study of Multiple Dose Genakumab for Injection in Chinese Healthy Adults

Interstitial Lung Disease

China
Peking University Third Hospital

Recruiting

Pharmacokinetics of Clinical Probes and Characteristics of Endogenous Biomarker in Chinese Older Adults

Aging

China
Amgen

Recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Vifor Fresenius Medical Care Renal Pharma
Tigermed Consulting Co., Ltd

Recruiting

Pharmacokinetics of Intravenous Difelikefalin in Chinese Adult Subjects on Haemodialysis

End Stage Renal Disease on Hemodialysis

China
Eli Lilly and Company

Recruiting

A Study of LY3502970 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Spinogenix
Novotech (Australia) Pty Limited

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPG302 in Healthy Volunteers and ALS Participants

Amyotrophic Lateral Sclerosis

Australia
Bio-Thera Solutions
Zhejiang Tumor Hospital

Recruiting

To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Johns Hopkins University
DEKA S.r.l.

Not yet recruiting

Blood Naloxone Levels Following Intradermal Injection in Humans

Opioid Overdose
The Second Affiliated Hospital of Chongqing Medical...

Recruiting

Precision Drug Use of Immunosuppressants Guided by Population Pharmacokinetics/Pharmacodynamic Models in Kidney Transplant Patients

Kidney Transplantation | Immunosuppressive Agents

China
Genentech, Inc.
Chugai Pharmaceutical Co.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-Care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

Gastric Cancer | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma

Korea, Republic of, Spain, Japan, New Zealand, Australia, United States, Italy, Brazil
Aneira Pharma, Inc.
DataPharm Australia, CMAX Clinical Research, Agilex Australia

Not yet recruiting

Phase I Study of Safety and Pharmacokinetics of Topical Solution in Subjects With Androgenetic Alopecia

Androgenetic Alopecia
Vertex Pharmaceuticals Incorporated

Recruiting

A Study to Evaluate Pharmacokinetics (PK) and Safety of Inaxaplin in Participants With Renal Impairment

Renal Impairment

United States
AstraZeneca

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD7503 in Participants With Suspected NASH.

Steatohepatitis

United States, Puerto Rico
HighField Biopharmaceuticals Corporation

Recruiting

A Clinical Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HF158K1 in Participants With HER-2 Positive or HER-2 Low Expression Advanced Solid Tumors

Solid Tumors, Adult

China, United States
Afimmune

Recruiting

Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

Sickle Cell Disease

United States

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